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The map label for this gene is yciA [C]

Identifier: 193214038

GI number: 193214038

Start: 366450

End: 366929

Strand: Direct

Name: yciA [C]

Synonym: Ctha_0319

Alternate gene names: 193214038

Gene position: 366450-366929 (Clockwise)

Preceding gene: 193214029

Following gene: 193214040

Centisome position: 11.13

GC content: 52.92

Gene sequence:

>480_bases
ATGTCAGAAAAAACGCGTCCGGCAAAACCGGTATCGGCTTCTCGCGTGGAGACGACGCATTTTGTGACCCCTCCCGACGT
GAATTATCTTGGAAATTTGGCTGGTGGAAAACTCATGCACTGGATGGACTTGACCGCAGCCATTGCAGCCGGGCGCCACG
CCAACGCGGTTTCCGTCACGGCCTCCGTCGATTCGCTCGACTTCAAACATCCGATCAATCTTGGCGAAGTGGTGATTATT
AAGGCGAGCGTCAATCGCGCGTTCAATTCGTCGATGGAAGTGGGCGTGAAGGTGATTTCGGAGAATCTGATTACTGGCGA
GCAAAAGGTTTGCAATCGGGCTTATTTTACGTTCGTTGCCATCGACGATTCCCTTTCACCAACAAGCGTTCCCGCCGTTC
TGCCCGAAACGGAAGAAGAAAAACAGCGCTACAACAAAGCCGAACTCCGCCGGCAAATTCGCCTGCTCAACAAGGGATGA

Upstream 100 bases:

>100_bases
TTGCATTTAAAGTCGCTCAGCGCTCACTGTTTTTTTACTGCCATTTATCGGTTATCTTTTGATAAAAACAATTCTTAACA
GCCACAAACGTATCATTCCT

Downstream 100 bases:

>100_bases
ATCAAGCGCGCTCGCCAATTCTAACGCGAACGGAACATGCTATTCCCCAAAAAAAAGGGCGAGCCCAACAGCTCGCCCAC
TTTTGAGATCGTATCAAACG

Product: thioesterase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MSEKTRPAKPVSASRVETTHFVTPPDVNYLGNLAGGKLMHWMDLTAAIAAGRHANAVSVTASVDSLDFKHPINLGEVVII
KASVNRAFNSSMEVGVKVISENLITGEQKVCNRAYFTFVAIDDSLSPTSVPAVLPETEEEKQRYNKAELRRQIRLLNKG

Sequences:

>Translated_159_residues
MSEKTRPAKPVSASRVETTHFVTPPDVNYLGNLAGGKLMHWMDLTAAIAAGRHANAVSVTASVDSLDFKHPINLGEVVII
KASVNRAFNSSMEVGVKVISENLITGEQKVCNRAYFTFVAIDDSLSPTSVPAVLPETEEEKQRYNKAELRRQIRLLNKG
>Mature_158_residues
SEKTRPAKPVSASRVETTHFVTPPDVNYLGNLAGGKLMHWMDLTAAIAAGRHANAVSVTASVDSLDFKHPINLGEVVIIK
ASVNRAFNSSMEVGVKVISENLITGEQKVCNRAYFTFVAIDDSLSPTSVPAVLPETEEEKQRYNKAELRRQIRLLNKG

Specific function: Unknown

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI22165355, Length=143, Percent_Identity=44.0559440559441, Blast_Score=120, Evalue=5e-28,
Organism=Homo sapiens, GI22165400, Length=143, Percent_Identity=44.0559440559441, Blast_Score=120, Evalue=6e-28,
Organism=Homo sapiens, GI18640736, Length=134, Percent_Identity=38.0597014925373, Blast_Score=100, Evalue=5e-22,
Organism=Homo sapiens, GI32528282, Length=142, Percent_Identity=35.9154929577465, Blast_Score=87, Evalue=9e-18,
Organism=Homo sapiens, GI32528284, Length=142, Percent_Identity=35.9154929577465, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI32528286, Length=142, Percent_Identity=35.9154929577465, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI75709208, Length=142, Percent_Identity=35.9154929577465, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 17392; Mature: 17261

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKTRPAKPVSASRVETTHFVTPPDVNYLGNLAGGKLMHWMDLTAAIAAGRHANAVSVT
CCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEE
ASVDSLDFKHPINLGEVVIIKASVNRAFNSSMEVGVKVISENLITGEQKVCNRAYFTFVA
EECCCCCCCCCCCCCCEEEEEECCCCHHCCHHHHHHHHHHHHHCCCHHHHHCCEEEEEEE
IDDSLSPTSVPAVLPETEEEKQRYNKAELRRQIRLLNKG
ECCCCCCCCCCEECCCCHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEKTRPAKPVSASRVETTHFVTPPDVNYLGNLAGGKLMHWMDLTAAIAAGRHANAVSVT
CCCCCCCCCCCCCCCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEE
ASVDSLDFKHPINLGEVVIIKASVNRAFNSSMEVGVKVISENLITGEQKVCNRAYFTFVA
EECCCCCCCCCCCCCCEEEEEECCCCHHCCHHHHHHHHHHHHHCCCHHHHHCCEEEEEEE
IDDSLSPTSVPAVLPETEEEKQRYNKAELRRQIRLLNKG
ECCCCCCCCCCEECCCCHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]