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The map label for this gene is msrB [H]

Identifier: 193214220

GI number: 193214220

Start: 592475

End: 593041

Strand: Direct

Name: msrB [H]

Synonym: Ctha_0501

Alternate gene names: 193214220

Gene position: 592475-593041 (Clockwise)

Preceding gene: 193214219

Following gene: 193214224

Centisome position: 17.99

GC content: 46.38

Gene sequence:

>567_bases
ATGGCTCAGACTACCAAGTATCACGCGAAATGGCTGGCCGCACTGTTTCTTCTTGGAAGCATTGCTGCGTGCCAAAGCAC
TGCGTCTCGCACTGAGGCGAGCACCGCTGATCAAGCATTTTCATGTCAAATCAAACCAGAAAATAGAGAGGATATGCCCG
ATAAAGTTATCAAAACAGATGAAGAGTGGAAATCCAAGTTGACACCGCTTCAGTTTGAAGTCACTCGCAATAAAGGAACA
GAACGCGCATTCACGGGAAAATATTACAACCATAAAGGAAAAGGGATTTACACCTGCGCTTGCTGCGGCAATGAACTTTT
CACTTCCAACGAAAAATACGATTCAGGAACAGGCTGGCCGAGTTTCTGGAAACCCGTCGATAATGACAAAATCGAAATTA
AAAAAGATTTCAGTTACGGCATGACGCGCGTTGAAGTGCTTTGCAAGCGCTGTGGCGCACATCTCGGACATGTTTTCGAA
GATGGTCCAGAGCCAACAGGCCTTCGCTACTGCATCAATTCCGTCTCGTTGGATTTCGAAGCAGCCAACGCCGAAAAAGA
AAAGTAG

Upstream 100 bases:

>100_bases
TTTAACCAGAGAGCCCATACGCGCGGAACGAACAGAACAGGTTTCGACTTTTTAAGAGAAGCTTCTCACTTTTTCTTAAA
TTTTTCATATCGTCGTAAAA

Downstream 100 bases:

>100_bases
CGTTTCTTTCGCCTTCGCCGTTTTTCCCCCTTTGCGCCAAAGCAAAAAAAGAATGCGCTTGGCCGCGATTTTCACCCCAT
GCTTTTTTGCCGAAAAATAG

Product: methionine-R-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MAQTTKYHAKWLAALFLLGSIAACQSTASRTEASTADQAFSCQIKPENREDMPDKVIKTDEEWKSKLTPLQFEVTRNKGT
ERAFTGKYYNHKGKGIYTCACCGNELFTSNEKYDSGTGWPSFWKPVDNDKIEIKKDFSYGMTRVEVLCKRCGAHLGHVFE
DGPEPTGLRYCINSVSLDFEAANAEKEK

Sequences:

>Translated_188_residues
MAQTTKYHAKWLAALFLLGSIAACQSTASRTEASTADQAFSCQIKPENREDMPDKVIKTDEEWKSKLTPLQFEVTRNKGT
ERAFTGKYYNHKGKGIYTCACCGNELFTSNEKYDSGTGWPSFWKPVDNDKIEIKKDFSYGMTRVEVLCKRCGAHLGHVFE
DGPEPTGLRYCINSVSLDFEAANAEKEK
>Mature_187_residues
AQTTKYHAKWLAALFLLGSIAACQSTASRTEASTADQAFSCQIKPENREDMPDKVIKTDEEWKSKLTPLQFEVTRNKGTE
RAFTGKYYNHKGKGIYTCACCGNELFTSNEKYDSGTGWPSFWKPVDNDKIEIKKDFSYGMTRVEVLCKRCGAHLGHVFED
GPEPTGLRYCINSVSLDFEAANAEKEK

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI37620216, Length=130, Percent_Identity=55.3846153846154, Blast_Score=166, Evalue=8e-42,
Organism=Homo sapiens, GI301336164, Length=130, Percent_Identity=55.3846153846154, Blast_Score=166, Evalue=9e-42,
Organism=Homo sapiens, GI301336162, Length=130, Percent_Identity=55.3846153846154, Blast_Score=166, Evalue=9e-42,
Organism=Homo sapiens, GI73089054, Length=130, Percent_Identity=55.3846153846154, Blast_Score=166, Evalue=9e-42,
Organism=Homo sapiens, GI117606353, Length=126, Percent_Identity=53.968253968254, Blast_Score=137, Evalue=7e-33,
Organism=Homo sapiens, GI7706511, Length=93, Percent_Identity=38.7096774193548, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1788077, Length=127, Percent_Identity=53.5433070866142, Blast_Score=146, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI17553450, Length=133, Percent_Identity=51.1278195488722, Blast_Score=123, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI115532676, Length=133, Percent_Identity=51.1278195488722, Blast_Score=123, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6319816, Length=128, Percent_Identity=42.96875, Blast_Score=109, Evalue=3e-25,
Organism=Drosophila melanogaster, GI221378664, Length=127, Percent_Identity=51.9685039370079, Blast_Score=146, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24645799, Length=131, Percent_Identity=51.1450381679389, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI45553335, Length=131, Percent_Identity=51.1450381679389, Blast_Score=144, Evalue=3e-35,
Organism=Drosophila melanogaster, GI21356369, Length=131, Percent_Identity=51.1450381679389, Blast_Score=144, Evalue=3e-35,
Organism=Drosophila melanogaster, GI221378662, Length=134, Percent_Identity=49.2537313432836, Blast_Score=144, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24645801, Length=167, Percent_Identity=42.5149700598802, Blast_Score=141, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24645804, Length=142, Percent_Identity=47.1830985915493, Blast_Score=140, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 21147; Mature: 21016

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQTTKYHAKWLAALFLLGSIAACQSTASRTEASTADQAFSCQIKPENREDMPDKVIKTD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHCCC
EEWKSKLTPLQFEVTRNKGTERAFTGKYYNHKGKGIYTCACCGNELFTSNEKYDSGTGWP
HHHHHCCCCEEEEEECCCCCCCEECCCCCCCCCCEEEEEEECCCHHHCCCCCCCCCCCCC
SFWKPVDNDKIEIKKDFSYGMTRVEVLCKRCGAHLGHVFEDGPEPTGLRYCINSVSLDFE
HHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEE
AANAEKEK
CCCCCCCC
>Mature Secondary Structure 
AQTTKYHAKWLAALFLLGSIAACQSTASRTEASTADQAFSCQIKPENREDMPDKVIKTD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHCCC
EEWKSKLTPLQFEVTRNKGTERAFTGKYYNHKGKGIYTCACCGNELFTSNEKYDSGTGWP
HHHHHCCCCEEEEEECCCCCCCEECCCCCCCCCCEEEEEEECCCHHHCCCCCCCCCCCCC
SFWKPVDNDKIEIKKDFSYGMTRVEVLCKRCGAHLGHVFEDGPEPTGLRYCINSVSLDFE
HHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEE
AANAEKEK
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]