Click here to switch to the map view.

The map label for this gene is glcK [H]

Identifier: 193211906

GI number: 193211906

Start: 241406

End: 242416

Strand: Direct

Name: glcK [H]

Synonym: Cpar_0232

Alternate gene names: 193211906

Gene position: 241406-242416 (Clockwise)

Preceding gene: 193211905

Following gene: 193211907

Centisome position: 10.55

GC content: 64.0

Gene sequence:

>1011_bases
ATGCCTTCATGGGCTATCGGCATCGATCTTGGCGGGACGAACATCAAGACGGCCGTCATCGACGAGGCCGGGGGCATACT
TTTCGAGGATGCCCAGCCGACCGATAGCGCCGCGGGTCCCGATGGCGTGATCCGTCAGCTGGCGCTTCTTGCCAGCGATC
TCTACCAGCAGGCTGCCGAATCGCTCGATACCGGCGACTTCGCGGGCATCGGCGTTGGAGCGCCGGGTGCGGTCGATGCC
GTGAAGGGCACGCTCTCCTATCCTCCCAATCTTCCCGGCTGGGGATGCTATCCCTTGCGCGACCAGCTTCAGCTCCGTCT
CGAACAGGCACATGGCATCAGCGCGCCTATCCTCGTGGAAAACGACGCCAATGCTGCCGCGTATGGCGAGGCGGTCTACG
GCGGCGGCAGCGCGTTCCGCGACTTCATGCTGGTGACGCTCGGCACCGGCGTGGGCGGTGGCATCATTCTCGACCGGAAG
CTCTATCGCGGCCCGACTGGCACGGCGGGGGAGATCGGATTCATGACGATCGATTTCGAGGGGTCGAGCGTCCATGCGGG
CGTGAGGGGCACGATCGAAAGCCTGATCGGCAAGGAGCGGATCGTCGAGCTGGCATGCCGGGAGGGCGCGTCGTCCGGTC
TTTCTCCGCGTCTTCTGGAGCTGTGTGACCGTGATGTCGCCGGCCTGTCTCCACGGCATCTCGAAGAGGCGGCCAAAGAG
GGTGACCAGTTTGCGCTGCGTGTCTGGCAGCGGATCGGTACCATTCTCGGCGTCGGTCTGGCCAATGTCACGGCGCTGAT
GGACATCCGGAAGTTCGTGATTGGTGGCGGCATTTCGGCGGCTGGGGAGCTGATTTTCGAGCCAGCCCTGATGCAGCTGC
ACCGCTCCACTTTGCCATCGATGCACGACGGACTGGAGATCGTTCCGGCCAGGCTTGGCAACAAAGCCGGGATGTATGGC
GCTGCCGCGCTCTGCTTCGCTTCCGGCAAGCCGCTCAGGAGCGATGATTGA

Upstream 100 bases:

>100_bases
CGAGCAGACGCCCGAAGTGAAGGAAATTCTCGGCTTCTTCGCGTCGGGCGCGCATGGCAGGAAGTTCCTCAAGCCCTTCA
ATTCATAACCGTTTACGAGT

Downstream 100 bases:

>100_bases
GAGGCTAGCGCATTCGTTTGGTGCTCTCTCGCGTCCGCTTGGTTCACTCGCGCAATCGCTTGGAACACTTGCGCGTCCGC
TTGAGGGGCTCACGCATCTG

Product: ROK family protein

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MPSWAIGIDLGGTNIKTAVIDEAGGILFEDAQPTDSAAGPDGVIRQLALLASDLYQQAAESLDTGDFAGIGVGAPGAVDA
VKGTLSYPPNLPGWGCYPLRDQLQLRLEQAHGISAPILVENDANAAAYGEAVYGGGSAFRDFMLVTLGTGVGGGIILDRK
LYRGPTGTAGEIGFMTIDFEGSSVHAGVRGTIESLIGKERIVELACREGASSGLSPRLLELCDRDVAGLSPRHLEEAAKE
GDQFALRVWQRIGTILGVGLANVTALMDIRKFVIGGGISAAGELIFEPALMQLHRSTLPSMHDGLEIVPARLGNKAGMYG
AAALCFASGKPLRSDD

Sequences:

>Translated_336_residues
MPSWAIGIDLGGTNIKTAVIDEAGGILFEDAQPTDSAAGPDGVIRQLALLASDLYQQAAESLDTGDFAGIGVGAPGAVDA
VKGTLSYPPNLPGWGCYPLRDQLQLRLEQAHGISAPILVENDANAAAYGEAVYGGGSAFRDFMLVTLGTGVGGGIILDRK
LYRGPTGTAGEIGFMTIDFEGSSVHAGVRGTIESLIGKERIVELACREGASSGLSPRLLELCDRDVAGLSPRHLEEAAKE
GDQFALRVWQRIGTILGVGLANVTALMDIRKFVIGGGISAAGELIFEPALMQLHRSTLPSMHDGLEIVPARLGNKAGMYG
AAALCFASGKPLRSDD
>Mature_335_residues
PSWAIGIDLGGTNIKTAVIDEAGGILFEDAQPTDSAAGPDGVIRQLALLASDLYQQAAESLDTGDFAGIGVGAPGAVDAV
KGTLSYPPNLPGWGCYPLRDQLQLRLEQAHGISAPILVENDANAAAYGEAVYGGGSAFRDFMLVTLGTGVGGGIILDRKL
YRGPTGTAGEIGFMTIDFEGSSVHAGVRGTIESLIGKERIVELACREGASSGLSPRLLELCDRDVAGLSPRHLEEAAKEG
DQFALRVWQRIGTILGVGLANVTALMDIRKFVIGGGISAAGELIFEPALMQLHRSTLPSMHDGLEIVPARLGNKAGMYGA
AALCFASGKPLRSDD

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=301, Percent_Identity=26.578073089701, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI298566315, Length=301, Percent_Identity=26.578073089701, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4885285, Length=301, Percent_Identity=26.578073089701, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI190014632, Length=301, Percent_Identity=26.578073089701, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1786891, Length=333, Percent_Identity=24.9249249249249, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1787363, Length=328, Percent_Identity=28.6585365853659, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787878, Length=259, Percent_Identity=25.8687258687259, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87081733, Length=328, Percent_Identity=26.5243902439024, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 34901; Mature: 34770

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSWAIGIDLGGTNIKTAVIDEAGGILFEDAQPTDSAAGPDGVIRQLALLASDLYQQAAE
CCCEEEEEEECCCCEEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SLDTGDFAGIGVGAPGAVDAVKGTLSYPPNLPGWGCYPLRDQLQLRLEQAHGISAPILVE
HCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEE
NDANAAAYGEAVYGGGSAFRDFMLVTLGTGVGGGIILDRKLYRGPTGTAGEIGFMTIDFE
CCCCCHHCCCCEECCHHHHHHHHHHEECCCCCCCEEECCHHHCCCCCCCCCEEEEEEEEC
GSSVHAGVRGTIESLIGKERIVELACREGASSGLSPRLLELCDRDVAGLSPRHLEEAAKE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHCCCCHHHHHHHHHC
GDQFALRVWQRIGTILGVGLANVTALMDIRKFVIGGGISAAGELIFEPALMQLHRSTLPS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
MHDGLEIVPARLGNKAGMYGAAALCFASGKPLRSDD
HHCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PSWAIGIDLGGTNIKTAVIDEAGGILFEDAQPTDSAAGPDGVIRQLALLASDLYQQAAE
CCEEEEEEECCCCEEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SLDTGDFAGIGVGAPGAVDAVKGTLSYPPNLPGWGCYPLRDQLQLRLEQAHGISAPILVE
HCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEE
NDANAAAYGEAVYGGGSAFRDFMLVTLGTGVGGGIILDRKLYRGPTGTAGEIGFMTIDFE
CCCCCHHCCCCEECCHHHHHHHHHHEECCCCCCCEEECCHHHCCCCCCCCCEEEEEEEEC
GSSVHAGVRGTIESLIGKERIVELACREGASSGLSPRLLELCDRDVAGLSPRHLEEAAKE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHCCCCHHHHHHHHHC
GDQFALRVWQRIGTILGVGLANVTALMDIRKFVIGGGISAAGELIFEPALMQLHRSTLPS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
MHDGLEIVPARLGNKAGMYGAAALCFASGKPLRSDD
HHCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]