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The map label for this gene is slyD [C]

Identifier: 193211979

GI number: 193211979

Start: 323670

End: 324098

Strand: Direct

Name: slyD [C]

Synonym: Cpar_0306

Alternate gene names: 193211979

Gene position: 323670-324098 (Clockwise)

Preceding gene: 193211978

Following gene: 193211980

Centisome position: 14.14

GC content: 55.94

Gene sequence:

>429_bases
ATGGCACAGGTAAAACAGGGTGACAAGGTAAGGGTTCACTATACCGGAACCTACGATGATGGCACCGTTTTCGATAGCTC
GGTGGAGCGCGATCCGCTGGAGGTCACGGTCGGCACCGGCATGGTGATTCAGGGCTTCGACCGCGCACTGGTCGATATGG
AGCCGGGCCAGAAGAAAAATGTGAATATTCCGGCTGCTGAAGCCTATGGCCCGAGAGCCGAAGAGCTTGTGGCTGAAATC
CCCCGTGAGCGCATCCCCGAAAACATTCAGCTTGAAGTAGGCCAGCAGCTGCAGCTCAGCCTCGCCGATGGCGGTGAAGC
GATCGTGATGATCGTCGATCTCAGTGAAAAAACCGTCACCCTTGATGCCAACCACCCGATGGCCGGCATGGATCTGAATT
TCGAACTGGAACTGGTCGAGATTCTCTGA

Upstream 100 bases:

>100_bases
AAAATTTTTTTACGTGGGCAGTCGTGGGCTTTCGGGTCTTATCGAGTTGATGGTCTTTGTGCGGATGTCCCGATTTTAAA
TGATTCAAGGAGAACAAGTT

Downstream 100 bases:

>100_bases
TAGCTTTCGTAAGCACCGTTCCGTCCGACAGCCGTTCGAGACGGAACGGTCTTTTTTCAGTTTTACTCTTTTTCGACAAA
GCATGTTGAGTCCGGTAATC

Product: FKBP-type peptidylprolyl isomerase

Products: NA

Alternate protein names: PPIase; MtFK; Rotamase [H]

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MAQVKQGDKVRVHYTGTYDDGTVFDSSVERDPLEVTVGTGMVIQGFDRALVDMEPGQKKNVNIPAAEAYGPRAEELVAEI
PRERIPENIQLEVGQQLQLSLADGGEAIVMIVDLSEKTVTLDANHPMAGMDLNFELELVEIL

Sequences:

>Translated_142_residues
MAQVKQGDKVRVHYTGTYDDGTVFDSSVERDPLEVTVGTGMVIQGFDRALVDMEPGQKKNVNIPAAEAYGPRAEELVAEI
PRERIPENIQLEVGQQLQLSLADGGEAIVMIVDLSEKTVTLDANHPMAGMDLNFELELVEIL
>Mature_141_residues
AQVKQGDKVRVHYTGTYDDGTVFDSSVERDPLEVTVGTGMVIQGFDRALVDMEPGQKKNVNIPAAEAYGPRAEELVAEIP
RERIPENIQLEVGQQLQLSLADGGEAIVMIVDLSEKTVTLDANHPMAGMDLNFELELVEIL

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI4503727, Length=95, Percent_Identity=38.9473684210526, Blast_Score=67, Evalue=5e-12,
Organism=Homo sapiens, GI206725530, Length=72, Percent_Identity=41.6666666666667, Blast_Score=67, Evalue=7e-12,
Organism=Homo sapiens, GI17149844, Length=72, Percent_Identity=41.6666666666667, Blast_Score=67, Evalue=7e-12,
Organism=Homo sapiens, GI17149842, Length=72, Percent_Identity=41.6666666666667, Blast_Score=67, Evalue=7e-12,
Organism=Homo sapiens, GI7706131, Length=66, Percent_Identity=43.9393939393939, Blast_Score=66, Evalue=8e-12,
Organism=Homo sapiens, GI219842220, Length=66, Percent_Identity=43.9393939393939, Blast_Score=65, Evalue=2e-11,
Organism=Homo sapiens, GI33469985, Length=68, Percent_Identity=50, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1789748, Length=132, Percent_Identity=34.0909090909091, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI1786211, Length=140, Percent_Identity=26.4285714285714, Blast_Score=65, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324194, Length=70, Percent_Identity=45.7142857142857, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320727, Length=69, Percent_Identity=47.8260869565217, Blast_Score=68, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24655568, Length=88, Percent_Identity=43.1818181818182, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 15552; Mature: 15421

Theoretical pI: Translated: 4.03; Mature: 4.03

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQVKQGDKVRVHYTGTYDDGTVFDSSVERDPLEVTVGTGMVIQGFDRALVDMEPGQKKN
CCCCCCCCEEEEEEEEECCCCCEECCCCCCCCEEEEECCCEEEECCCCEEEECCCCCCCC
VNIPAAEAYGPRAEELVAEIPRERIPENIQLEVGQQLQLSLADGGEAIVMIVDLSEKTVT
CCCCCHHCCCCCHHHHHHHCCHHHCCCCEEEEECCEEEEEECCCCCEEEEEEECCCCEEE
LDANHPMAGMDLNFELELVEIL
EECCCCEECCCCCEEEEEEEEC
>Mature Secondary Structure 
AQVKQGDKVRVHYTGTYDDGTVFDSSVERDPLEVTVGTGMVIQGFDRALVDMEPGQKKN
CCCCCCCEEEEEEEEECCCCCEECCCCCCCCEEEEECCCEEEECCCCEEEECCCCCCCC
VNIPAAEAYGPRAEELVAEIPRERIPENIQLEVGQQLQLSLADGGEAIVMIVDLSEKTVT
CCCCCHHCCCCCHHHHHHHCCHHHCCCCEEEEECCEEEEEECCCCCEEEEEEECCCCEEE
LDANHPMAGMDLNFELELVEIL
EECCCCEECCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9440528 [H]