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The map label for this gene is yrbI [C]

Identifier: 193214292

GI number: 193214292

Start: 670602

End: 671153

Strand: Direct

Name: yrbI [C]

Synonym: Ctha_0573

Alternate gene names: 193214292

Gene position: 670602-671153 (Clockwise)

Preceding gene: 193214291

Following gene: 193214293

Centisome position: 20.36

GC content: 50.18

Gene sequence:

>552_bases
TTGGAAATATTCGGCGTTTCAGTTTCGTCAGAAGATCCGACTTCCCGCTTGCGGCAGCTGCTCGGCGAGATCAAGGTGAT
TATCTTTACAATCGACGGTGTTTTCACCGATGGCCAAATTAGTTATAGCGAATCCGGCGAGGAAGTTCGGACTTTTCATG
CTCGCGACGGATTTGCTATTCAGGAAGCACTTGCAAAAGGCATGAACATTGCCGTGGTTTCCGAGCGCGAATCTAAAGCG
GCTCGCAAACGCCTTGAAGAAATCGGCGTTACCGACATCACGATGGGCGTCAAAGATAAAATGCCGACCTACGAAGCCAT
CAAAGCGCGTTATGGCGTTAGCGACGCGGAATGCGTCTACATCGGCGACGATGTGATGGATCTTCCCTTGTTTGAGAAAG
TCGGCGTATCCATTACGCCACTGAACGGCGTGGAATATCTTCGCAATCGGGTTTACTATGTTTCCGGCTACGAAGGCGGA
AAAGGCTGCGTGCGCGATGTGATCGAAATGGTGCTCGCCATTCAAGGCAAATGGAAATACTACGAAATGTAG

Upstream 100 bases:

>100_bases
TCCGCTTTCCAAAGCAGAACCGCTGCTGCGCGAACTTCAAGAAATATTTGAGATAACAAAAAAAATTCAACCATTAATCT
AAGACAGAGGATAGAGAAAA

Downstream 100 bases:

>100_bases
ATTTTTAGGCAAATGCTTCCCCCGAAAAATCTAACTTCAAACAGGAAGCATTTGCCGCTTTTTATGCCGCTCTACGCCGG
AAATCTTTTCTCACTTTATC

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MEIFGVSVSSEDPTSRLRQLLGEIKVIIFTIDGVFTDGQISYSESGEEVRTFHARDGFAIQEALAKGMNIAVVSERESKA
ARKRLEEIGVTDITMGVKDKMPTYEAIKARYGVSDAECVYIGDDVMDLPLFEKVGVSITPLNGVEYLRNRVYYVSGYEGG
KGCVRDVIEMVLAIQGKWKYYEM

Sequences:

>Translated_183_residues
MEIFGVSVSSEDPTSRLRQLLGEIKVIIFTIDGVFTDGQISYSESGEEVRTFHARDGFAIQEALAKGMNIAVVSERESKA
ARKRLEEIGVTDITMGVKDKMPTYEAIKARYGVSDAECVYIGDDVMDLPLFEKVGVSITPLNGVEYLRNRVYYVSGYEGG
KGCVRDVIEMVLAIQGKWKYYEM
>Mature_183_residues
MEIFGVSVSSEDPTSRLRQLLGEIKVIIFTIDGVFTDGQISYSESGEEVRTFHARDGFAIQEALAKGMNIAVVSERESKA
ARKRLEEIGVTDITMGVKDKMPTYEAIKARYGVSDAECVYIGDDVMDLPLFEKVGVSITPLNGVEYLRNRVYYVSGYEGG
KGCVRDVIEMVLAIQGKWKYYEM

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=161, Percent_Identity=24.8447204968944, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI2367202, Length=155, Percent_Identity=32.9032258064516, Blast_Score=111, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 20417; Mature: 20417

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIFGVSVSSEDPTSRLRQLLGEIKVIIFTIDGVFTDGQISYSESGEEVRTFHARDGFAI
CEEEEEECCCCCHHHHHHHHHHHHEEEEEEECCEEECCEEEECCCCCHHEEEECCCCHHH
QEALAKGMNIAVVSERESKAARKRLEEIGVTDITMGVKDKMPTYEAIKARYGVSDAECVY
HHHHHCCCEEEEEECCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHCCCCCCCEEE
IGDDVMDLPLFEKVGVSITPLNGVEYLRNRVYYVSGYEGGKGCVRDVIEMVLAIQGKWKY
ECCCCCCCCCHHHCCCEEECCCHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEE
YEM
ECC
>Mature Secondary Structure
MEIFGVSVSSEDPTSRLRQLLGEIKVIIFTIDGVFTDGQISYSESGEEVRTFHARDGFAI
CEEEEEECCCCCHHHHHHHHHHHHEEEEEEECCEEECCEEEECCCCCHHEEEECCCCHHH
QEALAKGMNIAVVSERESKAARKRLEEIGVTDITMGVKDKMPTYEAIKARYGVSDAECVY
HHHHHCCCEEEEEECCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHCCCCCCCEEE
IGDDVMDLPLFEKVGVSITPLNGVEYLRNRVYYVSGYEGGKGCVRDVIEMVLAIQGKWKY
ECCCCCCCCCHHHCCCEEECCCHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEE
YEM
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 12639950; 11835514 [H]