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The map label for this gene is nudG [H]

Identifier: 193212331

GI number: 193212331

Start: 711546

End: 711947

Strand: Direct

Name: nudG [H]

Synonym: Cpar_0664

Alternate gene names: 193212331

Gene position: 711546-711947 (Clockwise)

Preceding gene: 193212330

Following gene: 193212332

Centisome position: 31.08

GC content: 57.71

Gene sequence:

>402_bases
ATGCACATAGGTGATGTGGTTTGCGCCATCATTGAGCGCGATGGAAAGTTTCTCATAGCTCGGCGGCCGGACGACGGAAG
GCATCTGGCGCGGAAGTGGGAGTTTCCGGGCGGGAAAGTTGAGCCGGGGGAGTCGGCGACTGCCGCCTTGGCGCGGGAGC
TTCGAGAGGAGCTCGACGTGTCGGTAACGATTATCGAGCAACTGACCCCTGTGGAGCATCGCTATCCGGAGCTTTCGCTG
CGGTTGATCGCTTTCCGTTGTCGCTTGACGAGTGGCACGCCGCAGGCTGGGGCTCATGAGGAGTTGCGCTGGATTGGTAT
CGAGGAGGTCGCGGATTACGATTTTCCTGAAGCCGATCTTCCCATTCTTGCCGAGTATCGCATCAAAAACTCTTTTCAGT
AA

Upstream 100 bases:

>100_bases
AACAATGTGATCGCCAAAACGGTCAACTACCGGGCTGTGAAGCAGTGATGGGTTTGGTTTATGTCGTGGTTTTTAAGTTT
ATCGTTGTTGCCTGATTTTT

Downstream 100 bases:

>100_bases
ACGAAGTCAGCCGATTCTGATTCTCCTGATTGAGCAATTTTGCTTTTTGTATTCCGTTTGCGCTTGCGATTTACCGCTTA
TGTTTTTCAGCTCACAATTT

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MHIGDVVCAIIERDGKFLIARRPDDGRHLARKWEFPGGKVEPGESATAALARELREELDVSVTIIEQLTPVEHRYPELSL
RLIAFRCRLTSGTPQAGAHEELRWIGIEEVADYDFPEADLPILAEYRIKNSFQ

Sequences:

>Translated_133_residues
MHIGDVVCAIIERDGKFLIARRPDDGRHLARKWEFPGGKVEPGESATAALARELREELDVSVTIIEQLTPVEHRYPELSL
RLIAFRCRLTSGTPQAGAHEELRWIGIEEVADYDFPEADLPILAEYRIKNSFQ
>Mature_133_residues
MHIGDVVCAIIERDGKFLIARRPDDGRHLARKWEFPGGKVEPGESATAALARELREELDVSVTIIEQLTPVEHRYPELSL
RLIAFRCRLTSGTPQAGAHEELRWIGIEEVADYDFPEADLPILAEYRIKNSFQ

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=126, Percent_Identity=42.8571428571429, Blast_Score=88, Evalue=2e-19,
Organism=Escherichia coli, GI1786288, Length=121, Percent_Identity=29.7520661157025, Blast_Score=64, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 15095; Mature: 15095

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIGDVVCAIIERDGKFLIARRPDDGRHLARKWEFPGGKVEPGESATAALARELREELDV
CCHHHHHHEEEECCCCEEEEECCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SVTIIEQLTPVEHRYPELSLRLIAFRCRLTSGTPQAGAHEELRWIGIEEVADYDFPEADL
EEEEHHHCCCCCCCCCCHHEEEEEEEEEECCCCCCCCCCCCEEEECHHHHHCCCCCCCCC
PILAEYRIKNSFQ
CEEEEEECCCCCC
>Mature Secondary Structure
MHIGDVVCAIIERDGKFLIARRPDDGRHLARKWEFPGGKVEPGESATAALARELREELDV
CCHHHHHHEEEECCCCEEEEECCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SVTIIEQLTPVEHRYPELSLRLIAFRCRLTSGTPQAGAHEELRWIGIEEVADYDFPEADL
EEEEHHHCCCCCCCCCCHHEEEEEEEEEECCCCCCCCCCCCEEEECHHHHHCCCCCCCCC
PILAEYRIKNSFQ
CEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]