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The map label for this gene is mrdB [H]

Identifier: 193213836

GI number: 193213836

Start: 137456

End: 138688

Strand: Direct

Name: mrdB [H]

Synonym: Ctha_0117

Alternate gene names: 193213836

Gene position: 137456-138688 (Clockwise)

Preceding gene: 193213834

Following gene: 193213837

Centisome position: 4.17

GC content: 44.93

Gene sequence:

>1233_bases
ATGCGCGAAATAAAGTTATTTGCACAAATAGATCTCACCTTGCTTCTGTCCATGCTCGGGCTGATTGTTTTTGGCTTGAT
GGCCATTTATAGTGCCAGCCACGGCGTTGGCGTCATGGGAAATTATTACAAGCAACTGGTTTGGTTCGGCCTCAGCTTTT
TCCTTCTGATTATTATTTTCTACATGCCGCCGCGCATTTTTCAAGACTACGCCTACTGGATTTATGGCCTTTCCATCACG
GGACTTGTGCTTGTATTGCTGCTTGGCAGAAAAGTCGGTGGCGCCACCAGTTGGATCGACATTGGCTTTGCGCGCATTCA
GCCGTCCGAGTTTACGAAATACTCTACCATCCTGGCACTGGCGCGTTTTCTTTCGGAGCGAACAACAAATATAAAAACCC
TTCGACATTTTACCACCGCAATCGGCATTGCGGTTTTTCCCGTCATTTTAGTTTTGCTTCAACCCGACACAGGAACAGCG
CTCACCTATTTAACATTCATTGTTCCGATGATTGTTATCGCCGGATTTGATTTTTACATCATCGTGCTAATGGCCATTCC
GTTTGTGTTTGCATTGGTTGGATTTATCAACCTCTACGCGCTGGTGGTTCTGGGTTTTGTGATGATGGGATTTCTCATTT
TAATGAGAAAAGAAGCCATATTTCTTTCAATTGGAGCGCTCGCCATCGGGGTTATGTTTGGTGTTTTTTCGAGCTTTTAT
GGAAAAAGCATTTTGCAGCCGCATCAGTTAAAGCGCATTGAAACCTTTCTCGATCCCATGTCCGATCCGAAAGGCGCAGG
CTACAACGCTCTTCAAGCAAAAGTGGCAATCGGCTCGGGCGGACTTTGGGGAAAAGGTTTTTTAGAAGGAACGCAAACGC
AGCTTCGCTTTATTCCGGCGCAATGGACGGATTTTATTTTCTGCGTTATCGGTGAAGAATTTGGGTTTATTGGCTCGACA
GTGCTTTTAACGACGTTTTTGATTTTCATCACGCGCTTGGTCATGTTGATTCACATCATCAAAAACGAGTTTGCAGCTCT
GGTGATTTCAGGGATTGTTTCCGTATTTTTTGGCCACATTTTAGTCAACATTGGAATGACAATTGGGCTGATGCCGATTG
TGGGCGTTCCCTTGCCATTTCTTTCATATGGCGGGTCATCGCTTTTGGCAAACATGGTTGCGGTTGCCATTGTTCTAAAT
TTTTACCGAAACCGCAGAGATTTGGCTTTATAG

Upstream 100 bases:

>100_bases
GGGTTTCTTCTTCATTCATTTTGGTCAAACTTGAACATTGTTTTGCTATAAACAGCCTGTATATTTATTCCTTTTATGAA
AATAACACGTCCGATTTAGA

Downstream 100 bases:

>100_bases
TAGCAGTATGAAAACATCTTTTGGGGCGTATGCCGCCATGCTTGGGCAAACGGTGCTGGCCGGCCTGAGCTTTGCCTTTG
CACGAGACGCTTCCGTTGAA

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MREIKLFAQIDLTLLLSMLGLIVFGLMAIYSASHGVGVMGNYYKQLVWFGLSFFLLIIIFYMPPRIFQDYAYWIYGLSIT
GLVLVLLLGRKVGGATSWIDIGFARIQPSEFTKYSTILALARFLSERTTNIKTLRHFTTAIGIAVFPVILVLLQPDTGTA
LTYLTFIVPMIVIAGFDFYIIVLMAIPFVFALVGFINLYALVVLGFVMMGFLILMRKEAIFLSIGALAIGVMFGVFSSFY
GKSILQPHQLKRIETFLDPMSDPKGAGYNALQAKVAIGSGGLWGKGFLEGTQTQLRFIPAQWTDFIFCVIGEEFGFIGST
VLLTTFLIFITRLVMLIHIIKNEFAALVISGIVSVFFGHILVNIGMTIGLMPIVGVPLPFLSYGGSSLLANMVAVAIVLN
FYRNRRDLAL

Sequences:

>Translated_410_residues
MREIKLFAQIDLTLLLSMLGLIVFGLMAIYSASHGVGVMGNYYKQLVWFGLSFFLLIIIFYMPPRIFQDYAYWIYGLSIT
GLVLVLLLGRKVGGATSWIDIGFARIQPSEFTKYSTILALARFLSERTTNIKTLRHFTTAIGIAVFPVILVLLQPDTGTA
LTYLTFIVPMIVIAGFDFYIIVLMAIPFVFALVGFINLYALVVLGFVMMGFLILMRKEAIFLSIGALAIGVMFGVFSSFY
GKSILQPHQLKRIETFLDPMSDPKGAGYNALQAKVAIGSGGLWGKGFLEGTQTQLRFIPAQWTDFIFCVIGEEFGFIGST
VLLTTFLIFITRLVMLIHIIKNEFAALVISGIVSVFFGHILVNIGMTIGLMPIVGVPLPFLSYGGSSLLANMVAVAIVLN
FYRNRRDLAL
>Mature_410_residues
MREIKLFAQIDLTLLLSMLGLIVFGLMAIYSASHGVGVMGNYYKQLVWFGLSFFLLIIIFYMPPRIFQDYAYWIYGLSIT
GLVLVLLLGRKVGGATSWIDIGFARIQPSEFTKYSTILALARFLSERTTNIKTLRHFTTAIGIAVFPVILVLLQPDTGTA
LTYLTFIVPMIVIAGFDFYIIVLMAIPFVFALVGFINLYALVVLGFVMMGFLILMRKEAIFLSIGALAIGVMFGVFSSFY
GKSILQPHQLKRIETFLDPMSDPKGAGYNALQAKVAIGSGGLWGKGFLEGTQTQLRFIPAQWTDFIFCVIGEEFGFIGST
VLLTTFLIFITRLVMLIHIIKNEFAALVISGIVSVFFGHILVNIGMTIGLMPIVGVPLPFLSYGGSSLLANMVAVAIVLN
FYRNRRDLAL

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=406, Percent_Identity=32.7586206896552, Blast_Score=188, Evalue=7e-49,
Organism=Escherichia coli, GI1786277, Length=411, Percent_Identity=30.4136253041363, Blast_Score=156, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 45360; Mature: 45360

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS00228 TUBULIN_B_AUTOREG ; PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]