Click here to switch to the map view.

The map label for this gene is corA [H]

Identifier: 193211840

GI number: 193211840

Start: 179519

End: 180622

Strand: Direct

Name: corA [H]

Synonym: Cpar_0166

Alternate gene names: 193211840

Gene position: 179519-180622 (Clockwise)

Preceding gene: 193211839

Following gene: 193211842

Centisome position: 7.84

GC content: 54.98

Gene sequence:

>1104_bases
ATGAGCACCGGAAATCATACGCCCCACAAGAAAAGGCAGAAAAAGCGGATCTTCCGAAGCCGCGTCAAAGCGCTCGGCCA
GCCGCCGGGTTCCCTGATCCATATCGGTGAGCAGAAGGTCGAACAGACCGGCATCACGGCATTCGGCTACGATGAGGGGC
AGGCAGTTGCGGTTGAAGTAAAGAATGTCGAAGAGTGCCTTGGCTTGAAAGAGCGTTTCAAGGTGCTCTGGATCAACGTC
GATGGCTTGCATGACACCGCGGTGATCGGCATGCTCGGGGAGCTGTTCGGCATCGATTCGCTGACGCAGGAGGATATTCT
CGACACCGGGCAGCGCCCGAAGGTGGAGGATTTCGAGCGATACCTCTTTCTGTCGCTCCGGATGCTCGATTTCAACCGTG
AGCTGAACGAAATCACCCAAGAGCAGTTGAGCATCGTGCTCGGCCCCGGCTATGTCATCACTTTTCAGGAAAAGCCCGGC
GACATGTTCGAGCCCGTGCGCCAGCGCATCAGAAGCGCCGCTTCCAAACTCAGGAAGCATGATGCCGACTTTCTCGCCTA
CGCGCTCGTCGATGCGGTGGTCGATCGCTACTTCTCGATCCTCGAAGAGATCGAGAACCGCATCGATACGCTCGATTCTG
AAATGATGGCCGACTTCAGCCAGGAGGCCTTCAACGCGCTTTATGCCATGAAACGGGAGCTGATCATTTTCCGCAAAACC
GTCTGGCCATTGCGGGAGATCATCGGCAGCATCACGCGGGAGGATTTCGACGTCGTGGGCGAAGGGGTCGATCCCTATTT
CCGTGATATTTACGACCACATCGTGCAGGTGATCGACACCATCGAAGTGTTCCGCGAAATCGTTAACGGCATGCACGAAA
CCTACCTGGCCGGGGTGAACAACCGCATGAACGAAATCATGAAGTTCCTCACCATGATCGCCACGGTCTTCATGCCGCTC
TCATTTATCGCCGGCATCTATGGCATGAATTTCAAATACATGCCCGAGTTGAGCTTCCATTGGGGATACTTCACCGTACT
TGGTGTGATGGTGCTGATCGCGATCGGGTTTATGGTTTACTACCGATCGAGGAAGTGGTTCTGA

Upstream 100 bases:

>100_bases
CGTCCTGATCGTGAGCACGGGGCGCCTGGATTTTTTTTGTGCGACGGCGGGGTTACCTTTCAAAAAACGGGCTGGCTTCG
CAACGCTTACACTGTGACCG

Downstream 100 bases:

>100_bases
GCGGCGTCCTGAGGCCTATTTCTTTTTCTTGTTGCTCACAAACCAGGTCAGCCCCGCCGTGACCAGCGCGATCGCCCCGC
CAAGCCAGATCAGCTCCTGT

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSTGNHTPHKKRQKKRIFRSRVKALGQPPGSLIHIGEQKVEQTGITAFGYDEGQAVAVEVKNVEECLGLKERFKVLWINV
DGLHDTAVIGMLGELFGIDSLTQEDILDTGQRPKVEDFERYLFLSLRMLDFNRELNEITQEQLSIVLGPGYVITFQEKPG
DMFEPVRQRIRSAASKLRKHDADFLAYALVDAVVDRYFSILEEIENRIDTLDSEMMADFSQEAFNALYAMKRELIIFRKT
VWPLREIIGSITREDFDVVGEGVDPYFRDIYDHIVQVIDTIEVFREIVNGMHETYLAGVNNRMNEIMKFLTMIATVFMPL
SFIAGIYGMNFKYMPELSFHWGYFTVLGVMVLIAIGFMVYYRSRKWF

Sequences:

>Translated_367_residues
MSTGNHTPHKKRQKKRIFRSRVKALGQPPGSLIHIGEQKVEQTGITAFGYDEGQAVAVEVKNVEECLGLKERFKVLWINV
DGLHDTAVIGMLGELFGIDSLTQEDILDTGQRPKVEDFERYLFLSLRMLDFNRELNEITQEQLSIVLGPGYVITFQEKPG
DMFEPVRQRIRSAASKLRKHDADFLAYALVDAVVDRYFSILEEIENRIDTLDSEMMADFSQEAFNALYAMKRELIIFRKT
VWPLREIIGSITREDFDVVGEGVDPYFRDIYDHIVQVIDTIEVFREIVNGMHETYLAGVNNRMNEIMKFLTMIATVFMPL
SFIAGIYGMNFKYMPELSFHWGYFTVLGVMVLIAIGFMVYYRSRKWF
>Mature_366_residues
STGNHTPHKKRQKKRIFRSRVKALGQPPGSLIHIGEQKVEQTGITAFGYDEGQAVAVEVKNVEECLGLKERFKVLWINVD
GLHDTAVIGMLGELFGIDSLTQEDILDTGQRPKVEDFERYLFLSLRMLDFNRELNEITQEQLSIVLGPGYVITFQEKPGD
MFEPVRQRIRSAASKLRKHDADFLAYALVDAVVDRYFSILEEIENRIDTLDSEMMADFSQEAFNALYAMKRELIIFRKTV
WPLREIIGSITREDFDVVGEGVDPYFRDIYDHIVQVIDTIEVFREIVNGMHETYLAGVNNRMNEIMKFLTMIATVFMPLS
FIAGIYGMNFKYMPELSFHWGYFTVLGVMVLIAIGFMVYYRSRKWF

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=100, Percent_Identity=29, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324442, Length=317, Percent_Identity=24.6056782334385, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 42440; Mature: 42309

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGNHTPHKKRQKKRIFRSRVKALGQPPGSLIHIGEQKVEQTGITAFGYDEGQAVAVEV
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHCCEEEECCCCCEEEEEC
KNVEECLGLKERFKVLWINVDGLHDTAVIGMLGELFGIDSLTQEDILDTGQRPKVEDFER
CCHHHHHCHHHCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHH
YLFLSLRMLDFNRELNEITQEQLSIVLGPGYVITFQEKPGDMFEPVRQRIRSAASKLRKH
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHC
DADFLAYALVDAVVDRYFSILEEIENRIDTLDSEMMADFSQEAFNALYAMKRELIIFRKT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWPLREIIGSITREDFDVVGEGVDPYFRDIYDHIVQVIDTIEVFREIVNGMHETYLAGVN
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRMNEIMKFLTMIATVFMPLSFIAGIYGMNFKYMPELSFHWGYFTVLGVMVLIAIGFMVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHH
YRSRKWF
HHHCCCC
>Mature Secondary Structure 
STGNHTPHKKRQKKRIFRSRVKALGQPPGSLIHIGEQKVEQTGITAFGYDEGQAVAVEV
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHCCEEEECCCCCEEEEEC
KNVEECLGLKERFKVLWINVDGLHDTAVIGMLGELFGIDSLTQEDILDTGQRPKVEDFER
CCHHHHHCHHHCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHH
YLFLSLRMLDFNRELNEITQEQLSIVLGPGYVITFQEKPGDMFEPVRQRIRSAASKLRKH
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHC
DADFLAYALVDAVVDRYFSILEEIENRIDTLDSEMMADFSQEAFNALYAMKRELIIFRKT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWPLREIIGSITREDFDVVGEGVDPYFRDIYDHIVQVIDTIEVFREIVNGMHETYLAGVN
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRMNEIMKFLTMIATVFMPLSFIAGIYGMNFKYMPELSFHWGYFTVLGVMVLIAIGFMVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHH
YRSRKWF
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]