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The map label for this gene is hipA [C]

Identifier: 193211822

GI number: 193211822

Start: 161683

End: 162639

Strand: Direct

Name: hipA [C]

Synonym: Cpar_0148

Alternate gene names: 193211822

Gene position: 161683-162639 (Clockwise)

Preceding gene: 193211821

Following gene: 193211825

Centisome position: 7.06

GC content: 52.77

Gene sequence:

>957_bases
ATGGAACGGCGATGTCTCTATTGCTATGAACCGCTGGAATCCGGTGAGACGGATTTTCATCCGAAATGCAGTCGGAAAAT
GTTCGGAACGGCCACTCCGCCGCTGTTGCCTTACGACGAAAACCAGCTCGATGAGCTTGCGTTGGAGGTCGTTCGGAGCC
ATACCGCAATTACCGGCGTACAGCCCAAACTTTCGCTGCACCTGGCGTCCAACGGAAAAACCCGCTCGCCTCAACGCTTC
ACCATCGTCGGCTTGTGGGGCGGCTATATCCTCAAGCCGCCATCACCGCGCTTCCCGCAATTGCCGGAAATCGAGGATTT
GACGATGCACATGGCCGAGGAGTTGCGGATTGCAACCGTTCCGCACAGCCTGATTCGCATGAAATCGGGAACGCTGGCCT
ACCTGACTCGCCGCATCGATCGTACGAAGAAGGGAAAGCTGCACATGGAGGATATGTGCCAGATTACCGGACGTCTCACG
GAAAACAAATACGACGGTTCGTATGAGCAGATCGCAAAAGCGATCCGCCGTTTTTCGGTCAATCCGGGTTTCGATGTCAT
CAACTTTTTCGAGATGGTGCTGTTTTGCTTTCTGACCGGTAATGCCGATATGCACCTGAAAAATTTTTCCTTGATCGATA
TTCCCGAAAAAGAGGGCGTGAACCTTGCCCCGGCTTATGACCTCGTCTCCACCGCGCTCGTGATGCCATCCGACGATGAA
GAGCTTGCCCTGACGCTCAACGGCAAGAAAAAACGGCTGATGCTCACGGATTTTCAAGCAGCGTTGAAAACATTGTCGGT
TGACGAGGTGGTGCAGGATCGAGTGTTCCGGAAATTCAGCAAGGCTCGTCCAGCTCTGGAAAACCTGATTGACAAGAGTT
TCCTTGACCCGGAACTCAAGCTGGCCTACAAAGAGCTTGTCATAAAGAAATATCGGCAGATTGGGCTGGCTTCATAA

Upstream 100 bases:

>100_bases
TTGGAAAATCAATCCGCGAGATCGCATGGGGCTTTTGATGAACTGCTGCGCGGATTGCATCGGGGCGGTCAACGTGCATC
CTGTTCTTTCGGAGTAGCTT

Downstream 100 bases:

>100_bases
CTGCGTTCGCTTGCACATTCAACCCAATCCCCAAAATCATCCACAAACAAAAAAGGGCCGCCTTTTCGGGCAGCCCTTTT
TGCGTTTCTGTGCGTCCTCT

Product: HipA domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MERRCLYCYEPLESGETDFHPKCSRKMFGTATPPLLPYDENQLDELALEVVRSHTAITGVQPKLSLHLASNGKTRSPQRF
TIVGLWGGYILKPPSPRFPQLPEIEDLTMHMAEELRIATVPHSLIRMKSGTLAYLTRRIDRTKKGKLHMEDMCQITGRLT
ENKYDGSYEQIAKAIRRFSVNPGFDVINFFEMVLFCFLTGNADMHLKNFSLIDIPEKEGVNLAPAYDLVSTALVMPSDDE
ELALTLNGKKKRLMLTDFQAALKTLSVDEVVQDRVFRKFSKARPALENLIDKSFLDPELKLAYKELVIKKYRQIGLAS

Sequences:

>Translated_318_residues
MERRCLYCYEPLESGETDFHPKCSRKMFGTATPPLLPYDENQLDELALEVVRSHTAITGVQPKLSLHLASNGKTRSPQRF
TIVGLWGGYILKPPSPRFPQLPEIEDLTMHMAEELRIATVPHSLIRMKSGTLAYLTRRIDRTKKGKLHMEDMCQITGRLT
ENKYDGSYEQIAKAIRRFSVNPGFDVINFFEMVLFCFLTGNADMHLKNFSLIDIPEKEGVNLAPAYDLVSTALVMPSDDE
ELALTLNGKKKRLMLTDFQAALKTLSVDEVVQDRVFRKFSKARPALENLIDKSFLDPELKLAYKELVIKKYRQIGLAS
>Mature_318_residues
MERRCLYCYEPLESGETDFHPKCSRKMFGTATPPLLPYDENQLDELALEVVRSHTAITGVQPKLSLHLASNGKTRSPQRF
TIVGLWGGYILKPPSPRFPQLPEIEDLTMHMAEELRIATVPHSLIRMKSGTLAYLTRRIDRTKKGKLHMEDMCQITGRLT
ENKYDGSYEQIAKAIRRFSVNPGFDVINFFEMVLFCFLTGNADMHLKNFSLIDIPEKEGVNLAPAYDLVSTALVMPSDDE
ELALTLNGKKKRLMLTDFQAALKTLSVDEVVQDRVFRKFSKARPALENLIDKSFLDPELKLAYKELVIKKYRQIGLAS

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4mE [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 36203; Mature: 36203

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERRCLYCYEPLESGETDFHPKCSRKMFGTATPPLLPYDENQLDELALEVVRSHTAITGV
CCCCEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
QPKLSLHLASNGKTRSPQRFTIVGLWGGYILKPPSPRFPQLPEIEDLTMHMAEELRIATV
CCCEEEEEECCCCCCCCCEEEEEEEECCEEECCCCCCCCCCCCHHHHHHHHHHHHEEEEC
PHSLIRMKSGTLAYLTRRIDRTKKGKLHMEDMCQITGRLTENKYDGSYEQIAKAIRRFSV
CHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
NPGFDVINFFEMVLFCFLTGNADMHLKNFSLIDIPEKEGVNLAPAYDLVSTALVMPSDDE
CCCHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCCCCCCCCHHHHHHHHEECCCCCC
ELALTLNGKKKRLMLTDFQAALKTLSVDEVVQDRVFRKFSKARPALENLIDKSFLDPELK
CEEEEECCCCCEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHH
LAYKELVIKKYRQIGLAS
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MERRCLYCYEPLESGETDFHPKCSRKMFGTATPPLLPYDENQLDELALEVVRSHTAITGV
CCCCEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
QPKLSLHLASNGKTRSPQRFTIVGLWGGYILKPPSPRFPQLPEIEDLTMHMAEELRIATV
CCCEEEEEECCCCCCCCCEEEEEEEECCEEECCCCCCCCCCCCHHHHHHHHHHHHEEEEC
PHSLIRMKSGTLAYLTRRIDRTKKGKLHMEDMCQITGRLTENKYDGSYEQIAKAIRRFSV
CHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
NPGFDVINFFEMVLFCFLTGNADMHLKNFSLIDIPEKEGVNLAPAYDLVSTALVMPSDDE
CCCHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCCCCCCCCHHHHHHHHEECCCCCC
ELALTLNGKKKRLMLTDFQAALKTLSVDEVVQDRVFRKFSKARPALENLIDKSFLDPELK
CEEEEECCCCCEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHH
LAYKELVIKKYRQIGLAS
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]