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The map label for this gene is aspC [H]

Identifier: 193212445

GI number: 193212445

Start: 844547

End: 845710

Strand: Direct

Name: aspC [H]

Synonym: Cpar_0782

Alternate gene names: 193212445

Gene position: 844547-845710 (Clockwise)

Preceding gene: 193212444

Following gene: 193212446

Centisome position: 36.89

GC content: 60.22

Gene sequence:

>1164_bases
ATGAGCCTGAACCTTGCCGATCGCTGCGATCTGGTGATGCAGTCCGATATCCGTACCATGTCGCTCGAGTGCGCCCGGAT
CGGGGGCATCAACCTTTCGCAGGGAATCTGCGATACGCCGGTGCCGCCGGAAGTGCTGCGTGGAGCGGCCGATGCCGTCA
TGCAGGGGCCCAACATCTACACCCATTACGCTGGTTTGCACGAGCTTCGCCAGGCAATCGCTGATAAGCAACGGCGATTC
AGCGGCATGGAACTCGACCCTGAGCGCGAAGTCGTGATTTCGGCTGGCGCGACCGGTGCGATGTACTGCGCGTTTCAGAC
CCTGCTCAATCGCGGTGACGAGGTGCTGGTGTTCGAGCCGTTTTATGGGTACCACGTTTCGACGCTTCGAGCGGTCGAGG
CCGTGCCGGTGTTCGTGCCGCTCGATCCGCCTCACTGGTCGTTTGCGCTCGAAGCGCTCGAAGCAGCGGTGACACCGAAC
ACCAAAGCTATTCTGATCAACACCCCCGCCAACCCCTCCGGCAAGGTCTTCTCGCGCGAGGAGCTTTCGCTTCTGGCGGA
GTTTGCCATTCGTCACGATCTGTTTGTGCTGACCGACGAGATGTACGAACATTTCGTCTTTGACGGACGTGCGCATGTCT
CGATGGCCACCTTGCCCGGCATGAGAGAACGGACGATTACCGTGTCAGGCCTCTCCAAAACCTTCAGCATCACGGGCTGG
CGCATCGGCTACGCCATGTGCGATGCGCGCTGGGCCGGCGCGATTGGCTACTTCAACGATCTTTGCTACGTCTGCGCGCC
GTCGCCGCTTCAGGCTGGCGTCACCCTCGGGCTTCGCAGCCTCGACGATAGCTATTACCACGGGCTTTCAGCCGAGTATG
AAGCCAAGCGCAACCGCTTCTGCGCGGCGCTTTCCGAGGCCGGTCTCGATCCGTTCATCCCCGAAGGAGCTTACTACGTG
CTTGCAAACACGGACGGCTTGCCGGGCGAAACGGCCCGGGAGCGGGCGATGCATATTCTCCATCATACCGGTGTCGCATC
GGTACCCGGTTCGGCGTTTTTTCACGGCACAGGTGGTGAGAATCTTGTCCGCTTCTGCTTCGCCAAAGAGCAGTCGGTGC
TGGACGAGGCTTGTGAAAAACTGCAAAAACTTCGAACGCTCTGA

Upstream 100 bases:

>100_bases
TGGCGGCATGGAGATATTTTCCGACCTGTTCCGGCAGTTTTCCAGTTATTGATGTGCGGGTCGGCCAGCTTGTTTTTTCA
CCCTTGAACGTATCCATCTC

Downstream 100 bases:

>100_bases
ACCATTTTTCAAGCGGTTGCGAAACCTCTCCGAGGCAGCGGTTGTTTTACACAAAGAAGCAGGGCCGTGGCCTCTGGTAG
AGCACGCAGCCCTGCCGATT

Product: class I and II aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSLNLADRCDLVMQSDIRTMSLECARIGGINLSQGICDTPVPPEVLRGAADAVMQGPNIYTHYAGLHELRQAIADKQRRF
SGMELDPEREVVISAGATGAMYCAFQTLLNRGDEVLVFEPFYGYHVSTLRAVEAVPVFVPLDPPHWSFALEALEAAVTPN
TKAILINTPANPSGKVFSREELSLLAEFAIRHDLFVLTDEMYEHFVFDGRAHVSMATLPGMRERTITVSGLSKTFSITGW
RIGYAMCDARWAGAIGYFNDLCYVCAPSPLQAGVTLGLRSLDDSYYHGLSAEYEAKRNRFCAALSEAGLDPFIPEGAYYV
LANTDGLPGETARERAMHILHHTGVASVPGSAFFHGTGGENLVRFCFAKEQSVLDEACEKLQKLRTL

Sequences:

>Translated_387_residues
MSLNLADRCDLVMQSDIRTMSLECARIGGINLSQGICDTPVPPEVLRGAADAVMQGPNIYTHYAGLHELRQAIADKQRRF
SGMELDPEREVVISAGATGAMYCAFQTLLNRGDEVLVFEPFYGYHVSTLRAVEAVPVFVPLDPPHWSFALEALEAAVTPN
TKAILINTPANPSGKVFSREELSLLAEFAIRHDLFVLTDEMYEHFVFDGRAHVSMATLPGMRERTITVSGLSKTFSITGW
RIGYAMCDARWAGAIGYFNDLCYVCAPSPLQAGVTLGLRSLDDSYYHGLSAEYEAKRNRFCAALSEAGLDPFIPEGAYYV
LANTDGLPGETARERAMHILHHTGVASVPGSAFFHGTGGENLVRFCFAKEQSVLDEACEKLQKLRTL
>Mature_386_residues
SLNLADRCDLVMQSDIRTMSLECARIGGINLSQGICDTPVPPEVLRGAADAVMQGPNIYTHYAGLHELRQAIADKQRRFS
GMELDPEREVVISAGATGAMYCAFQTLLNRGDEVLVFEPFYGYHVSTLRAVEAVPVFVPLDPPHWSFALEALEAAVTPNT
KAILINTPANPSGKVFSREELSLLAEFAIRHDLFVLTDEMYEHFVFDGRAHVSMATLPGMRERTITVSGLSKTFSITGWR
IGYAMCDARWAGAIGYFNDLCYVCAPSPLQAGVTLGLRSLDDSYYHGLSAEYEAKRNRFCAALSEAGLDPFIPEGAYYVL
ANTDGLPGETARERAMHILHHTGVASVPGSAFFHGTGGENLVRFCFAKEQSVLDEACEKLQKLRTL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=383, Percent_Identity=32.1148825065274, Blast_Score=222, Evalue=6e-58,
Organism=Homo sapiens, GI56713256, Length=383, Percent_Identity=32.1148825065274, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI95147551, Length=391, Percent_Identity=32.4808184143223, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI169881279, Length=391, Percent_Identity=32.4808184143223, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI169881281, Length=303, Percent_Identity=31.3531353135314, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI4507369, Length=360, Percent_Identity=24.1666666666667, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI149944424, Length=218, Percent_Identity=30.7339449541284, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI187936925, Length=205, Percent_Identity=30.7317073170732, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI14211921, Length=205, Percent_Identity=30.7317073170732, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1786816, Length=365, Percent_Identity=32.0547945205479, Blast_Score=205, Evalue=4e-54,
Organism=Escherichia coli, GI1788722, Length=365, Percent_Identity=25.7534246575342, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788627, Length=307, Percent_Identity=30.2931596091205, Blast_Score=111, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71994472, Length=395, Percent_Identity=31.6455696202532, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI71994476, Length=395, Percent_Identity=31.6455696202532, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17567369, Length=391, Percent_Identity=28.1329923273657, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17567663, Length=294, Percent_Identity=24.4897959183673, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=31.8766066838046, Blast_Score=184, Evalue=2e-47,
Organism=Drosophila melanogaster, GI28573069, Length=387, Percent_Identity=34.3669250645995, Blast_Score=217, Evalue=9e-57,
Organism=Drosophila melanogaster, GI24646114, Length=387, Percent_Identity=34.3669250645995, Blast_Score=217, Evalue=9e-57,
Organism=Drosophila melanogaster, GI28573067, Length=387, Percent_Identity=34.3669250645995, Blast_Score=217, Evalue=9e-57,
Organism=Drosophila melanogaster, GI28573065, Length=387, Percent_Identity=34.3669250645995, Blast_Score=217, Evalue=9e-57,
Organism=Drosophila melanogaster, GI18859735, Length=337, Percent_Identity=28.1899109792285, Blast_Score=116, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42441; Mature: 42310

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNLADRCDLVMQSDIRTMSLECARIGGINLSQGICDTPVPPEVLRGAADAVMQGPNIY
CCCCCCHHHHHHHHCCCHHEEEEHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEE
THYAGLHELRQAIADKQRRFSGMELDPEREVVISAGATGAMYCAFQTLLNRGDEVLVFEP
EHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEECC
FYGYHVSTLRAVEAVPVFVPLDPPHWSFALEALEAAVTPNTKAILINTPANPSGKVFSRE
CCCCHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEECHH
ELSLLAEFAIRHDLFVLTDEMYEHFVFDGRAHVSMATLPGMRERTITVSGLSKTFSITGW
HHHHHHHHHHHHHHEEEEHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCEEEECCE
RIGYAMCDARWAGAIGYFNDLCYVCAPSPLQAGVTLGLRSLDDSYYHGLSAEYEAKRNRF
EEHHHHHCCHHHCHHHHHHCEEEEECCCCHHCCHHHHHHHCCHHHHCCCCCHHHHHHHHH
CAALSEAGLDPFIPEGAYYVLANTDGLPGETARERAMHILHHTGVASVPGSAFFHGTGGE
HHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCH
NLVRFCFAKEQSVLDEACEKLQKLRTL
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLNLADRCDLVMQSDIRTMSLECARIGGINLSQGICDTPVPPEVLRGAADAVMQGPNIY
CCCCCHHHHHHHHCCCHHEEEEHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEE
THYAGLHELRQAIADKQRRFSGMELDPEREVVISAGATGAMYCAFQTLLNRGDEVLVFEP
EHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEECC
FYGYHVSTLRAVEAVPVFVPLDPPHWSFALEALEAAVTPNTKAILINTPANPSGKVFSRE
CCCCHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEECHH
ELSLLAEFAIRHDLFVLTDEMYEHFVFDGRAHVSMATLPGMRERTITVSGLSKTFSITGW
HHHHHHHHHHHHHHEEEEHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCEEEECCE
RIGYAMCDARWAGAIGYFNDLCYVCAPSPLQAGVTLGLRSLDDSYYHGLSAEYEAKRNRF
EEHHHHHCCHHHCHHHHHHCEEEEECCCCHHCCHHHHHHHCCHHHHCCCCCHHHHHHHHH
CAALSEAGLDPFIPEGAYYVLANTDGLPGETARERAMHILHHTGVASVPGSAFFHGTGGE
HHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCH
NLVRFCFAKEQSVLDEACEKLQKLRTL
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]