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The map label for this gene is purQ

Identifier: 193212481

GI number: 193212481

Start: 889004

End: 889762

Strand: Direct

Name: purQ

Synonym: Cpar_0818

Alternate gene names: 193212481

Gene position: 889004-889762 (Clockwise)

Preceding gene: 193212480

Following gene: 193212482

Centisome position: 38.83

GC content: 57.18

Gene sequence:

>759_bases
ATGGCTGATCTCAACGTTGGCGTCGTGGTGTTTCCCGGTTCGAACTGCGACCACGATACCGAATATGCCGTTGCCTCGTT
TTCCGGAGTCAAGCCGGTCATGCTCTGGCACAACGAGCACGACCTGAAAGGCTGCGACGCGATTATTCTCCCTGGTGGCT
TCTCCTACGGCGATTACCTCCGCTGTGGCTCCATCGCCCGCTTCTCGCCGATCATGCGTGAAGTGATCGACTTCGCAGGG
CAAGGCCGTCCGGTGCTCGGCATCTGCAACGGTTTTCAGGTGCTGGTCGAAAGCGGCCTGCTCGAAGGCGCGCTGATCCG
CAACGCTGGTCGGAAGTTTATCTGCCGTCAGTCAACCATCAGCGTGGTGAACAACTCGACCATCTTTACCGATCGTTACG
AAAAGGGCGAAGTGCTTCGCGTGCCGGTTGCGCATGGTGAGGGCAACTACTACGCCTCCGTTGAGACCATCGACAGCCTC
GAATCGAACGGCCAGGTGGTTTTCCGTTATACTGATGCGGAAGGCAATGCTACTGCCGAAGCTAATTTCAACGGATCGCT
GAACAACATCGCCGGTATTACCAACAAGCAGGGCAACGTGCTCGGCCTGATGCCGCATCCCGAGCGGGCCAGCGAAGAGC
TGCTCGGCTCTGGTGATGGCCGCAGAGTTTTCGAATCCCTGTTTGCTCATCTTGCCGGAACAAAAAGATCTTCTCGTGGC
TGCTGTTCGACTTCGCCAACACGTCGTTCAGCGTCATGA

Upstream 100 bases:

>100_bases
GAAGGTCGCGATCGAAATCTGTCAGAAACTCCTGTCGAATCCGGTGATGGAAGATTTCACTTTCGAACTGGAACCCGTCA
ACTAAATTTCGCTTTTTGCT

Downstream 100 bases:

>100_bases
TGGTCACTTTCGCCTTTCCCCTCTATTTTAAAAACGTCATCTGCCAGGGCGATCCCCAGGGCGACCAGCTCTGGGGCAAC
AGCGTCAGCATTTCGATGCT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MADLNVGVVVFPGSNCDHDTEYAVASFSGVKPVMLWHNEHDLKGCDAIILPGGFSYGDYLRCGSIARFSPIMREVIDFAG
QGRPVLGICNGFQVLVESGLLEGALIRNAGRKFICRQSTISVVNNSTIFTDRYEKGEVLRVPVAHGEGNYYASVETIDSL
ESNGQVVFRYTDAEGNATAEANFNGSLNNIAGITNKQGNVLGLMPHPERASEELLGSGDGRRVFESLFAHLAGTKRSSRG
CCSTSPTRRSAS

Sequences:

>Translated_252_residues
MADLNVGVVVFPGSNCDHDTEYAVASFSGVKPVMLWHNEHDLKGCDAIILPGGFSYGDYLRCGSIARFSPIMREVIDFAG
QGRPVLGICNGFQVLVESGLLEGALIRNAGRKFICRQSTISVVNNSTIFTDRYEKGEVLRVPVAHGEGNYYASVETIDSL
ESNGQVVFRYTDAEGNATAEANFNGSLNNIAGITNKQGNVLGLMPHPERASEELLGSGDGRRVFESLFAHLAGTKRSSRG
CCSTSPTRRSAS
>Mature_251_residues
ADLNVGVVVFPGSNCDHDTEYAVASFSGVKPVMLWHNEHDLKGCDAIILPGGFSYGDYLRCGSIARFSPIMREVIDFAGQ
GRPVLGICNGFQVLVESGLLEGALIRNAGRKFICRQSTISVVNNSTIFTDRYEKGEVLRVPVAHGEGNYYASVETIDSLE
SNGQVVFRYTDAEGNATAEANFNGSLNNIAGITNKQGNVLGLMPHPERASEELLGSGDGRRVFESLFAHLAGTKRSSRGC
CSTSPTRRSAS

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI48994899, Length=183, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17553022, Length=196, Percent_Identity=27.0408163265306, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6321498, Length=187, Percent_Identity=33.1550802139037, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24582111, Length=190, Percent_Identity=33.1578947368421, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24582109, Length=190, Percent_Identity=33.1578947368421, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI17137292, Length=190, Percent_Identity=33.1578947368421, Blast_Score=84, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURQ_CHLP8 (B3QMT1)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001998434.1
- ProteinModelPortal:   B3QMT1
- GeneID:   6419747
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_0818
- HOGENOM:   HBG302712
- OMA:   FPGTNCD
- ProtClustDB:   PRK03619
- GO:   GO:0005737
- HAMAP:   MF_00421
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075
- PIRSF:   PIRSF001586
- TIGRFAMs:   TIGR01737

Pfam domain/function: PF00117 GATase

EC number: =6.3.5.3

Molecular weight: Translated: 27102; Mature: 26971

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS51273 GATASE_TYPE_1; PS00442 GATASE_TYPE_I

Important sites: ACT_SITE 89-89 ACT_SITE 206-206 ACT_SITE 208-208

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLNVGVVVFPGSNCDHDTEYAVASFSGVKPVMLWHNEHDLKGCDAIILPGGFSYGDYL
CCCCCEEEEEECCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCEEEECCCCCCCCHH
RCGSIARFSPIMREVIDFAGQGRPVLGICNGFQVLVESGLLEGALIRNAGRKFICRQSTI
CCCCCHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHCCCHHHHHHHHCCCEEEEECCEE
SVVNNSTIFTDRYEKGEVLRVPVAHGEGNYYASVETIDSLESNGQVVFRYTDAEGNATAE
EEECCCEEEEECCCCCCEEEEEEEECCCCEEEEEEEHHHHCCCCEEEEEEECCCCCEEEE
ANFNGSLNNIAGITNKQGNVLGLMPHPERASEELLGSGDGRRVFESLFAHLAGTKRSSRG
ECCCCCCHHCCCCCCCCCCEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
CCSTSPTRRSAS
CCCCCCCCCCCC
>Mature Secondary Structure 
ADLNVGVVVFPGSNCDHDTEYAVASFSGVKPVMLWHNEHDLKGCDAIILPGGFSYGDYL
CCCCEEEEEECCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCEEEECCCCCCCCHH
RCGSIARFSPIMREVIDFAGQGRPVLGICNGFQVLVESGLLEGALIRNAGRKFICRQSTI
CCCCCHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHCCCHHHHHHHHCCCEEEEECCEE
SVVNNSTIFTDRYEKGEVLRVPVAHGEGNYYASVETIDSLESNGQVVFRYTDAEGNATAE
EEECCCEEEEECCCCCCEEEEEEEECCCCEEEEEEEHHHHCCCCEEEEEEECCCCCEEEE
ANFNGSLNNIAGITNKQGNVLGLMPHPERASEELLGSGDGRRVFESLFAHLAGTKRSSRG
ECCCCCCHHCCCCCCCCCCEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
CCSTSPTRRSAS
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA