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The map label for this gene is atpB1

Identifier: 193212723

GI number: 193212723

Start: 1176106

End: 1176786

Strand: Direct

Name: atpB1

Synonym: Cpar_1068

Alternate gene names: 193212723

Gene position: 1176106-1176786 (Clockwise)

Preceding gene: 193212722

Following gene: 193212724

Centisome position: 51.38

GC content: 60.79

Gene sequence:

>681_bases
ATGCATCTGAGCAGCGACGAGGTCGTCCTCTGGCAGTCGGGTTTTCTGAAGCTCAACCTGACCATCGTCACCACCTGGGC
GGTGATGCTGCTGCTCGCGGGCGGTTCGTGGCTCATCACGCGGCGGCTCTCGACCGGCATCACGATTTCGCGCTGGCAGA
GCGTGCTGGAGATCATCGTTACGATGGCGCGTCGGCAGATCGGCGAGGTCGGCCTGCAAAAGCCTGAAAAGTACCTCCCC
TTCATCGCAACGCTCTTCCTCTTCATCGCCACGGCGAACCTCTGCACGGTCATTCCCGGCTACGAACCGCCGACCGGTTC
GCTCTCCACCACGGCGGCGCTCGCGCTCTCGGTCTTCATCGCGGTGCCGCTCTTCGGAATCGCGGAGAGCGGCCTCGTGG
GCTACCTGAAAACCTACGCCGAACCGACGCCCATCATGCTCCCCTTCAACATCGTCGGCGAGCTGACCCGCACGATGGCG
CTTGCCGTGCGTCTGTTCGGCAACATGATGAGTGGCGACATGATTCTCGTCATTCTGCTGACGATTTCACCGCTCGTCTT
TCCGGTGCTGATGAACATCCTCGGCCTCTTGACCGGCATGGTGCAGGCCTACATTTTCAGCATCCTGGCCACGGTCTATA
TCGCCGCCGCAACCAGAACGCGCGAAAAATCAACAAGTTAA

Upstream 100 bases:

>100_bases
TGCTGCTGGCTGTCGGCGGATTCGTGGCGGCAAAAGTGACGAGCATCGTCCTCGGACGCCGCGACGGCGCGTCGGAACAT
CGCGGCAAAAAGGAGACACC

Downstream 100 bases:

>100_bases
CCAAACGAGAAACCATCATGGATACGCTCACCATCATCGCGATTGTCTCCATCGCCACCGCGGGACTGTCGATCGGCATC
GGCGTCATTGGCCCGGCACT

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a 1; F-ATPase subunit 6 1

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MHLSSDEVVLWQSGFLKLNLTIVTTWAVMLLLAGGSWLITRRLSTGITISRWQSVLEIIVTMARRQIGEVGLQKPEKYLP
FIATLFLFIATANLCTVIPGYEPPTGSLSTTAALALSVFIAVPLFGIAESGLVGYLKTYAEPTPIMLPFNIVGELTRTMA
LAVRLFGNMMSGDMILVILLTISPLVFPVLMNILGLLTGMVQAYIFSILATVYIAAATRTREKSTS

Sequences:

>Translated_226_residues
MHLSSDEVVLWQSGFLKLNLTIVTTWAVMLLLAGGSWLITRRLSTGITISRWQSVLEIIVTMARRQIGEVGLQKPEKYLP
FIATLFLFIATANLCTVIPGYEPPTGSLSTTAALALSVFIAVPLFGIAESGLVGYLKTYAEPTPIMLPFNIVGELTRTMA
LAVRLFGNMMSGDMILVILLTISPLVFPVLMNILGLLTGMVQAYIFSILATVYIAAATRTREKSTS
>Mature_226_residues
MHLSSDEVVLWQSGFLKLNLTIVTTWAVMLLLAGGSWLITRRLSTGITISRWQSVLEIIVTMARRQIGEVGLQKPEKYLP
FIATLFLFIATANLCTVIPGYEPPTGSLSTTAALALSVFIAVPLFGIAESGLVGYLKTYAEPTPIMLPFNIVGELTRTMA
LAVRLFGNMMSGDMILVILLTISPLVFPVLMNILGLLTGMVQAYIFSILATVYIAAATRTREKSTS

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=210, Percent_Identity=22.8571428571429, Blast_Score=61, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6226527, Length=234, Percent_Identity=26.4957264957265, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP61_CHLP8 (B3QNH3)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001998676.1
- GeneID:   6419998
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_1068
- HOGENOM:   HBG734175
- OMA:   QAYIFGM
- ProtClustDB:   PRK05815
- HAMAP:   MF_01393
- InterPro:   IPR017692
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR03306
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 24588; Mature: 24588

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1c8d4284)-; HASH(0x1c0a0474)-; HASH(0x1ccdc960)-; HASH(0x1c706aac)-; HASH(0x1cc9c434)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLSSDEVVLWQSGFLKLNLTIVTTWAVMLLLAGGSWLITRRLSTGITISRWQSVLEIIV
CCCCCCCEEEEECCCEEEEHHHHHHHHHHHHHHCCCCEEEEHHHCCCCHHHHHHHHHHHH
TMARRQIGEVGLQKPEKYLPFIATLFLFIATANLCTVIPGYEPPTGSLSTTAALALSVFI
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHH
AVPLFGIAESGLVGYLKTYAEPTPIMLPFNIVGELTRTMALAVRLFGNMMSGDMILVILL
HHHHHHHHHCHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TISPLVFPVLMNILGLLTGMVQAYIFSILATVYIAAATRTREKSTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
>Mature Secondary Structure
MHLSSDEVVLWQSGFLKLNLTIVTTWAVMLLLAGGSWLITRRLSTGITISRWQSVLEIIV
CCCCCCCEEEEECCCEEEEHHHHHHHHHHHHHHCCCCEEEEHHHCCCCHHHHHHHHHHHH
TMARRQIGEVGLQKPEKYLPFIATLFLFIATANLCTVIPGYEPPTGSLSTTAALALSVFI
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHH
AVPLFGIAESGLVGYLKTYAEPTPIMLPFNIVGELTRTMALAVRLFGNMMSGDMILVILL
HHHHHHHHHCHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TISPLVFPVLMNILGLLTGMVQAYIFSILATVYIAAATRTREKSTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA