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The map label for this gene is purQ [H]

Identifier: 193213929

GI number: 193213929

Start: 244955

End: 245662

Strand: Direct

Name: purQ [H]

Synonym: Ctha_0210

Alternate gene names: 193213929

Gene position: 244955-245662 (Clockwise)

Preceding gene: 193213928

Following gene: 193213930

Centisome position: 7.44

GC content: 47.03

Gene sequence:

>708_bases
ATGGCAAAAACAAAATTCGGTATTGTCGTTTTTCCAGGTTCTAATTGCGATCACGATACAGAATATGTGTGTAACGCTTT
TCCAAATGCTGAAGCGAAATTGATTTGGCACCAGGAAAGCGATTTACAAGGTGCTGATGTGATCGTTTTGCCAGGCGGAT
TTTCCTATGGCGATTATCTTCGTGCGGGCGCTATCGCGAAGTTTTCTCCTGTGATGCAAGAAGTAATTCGGTTTGCAGGC
GAAGGCCGACCTGTTATTGGCATTTGCAATGGGTTTCAGGTGCTTTTGGAAAGCGGCTTGCTCGAAGGCGCTATGATGCA
CAACAAAAGCCGTCGGTTTATCTGCAAATTTGTATACCTGAAAGTCGCAAACAATCAAACGCTTTTTACCAGCAAATACG
AGAAAGACGCCGTCGTGCGGATTCCCATTGCACACGGCGAGGGCAATTTCTTTGCGTCGGAGGCAACGCTAAGCCGGTTG
CAGGAAAATGAGCAGATTGTATTTCAATATTGCGACAAAGCGGGACAGCTCAGCGAGGCGGCCAACCCGAACGGCTCGTG
CCTCAATATCGCTGGAATTGTCAATGAAAAAAGAAACGTGCTCGGCATGATGCCGCACCCCGAACGCGCTTCGGATGCGA
TGCTGGGCTCAACAGATGGAAGCAAAGTTTTTGAGTCCATTTTAAATAATTTTGTTGAAGCCGTTTAA

Upstream 100 bases:

>100_bases
TTATGGAAGATTATAGCTACGATCTTGAAACGATCTAAATGCATAGCAATCAACAAGGCAAATAACTTTTTAACCAATTG
TATTCTTAAGTTTTTTACTA

Downstream 100 bases:

>100_bases
TCGGTTTTTGCTGGTGGAGACGAAGGCTGCATCAACATTTCACTTGTCAATTTATCTCAAAAGATTTATTGAAAGTGAAA
AAAAATGCCAACCGTTCGTC

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MAKTKFGIVVFPGSNCDHDTEYVCNAFPNAEAKLIWHQESDLQGADVIVLPGGFSYGDYLRAGAIAKFSPVMQEVIRFAG
EGRPVIGICNGFQVLLESGLLEGAMMHNKSRRFICKFVYLKVANNQTLFTSKYEKDAVVRIPIAHGEGNFFASEATLSRL
QENEQIVFQYCDKAGQLSEAANPNGSCLNIAGIVNEKRNVLGMMPHPERASDAMLGSTDGSKVFESILNNFVEAV

Sequences:

>Translated_235_residues
MAKTKFGIVVFPGSNCDHDTEYVCNAFPNAEAKLIWHQESDLQGADVIVLPGGFSYGDYLRAGAIAKFSPVMQEVIRFAG
EGRPVIGICNGFQVLLESGLLEGAMMHNKSRRFICKFVYLKVANNQTLFTSKYEKDAVVRIPIAHGEGNFFASEATLSRL
QENEQIVFQYCDKAGQLSEAANPNGSCLNIAGIVNEKRNVLGMMPHPERASDAMLGSTDGSKVFESILNNFVEAV
>Mature_234_residues
AKTKFGIVVFPGSNCDHDTEYVCNAFPNAEAKLIWHQESDLQGADVIVLPGGFSYGDYLRAGAIAKFSPVMQEVIRFAGE
GRPVIGICNGFQVLLESGLLEGAMMHNKSRRFICKFVYLKVANNQTLFTSKYEKDAVVRIPIAHGEGNFFASEATLSRLQ
ENEQIVFQYCDKAGQLSEAANPNGSCLNIAGIVNEKRNVLGMMPHPERASDAMLGSTDGSKVFESILNNFVEAV

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=183, Percent_Identity=31.1475409836066, Blast_Score=75, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321498, Length=180, Percent_Identity=32.7777777777778, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24582111, Length=184, Percent_Identity=34.7826086956522, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24582109, Length=184, Percent_Identity=34.7826086956522, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17137292, Length=184, Percent_Identity=34.7826086956522, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 25708; Mature: 25576

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTKFGIVVFPGSNCDHDTEYVCNAFPNAEAKLIWHQESDLQGADVIVLPGGFSYGDYL
CCCCEEEEEEECCCCCCCCHHHHHHCCCCCCEEEEEECCCCCCCCCEEEECCCCCHHHHH
RAGAIAKFSPVMQEVIRFAGEGRPVIGICNGFQVLLESGLLEGAMMHNKSRRFICKFVYL
HHCCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHCCHHHHHHHCCCHHEEEEEEEE
KVANNQTLFTSKYEKDAVVRIPIAHGEGNFFASEATLSRLQENEQIVFQYCDKAGQLSEA
EECCCCEEEEECCCCCCEEEEEEEECCCCEEEHHHHHHHHHCCHHHHHHHHHHCCCHHHC
ANPNGSCLNIAGIVNEKRNVLGMMPHPERASDAMLGSTDGSKVFESILNNFVEAV
CCCCCCEEEEEEECCCCCCEEECCCCCCCCCCCEECCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKTKFGIVVFPGSNCDHDTEYVCNAFPNAEAKLIWHQESDLQGADVIVLPGGFSYGDYL
CCCEEEEEEECCCCCCCCHHHHHHCCCCCCEEEEEECCCCCCCCCEEEECCCCCHHHHH
RAGAIAKFSPVMQEVIRFAGEGRPVIGICNGFQVLLESGLLEGAMMHNKSRRFICKFVYL
HHCCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHCCHHHHHHHCCCHHEEEEEEEE
KVANNQTLFTSKYEKDAVVRIPIAHGEGNFFASEATLSRLQENEQIVFQYCDKAGQLSEA
EECCCCEEEEECCCCCCEEEEEEEECCCCEEEHHHHHHHHHCCHHHHHHHHHHCCCHHHC
ANPNGSCLNIAGIVNEKRNVLGMMPHPERASDAMLGSTDGSKVFESILNNFVEAV
CCCCCCEEEEEEECCCCCCEEECCCCCCCCCCCEECCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA