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The map label for this gene is pepQ [H]

Identifier: 193211776

GI number: 193211776

Start: 122496

End: 123674

Strand: Direct

Name: pepQ [H]

Synonym: Cpar_0101

Alternate gene names: 193211776

Gene position: 122496-123674 (Clockwise)

Preceding gene: 193211775

Following gene: 193211777

Centisome position: 5.35

GC content: 59.54

Gene sequence:

>1179_bases
ATGAGACGCATGTTGGTTACTCGCACCGAAATCAAAGAACGCACCACGCGCCTGCAAGCGCGTCTTGCAGCGGGCGGCAT
GCAGGCTGCGCTGCTTCTGATGCCGTCCGACATCTATTACTTCACCGGCACGCGGCAGAACTCGGCGCTCTGGGTTCCCG
TGGAGGGCGAGCCCGTGCTGCTGGTGCGCAAAAGCCTTGAGCGCGCACGTGCCGAAGGGCTGATCGATGATATTCGCCCG
TTTCCGAAGAGCAAGGAGTTGTCCGCACTGCTCGGTGGCGAAGGCGACACGGTCGGTATGACTTTCGATGCCGTTCCGGT
GCAGCAGCATGGCTGGTATTCGAAAGTACTGCCGGGCCGCCGCTTCGTGGATTGTTCCATGATTGTCCGGGATCAGCGTT
CCGTTAAATCCCCAGCCGAGATCGAGCTGATTCGGCGGAGTGCGGACAAGCTCATTTCGGTTTTCCGGGAAGTGCCCTCA
TTCCTGAAGGCAGGTATGCGCGAGCTTGACCTTGCCGCTGAAATGGAGTACCGGTTGCGCCGTCTTGGTCACGAGGGATT
CGTGCGGATGCGGGCGTTCAATCAGGAGTTGTTCGGTGGCATGGCCGTGTCGGGCGGCGCGGCAAGCTACGGCTTTTTCG
ATGGAGCTGTTACCGGCAAAGGGTTGTCGAGCGCTGCGCCGCAGGGGGCTTCGTTTGAGGTGATCCGGGAGAATATTCCG
GTGCTTCTCGATTTTGTTGGCTTGTTCGACGGCTATCTCGTCGATATGACCCGCATGTTCGTAATCGGCAAGCTCGACGC
GGAATTGCGGCGTGCGTTCGAGGTTTCGCTTCAGATTCAGGAGGCCGTGCGCAACGCGATGGTGCCTGGAGCGATCTGCG
AGGAGGTGTATCAGCAAGCCGCTGCAATGGCTGAAGATACCGGGCTTGGTGGCAACTTTATGGGAATGCCGGGCGAGCAG
TCACGCTTTGTCGGCCACGGCGTAGGGCTCGAACTTGACGAGCTGCCGGTGCTGGCACAGGGCTTCGCCTTTCCGTTGCA
GAAGGGGCAGGTGGTGGCCGTTGAACCGAAATTCGTGTTTCCCGGCAAAGGGGCGATCGGTATCGAAAACACTTTTGCCG
TAACCGAAACGGGTGGCGAGCGGCTGACGGAACTGGCCGATGACTTGGTTCAGCTTTAA

Upstream 100 bases:

>100_bases
CGCGGATAGCCGTGAACCAATCAAGGCATACGATCTTGCCGAAATCGTCGCGCGCAGCATCGATCGAAAATGAGGGATCA
GCTGTTTTTCCAACGTTAAA

Downstream 100 bases:

>100_bases
GTTCAAGGAAATTTGTATGATGTTGTCATGAATATTCTTGTCTGTATCAAACAGGTGCCAGACATGGCCGGGCACTTCGA
ACCGAATGAGGCCGCCACCT

Product: peptidase M24

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MRRMLVTRTEIKERTTRLQARLAAGGMQAALLLMPSDIYYFTGTRQNSALWVPVEGEPVLLVRKSLERARAEGLIDDIRP
FPKSKELSALLGGEGDTVGMTFDAVPVQQHGWYSKVLPGRRFVDCSMIVRDQRSVKSPAEIELIRRSADKLISVFREVPS
FLKAGMRELDLAAEMEYRLRRLGHEGFVRMRAFNQELFGGMAVSGGAASYGFFDGAVTGKGLSSAAPQGASFEVIRENIP
VLLDFVGLFDGYLVDMTRMFVIGKLDAELRRAFEVSLQIQEAVRNAMVPGAICEEVYQQAAAMAEDTGLGGNFMGMPGEQ
SRFVGHGVGLELDELPVLAQGFAFPLQKGQVVAVEPKFVFPGKGAIGIENTFAVTETGGERLTELADDLVQL

Sequences:

>Translated_392_residues
MRRMLVTRTEIKERTTRLQARLAAGGMQAALLLMPSDIYYFTGTRQNSALWVPVEGEPVLLVRKSLERARAEGLIDDIRP
FPKSKELSALLGGEGDTVGMTFDAVPVQQHGWYSKVLPGRRFVDCSMIVRDQRSVKSPAEIELIRRSADKLISVFREVPS
FLKAGMRELDLAAEMEYRLRRLGHEGFVRMRAFNQELFGGMAVSGGAASYGFFDGAVTGKGLSSAAPQGASFEVIRENIP
VLLDFVGLFDGYLVDMTRMFVIGKLDAELRRAFEVSLQIQEAVRNAMVPGAICEEVYQQAAAMAEDTGLGGNFMGMPGEQ
SRFVGHGVGLELDELPVLAQGFAFPLQKGQVVAVEPKFVFPGKGAIGIENTFAVTETGGERLTELADDLVQL
>Mature_392_residues
MRRMLVTRTEIKERTTRLQARLAAGGMQAALLLMPSDIYYFTGTRQNSALWVPVEGEPVLLVRKSLERARAEGLIDDIRP
FPKSKELSALLGGEGDTVGMTFDAVPVQQHGWYSKVLPGRRFVDCSMIVRDQRSVKSPAEIELIRRSADKLISVFREVPS
FLKAGMRELDLAAEMEYRLRRLGHEGFVRMRAFNQELFGGMAVSGGAASYGFFDGAVTGKGLSSAAPQGASFEVIRENIP
VLLDFVGLFDGYLVDMTRMFVIGKLDAELRRAFEVSLQIQEAVRNAMVPGAICEEVYQQAAAMAEDTGLGGNFMGMPGEQ
SRFVGHGVGLELDELPVLAQGFAFPLQKGQVVAVEPKFVFPGKGAIGIENTFAVTETGGERLTELADDLVQL

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=256, Percent_Identity=29.6875, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 42935; Mature: 42935

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRMLVTRTEIKERTTRLQARLAAGGMQAALLLMPSDIYYFTGTRQNSALWVPVEGEPVL
CCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCCCCEEEEEECCCCEE
LVRKSLERARAEGLIDDIRPFPKSKELSALLGGEGDTVGMTFDAVPVQQHGWYSKVLPGR
HHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHCCCCCEEEEEEECCCCHHCCCHHHCCCCC
RFVDCSMIVRDQRSVKSPAEIELIRRSADKLISVFREVPSFLKAGMRELDLAAEMEYRLR
CEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLGHEGFVRMRAFNQELFGGMAVSGGAASYGFFDGAVTGKGLSSAAPQGASFEVIRENIP
HCCHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCH
VLLDFVGLFDGYLVDMTRMFVIGKLDAELRRAFEVSLQIQEAVRNAMVPGAICEEVYQQA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AAMAEDTGLGGNFMGMPGEQSRFVGHGVGLELDELPVLAQGFAFPLQKGQVVAVEPKFVF
HHHHHCCCCCCCCCCCCCCCCCEEECCCCCCHHCCCHHHHCCCCCCCCCCEEEECCEEEE
PGKGAIGIENTFAVTETGGERLTELADDLVQL
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRRMLVTRTEIKERTTRLQARLAAGGMQAALLLMPSDIYYFTGTRQNSALWVPVEGEPVL
CCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCCCCEEEEEECCCCEE
LVRKSLERARAEGLIDDIRPFPKSKELSALLGGEGDTVGMTFDAVPVQQHGWYSKVLPGR
HHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHCCCCCEEEEEEECCCCHHCCCHHHCCCCC
RFVDCSMIVRDQRSVKSPAEIELIRRSADKLISVFREVPSFLKAGMRELDLAAEMEYRLR
CEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLGHEGFVRMRAFNQELFGGMAVSGGAASYGFFDGAVTGKGLSSAAPQGASFEVIRENIP
HCCHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCH
VLLDFVGLFDGYLVDMTRMFVIGKLDAELRRAFEVSLQIQEAVRNAMVPGAICEEVYQQA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AAMAEDTGLGGNFMGMPGEQSRFVGHGVGLELDELPVLAQGFAFPLQKGQVVAVEPKFVF
HHHHHCCCCCCCCCCCCCCCCCEEECCCCCCHHCCCHHHHCCCCCCCCCCEEEECCEEEE
PGKGAIGIENTFAVTETGGERLTELADDLVQL
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]