Definition Chlorobaculum parvum NCIB 8327 chromosome, complete genome.
Accession NC_011027
Length 2,289,249

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The map label for this gene is gdhII [H]

Identifier: 193212104

GI number: 193212104

Start: 469924

End: 470748

Strand: Direct

Name: gdhII [H]

Synonym: Cpar_0435

Alternate gene names: 193212104

Gene position: 469924-470748 (Clockwise)

Preceding gene: 193212103

Following gene: 193212105

Centisome position: 20.53

GC content: 56.85

Gene sequence:

>825_bases
ATGAAACAGCTCGAAAACAGGGTCGCCATCATCACCGGTTCTACCAAGGGAATCGGCCGGGCGATTGCCCATGCGTTCGT
CAAAGAGGGGGCCAAAGTGGTCATCACTTCCAGCCGCCAGGCAAATGTCGATGCCTCCCTCCGAGAGTTTCCCGATGGTT
CGGCCTGGGGCCACGTCTGCGACGTTTCCTCATACGAGGCGGTCGAGGAGCTGGTGCAGGCTTCAGTCAAACGGTTCGGC
GCCATCGACTGCTTTGTGAACAACGCCGGGATTTCCGACCCTTTCACCAGCGTCTGCGATAGCGATCCGGAAGCGTGGAG
CCGCGTGATCGACATCAACCTCAAGGGAACCTACCACGGCAGCCGCGCAGCTGCCCGCTATTTTCTGTCCTCCGGCAGGG
CGGGCAAGATCATCAACACGGCCGGATCGGGTACCGACAAGGGCTCGAATACTCCTTTTATTTCCGCCTACGGATCGACC
AAATCTGCCATCGCCCGCTTCACCTTTGCTATGGCCGAGGAGTACAAAAAGACGCCGCTCTCCATTATGCTGCTACATCC
GGGTCTGGTCAGAACCGAGATCAACCATCCGGAAGAGGCGACTCCAGAGCTGCAAAAACAGCTGAAGACCTTCAACGTGA
TTCTCGACATTTTCGCGCAGAGCCCCGATCTTGCCGCTCGTTACGCCGTGAAGATGGCCTCCTCATGGAGTGACGGCAAG
ACCGGGCAGTACCTGTCCGCGCTCGATGGAAAACGCAAGAAGATGATGCTGTTGAGCTATCCGTTTCGTAAACTGACCGG
TAGCATCGATCGAACAATTTATTGA

Upstream 100 bases:

>100_bases
GCCATCCGGAACTTCAGGCGATGATCGATCAGGCCGCCAAAAAGCAGGACTGATCGGCTTCGGCGCTCCCGGAAGCTGAC
CTGGAAATCACCACGTTGAG

Downstream 100 bases:

>100_bases
CCAATGAACGCCATGCACAAGCGAACCGGAACCCTGTTGCTTCTTTTCGGCCTGCTGACCGTTATTCTGCAAGGTTGTTA
CAGCTTTTCGGGGGCCTCGA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: GLCDH-II [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MKQLENRVAIITGSTKGIGRAIAHAFVKEGAKVVITSSRQANVDASLREFPDGSAWGHVCDVSSYEAVEELVQASVKRFG
AIDCFVNNAGISDPFTSVCDSDPEAWSRVIDINLKGTYHGSRAAARYFLSSGRAGKIINTAGSGTDKGSNTPFISAYGST
KSAIARFTFAMAEEYKKTPLSIMLLHPGLVRTEINHPEEATPELQKQLKTFNVILDIFAQSPDLAARYAVKMASSWSDGK
TGQYLSALDGKRKKMMLLSYPFRKLTGSIDRTIY

Sequences:

>Translated_274_residues
MKQLENRVAIITGSTKGIGRAIAHAFVKEGAKVVITSSRQANVDASLREFPDGSAWGHVCDVSSYEAVEELVQASVKRFG
AIDCFVNNAGISDPFTSVCDSDPEAWSRVIDINLKGTYHGSRAAARYFLSSGRAGKIINTAGSGTDKGSNTPFISAYGST
KSAIARFTFAMAEEYKKTPLSIMLLHPGLVRTEINHPEEATPELQKQLKTFNVILDIFAQSPDLAARYAVKMASSWSDGK
TGQYLSALDGKRKKMMLLSYPFRKLTGSIDRTIY
>Mature_274_residues
MKQLENRVAIITGSTKGIGRAIAHAFVKEGAKVVITSSRQANVDASLREFPDGSAWGHVCDVSSYEAVEELVQASVKRFG
AIDCFVNNAGISDPFTSVCDSDPEAWSRVIDINLKGTYHGSRAAARYFLSSGRAGKIINTAGSGTDKGSNTPFISAYGST
KSAIARFTFAMAEEYKKTPLSIMLLHPGLVRTEINHPEEATPELQKQLKTFNVILDIFAQSPDLAARYAVKMASSWSDGK
TGQYLSALDGKRKKMMLLSYPFRKLTGSIDRTIY

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=191, Percent_Identity=35.0785340314136, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI126723191, Length=190, Percent_Identity=33.6842105263158, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI5031737, Length=226, Percent_Identity=28.7610619469027, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI7705925, Length=208, Percent_Identity=30.2884615384615, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=29.8969072164948, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI59889578, Length=173, Percent_Identity=28.9017341040462, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI209862901, Length=242, Percent_Identity=26.0330578512397, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI19923983, Length=242, Percent_Identity=26.0330578512397, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=28.8557213930348, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI20149619, Length=203, Percent_Identity=28.0788177339901, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI126723750, Length=211, Percent_Identity=27.9620853080569, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI19923817, Length=200, Percent_Identity=26, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI109715829, Length=229, Percent_Identity=26.6375545851528, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI40254986, Length=185, Percent_Identity=29.1891891891892, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4758504, Length=219, Percent_Identity=26.9406392694064, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI40254992, Length=234, Percent_Identity=23.0769230769231, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI15277342, Length=211, Percent_Identity=30.3317535545024, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=28.4, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=28.968253968254, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787335, Length=197, Percent_Identity=26.3959390862944, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=30.1075268817204, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082100, Length=226, Percent_Identity=27.4336283185841, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790717, Length=195, Percent_Identity=27.6923076923077, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788459, Length=198, Percent_Identity=29.2929292929293, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI2367365, Length=197, Percent_Identity=29.4416243654822, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787526, Length=220, Percent_Identity=24.5454545454545, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=25.4980079681275, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=24.5136186770428, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=27.1317829457364, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562908, Length=223, Percent_Identity=26.457399103139, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=200, Percent_Identity=26.5, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=28.4090909090909, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=198, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=203, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=219, Percent_Identity=28.310502283105, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=217, Percent_Identity=27.1889400921659, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=223, Percent_Identity=27.8026905829596, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=205, Percent_Identity=30.7317073170732, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=202, Percent_Identity=26.7326732673267, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=202, Percent_Identity=26.7326732673267, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=200, Percent_Identity=31, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI86565303, Length=216, Percent_Identity=28.2407407407407, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=202, Percent_Identity=26.2376237623762, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555612, Length=213, Percent_Identity=28.169014084507, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=220, Percent_Identity=25, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71997099, Length=209, Percent_Identity=30.1435406698565, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=205, Percent_Identity=29.2682926829268, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=217, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=195, Percent_Identity=28.2051282051282, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=201, Percent_Identity=26.3681592039801, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=205, Percent_Identity=27.3170731707317, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=211, Percent_Identity=29.3838862559242, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=200, Percent_Identity=28.5, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17568967, Length=220, Percent_Identity=29.0909090909091, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=203, Percent_Identity=29.064039408867, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=199, Percent_Identity=26.6331658291457, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322226, Length=273, Percent_Identity=28.9377289377289, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322227, Length=255, Percent_Identity=25.8823529411765, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322861, Length=221, Percent_Identity=28.9592760180996, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=200, Percent_Identity=27, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355319, Length=195, Percent_Identity=30.2564102564103, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI23397609, Length=214, Percent_Identity=30.3738317757009, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24641232, Length=208, Percent_Identity=30.7692307692308, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17737361, Length=218, Percent_Identity=28.4403669724771, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357673, Length=203, Percent_Identity=29.5566502463054, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364494, Length=208, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21357041, Length=197, Percent_Identity=24.8730964467005, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640442, Length=232, Percent_Identity=28.0172413793103, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28571526, Length=202, Percent_Identity=26.2376237623762, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644339, Length=192, Percent_Identity=26.0416666666667, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28571387, Length=213, Percent_Identity=28.169014084507, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI18859837, Length=148, Percent_Identity=31.7567567567568, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.47 [H]

Molecular weight: Translated: 29817; Mature: 29817

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MKQLENRVAIITGSTKGIGRAIAHAFVKEGAKVVITSSRQANVDASLREFPDGSAWGHVC
CCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHCCCCCCCCCEE
DVSSYEAVEELVQASVKRFGAIDCFVNNAGISDPFTSVCDSDPEAWSRVIDINLKGTYHG
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHCCCHHHHHEEEEEEEECCCCC
SRAAARYFLSSGRAGKIINTAGSGTDKGSNTPFISAYGSTKSAIARFTFAMAEEYKKTPL
HHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCE
SIMLLHPGLVRTEINHPEEATPELQKQLKTFNVILDIFAQSPDLAARYAVKMASSWSDGK
EEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
TGQYLSALDGKRKKMMLLSYPFRKLTGSIDRTIY
CCHHHHHHCCCCCEEEEEECCHHHHCCCHHHCCC
>Mature Secondary Structure
MKQLENRVAIITGSTKGIGRAIAHAFVKEGAKVVITSSRQANVDASLREFPDGSAWGHVC
CCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHCCCCCCCCCEE
DVSSYEAVEELVQASVKRFGAIDCFVNNAGISDPFTSVCDSDPEAWSRVIDINLKGTYHG
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHCCCHHHHHEEEEEEEECCCCC
SRAAARYFLSSGRAGKIINTAGSGTDKGSNTPFISAYGSTKSAIARFTFAMAEEYKKTPL
HHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCE
SIMLLHPGLVRTEINHPEEATPELQKQLKTFNVILDIFAQSPDLAARYAVKMASSWSDGK
EEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
TGQYLSALDGKRKKMMLLSYPFRKLTGSIDRTIY
CCHHHHHHCCCCCEEEEEECCHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA