Click here to switch to the map view.

The map label for this gene is ppnK

Identifier: 193213629

GI number: 193213629

Start: 2192952

End: 2193803

Strand: Direct

Name: ppnK

Synonym: Cpar_1993

Alternate gene names: 193213629

Gene position: 2192952-2193803 (Clockwise)

Preceding gene: 193213628

Following gene: 193213630

Centisome position: 95.79

GC content: 58.1

Gene sequence:

>852_bases
ATGAAACTGGCCATCATCGTCAACATCACGCGCGACAAGGCGCTGGAACTGGCATGCGAACTTGTCGCCTGGCTGGATGA
GCGTTCGATCGACTACGTGTTCGATCGCCAGTCGGCCAAAGCTATCGGCAGCGGCAAGTGGGAAGAGAAGGCTGACCTCA
ACCAGCACTGCGACGCCTTCGTCTCCCTTGGTGGTGACGGCACGCTGCTGCTCGCCTCGCACTACTCCCGCTCCAAACCC
GTGCTCGGCATCAACGTGGGCGACCTCGGCTTTTTGACCGAGTTCAGTCCCGACGAGATGTGGACGGCGATGGAGCATCT
GGTCAGCGGAAATTATTCAAAGCATACCCGCTCGCAGCTCGAAGCAACGCTTGAATCGGAAGAACCGATGACAGCACTCA
ACGACGTCATCATTGAAAAGGGCACGGCAACACGACGGCTGCCGGCGTTCGTCATCCGGCTGGACGACGAAATTCTCGGC
TCCTACCGCGCCGACGGCATCGTCATCGCAACCTCGACCGGCTCGACGGCCTACTCGCTCTCCGCAGGTGGCCCGATCAT
CGCGCCGAAGTCGAACGTGTTCGTCATCACGCCGATCTGCCCGCACATGCTGACCGTGCGGCCAATTGTCATCAGCGACG
ACAAAACCATCAAGGTTTCGGTCGATTCACAATCCGGAGAGTTTCCGCTGAAAATGGACGGCATCCAGAAAAAACTGCTC
GCTCCGGGAGAGGTGGTGACGGTCAAAAAGTCGCCGCATCACGTCAATCTGGTGGCCAATCAGAAAAGAAGCTACTGCGA
AATCCTTCGCAAAAAGCTGCTCTGGAGCCACGAACACCCCACAGGCCAGTAA

Upstream 100 bases:

>100_bases
ACCTCGCCGAAGAGGTGCGCAACGACAATATCGAGGCACTCGATGCGAGGTTCCGGGAAGCGAACGAGCTCTATCAACGC
CTTCAGGAAAGGGGCTGCTC

Downstream 100 bases:

>100_bases
CCGCACCGAGACCATTGACAAACCCACGAGCCTCTGTTTTTCATGACTGAACGCATCAGCGCCTTCTGGCTGAACCGGCT
TCTCGGCATTCCAACCTCAA

Product: ATP-NAD/AcoX kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MKLAIIVNITRDKALELACELVAWLDERSIDYVFDRQSAKAIGSGKWEEKADLNQHCDAFVSLGGDGTLLLASHYSRSKP
VLGINVGDLGFLTEFSPDEMWTAMEHLVSGNYSKHTRSQLEATLESEEPMTALNDVIIEKGTATRRLPAFVIRLDDEILG
SYRADGIVIATSTGSTAYSLSAGGPIIAPKSNVFVITPICPHMLTVRPIVISDDKTIKVSVDSQSGEFPLKMDGIQKKLL
APGEVVTVKKSPHHVNLVANQKRSYCEILRKKLLWSHEHPTGQ

Sequences:

>Translated_283_residues
MKLAIIVNITRDKALELACELVAWLDERSIDYVFDRQSAKAIGSGKWEEKADLNQHCDAFVSLGGDGTLLLASHYSRSKP
VLGINVGDLGFLTEFSPDEMWTAMEHLVSGNYSKHTRSQLEATLESEEPMTALNDVIIEKGTATRRLPAFVIRLDDEILG
SYRADGIVIATSTGSTAYSLSAGGPIIAPKSNVFVITPICPHMLTVRPIVISDDKTIKVSVDSQSGEFPLKMDGIQKKLL
APGEVVTVKKSPHHVNLVANQKRSYCEILRKKLLWSHEHPTGQ
>Mature_283_residues
MKLAIIVNITRDKALELACELVAWLDERSIDYVFDRQSAKAIGSGKWEEKADLNQHCDAFVSLGGDGTLLLASHYSRSKP
VLGINVGDLGFLTEFSPDEMWTAMEHLVSGNYSKHTRSQLEATLESEEPMTALNDVIIEKGTATRRLPAFVIRLDDEILG
SYRADGIVIATSTGSTAYSLSAGGPIIAPKSNVFVITPICPHMLTVRPIVISDDKTIKVSVDSQSGEFPLKMDGIQKKLL
APGEVVTVKKSPHHVNLVANQKRSYCEILRKKLLWSHEHPTGQ

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family

Homologues:

Organism=Homo sapiens, GI55743112, Length=237, Percent_Identity=28.2700421940928, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1788968, Length=264, Percent_Identity=32.9545454545455, Blast_Score=144, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6320794, Length=317, Percent_Identity=29.6529968454259, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6322509, Length=242, Percent_Identity=31.8181818181818, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6325068, Length=213, Percent_Identity=33.8028169014084, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28573830, Length=239, Percent_Identity=32.2175732217573, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28573826, Length=239, Percent_Identity=32.2175732217573, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28573828, Length=239, Percent_Identity=32.2175732217573, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI161077047, Length=239, Percent_Identity=32.2175732217573, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28573832, Length=239, Percent_Identity=32.2175732217573, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24653422, Length=279, Percent_Identity=26.8817204301075, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI20129957, Length=279, Percent_Identity=26.8817204301075, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281363323, Length=279, Percent_Identity=26.8817204301075, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24653424, Length=279, Percent_Identity=26.8817204301075, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281363321, Length=279, Percent_Identity=26.8817204301075, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPNK_CHLP8 (B3QLE4)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001999582.1
- ProteinModelPortal:   B3QLE4
- GeneID:   6420945
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_1993
- HOGENOM:   HBG713904
- OMA:   VANEKRN
- ProtClustDB:   CLSK637151
- GO:   GO:0005737
- HAMAP:   MF_00361
- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504
- Gene3D:   G3DSA:2.60.200.30
- Gene3D:   G3DSA:3.40.50.10330
- PANTHER:   PTHR20275

Pfam domain/function: PF01513 NAD_kinase; SSF111331 ATP-NAD_kinase_PpnK-typ

EC number: =2.7.1.23

Molecular weight: Translated: 31081; Mature: 31081

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAIIVNITRDKALELACELVAWLDERSIDYVFDRQSAKAIGSGKWEEKADLNQHCDAF
CEEEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHCCCCCCCCCCHHHHHHEE
VSLGGDGTLLLASHYSRSKPVLGINVGDLGFLTEFSPDEMWTAMEHLVSGNYSKHTRSQL
EEECCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
EATLESEEPMTALNDVIIEKGTATRRLPAFVIRLDDEILGSYRADGIVIATSTGSTAYSL
HHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEEEECHHHHCCCCCCCEEEEECCCCCEEEE
SAGGPIIAPKSNVFVITPICPHMLTVRPIVISDDKTIKVSVDSQSGEFPLKMDGIQKKLL
CCCCCEECCCCCEEEECCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCEEECCHHHHHC
APGEVVTVKKSPHHVNLVANQKRSYCEILRKKLLWSHEHPTGQ
CCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKLAIIVNITRDKALELACELVAWLDERSIDYVFDRQSAKAIGSGKWEEKADLNQHCDAF
CEEEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHCCCCCCCCCCHHHHHHEE
VSLGGDGTLLLASHYSRSKPVLGINVGDLGFLTEFSPDEMWTAMEHLVSGNYSKHTRSQL
EEECCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
EATLESEEPMTALNDVIIEKGTATRRLPAFVIRLDDEILGSYRADGIVIATSTGSTAYSL
HHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEEEECHHHHCCCCCCCEEEEECCCCCEEEE
SAGGPIIAPKSNVFVITPICPHMLTVRPIVISDDKTIKVSVDSQSGEFPLKMDGIQKKLL
CCCCCEECCCCCEEEECCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCEEECCHHHHHC
APGEVVTVKKSPHHVNLVANQKRSYCEILRKKLLWSHEHPTGQ
CCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA