BacMap

Definition	Chloroherpeton thalassium ATCC 35110 chromosome, complete genome.
Accession	NC_011026
Length	3,293,456

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The map label for this gene is fabG [H]

Identifier: 193214088

GI number: 193214088

Start: 424986

End: 425717

Strand: Direct

Name: fabG [H]

Synonym: Ctha_0369

Alternate gene names: 193214088

Gene position: 424986-425717 (Clockwise)

Preceding gene: 193214087

Following gene: 193214089

Centisome position: 12.9

GC content: 46.72

Gene sequence:

>732_bases
ATGAGCGAACTTCAGAGCGTTATCGTCAGCGGAGGAAGCAGAGGCTTAGGGCTGTCATTCGTAAAACAGTGTTTGGAAAA
AGGCGTAAAGGTCGCAACCTGTGCAAGAAAGCTGACAAACGAAATAAACGATTTGCAGCAACGCTATCCCGACCGGCTTT
TTTTTCAAGAAGTTGATATTACCGATAGCAATGCGCAAAAAAAGTTTGTCAACAGCGTTGCGTCAGCATTTGGCGAAATT
TCCGCTTTGGTAAACAATGCCGCCGTCGGTCAGGATCATTTACTGACGCACCTTCCCGAAGAAAAAATTCATCAAATTAT
AACCACCAACTTAACCTCCCAAATTCTGATGACCAAGTTGGTCGTCAAAAAAATGCTGCTTGGTGGAAATAAAGGTCGCA
TTATTAATATTTCCTCAATTTGCGGCGTAAGAGGCTATCCGGGCTTGTCGGTGTATTCAGCCACTAAAGGCGCCATGGAT
GCCTTTACGCGCTCGTTGGCACGCGAACTTGGCAATAGAGGCATTTTGGTCAACTCCATTGCGCCCGGCTTTTTCTCTTC
GGAGATGTCTCAGGTTTTAACGGAAGAGCAAATGCAAATCATCAAGCGGCGAACGGCCACTGAGGAGCTTACAACGCCCG
AGCAAATTTTGCCCGTTTTGGAAATGCTCTTGTTCACAGACAATAACATCTCAGGCCAAGTGCTTTATGTTGACGGCGGC
GCCGGCATCTGA

Upstream 100 bases:

>100_bases
ATTGCAACCGCCATGCGCTTTCTGCAAACATGATTCCGCGTTTATGGCGGTTCTTAGAGAAAATTCCGGTCGGAAAAAAT
TTTAAAAGCAAAGTATAAAG

Downstream 100 bases:

>100_bases
TTTTCACCGCATTCAAGCGCCAAAGACATGGGGCTATTGCACGATTTGCAATTCGCCGGAAGCGTTTCCGGTTCTCCTTG
CCCCCCGCGCTTACGACAAC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSELQSVIVSGGSRGLGLSFVKQCLEKGVKVATCARKLTNEINDLQQRYPDRLFFQEVDITDSNAQKKFVNSVASAFGEI
SALVNNAAVGQDHLLTHLPEEKIHQIITTNLTSQILMTKLVVKKMLLGGNKGRIINISSICGVRGYPGLSVYSATKGAMD
AFTRSLARELGNRGILVNSIAPGFFSSEMSQVLTEEQMQIIKRRTATEELTTPEQILPVLEMLLFTDNNISGQVLYVDGG
AGI

Sequences:

>Translated_243_residues
MSELQSVIVSGGSRGLGLSFVKQCLEKGVKVATCARKLTNEINDLQQRYPDRLFFQEVDITDSNAQKKFVNSVASAFGEI
SALVNNAAVGQDHLLTHLPEEKIHQIITTNLTSQILMTKLVVKKMLLGGNKGRIINISSICGVRGYPGLSVYSATKGAMD
AFTRSLARELGNRGILVNSIAPGFFSSEMSQVLTEEQMQIIKRRTATEELTTPEQILPVLEMLLFTDNNISGQVLYVDGG
AGI
>Mature_242_residues
SELQSVIVSGGSRGLGLSFVKQCLEKGVKVATCARKLTNEINDLQQRYPDRLFFQEVDITDSNAQKKFVNSVASAFGEIS
ALVNNAAVGQDHLLTHLPEEKIHQIITTNLTSQILMTKLVVKKMLLGGNKGRIINISSICGVRGYPGLSVYSATKGAMDA
FTRSLARELGNRGILVNSIAPGFFSSEMSQVLTEEQMQIIKRRTATEELTTPEQILPVLEMLLFTDNNISGQVLYVDGGA
GI

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=233, Percent_Identity=32.1888412017167, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI15277342, Length=245, Percent_Identity=30.2040816326531, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=30.859375, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI31542939, Length=251, Percent_Identity=29.4820717131474, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI7705925, Length=240, Percent_Identity=27.5, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI32483357, Length=239, Percent_Identity=27.1966527196653, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI7705855, Length=195, Percent_Identity=28.2051282051282, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI226371731, Length=190, Percent_Identity=26.8421052631579, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4758504, Length=250, Percent_Identity=24.8, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI59889578, Length=177, Percent_Identity=30.5084745762712, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI7706318, Length=186, Percent_Identity=29.5698924731183, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=27.6041666666667, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4557649, Length=195, Percent_Identity=27.1794871794872, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI44680136, Length=211, Percent_Identity=29.3838862559242, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI44680133, Length=211, Percent_Identity=29.3838862559242, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI17738292, Length=211, Percent_Identity=29.3838862559242, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI224922801, Length=166, Percent_Identity=31.3253012048193, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI109715829, Length=234, Percent_Identity=27.3504273504274, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=32.5102880658436, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=25.9109311740891, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI2367175, Length=193, Percent_Identity=33.6787564766839, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI87082160, Length=240, Percent_Identity=26.6666666666667, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1789208, Length=192, Percent_Identity=26.0416666666667, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787820, Length=188, Percent_Identity=29.2553191489362, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788459, Length=172, Percent_Identity=31.3953488372093, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=25.7261410788382, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI87082100, Length=162, Percent_Identity=30.2469135802469, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=238, Percent_Identity=26.4705882352941, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=239, Percent_Identity=26.7782426778243, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=200, Percent_Identity=27.5, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=28.5140562248996, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=25.3012048192771, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=28.8461538461538, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=30.5019305019305, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=25.8687258687259, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=25.8196721311475, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=255, Percent_Identity=30.9803921568627, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=236, Percent_Identity=26.6949152542373, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=28.030303030303, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=255, Percent_Identity=27.843137254902, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=254, Percent_Identity=26.7716535433071, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=27.027027027027, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17507613, Length=200, Percent_Identity=28.5, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=200, Percent_Identity=28.5, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI72001658, Length=208, Percent_Identity=29.3269230769231, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=222, Percent_Identity=28.8288288288288, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=257, Percent_Identity=26.4591439688716, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=187, Percent_Identity=27.807486631016, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=204, Percent_Identity=27.9411764705882, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=24.8091603053435, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=195, Percent_Identity=27.6923076923077, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=188, Percent_Identity=28.7234042553192, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=26.1538461538462, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=191, Percent_Identity=29.3193717277487, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=214, Percent_Identity=33.6448598130841, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322795, Length=213, Percent_Identity=29.1079812206573, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322227, Length=247, Percent_Identity=23.8866396761134, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322226, Length=186, Percent_Identity=26.3440860215054, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI23397609, Length=242, Percent_Identity=28.5123966942149, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21357041, Length=189, Percent_Identity=29.6296296296296, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24639444, Length=236, Percent_Identity=28.3898305084746, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571526, Length=244, Percent_Identity=26.6393442622951, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=25.5060728744939, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=27.4611398963731, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24640442, Length=196, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24643142, Length=183, Percent_Identity=30.6010928961749, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21356301, Length=200, Percent_Identity=28, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28571387, Length=194, Percent_Identity=28.8659793814433, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007236, Length=195, Percent_Identity=26.1538461538462, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17737361, Length=247, Percent_Identity=23.8866396761134, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21355319, Length=239, Percent_Identity=25.9414225941423, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24644337, Length=117, Percent_Identity=34.1880341880342, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24665264, Length=185, Percent_Identity=27.027027027027, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641232, Length=196, Percent_Identity=26.530612244898, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574402, Length=202, Percent_Identity=22.7722772277228, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24584744, Length=202, Percent_Identity=22.7722772277228, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24580925, Length=198, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24651139, Length=212, Percent_Identity=27.8301886792453, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584748, Length=187, Percent_Identity=23.5294117647059, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161076933, Length=187, Percent_Identity=23.5294117647059, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24665268, Length=207, Percent_Identity=24.1545893719807, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24649181, Length=193, Percent_Identity=26.9430051813472, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI116007238, Length=174, Percent_Identity=25.8620689655172, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26449; Mature: 26318

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELQSVIVSGGSRGLGLSFVKQCLEKGVKVATCARKLTNEINDLQQRYPDRLFFQEVDI
CHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
TDSNAQKKFVNSVASAFGEISALVNNAAVGQDHLLTHLPEEKIHQIITTNLTSQILMTKL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VVKKMLLGGNKGRIINISSICGVRGYPGLSVYSATKGAMDAFTRSLARELGNRGILVNSI
HHHHHHHCCCCCCEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
APGFFSSEMSQVLTEEQMQIIKRRTATEELTTPEQILPVLEMLLFTDNNISGQVLYVDGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEECCC
AGI
CCC
>Mature Secondary Structure 
SELQSVIVSGGSRGLGLSFVKQCLEKGVKVATCARKLTNEINDLQQRYPDRLFFQEVDI
HHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
TDSNAQKKFVNSVASAFGEISALVNNAAVGQDHLLTHLPEEKIHQIITTNLTSQILMTKL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VVKKMLLGGNKGRIINISSICGVRGYPGLSVYSATKGAMDAFTRSLARELGNRGILVNSI
HHHHHHHCCCCCCEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
APGFFSSEMSQVLTEEQMQIIKRRTATEELTTPEQILPVLEMLLFTDNNISGQVLYVDGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEECCC
AGI
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]