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The map label for this gene is appC [H]

Identifier: 192291294

GI number: 192291294

Start: 3183197

End: 3184027

Strand: Reverse

Name: appC [H]

Synonym: Rpal_2916

Alternate gene names: 192291294

Gene position: 3184027-3183197 (Counterclockwise)

Preceding gene: 192291295

Following gene: 192291293

Centisome position: 55.43

GC content: 64.38

Gene sequence:

>831_bases
GTGGATACGCTCAAACGCTACTTCCGCAGCCCGGCCGCTATCGTCGGCCTGATCCTGTTGCTGCTGATCATTGGCATGGC
GATCAGCGCCGGCTGGATCTATCCGCGCGACCCCTTGGCGTTGGCCGGCCGCCCCCTGATCTGGCCATTCAGTAATCCGC
GTTTCTTGCTCGGCACCGACAACTCCGGCCGCGACATAGCCGCCCAGATCTTCCATGGTGCGCGGATCGCGCTGCTGATC
GGCGGCGCCGCCACGGTGATCGCAATTCTGATCGGAGTGCTGATCGGCGCGTTCGCGGGCTATTTCGGCGGCTGGGTCGA
CACTGTCCTGATGCGAATTACAGAGGCATTCCAGACTCTGCCGAACTTTGTGCTGCTGCTGGTGCTGGTCGCGGTGTTCG
GTTCGACGCTGACCACGGTCACAATCGCGGTCGGCATCGTGTCGTGGCCGGCGCCGGCACGGCTAACGCGTGCCGAATTC
CTCAGCCTGCGCAATCGTGAATTCGTGCAAGCAGGCCGAACGCTGGGCATGAAGGACCTGCAACTGATCCTCGGCGAGAT
CCTGCCCAACGCGCTGCCGCCGGTGATCGTCTATGCCAGCGTGGTGATGGCGGTGGCGATCCTGCTCGAGAGCGCGCTGG
CCTTCCTGCGTCTGTCCGATCCGAATGTCGCCTCTTGGGGCAATCTGATCGGGCTCGGCCGCGACGTGTTGCGCGTGCAG
TGGTACGTCGCCGCGATCCCCGGCATCGCCATTTTGATCACCGTGCTGGCGGTGTCGCTGGTCGGCCAGGGCCTCAACGA
CGCGCTCAACCCGAGGCTGAAGGGCCGATGA

Upstream 100 bases:

>100_bases
TATCGTATTCGTCTCGGCGCTCCTGGTGATCGCCGTCAACTTCCTGGTCGACCTGCTCTACGCCCGCCTCGACCCGCGCA
TCTCGGCGGGGGCTTGACGC

Downstream 100 bases:

>100_bases
CCGCGCCCGCAGTTCTCACGCTCGACAAAGTCAGCGTCCGGCTGCCCGCCGGCGCCGACCGCAGCCATGCCGTGCGCGAC
GCATCGCTGACGATCGCCGC

Product: ABC transporter inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MDTLKRYFRSPAAIVGLILLLLIIGMAISAGWIYPRDPLALAGRPLIWPFSNPRFLLGTDNSGRDIAAQIFHGARIALLI
GGAATVIAILIGVLIGAFAGYFGGWVDTVLMRITEAFQTLPNFVLLLVLVAVFGSTLTTVTIAVGIVSWPAPARLTRAEF
LSLRNREFVQAGRTLGMKDLQLILGEILPNALPPVIVYASVVMAVAILLESALAFLRLSDPNVASWGNLIGLGRDVLRVQ
WYVAAIPGIAILITVLAVSLVGQGLNDALNPRLKGR

Sequences:

>Translated_276_residues
MDTLKRYFRSPAAIVGLILLLLIIGMAISAGWIYPRDPLALAGRPLIWPFSNPRFLLGTDNSGRDIAAQIFHGARIALLI
GGAATVIAILIGVLIGAFAGYFGGWVDTVLMRITEAFQTLPNFVLLLVLVAVFGSTLTTVTIAVGIVSWPAPARLTRAEF
LSLRNREFVQAGRTLGMKDLQLILGEILPNALPPVIVYASVVMAVAILLESALAFLRLSDPNVASWGNLIGLGRDVLRVQ
WYVAAIPGIAILITVLAVSLVGQGLNDALNPRLKGR
>Mature_276_residues
MDTLKRYFRSPAAIVGLILLLLIIGMAISAGWIYPRDPLALAGRPLIWPFSNPRFLLGTDNSGRDIAAQIFHGARIALLI
GGAATVIAILIGVLIGAFAGYFGGWVDTVLMRITEAFQTLPNFVLLLVLVAVFGSTLTTVTIAVGIVSWPAPARLTRAEF
LSLRNREFVQAGRTLGMKDLQLILGEILPNALPPVIVYASVVMAVAILLESALAFLRLSDPNVASWGNLIGLGRDVLRVQ
WYVAAIPGIAILITVLAVSLVGQGLNDALNPRLKGR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=272, Percent_Identity=35.2941176470588, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1787760, Length=268, Percent_Identity=34.7014925373134, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1789964, Length=276, Percent_Identity=39.8550724637681, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787498, Length=276, Percent_Identity=34.0579710144928, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1789889, Length=248, Percent_Identity=33.8709677419355, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788505, Length=229, Percent_Identity=31.4410480349345, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1787549, Length=273, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29526; Mature: 29526

Theoretical pI: Translated: 10.80; Mature: 10.80

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLKRYFRSPAAIVGLILLLLIIGMAISAGWIYPRDPLALAGRPLIWPFSNPRFLLGTD
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEECCCCCEEEEECC
NSGRDIAAQIFHGARIALLIGGAATVIAILIGVLIGAFAGYFGGWVDTVLMRITEAFQTL
CCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PNFVLLLVLVAVFGSTLTTVTIAVGIVSWPAPARLTRAEFLSLRNREFVQAGRTLGMKDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QLILGEILPNALPPVIVYASVVMAVAILLESALAFLRLSDPNVASWGNLIGLGRDVLRVQ
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHH
WYVAAIPGIAILITVLAVSLVGQGLNDALNPRLKGR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCC
>Mature Secondary Structure
MDTLKRYFRSPAAIVGLILLLLIIGMAISAGWIYPRDPLALAGRPLIWPFSNPRFLLGTD
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEECCCCCEEEEECC
NSGRDIAAQIFHGARIALLIGGAATVIAILIGVLIGAFAGYFGGWVDTVLMRITEAFQTL
CCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PNFVLLLVLVAVFGSTLTTVTIAVGIVSWPAPARLTRAEFLSLRNREFVQAGRTLGMKDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QLILGEILPNALPPVIVYASVVMAVAILLESALAFLRLSDPNVASWGNLIGLGRDVLRVQ
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHH
WYVAAIPGIAILITVLAVSLVGQGLNDALNPRLKGR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]