Click here to switch to the map view.

The map label for this gene is surA [H]

Identifier: 193214213

GI number: 193214213

Start: 579881

End: 581980

Strand: Direct

Name: surA [H]

Synonym: Ctha_0494

Alternate gene names: 193214213

Gene position: 579881-581980 (Clockwise)

Preceding gene: 193214208

Following gene: 193214214

Centisome position: 17.61

GC content: 47.76

Gene sequence:

>2100_bases
ATGAACAAAATGCGCGACAGTATGCACATCGTGCTTTATGCGCTTGTCGGTGCATTTGTTTTGCTAATCGTGTTTGAATG
GGGAATGGATTTTACCGGCTTGAATCGCCGGAAAACCGATGCGGGCGTCGTTAATGGGAAACCCATTTCACTGACCGAAT
ACGACGCAACTTACCGCCGCTATCTCGACGGATTCCGCCAGCGCAGCAACAATGTCGAAATCTCCGAACAAATGGACGCA
CGCATGCGCGACCAAGCCTGGGATTTTCTCGTTTCGCAAATTTTGCTTGACGATAAATATGAAGAATTAGGGCTATTTGT
CACGGATGAAGAAATTGTCAGCGAGGTGATGTCGGACGATCCGCCGGCGATCATCGCTCAGCAATTCCGCGATCCGAAAA
CGGGCAAAATCAACACCGAAGCGCTTCAGGCGGCCATCGCGTCGCCCGAAAATAAAGAAGCCTGGATTCAGGTTGAAGAC
ATCATTCGCCAAGAGCTTCTTTTCAAAAAATTGCAAAACCTGGTCATGTCCGGCGTTTTTGTGACCGACGACGAAGCCCG
CCGCCTTTTTGATGAGCAAAATACCAAAGTTTCCGGCAGATACATTCTCTTTGAATTGGCTCACGCAAAAGCGGATTCCC
TTTACGAAATCACCGAAGCCGACATTCGCAATTACTTCAACGAACACAAAGAGGATTACAAACAAGATCCGGTTCGCGAA
GCCAATTTCGTGATGTTTTCCACTGCAGCCACCACCGAAGACACGCTTGAAATTATTCACGACCTCGAAGCGCTCAAGCC
AAAATTCCAAACCGCCAAAAACGATACGGAATTTGTAGAGCTTCAAAGCGATCGATTTGCTGATTTCGTTAAAACCTACC
GTCCTGGCAAATTGGATGCAAAGATTAGCCGACTCTTTTTTGACAATCCCTCACTGAAAGTGGGCGATGTGGTTGGGCCG
TTCCAGGAGTTTAGCGAATATAAAATTGTCAAGATTTTGGCCATCGATAGCGATGAAGATCGCCAAGCGCACGCGTCGCA
TATTTTGCTCAAGCCCGAAGGCGCTCGCCGCGCCGATACGCTGGCGGTGATGGCAGAAGCCAAACAACTGATGCGCGAGC
TGACATCAGACGAAAAGTTTGCCGAAGTTGCCCGTGAAAAATCCGACGATCCTGGCTCGGCACAAAAAGGCGGCGATCTT
GGCTGGTTTGGCAAAGGCCGGATGGTTAAGGAATTCGAAGACGCCGTGTTTCATGCAAAGCCTGGGCAGATTGTCGGGCC
AATTCAATCGCAATTTGGCATTCACATTATCAAAGTGCATGGCTTTGAAGATCGCGCGATTCGCGGCGCGGAGTTGGTTC
GCAAAATTAAAGCCGGGCCGGCAACGCTCGAGCGCGTCAATCGCCAAGCTGACGAGTTCCAGTATTTTGCCACCGAAGAA
GGATTTGAGAAAACCGCCAAGCAAGATTCAGTGGAAATTCAAAAGACAGGCGAGTTTACCAAAAACGGGTTCATTCCATC
CATTGGGTTCAATCGTTCGGTGAGCAATTTTGCTTTCCACGAGGAAGTCGGCGCGGTTAGTCCAGTCATCAGCACGCAAG
ACGCGTTTGTCATCATGCAGCTGACTGGAAAAAATGACGATGGCTACCGGAAATTAGACGAGGATTTGAAAAATACCATT
CGCGAAAAAGTGCTTCGTGAGAAAAAAATGGCAGACTTGCGAGAAAAAGCCAAAGATGTGATGGCAAAAGCGGATGGCAA
CTTGCAGAAAGCGATCGAAATTGATTCGCTTCTGACGATTCACAAAACAAACCAAGTGATGCTAACCAACGCGTTTGTTC
CGGGACTGGGCCGCGATAAAAACTTTGTTGCCGCACTTTCTGCATTGGACGAAGGGAAAGTCTCAAATCCAATCGAAACG
AAACGCGGCGTTGCCATTGCGGAATTAACAAAAAAAATCAAAGGATTCGATAGCGATTTTGAAGTGCGGAAAAATGCGTT
GAAAGATCAGATCTTGCAGGAAAAGAAAAAAGAAGTCATGAACAACTGGCTGAAAGATCTGAAAGAAAGCGCAAAAATTG
AAGATCTGCGAACAATGTAG

Upstream 100 bases:

>100_bases
TTTCAGCGCGAAAGATACGGAAATACCGATAAAAACATCCTTTCGGAAATCAGCAAAAATTAAAAAATAAAAACTACGGG
GCTTCATTGTTATGGCTATA

Downstream 100 bases:

>100_bases
CGTTCTGGTAATTGATATTTATTTTAAATTTTAGTTTTATTTAGTGGTTGCCGAAAAAAGCGTGAAACTGAATTCTCAGG
CTTTTGAGGCAGCCCTTTTT

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 699; Mature: 699

Protein sequence:

>699_residues
MNKMRDSMHIVLYALVGAFVLLIVFEWGMDFTGLNRRKTDAGVVNGKPISLTEYDATYRRYLDGFRQRSNNVEISEQMDA
RMRDQAWDFLVSQILLDDKYEELGLFVTDEEIVSEVMSDDPPAIIAQQFRDPKTGKINTEALQAAIASPENKEAWIQVED
IIRQELLFKKLQNLVMSGVFVTDDEARRLFDEQNTKVSGRYILFELAHAKADSLYEITEADIRNYFNEHKEDYKQDPVRE
ANFVMFSTAATTEDTLEIIHDLEALKPKFQTAKNDTEFVELQSDRFADFVKTYRPGKLDAKISRLFFDNPSLKVGDVVGP
FQEFSEYKIVKILAIDSDEDRQAHASHILLKPEGARRADTLAVMAEAKQLMRELTSDEKFAEVAREKSDDPGSAQKGGDL
GWFGKGRMVKEFEDAVFHAKPGQIVGPIQSQFGIHIIKVHGFEDRAIRGAELVRKIKAGPATLERVNRQADEFQYFATEE
GFEKTAKQDSVEIQKTGEFTKNGFIPSIGFNRSVSNFAFHEEVGAVSPVISTQDAFVIMQLTGKNDDGYRKLDEDLKNTI
REKVLREKKMADLREKAKDVMAKADGNLQKAIEIDSLLTIHKTNQVMLTNAFVPGLGRDKNFVAALSALDEGKVSNPIET
KRGVAIAELTKKIKGFDSDFEVRKNALKDQILQEKKKEVMNNWLKDLKESAKIEDLRTM

Sequences:

>Translated_699_residues
MNKMRDSMHIVLYALVGAFVLLIVFEWGMDFTGLNRRKTDAGVVNGKPISLTEYDATYRRYLDGFRQRSNNVEISEQMDA
RMRDQAWDFLVSQILLDDKYEELGLFVTDEEIVSEVMSDDPPAIIAQQFRDPKTGKINTEALQAAIASPENKEAWIQVED
IIRQELLFKKLQNLVMSGVFVTDDEARRLFDEQNTKVSGRYILFELAHAKADSLYEITEADIRNYFNEHKEDYKQDPVRE
ANFVMFSTAATTEDTLEIIHDLEALKPKFQTAKNDTEFVELQSDRFADFVKTYRPGKLDAKISRLFFDNPSLKVGDVVGP
FQEFSEYKIVKILAIDSDEDRQAHASHILLKPEGARRADTLAVMAEAKQLMRELTSDEKFAEVAREKSDDPGSAQKGGDL
GWFGKGRMVKEFEDAVFHAKPGQIVGPIQSQFGIHIIKVHGFEDRAIRGAELVRKIKAGPATLERVNRQADEFQYFATEE
GFEKTAKQDSVEIQKTGEFTKNGFIPSIGFNRSVSNFAFHEEVGAVSPVISTQDAFVIMQLTGKNDDGYRKLDEDLKNTI
REKVLREKKMADLREKAKDVMAKADGNLQKAIEIDSLLTIHKTNQVMLTNAFVPGLGRDKNFVAALSALDEGKVSNPIET
KRGVAIAELTKKIKGFDSDFEVRKNALKDQILQEKKKEVMNNWLKDLKESAKIEDLRTM
>Mature_699_residues
MNKMRDSMHIVLYALVGAFVLLIVFEWGMDFTGLNRRKTDAGVVNGKPISLTEYDATYRRYLDGFRQRSNNVEISEQMDA
RMRDQAWDFLVSQILLDDKYEELGLFVTDEEIVSEVMSDDPPAIIAQQFRDPKTGKINTEALQAAIASPENKEAWIQVED
IIRQELLFKKLQNLVMSGVFVTDDEARRLFDEQNTKVSGRYILFELAHAKADSLYEITEADIRNYFNEHKEDYKQDPVRE
ANFVMFSTAATTEDTLEIIHDLEALKPKFQTAKNDTEFVELQSDRFADFVKTYRPGKLDAKISRLFFDNPSLKVGDVVGP
FQEFSEYKIVKILAIDSDEDRQAHASHILLKPEGARRADTLAVMAEAKQLMRELTSDEKFAEVAREKSDDPGSAQKGGDL
GWFGKGRMVKEFEDAVFHAKPGQIVGPIQSQFGIHIIKVHGFEDRAIRGAELVRKIKAGPATLERVNRQADEFQYFATEE
GFEKTAKQDSVEIQKTGEFTKNGFIPSIGFNRSVSNFAFHEEVGAVSPVISTQDAFVIMQLTGKNDDGYRKLDEDLKNTI
REKVLREKKMADLREKAKDVMAKADGNLQKAIEIDSLLTIHKTNQVMLTNAFVPGLGRDKNFVAALSALDEGKVSNPIET
KRGVAIAELTKKIKGFDSDFEVRKNALKDQILQEKKKEVMNNWLKDLKESAKIEDLRTM

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=136, Percent_Identity=33.8235294117647, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322478, Length=105, Percent_Identity=38.0952380952381, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 79339; Mature: 79339

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKMRDSMHIVLYALVGAFVLLIVFEWGMDFTGLNRRKTDAGVVNGKPISLTEYDATYRR
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHH
YLDGFRQRSNNVEISEQMDARMRDQAWDFLVSQILLDDKYEELGLFVTDEEIVSEVMSDD
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEECHHHHHHHHCCC
PPAIIAQQFRDPKTGKINTEALQAAIASPENKEAWIQVEDIIRQELLFKKLQNLVMSGVF
CCHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCE
VTDDEARRLFDEQNTKVSGRYILFELAHAKADSLYEITEADIRNYFNEHKEDYKQDPVRE
ECCHHHHHHHHHCCCEECCCEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ANFVMFSTAATTEDTLEIIHDLEALKPKFQTAKNDTEFVELQSDRFADFVKTYRPGKLDA
CCEEEEEECCCCHHHHHHHHHHHHHCCHHHCCCCCCCEEEECHHHHHHHHHHCCCCCCHH
KISRLFFDNPSLKVGDVVGPFQEFSEYKIVKILAIDSDEDRQAHASHILLKPEGARRADT
HHHHHEECCCCCEECCCCCCHHHHCCCEEEEEEEECCCCCHHHHHCEEEECCCCCCHHHH
LAVMAEAKQLMRELTSDEKFAEVAREKSDDPGSAQKGGDLGWFGKGRMVKEFEDAVFHAK
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
PGQIVGPIQSQFGIHIIKVHGFEDRAIRGAELVRKIKAGPATLERVNRQADEFQYFATEE
CCCEECCHHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
GFEKTAKQDSVEIQKTGEFTKNGFIPSIGFNRSVSNFAFHEEVGAVSPVISTQDAFVIMQ
HHHHHHHHCCCEEHHCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEE
LTGKNDDGYRKLDEDLKNTIREKVLREKKMADLREKAKDVMAKADGNLQKAIEIDSLLTI
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEE
HKTNQVMLTNAFVPGLGRDKNFVAALSALDEGKVSNPIETKRGVAIAELTKKIKGFDSDF
ECCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHCCCCHH
EVRKNALKDQILQEKKKEVMNNWLKDLKESAKIEDLRTM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKMRDSMHIVLYALVGAFVLLIVFEWGMDFTGLNRRKTDAGVVNGKPISLTEYDATYRR
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHH
YLDGFRQRSNNVEISEQMDARMRDQAWDFLVSQILLDDKYEELGLFVTDEEIVSEVMSDD
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEECHHHHHHHHCCC
PPAIIAQQFRDPKTGKINTEALQAAIASPENKEAWIQVEDIIRQELLFKKLQNLVMSGVF
CCHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCE
VTDDEARRLFDEQNTKVSGRYILFELAHAKADSLYEITEADIRNYFNEHKEDYKQDPVRE
ECCHHHHHHHHHCCCEECCCEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ANFVMFSTAATTEDTLEIIHDLEALKPKFQTAKNDTEFVELQSDRFADFVKTYRPGKLDA
CCEEEEEECCCCHHHHHHHHHHHHHCCHHHCCCCCCCEEEECHHHHHHHHHHCCCCCCHH
KISRLFFDNPSLKVGDVVGPFQEFSEYKIVKILAIDSDEDRQAHASHILLKPEGARRADT
HHHHHEECCCCCEECCCCCCHHHHCCCEEEEEEEECCCCCHHHHHCEEEECCCCCCHHHH
LAVMAEAKQLMRELTSDEKFAEVAREKSDDPGSAQKGGDLGWFGKGRMVKEFEDAVFHAK
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
PGQIVGPIQSQFGIHIIKVHGFEDRAIRGAELVRKIKAGPATLERVNRQADEFQYFATEE
CCCEECCHHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
GFEKTAKQDSVEIQKTGEFTKNGFIPSIGFNRSVSNFAFHEEVGAVSPVISTQDAFVIMQ
HHHHHHHHCCCEEHHCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEE
LTGKNDDGYRKLDEDLKNTIREKVLREKKMADLREKAKDVMAKADGNLQKAIEIDSLLTI
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEE
HKTNQVMLTNAFVPGLGRDKNFVAALSALDEGKVSNPIETKRGVAIAELTKKIKGFDSDF
ECCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHCCCCHH
EVRKNALKDQILQEKKKEVMNNWLKDLKESAKIEDLRTM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA