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The map label for this gene is surE

Identifier: 192291556

GI number: 192291556

Start: 3428249

End: 3429016

Strand: Reverse

Name: surE

Synonym: Rpal_3182

Alternate gene names: 192291556

Gene position: 3429016-3428249 (Counterclockwise)

Preceding gene: 192291557

Following gene: 192291555

Centisome position: 59.7

GC content: 66.02

Gene sequence:

>768_bases
ATGCGGATTCTGTGCACCAACGACGACGGCATTCATGCGCCCGGCCTGAAGACGGTCGAACAGATCGCCCGCGCGATCTC
CGACGACGTCTGGGTGGTGGCGCCCGAGCTCGACCAGTCCGGGGTGTCGCATTCGCTGTCGCTGAACGATCCGCTGCGCC
TGCGCGAAGTCGGCCCGCGGCACTTTGCGGTGCGCGGCACGCCGACCGACTGCGTGATCATGGGCTCGCGCTTCATCCTC
AAGGACAAGGCGCCGGATCTGGTGCTGTCGGGCGTCAACCGCGGCCGTAACGTCGCCGAGGACGTGGTCTATTCCGGCAC
CATCGCAGGCGCGCTGGAAGGCACCATCCTCGGCCTGCCGTCGTTCGCGCTGTCGCAGGAATTCACCATCGAGACTCGCA
ACGCGCCGCTGTGGGAGACCGCGCGGACTCACGCGCCCGACATCATCCGCAAGGTGATGGCCGCAGGCGTGCCGAAGAAC
ACCGTGGTCAACATCAACTTTCCGGCCTGCACGCCCGACAAGGTCAAGGGCGTGGTGGTGACGCGGCAGGGCAAGCGCAA
TCCCGGCTTCCTGCGCATCGACGAACGCCACGACGGCCGCGGCAATCCGTATTACTGGATCGGCTTCGAAAGGATCAAAG
TCGAAGACATGCCGGCCGAAGGCACCGATCTGGCCGCGCTCGCCGCCAACTTCGTCTCGGTGACGCCGCTCAAGCTCGAC
CGTACCGACGAGACGTTTTCGGCGGCGCTGGCCAATACGCTGGCGTGA

Upstream 100 bases:

>100_bases
CCGGCCGATCCGGCCGGGCTTGGGCCGAATTTGCCTCTCGCGGCCGGGCCGGATATGACGACGGCCTCAAGAAAGACCTT
CAGAGAGGCAGCCCAGCGAC

Downstream 100 bases:

>100_bases
AGCTGACTGCGTAGGATGGTAGAGCGTTAGCGAGACCCATCTAGGGGGCACCCGAGGTTGATGGGGCGCGGCGTTCAATG
TCGCAGGGCTGAGCGGTAGC

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MRILCTNDDGIHAPGLKTVEQIARAISDDVWVVAPELDQSGVSHSLSLNDPLRLREVGPRHFAVRGTPTDCVIMGSRFIL
KDKAPDLVLSGVNRGRNVAEDVVYSGTIAGALEGTILGLPSFALSQEFTIETRNAPLWETARTHAPDIIRKVMAAGVPKN
TVVNINFPACTPDKVKGVVVTRQGKRNPGFLRIDERHDGRGNPYYWIGFERIKVEDMPAEGTDLAALAANFVSVTPLKLD
RTDETFSAALANTLA

Sequences:

>Translated_255_residues
MRILCTNDDGIHAPGLKTVEQIARAISDDVWVVAPELDQSGVSHSLSLNDPLRLREVGPRHFAVRGTPTDCVIMGSRFIL
KDKAPDLVLSGVNRGRNVAEDVVYSGTIAGALEGTILGLPSFALSQEFTIETRNAPLWETARTHAPDIIRKVMAAGVPKN
TVVNINFPACTPDKVKGVVVTRQGKRNPGFLRIDERHDGRGNPYYWIGFERIKVEDMPAEGTDLAALAANFVSVTPLKLD
RTDETFSAALANTLA
>Mature_255_residues
MRILCTNDDGIHAPGLKTVEQIARAISDDVWVVAPELDQSGVSHSLSLNDPLRLREVGPRHFAVRGTPTDCVIMGSRFIL
KDKAPDLVLSGVNRGRNVAEDVVYSGTIAGALEGTILGLPSFALSQEFTIETRNAPLWETARTHAPDIIRKVMAAGVPKN
TVVNINFPACTPDKVKGVVVTRQGKRNPGFLRIDERHDGRGNPYYWIGFERIKVEDMPAEGTDLAALAANFVSVTPLKLD
RTDETFSAALANTLA

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=255, Percent_Identity=40, Blast_Score=167, Evalue=8e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_RHOPA (Q6N5X7)

Other databases:

- EMBL:   BX572602
- RefSeq:   NP_948184.1
- ProteinModelPortal:   Q6N5X7
- SMR:   Q6N5X7
- GeneID:   2693191
- GenomeReviews:   BX571963_GR
- KEGG:   rpa:RPA2841
- NMPDR:   fig|258594.1.peg.2827
- HOGENOM:   HBG600532
- OMA:   PACAPDE
- ProtClustDB:   PRK00346
- BioCyc:   RPAL258594:RPA2841-MONOMER
- BRENDA:   3.1.3.5
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 27695; Mature: 27695

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILCTNDDGIHAPGLKTVEQIARAISDDVWVVAPELDQSGVSHSLSLNDPLRLREVGPR
CEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCEEECCCCCCHHEECCCC
HFAVRGTPTDCVIMGSRFILKDKAPDLVLSGVNRGRNVAEDVVYSGTIAGALEGTILGLP
EEEEECCCCCEEEECCEEEEECCCCCCEEECCCCCCCHHHHHHCCCEEHHHHCCEEEECC
SFALSQEFTIETRNAPLWETARTHAPDIIRKVMAAGVPKNTVVNINFPACTPDKVKGVVV
CHHCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEE
TRQGKRNPGFLRIDERHDGRGNPYYWIGFERIKVEDMPAEGTDLAALAANFVSVTPLKLD
EECCCCCCCEEEEECCCCCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHEECEEEEC
RTDETFSAALANTLA
CCCHHHHHHHHHHCC
>Mature Secondary Structure
MRILCTNDDGIHAPGLKTVEQIARAISDDVWVVAPELDQSGVSHSLSLNDPLRLREVGPR
CEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCEEECCCCCCHHEECCCC
HFAVRGTPTDCVIMGSRFILKDKAPDLVLSGVNRGRNVAEDVVYSGTIAGALEGTILGLP
EEEEECCCCCEEEECCEEEEECCCCCCEEECCCCCCCHHHHHHCCCEEHHHHCCEEEECC
SFALSQEFTIETRNAPLWETARTHAPDIIRKVMAAGVPKNTVVNINFPACTPDKVKGVVV
CHHCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEE
TRQGKRNPGFLRIDERHDGRGNPYYWIGFERIKVEDMPAEGTDLAALAANFVSVTPLKLD
EECCCCCCCEEEEECCCCCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHEECEEEEC
RTDETFSAALANTLA
CCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA