Click here to switch to the map view.

The map label for this gene is gap [H]

Identifier: 193213215

GI number: 193213215

Start: 1719244

End: 1720248

Strand: Direct

Name: gap [H]

Synonym: Cpar_1570

Alternate gene names: 193213215

Gene position: 1719244-1720248 (Clockwise)

Preceding gene: 193213214

Following gene: 193213216

Centisome position: 75.1

GC content: 57.51

Gene sequence:

>1005_bases
ATGGCGAAAGTTAAAGTTGGCATCAATGGTTTTGGCCGCATCGGCCGTCTGGTATTCAGACAGGCTGTGGACAATCCCGA
CGTCGAAATCGTCGGTATCAACGACCTCACCGATGTAAATACCCTTGCTCACCTCCTCAAATACGACAGCACCCACAAAA
AATTCAATGGTGAAGTGAAGGTCGAGGGCGACAACCTGGTCGTCAACGGTAAAACCATCGCCATCTGCGCCCAGAGAGAT
CCTGCAGAGCTTCCATGGAAGTCGCTCGGCGCTGAGCTCGTAGTCGAGTCCACCGGCATTTTCACCAAGCGTGAAGCCGC
GGCCAAGCACATCGCTGCCGGCGCCAAAAAGGTGATTATCTCGGCTCCCGCCAAGGACAAGGTCGACGCCACCATCGTCA
TGGGCGTCAATGACGATTGCATCACTGGCAACGAGGAGATCGTCTCCAACGCAAGCTGCACCACCAACTGCCTCGCCCCG
ATGGTGAAAGTGCTCCACGAGAACTTCGGCATCGTCAAGGGCTTCATGACCACCGTGCACGCCTACACCAACGACCAGAA
CATCCTCGACCTTCCGCACAAGGATCTGCGTCGTGCCCGCTCGGCAGCCAACTCGATCATTCCGACCTCGACCGGCGCCG
CAAAAGCGATCGGTGAAGTGCTGCCCGAACTGGCAGGCAAGCTCGACGGTTTCGCCATGAGGGTTCCGGTTCCGGACGGT
TCGGTTACCGACCTTTCGGTCATCGTTGAAAAAGAGGCCACCAAGGAAGCGATCAACGCTGCCATGAAAGCTGCCGCCGA
AGGCCCGATGAAGGGCATCCTCGAGTACAACGTCGATCCGATCGTCTCCTGCGACATCGTCGGCAACGCTCACTCCTGCA
TCTTCGACTCGCCGCTCACCATGAGCTCCGGCAACCTGATCAAGGTGGTCGGCTGGTACGACAACGAGCTTGGCTATGCA
ACCCGCGTGGTTGACCTGCTCAGCATCTACTCGAAGTTCGTCTGA

Upstream 100 bases:

>100_bases
TGTGACTTTTCCTGGGCGGCGCATGCCCGGTTCATGCCGCTGCAACCATCCCGAACAGAGTCATTATCATATCCGTTAAA
CCCATAGAGAAAGACCCGTT

Downstream 100 bases:

>100_bases
TTTCTACACGAACAGATGACCATCAAAAGGGCGCCCGCAACGGCGCCCTTTTGCATTTGTGGGGAGATGGTGGCTGATCT
AAAGAGGGCAGACACGCAGG

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MAKVKVGINGFGRIGRLVFRQAVDNPDVEIVGINDLTDVNTLAHLLKYDSTHKKFNGEVKVEGDNLVVNGKTIAICAQRD
PAELPWKSLGAELVVESTGIFTKREAAAKHIAAGAKKVIISAPAKDKVDATIVMGVNDDCITGNEEIVSNASCTTNCLAP
MVKVLHENFGIVKGFMTTVHAYTNDQNILDLPHKDLRRARSAANSIIPTSTGAAKAIGEVLPELAGKLDGFAMRVPVPDG
SVTDLSVIVEKEATKEAINAAMKAAAEGPMKGILEYNVDPIVSCDIVGNAHSCIFDSPLTMSSGNLIKVVGWYDNELGYA
TRVVDLLSIYSKFV

Sequences:

>Translated_334_residues
MAKVKVGINGFGRIGRLVFRQAVDNPDVEIVGINDLTDVNTLAHLLKYDSTHKKFNGEVKVEGDNLVVNGKTIAICAQRD
PAELPWKSLGAELVVESTGIFTKREAAAKHIAAGAKKVIISAPAKDKVDATIVMGVNDDCITGNEEIVSNASCTTNCLAP
MVKVLHENFGIVKGFMTTVHAYTNDQNILDLPHKDLRRARSAANSIIPTSTGAAKAIGEVLPELAGKLDGFAMRVPVPDG
SVTDLSVIVEKEATKEAINAAMKAAAEGPMKGILEYNVDPIVSCDIVGNAHSCIFDSPLTMSSGNLIKVVGWYDNELGYA
TRVVDLLSIYSKFV
>Mature_333_residues
AKVKVGINGFGRIGRLVFRQAVDNPDVEIVGINDLTDVNTLAHLLKYDSTHKKFNGEVKVEGDNLVVNGKTIAICAQRDP
AELPWKSLGAELVVESTGIFTKREAAAKHIAAGAKKVIISAPAKDKVDATIVMGVNDDCITGNEEIVSNASCTTNCLAPM
VKVLHENFGIVKGFMTTVHAYTNDQNILDLPHKDLRRARSAANSIIPTSTGAAKAIGEVLPELAGKLDGFAMRVPVPDGS
VTDLSVIVEKEATKEAINAAMKAAAEGPMKGILEYNVDPIVSCDIVGNAHSCIFDSPLTMSSGNLIKVVGWYDNELGYAT
RVVDLLSIYSKFV

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=331, Percent_Identity=52.2658610271903, Blast_Score=338, Evalue=5e-93,
Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=50.4559270516717, Blast_Score=327, Evalue=1e-89,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=55.2870090634441, Blast_Score=364, Evalue=1e-102,
Organism=Escherichia coli, GI1789295, Length=326, Percent_Identity=43.2515337423313, Blast_Score=284, Evalue=7e-78,
Organism=Caenorhabditis elegans, GI17534677, Length=336, Percent_Identity=52.9761904761905, Blast_Score=338, Evalue=3e-93,
Organism=Caenorhabditis elegans, GI17534679, Length=336, Percent_Identity=52.6785714285714, Blast_Score=337, Evalue=4e-93,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=52.8189910979229, Blast_Score=332, Evalue=1e-91,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=52.8189910979229, Blast_Score=332, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6321631, Length=332, Percent_Identity=52.4096385542169, Blast_Score=342, Evalue=7e-95,
Organism=Saccharomyces cerevisiae, GI6322409, Length=332, Percent_Identity=51.2048192771084, Blast_Score=340, Evalue=1e-94,
Organism=Saccharomyces cerevisiae, GI6322468, Length=332, Percent_Identity=51.5060240963855, Blast_Score=335, Evalue=7e-93,
Organism=Drosophila melanogaster, GI85725000, Length=326, Percent_Identity=51.840490797546, Blast_Score=330, Evalue=1e-90,
Organism=Drosophila melanogaster, GI22023983, Length=326, Percent_Identity=51.840490797546, Blast_Score=330, Evalue=1e-90,
Organism=Drosophila melanogaster, GI17933600, Length=326, Percent_Identity=51.840490797546, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI18110149, Length=326, Percent_Identity=51.840490797546, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI19922412, Length=332, Percent_Identity=48.7951807228916, Blast_Score=307, Evalue=7e-84,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35631; Mature: 35500

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVKVGINGFGRIGRLVFRQAVDNPDVEIVGINDLTDVNTLAHLLKYDSTHKKFNGEVK
CCEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHCCCEEE
VEGDNLVVNGKTIAICAQRDPAELPWKSLGAELVVESTGIFTKREAAAKHIAAGAKKVII
EECCEEEECCCEEEEEECCCCCCCCHHHCCCEEEEECCCCEEHHHHHHHHHHCCCCEEEE
SAPAKDKVDATIVMGVNDDCITGNEEIVSNASCTTNCLAPMVKVLHENFGIVKGFMTTVH
ECCCCCCCCEEEEEECCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
AYTNDQNILDLPHKDLRRARSAANSIIPTSTGAAKAIGEVLPELAGKLDGFAMRVPVPDG
EECCCCCEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCC
SVTDLSVIVEKEATKEAINAAMKAAAEGPMKGILEYNVDPIVSCDIVGNAHSCIFDSPLT
CCCEEEEEEECHHHHHHHHHHHHHHHCCCHHHHEEECCCCEEEEEEECCCCCEEECCCCE
MSSGNLIKVVGWYDNELGYATRVVDLLSIYSKFV
ECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKVKVGINGFGRIGRLVFRQAVDNPDVEIVGINDLTDVNTLAHLLKYDSTHKKFNGEVK
CEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHCCCEEE
VEGDNLVVNGKTIAICAQRDPAELPWKSLGAELVVESTGIFTKREAAAKHIAAGAKKVII
EECCEEEECCCEEEEEECCCCCCCCHHHCCCEEEEECCCCEEHHHHHHHHHHCCCCEEEE
SAPAKDKVDATIVMGVNDDCITGNEEIVSNASCTTNCLAPMVKVLHENFGIVKGFMTTVH
ECCCCCCCCEEEEEECCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
AYTNDQNILDLPHKDLRRARSAANSIIPTSTGAAKAIGEVLPELAGKLDGFAMRVPVPDG
EECCCCCEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCC
SVTDLSVIVEKEATKEAINAAMKAAAEGPMKGILEYNVDPIVSCDIVGNAHSCIFDSPLT
CCCEEEEEEECHHHHHHHHHHHHHHHCCCHHHHEEECCCCEEEEEEECCCCCEEECCCCE
MSSGNLIKVVGWYDNELGYATRVVDLLSIYSKFV
ECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2684782; 2227448; 2656407; 7408868; 193030; 3586018; 9175858 [H]