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The map label for this gene is typA [H]

Identifier: 193212404

GI number: 193212404

Start: 796728

End: 798572

Strand: Direct

Name: typA [H]

Synonym: Cpar_0740

Alternate gene names: 193212404

Gene position: 796728-798572 (Clockwise)

Preceding gene: 193212399

Following gene: 193212408

Centisome position: 34.8

GC content: 59.13

Gene sequence:

>1845_bases
ATGAGCAGGAAACAGAATATTCGCAATATCGCCATTATCGCGCACGTTGACCACGGAAAGACGACCCTTGTCGATTCGAT
TTTTCAGCAGACAGGTGCTTTCAGGGAAAACCAGCAGGTGGATGTCAGGGTGATGGACTCCAATCCCCAGGAGCGGGAGC
GGGGCATTACCATCTTCTCCAAAAACGCCGCCGCACAGCACAAGGGCTGCAAGATCAACATCGTCGACACTCCTGGTCAC
GCCGATTTCGGCGGCGAGGTCGAGCGCATCCTGAAGATGGTGGATGGCGTGCTCCTGCTTGTCGATGCCTTCGAAGGCCC
GATGCCGCAGACCAAGTTTGTGCTTCGCAAGGCGCTCGAACTGCACCTGAAGCCGATCGTGGTTATCAACAAGATCGACC
GCCCGCAGGCCGATCCGGAGAAGGTGCACGATCAGGTGCTCGACCTGTTCATCGCGCTTGGCGCCGACGAGGACCAGCTC
GATTTCCCCTACATCTTCGCTTCGGCCAAGAACGGCATTGCCAAATATGATATGGCGGATCCGGACGGCGACATGAGCCT
TCTGCTCGACATGATCGTCAAGGAGATTCCCGCCCCTGAAGCGGATGACGACGCCGGATTCCAGATGCTCGTCACCAGCC
TCGACTACAATGACTATATCGGCAAGATCGCCATCGGCCGCATCCAGCGCGGCAAGGTCGCGCCCGGCAACCAGCTCACG
CTGGTGACGCAGGATGGTGTTGTCGGCAAGGGTACGGTCACCAAGCTCTTCCTCTTCGACCGCACGCAGCGCGTCGAGGC
GACCGAAGCGACGGCGGGCGACATCGTCGCACTTGCCGGTATCGCGGCGGCCAACGTCGGCGAAACCCTCACCACCCCCG
ACCAGCCCGAACCGCTCGAATCGTTCGAGATCAGCAAGCCGACCCTTTCGATGCTCTTTTCGGTGAACGATTCGCCGTTC
GCCGGTCAGGAGGGCAAGGAGGTGACCAGCCGCAAGATTCGCGAGCGCCTGATGAAGGAGATCATGACCAACGTCGCGCT
GAACGTTGAGGAGACCGACAGCGCCGACACCTTCCGGGTTTCGGGCCGCGGCGAGCTTCACCTCTCCGTGCTCATCGAGA
CGATGCGCCGCGAGGGCTACGAGCTCGCGATCTCCCGTCCTGAGGTGATTCTCCGCGAGGAGAACGGCGTGAAGATGGAG
CCGGTCGAGCATGTTACCATCGACGTTCCGGAAGAGTACACCGGCGTGGTCATCGAGAAGATGGGGCGCAGGAAGGCTGA
GATGACCCACATGGGAACCCTTCGCGGCGGCATGAACCGACTTGAGTTCGAAATTCCGACCCGAGGCCTGATCGGTTACA
ACCTTGAGTTCACCACCGATACCAAAGGCGAGGGTATCATGTCGCACGTTTTCCACAACTACCAGCCTTTCAAGGGCAAG
CTGCCGTCACGCGAAACCGGCGCGCTTGTCTCTGCCGAAACCGGCGTGGCCGTGGCCTATGCTCTTTCGAGCCTCGAAGA
TCGCGGCACTTTCTTCATCGGGCCGAACACGAAGGTCTACGAAGGTATGGTGGTTGGCGAGTCGACGCGTGACCTCGACA
TTACGATGAACATCTGCAAAACCAAGAAGCTCACCAACATGCGCGCTTCCGGTTCGGATGAGTCGATGAGGCTTACGCCG
CCGCGCAAGTTGTCGCTCGAACAGGCACTCGAGTTCATCAACGACGACGAGCTGCTCGAAGTGACGCCGGAGAACATCCG
CATTCGCAAGAAGATTCTCAACGCCGACCAGCGCCAGAAGGCTGCCAAAAAAAGCCAAAGCAATGGTGTGAGGGGAGAAT
TTTGA

Upstream 100 bases:

>100_bases
CAAGGCTTTTCATTCCCGCCCTGCAATATAATCAAAGGAAAAAGTGTATATTCGCCACGAGTGAACTCAAGTCTACAAAT
ATACTTATTTATCGCCAAAG

Downstream 100 bases:

>100_bases
TACTTGATAATGAAAAAGGCTGCTCCGAGTGGGCAGCCTTTTTTGTTGGGTGAGCAAAAAAAAAGATCAGTCGGATCAGT
CGGATCAGTCAGATCGGACT

Product: GTP-binding protein TypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 614; Mature: 613

Protein sequence:

>614_residues
MSRKQNIRNIAIIAHVDHGKTTLVDSIFQQTGAFRENQQVDVRVMDSNPQERERGITIFSKNAAAQHKGCKINIVDTPGH
ADFGGEVERILKMVDGVLLLVDAFEGPMPQTKFVLRKALELHLKPIVVINKIDRPQADPEKVHDQVLDLFIALGADEDQL
DFPYIFASAKNGIAKYDMADPDGDMSLLLDMIVKEIPAPEADDDAGFQMLVTSLDYNDYIGKIAIGRIQRGKVAPGNQLT
LVTQDGVVGKGTVTKLFLFDRTQRVEATEATAGDIVALAGIAAANVGETLTTPDQPEPLESFEISKPTLSMLFSVNDSPF
AGQEGKEVTSRKIRERLMKEIMTNVALNVEETDSADTFRVSGRGELHLSVLIETMRREGYELAISRPEVILREENGVKME
PVEHVTIDVPEEYTGVVIEKMGRRKAEMTHMGTLRGGMNRLEFEIPTRGLIGYNLEFTTDTKGEGIMSHVFHNYQPFKGK
LPSRETGALVSAETGVAVAYALSSLEDRGTFFIGPNTKVYEGMVVGESTRDLDITMNICKTKKLTNMRASGSDESMRLTP
PRKLSLEQALEFINDDELLEVTPENIRIRKKILNADQRQKAAKKSQSNGVRGEF

Sequences:

>Translated_614_residues
MSRKQNIRNIAIIAHVDHGKTTLVDSIFQQTGAFRENQQVDVRVMDSNPQERERGITIFSKNAAAQHKGCKINIVDTPGH
ADFGGEVERILKMVDGVLLLVDAFEGPMPQTKFVLRKALELHLKPIVVINKIDRPQADPEKVHDQVLDLFIALGADEDQL
DFPYIFASAKNGIAKYDMADPDGDMSLLLDMIVKEIPAPEADDDAGFQMLVTSLDYNDYIGKIAIGRIQRGKVAPGNQLT
LVTQDGVVGKGTVTKLFLFDRTQRVEATEATAGDIVALAGIAAANVGETLTTPDQPEPLESFEISKPTLSMLFSVNDSPF
AGQEGKEVTSRKIRERLMKEIMTNVALNVEETDSADTFRVSGRGELHLSVLIETMRREGYELAISRPEVILREENGVKME
PVEHVTIDVPEEYTGVVIEKMGRRKAEMTHMGTLRGGMNRLEFEIPTRGLIGYNLEFTTDTKGEGIMSHVFHNYQPFKGK
LPSRETGALVSAETGVAVAYALSSLEDRGTFFIGPNTKVYEGMVVGESTRDLDITMNICKTKKLTNMRASGSDESMRLTP
PRKLSLEQALEFINDDELLEVTPENIRIRKKILNADQRQKAAKKSQSNGVRGEF
>Mature_613_residues
SRKQNIRNIAIIAHVDHGKTTLVDSIFQQTGAFRENQQVDVRVMDSNPQERERGITIFSKNAAAQHKGCKINIVDTPGHA
DFGGEVERILKMVDGVLLLVDAFEGPMPQTKFVLRKALELHLKPIVVINKIDRPQADPEKVHDQVLDLFIALGADEDQLD
FPYIFASAKNGIAKYDMADPDGDMSLLLDMIVKEIPAPEADDDAGFQMLVTSLDYNDYIGKIAIGRIQRGKVAPGNQLTL
VTQDGVVGKGTVTKLFLFDRTQRVEATEATAGDIVALAGIAAANVGETLTTPDQPEPLESFEISKPTLSMLFSVNDSPFA
GQEGKEVTSRKIRERLMKEIMTNVALNVEETDSADTFRVSGRGELHLSVLIETMRREGYELAISRPEVILREENGVKMEP
VEHVTIDVPEEYTGVVIEKMGRRKAEMTHMGTLRGGMNRLEFEIPTRGLIGYNLEFTTDTKGEGIMSHVFHNYQPFKGKL
PSRETGALVSAETGVAVAYALSSLEDRGTFFIGPNTKVYEGMVVGESTRDLDITMNICKTKKLTNMRASGSDESMRLTPP
RKLSLEQALEFINDDELLEVTPENIRIRKKILNADQRQKAAKKSQSNGVRGEF

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=473, Percent_Identity=28.9640591966173, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI94966754, Length=133, Percent_Identity=45.1127819548872, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI4503483, Length=150, Percent_Identity=40.6666666666667, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI18390331, Length=147, Percent_Identity=40.8163265306122, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI25306287, Length=133, Percent_Identity=42.8571428571429, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI19923640, Length=133, Percent_Identity=42.8571428571429, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI25306283, Length=133, Percent_Identity=42.8571428571429, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI34147630, Length=268, Percent_Identity=29.1044776119403, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI310132016, Length=111, Percent_Identity=40.5405405405405, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI310110807, Length=111, Percent_Identity=40.5405405405405, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI310123363, Length=111, Percent_Identity=40.5405405405405, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI217272892, Length=140, Percent_Identity=37.8571428571429, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI217272894, Length=140, Percent_Identity=37.8571428571429, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI94966752, Length=129, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI53729339, Length=138, Percent_Identity=35.5072463768116, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI53729337, Length=138, Percent_Identity=35.5072463768116, Blast_Score=73, Evalue=9e-13,
Organism=Escherichia coli, GI48994988, Length=605, Percent_Identity=53.5537190082645, Blast_Score=648, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=511, Percent_Identity=29.5499021526419, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1789738, Length=167, Percent_Identity=38.9221556886228, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1790412, Length=326, Percent_Identity=27.9141104294479, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789737, Length=326, Percent_Identity=27.9141104294479, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790835, Length=149, Percent_Identity=33.5570469798658, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789559, Length=164, Percent_Identity=31.7073170731707, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17557151, Length=323, Percent_Identity=34.3653250773994, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17506493, Length=217, Percent_Identity=33.6405529953917, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI71988819, Length=130, Percent_Identity=40.7692307692308, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71988811, Length=130, Percent_Identity=40.7692307692308, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17556745, Length=142, Percent_Identity=41.5492957746479, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17533571, Length=145, Percent_Identity=41.3793103448276, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17552882, Length=134, Percent_Identity=37.3134328358209, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17556456, Length=261, Percent_Identity=27.5862068965517, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI25141371, Length=270, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994658, Length=153, Percent_Identity=33.9869281045752, Blast_Score=69, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6323320, Length=488, Percent_Identity=29.3032786885246, Blast_Score=138, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6324707, Length=150, Percent_Identity=42.6666666666667, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6320593, Length=150, Percent_Identity=42.6666666666667, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324761, Length=273, Percent_Identity=33.6996336996337, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324166, Length=180, Percent_Identity=37.7777777777778, Blast_Score=100, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6323098, Length=155, Percent_Identity=37.4193548387097, Blast_Score=95, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6322359, Length=149, Percent_Identity=37.5838926174497, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI78706572, Length=549, Percent_Identity=26.9581056466302, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28574573, Length=193, Percent_Identity=38.3419689119171, Blast_Score=116, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24585709, Length=167, Percent_Identity=38.3233532934132, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24585711, Length=167, Percent_Identity=38.3233532934132, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24585713, Length=167, Percent_Identity=38.3233532934132, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24582462, Length=147, Percent_Identity=42.1768707482993, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21357743, Length=134, Percent_Identity=38.8059701492537, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281363316, Length=272, Percent_Identity=31.9852941176471, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17864358, Length=272, Percent_Identity=31.9852941176471, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI221458488, Length=164, Percent_Identity=40.8536585365854, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19921738, Length=231, Percent_Identity=30.3030303030303, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28572034, Length=231, Percent_Identity=28.1385281385281, Blast_Score=73, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 68008; Mature: 67876

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00216 SUGAR_TRANSPORT_1 ; PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKQNIRNIAIIAHVDHGKTTLVDSIFQQTGAFRENQQVDVRVMDSNPQERERGITIFS
CCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHCCCEEEE
KNAAAQHKGCKINIVDTPGHADFGGEVERILKMVDGVLLLVDAFEGPMPQTKFVLRKALE
CCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHH
LHLKPIVVINKIDRPQADPEKVHDQVLDLFIALGADEDQLDFPYIFASAKNGIAKYDMAD
HHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEECCCCC
PDGDMSLLLDMIVKEIPAPEADDDAGFQMLVTSLDYNDYIGKIAIGRIQRGKVAPGNQLT
CCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHCCEEECEEECCCCCCCCEEE
LVTQDGVVGKGTVTKLFLFDRTQRVEATEATAGDIVALAGIAAANVGETLTTPDQPEPLE
EEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
SFEISKPTLSMLFSVNDSPFAGQEGKEVTSRKIRERLMKEIMTNVALNVEETDSADTFRV
CCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECEECCCCCCEEEE
SGRGELHLSVLIETMRREGYELAISRPEVILREENGVKMEPVEHVTIDVPEEYTGVVIEK
CCCCCEEHHHHHHHHHCCCCEEEECCCEEEEECCCCCEECCCCEEEEECCCHHHHHHHHH
MGRRKAEMTHMGTLRGGMNRLEFEIPTRGLIGYNLEFTTDTKGEGIMSHVFHNYQPFKGK
HCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEEECCCCCCHHHHHHHHCCCCCCCC
LPSRETGALVSAETGVAVAYALSSLEDRGTFFIGPNTKVYEGMVVGESTRDLDITMNICK
CCCCCCCCEEECCCCHHHHHHHHHHCCCCCEEECCCCEEEEEEEECCCCCCEEEEEEEHH
TKKLTNMRASGSDESMRLTPPRKLSLEQALEFINDDELLEVTPENIRIRKKILNADQRQK
CHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHCCCCCEEEECCCHHHHHHHHHCCHHHHH
AAKKSQSNGVRGEF
HHHHHHCCCCCCCC
>Mature Secondary Structure 
SRKQNIRNIAIIAHVDHGKTTLVDSIFQQTGAFRENQQVDVRVMDSNPQERERGITIFS
CCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHCCCEEEE
KNAAAQHKGCKINIVDTPGHADFGGEVERILKMVDGVLLLVDAFEGPMPQTKFVLRKALE
CCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHH
LHLKPIVVINKIDRPQADPEKVHDQVLDLFIALGADEDQLDFPYIFASAKNGIAKYDMAD
HHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEECCCCC
PDGDMSLLLDMIVKEIPAPEADDDAGFQMLVTSLDYNDYIGKIAIGRIQRGKVAPGNQLT
CCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHCCEEECEEECCCCCCCCEEE
LVTQDGVVGKGTVTKLFLFDRTQRVEATEATAGDIVALAGIAAANVGETLTTPDQPEPLE
EEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
SFEISKPTLSMLFSVNDSPFAGQEGKEVTSRKIRERLMKEIMTNVALNVEETDSADTFRV
CCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECEECCCCCCEEEE
SGRGELHLSVLIETMRREGYELAISRPEVILREENGVKMEPVEHVTIDVPEEYTGVVIEK
CCCCCEEHHHHHHHHHCCCCEEEECCCEEEEECCCCCEECCCCEEEEECCCHHHHHHHHH
MGRRKAEMTHMGTLRGGMNRLEFEIPTRGLIGYNLEFTTDTKGEGIMSHVFHNYQPFKGK
HCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEEECCCCCCHHHHHHHHCCCCCCCC
LPSRETGALVSAETGVAVAYALSSLEDRGTFFIGPNTKVYEGMVVGESTRDLDITMNICK
CCCCCCCCEEECCCCHHHHHHHHHHCCCCCEEECCCCEEEEEEEECCCCCCEEEEEEEHH
TKKLTNMRASGSDESMRLTPPRKLSLEQALEFINDDELLEVTPENIRIRKKILNADQRQK
CHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHCCCCCEEEECCCHHHHHHHHHCCHHHHH
AAKKSQSNGVRGEF
HHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]