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The map label for this gene is yxbG [H]

Identifier: 193211984

GI number: 193211984

Start: 329355

End: 330161

Strand: Direct

Name: yxbG [H]

Synonym: Cpar_0311

Alternate gene names: 193211984

Gene position: 329355-330161 (Clockwise)

Preceding gene: 193211983

Following gene: 193211987

Centisome position: 14.39

GC content: 60.22

Gene sequence:

>807_bases
GTGAAAAAGCTGACCCTCTGCATAACCGGAAGCACTGACGGCATAGGCCTCGCGGCGGCGAAGCGGTTCGCTGCTGATGG
GCATCGGGTGATTGTGCATGGGCGGGATGAATCCCGAATCAGCGATGCTTGCGCGGCAATTGTCCAGTCCACGGGCGTAG
AGGCTGTTGGCTTCGTCGAGGCGGATTTTACCGATCTCGATGCGGTCTGTTCGATGGGGCGGGAGCTGGTCGAGCGCTAT
CCCGGTCTCGATCTGCTCATCAACAATGCGGCGGTGTACATGCCGACGCGGACGTTTGTGCAGGAAGGGTTCGAGACGAC
CTTCTGCGTCAACTACCTCGCGCCGGTGCTGCTGACCAGCGTCGTCAGACCGGTGCTGATTGCCAACGGCGGATCGGTGC
TGAATGTGAGTTCAATGGATCATCACAGCGCTGTGTTCGATCCCGTCAACATGCAGGGCGAGCGGAGCTATTCGGGCTAC
GAGGCCTACGCGCGGAGCAAGCTCTTCAACATCATGTTAACCATTGACTTGGCCAGCGGCGACGATGCCATACGTTCCAA
TTCGCTCGATCCCGGCGTGATCGCTACCAAGCTGCTGCACGCTGGATGGGCGCTCGCCGGTGACGACGTGTCGGTCGGAG
GCGACGATGTTTTCGAGACGGTGATGGAGATCGCGCGGAACGACTACAACGGAGAGTATTTCGAGAATGCCCGTCCCGCA
ATCTGCTCATCCGTTGCCCAAGAGCCTGTCGCTCGGCAGGAGTTGCGCGAGCTGACCGGGGAGATGCTGAGCCGGTTCGT
ACCCTGA

Upstream 100 bases:

>100_bases
ACTTCCTCTTTTTCCTGCTCGGCGTTATTTCGCTTTGGCCATTTCTGCTTGCCGGGGTGCTGCTTGTTGGGACGGTTCGT
TTTCTATGGAAGCTGAGGAA

Downstream 100 bases:

>100_bases
CTGATCGCTGGCCGCAGTTTTGCCTCAACCTTGTGGTCGAGTACCACTCCGATCCGGTCGTCAACCATTTCGCAAGCCAC
CGGTCATTCCATTGCCGGTT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MKKLTLCITGSTDGIGLAAAKRFAADGHRVIVHGRDESRISDACAAIVQSTGVEAVGFVEADFTDLDAVCSMGRELVERY
PGLDLLINNAAVYMPTRTFVQEGFETTFCVNYLAPVLLTSVVRPVLIANGGSVLNVSSMDHHSAVFDPVNMQGERSYSGY
EAYARSKLFNIMLTIDLASGDDAIRSNSLDPGVIATKLLHAGWALAGDDVSVGGDDVFETVMEIARNDYNGEYFENARPA
ICSSVAQEPVARQELRELTGEMLSRFVP

Sequences:

>Translated_268_residues
MKKLTLCITGSTDGIGLAAAKRFAADGHRVIVHGRDESRISDACAAIVQSTGVEAVGFVEADFTDLDAVCSMGRELVERY
PGLDLLINNAAVYMPTRTFVQEGFETTFCVNYLAPVLLTSVVRPVLIANGGSVLNVSSMDHHSAVFDPVNMQGERSYSGY
EAYARSKLFNIMLTIDLASGDDAIRSNSLDPGVIATKLLHAGWALAGDDVSVGGDDVFETVMEIARNDYNGEYFENARPA
ICSSVAQEPVARQELRELTGEMLSRFVP
>Mature_268_residues
MKKLTLCITGSTDGIGLAAAKRFAADGHRVIVHGRDESRISDACAAIVQSTGVEAVGFVEADFTDLDAVCSMGRELVERY
PGLDLLINNAAVYMPTRTFVQEGFETTFCVNYLAPVLLTSVVRPVLIANGGSVLNVSSMDHHSAVFDPVNMQGERSYSGY
EAYARSKLFNIMLTIDLASGDDAIRSNSLDPGVIATKLLHAGWALAGDDVSVGGDDVFETVMEIARNDYNGEYFENARPA
ICSSVAQEPVARQELRELTGEMLSRFVP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI193804850, Length=207, Percent_Identity=32.3671497584541, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI166795268, Length=195, Percent_Identity=32.3076923076923, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI186928839, Length=268, Percent_Identity=27.9850746268657, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI10190746, Length=214, Percent_Identity=31.7757009345794, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI32483357, Length=211, Percent_Identity=31.2796208530806, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI7706523, Length=210, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI225579078, Length=199, Percent_Identity=31.6582914572864, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI126723191, Length=192, Percent_Identity=32.8125, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI5031737, Length=213, Percent_Identity=28.169014084507, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787820, Length=198, Percent_Identity=23.7373737373737, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115533174, Length=181, Percent_Identity=36.4640883977901, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI115533172, Length=173, Percent_Identity=37.5722543352601, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17558006, Length=206, Percent_Identity=31.0679611650485, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=207, Percent_Identity=29.951690821256, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=210, Percent_Identity=30.4761904761905, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=223, Percent_Identity=26.9058295964126, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=205, Percent_Identity=31.7073170731707, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=207, Percent_Identity=31.8840579710145, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=202, Percent_Identity=27.7227722772277, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=202, Percent_Identity=29.7029702970297, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532805, Length=183, Percent_Identity=27.8688524590164, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=199, Percent_Identity=28.643216080402, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=224, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=211, Percent_Identity=29.3838862559242, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=202, Percent_Identity=26.7326732673267, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=197, Percent_Identity=30.4568527918782, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=202, Percent_Identity=28.2178217821782, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI19921754, Length=262, Percent_Identity=27.8625954198473, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI22024069, Length=201, Percent_Identity=31.3432835820896, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI45554248, Length=199, Percent_Identity=32.6633165829146, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640117, Length=199, Percent_Identity=32.6633165829146, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24656154, Length=202, Percent_Identity=31.1881188118812, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922628, Length=202, Percent_Identity=31.1881188118812, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24586328, Length=199, Percent_Identity=28.1407035175879, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644339, Length=203, Percent_Identity=30.5418719211823, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24643142, Length=203, Percent_Identity=29.5566502463054, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573296, Length=195, Percent_Identity=27.6923076923077, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161076371, Length=194, Percent_Identity=29.3814432989691, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21357041, Length=208, Percent_Identity=27.8846153846154, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28571526, Length=207, Percent_Identity=26.5700483091787, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28895; Mature: 28895

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLTLCITGSTDGIGLAAAKRFAADGHRVIVHGRDESRISDACAAIVQSTGVEAVGFVE
CCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEE
ADFTDLDAVCSMGRELVERYPGLDLLINNAAVYMPTRTFVQEGFETTFCVNYLAPVLLTS
CCCCCHHHHHHHHHHHHHHCCCCEEEECCEEEEECCHHHHHCCCCHHHHHHHHHHHHHHH
VVRPVLIANGGSVLNVSSMDHHSAVFDPVNMQGERSYSGYEAYARSKLFNIMLTIDLASG
HHHHHEEECCCCEEEECCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHEEEEEEEEECCC
DDAIRSNSLDPGVIATKLLHAGWALAGDDVSVGGDDVFETVMEIARNDYNGEYFENARPA
CHHHHCCCCCCHHHHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCHH
ICSSVAQEPVARQELRELTGEMLSRFVP
HHHHHHHCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKLTLCITGSTDGIGLAAAKRFAADGHRVIVHGRDESRISDACAAIVQSTGVEAVGFVE
CCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEE
ADFTDLDAVCSMGRELVERYPGLDLLINNAAVYMPTRTFVQEGFETTFCVNYLAPVLLTS
CCCCCHHHHHHHHHHHHHHCCCCEEEECCEEEEECCHHHHHCCCCHHHHHHHHHHHHHHH
VVRPVLIANGGSVLNVSSMDHHSAVFDPVNMQGERSYSGYEAYARSKLFNIMLTIDLASG
HHHHHEEECCCCEEEECCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHEEEEEEEEECCC
DDAIRSNSLDPGVIATKLLHAGWALAGDDVSVGGDDVFETVMEIARNDYNGEYFENARPA
CHHHHCCCCCCHHHHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCHH
ICSSVAQEPVARQELRELTGEMLSRFVP
HHHHHHHCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377 [H]