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The map label for this gene is etfA [H]

Identifier: 193211778

GI number: 193211778

Start: 124490

End: 125401

Strand: Direct

Name: etfA [H]

Synonym: Cpar_0103

Alternate gene names: 193211778

Gene position: 124490-125401 (Clockwise)

Preceding gene: 193211777

Following gene: 193211779

Centisome position: 5.44

GC content: 63.27

Gene sequence:

>912_bases
ATGAAGCTGCTGCTTGTTGGCGAGTACCGCGACGGACGGCTTGCCGCCGAAACCGCTGAGCTGTTCGGATTTGCTGCCCG
GCTCGATGCAGAAGTGAGCATGGTTCTGGTTGGATCGGCTGACGATCTTCCCGCTTTCGATGGACGGTTCTATCTTGCCG
ATCTCGAAACGTATGGCGAATACCAGCCCGACGTGCATAAACGACTGGTGTTTGAGGCCATCGAAGGCGAGCAACCGGAC
GTCGTCGTTTTTCTCCACTCGTCCTATGGCTGGGATTTAGCTCCGAGGATCGCTGCTGCAATGCAGACGGCACAGGTTTC
CGGAGTCGTCGGCATCGACGATGGTGGCTACGTGGTCGAGAGCTGCAACGGCAAGATGCTCCGTACGGTGCACCCGGAGA
CGCCGGTTGCCGTGCTGACCCTTCAGCCCGGAGCGTTCGAGGCTCTGAAAATGGACGCCCAACCCGAAGTGATCAAGCTT
GACACCTCATCGGAAAGCGCGATCAAGTTCGTCGGTTGCCGTCAGCCGGAAGCGGGCGTTGATCTCACTCGCGCCGAGGT
GATCGTCAGCGCCGGGCGTGGCGTGGGCAGCGCCGATCAGGTCGCGCTGGTCGAAGCGCTCGCTTCGGCGCTCGGCGGTG
AGGTTGGCGCGAGCCGCCAGGCGGTCGATGCCGGATGGCTCGACCGAAGCCGACAGATCGGCACGAGCGGCCAGAGCGTC
TCGCCTGCACTCTACGTGGCGTGCGGCATCTCCGGCGCGATCCAGCATCTTGCCGGCATGAAAGGCTCCGGCATCGTGCT
CGCCGTCAACACCGACCGCGATGCGCCCATCGCCAGCGTGGCGGATGTACTCGTAGTGGCCGACGTGGCGGAGTTTCTGC
CCGCCCTCGTCGAGGCGCTGGAGAAACGGTGA

Upstream 100 bases:

>100_bases
CCGCCGGTGTGGTGCTGGAGGGAGATGTCCAGATGCTTGCTGTTCAGGTGCGCGAAATTCTCGAAACGAAAACCGCTGTG
CTCGGCAAGGGAGGCGCGCG

Downstream 100 bases:

>100_bases
TTTTTGTATCAACAGTAACGCAACATCGGATGAAATCAGGACACTACGCCTTCACCTATGAGATGGAGGTGCGCGACTAC
GAGTGTGACATGCAGGGCAT

Product: Electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKLLLVGEYRDGRLAAETAELFGFAARLDAEVSMVLVGSADDLPAFDGRFYLADLETYGEYQPDVHKRLVFEAIEGEQPD
VVVFLHSSYGWDLAPRIAAAMQTAQVSGVVGIDDGGYVVESCNGKMLRTVHPETPVAVLTLQPGAFEALKMDAQPEVIKL
DTSSESAIKFVGCRQPEAGVDLTRAEVIVSAGRGVGSADQVALVEALASALGGEVGASRQAVDAGWLDRSRQIGTSGQSV
SPALYVACGISGAIQHLAGMKGSGIVLAVNTDRDAPIASVADVLVVADVAEFLPALVEALEKR

Sequences:

>Translated_303_residues
MKLLLVGEYRDGRLAAETAELFGFAARLDAEVSMVLVGSADDLPAFDGRFYLADLETYGEYQPDVHKRLVFEAIEGEQPD
VVVFLHSSYGWDLAPRIAAAMQTAQVSGVVGIDDGGYVVESCNGKMLRTVHPETPVAVLTLQPGAFEALKMDAQPEVIKL
DTSSESAIKFVGCRQPEAGVDLTRAEVIVSAGRGVGSADQVALVEALASALGGEVGASRQAVDAGWLDRSRQIGTSGQSV
SPALYVACGISGAIQHLAGMKGSGIVLAVNTDRDAPIASVADVLVVADVAEFLPALVEALEKR
>Mature_303_residues
MKLLLVGEYRDGRLAAETAELFGFAARLDAEVSMVLVGSADDLPAFDGRFYLADLETYGEYQPDVHKRLVFEAIEGEQPD
VVVFLHSSYGWDLAPRIAAAMQTAQVSGVVGIDDGGYVVESCNGKMLRTVHPETPVAVLTLQPGAFEALKMDAQPEVIKL
DTSSESAIKFVGCRQPEAGVDLTRAEVIVSAGRGVGSADQVALVEALASALGGEVGASRQAVDAGWLDRSRQIGTSGQSV
SPALYVACGISGAIQHLAGMKGSGIVLAVNTDRDAPIASVADVLVVADVAEFLPALVEALEKR

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=317, Percent_Identity=34.0694006309148, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI189181759, Length=227, Percent_Identity=39.2070484581498, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI1786226, Length=174, Percent_Identity=37.3563218390805, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787990, Length=238, Percent_Identity=30.672268907563, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI87082157, Length=256, Percent_Identity=30.46875, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17506929, Length=312, Percent_Identity=33.3333333333333, Blast_Score=148, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6325261, Length=322, Percent_Identity=27.9503105590062, Blast_Score=115, Evalue=9e-27,
Organism=Drosophila melanogaster, GI17136898, Length=313, Percent_Identity=31.3099041533546, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24652801, Length=313, Percent_Identity=31.3099041533546, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31758; Mature: 31758

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLLVGEYRDGRLAAETAELFGFAARLDAEVSMVLVGSADDLPAFDGRFYLADLETYGE
CEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCEEEEEEEHHCCC
YQPDVHKRLVFEAIEGEQPDVVVFLHSSYGWDLAPRIAAAMQTAQVSGVVGIDDGGYVVE
CCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCEEEEECCCCEEEE
SCNGKMLRTVHPETPVAVLTLQPGAFEALKMDAQPEVIKLDTSSESAIKFVGCRQPEAGV
CCCCCEEEEECCCCCEEEEEECCCCCCEEECCCCCCEEEEECCCCCEEEEEECCCCCCCC
DLTRAEVIVSAGRGVGSADQVALVEALASALGGEVGASRQAVDAGWLDRSRQIGTSGQSV
CHHHHHEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
SPALYVACGISGAIQHLAGMKGSGIVLAVNTDRDAPIASVADVLVVADVAEFLPALVEAL
CCEEEEEECCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EKR
HCC
>Mature Secondary Structure
MKLLLVGEYRDGRLAAETAELFGFAARLDAEVSMVLVGSADDLPAFDGRFYLADLETYGE
CEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCEEEEEEEHHCCC
YQPDVHKRLVFEAIEGEQPDVVVFLHSSYGWDLAPRIAAAMQTAQVSGVVGIDDGGYVVE
CCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCEEEEECCCCEEEE
SCNGKMLRTVHPETPVAVLTLQPGAFEALKMDAQPEVIKLDTSSESAIKFVGCRQPEAGV
CCCCCEEEEECCCCCEEEEEECCCCCCEEECCCCCCEEEEECCCCCEEEEEECCCCCCCC
DLTRAEVIVSAGRGVGSADQVALVEALASALGGEVGASRQAVDAGWLDRSRQIGTSGQSV
CHHHHHEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
SPALYVACGISGAIQHLAGMKGSGIVLAVNTDRDAPIASVADVLVVADVAEFLPALVEAL
CCEEEEEECCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EKR
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]