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The map label for this gene is cfa [H]

Identifier: 192291216

GI number: 192291216

Start: 3090066

End: 3091295

Strand: Reverse

Name: cfa [H]

Synonym: Rpal_2838

Alternate gene names: 192291216

Gene position: 3091295-3090066 (Counterclockwise)

Preceding gene: 192291217

Following gene: 192291215

Centisome position: 53.82

GC content: 63.41

Gene sequence:

>1230_bases
ATGTCCGAGTTGGTAGCGCTGACCCCCGACAACGTCGATGACCGTGTGGCCGATCTGCCGCGCGTGGTGCGGATGGCGCT
GGCGTTCGGTGCGCGGCTGCAGCGCGGAACGCTCGACGTCACCCTGCCCGACGGCCGCCGCTTCCGCCTCGGCGGCGCCG
AGCCCGGCCCCGCCGCCGAGATGCGGCTGCACAGCTACGGCTTTGCGTCGCGGCTGATCCATGGCGGCGACATCGGTATC
GCCGAGGCTTACCTGAACCGCGAGTGGGACACGCCCGATCTCACCCAGTTCCTGTACCTGTTCTGCGTCAACCACGAGAT
GATTCAGGCGATGCTGGCGGACAATCCGCTGATGCGGCTGGTGCAGATGGTGCGGCACTGGTTCAACCGCAACACCAAGC
GGCAGGCACGCAAGAACATCTACGCCCATTACGACATCGGCAACGAGTTCTACTCCGCCTGGCTCGATCCGAGCATGACG
TATTCGTCGGCGCTGTTCGAAGACCACACCCACGATCTGACCGCGGCGCAGATCAACAAATATCAGCGGCTCGCCGAGGC
GATCGACCTCAAGCCGGGACAGTCGGTGCTGGAGATCGGCTGCGGCTGGGGCGGCTTTGCGGAATATGCCGCTAAGACCT
TCGACGTCCGCCTCGTCGGCCTGACGATCAGCCGGGAACAGCGGGATTTTGCGCAGCAGCGGATGTTCGAGGCCGGACTC
GCCGACAAGGTCGAGATCAAGCTGCAGGACTACCGCGACGAGCGCGGCCGCTACGACCGGATCGCCTCGATCGAGATGAT
CGAAGCGGTCGGCGAGGAATTCTGGCCAAAATACTTCTCGCAGTTGCGCGATCGGCTAATGCCGGGAGGACTGGTCGGTA
TCCAGGCCATCACCATCCAGGACCGGTTCTTCCAGACCTACCGCCGAGAGGTCGATTTCATCCAGCGCTACGTGTTCCCC
GGCGGCATGCTGCCCTCACCCGGCGTGCTGAAATCGCTCGGCGAGACGTTCGGCGTGCCTGTGGTGCGTGAGCGCGTGTT
TGGAGAAGATTATGCCAAGACGCTCGCAACCTGGAGAGACAATTTCCGTGCAGCGTGGCCGAAGCTGAGATCGCAAGGCT
TCGACGACCGCTTCCGCCGGCTGTGGGAATACTACCTGTCGTATTGCGAAGCCGGTTTCCTATCCGGAAACATCGACGTC
CGCCAGGTGGTGTTCGCAAAGGCGGGCTGA

Upstream 100 bases:

>100_bases
CCGGCTTTGCAGCCGGCGGTCACGATGCTTATACTCACTAAAGCTAAAGTATGAGCCCGGCGTTGCTCCCGTTGCGCTGG
GCGCAAGCAATGGAACAGTA

Downstream 100 bases:

>100_bases
TCCTGTTGCGGTCTTGCTGCCGCGTTCGCTCATGCGGCAGAAGGCGTGCCTTGTCTCGTGCCGTCCGGTCTCTTAACTTG
AGGGCCCGCAACGTCACCAG

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MSELVALTPDNVDDRVADLPRVVRMALAFGARLQRGTLDVTLPDGRRFRLGGAEPGPAAEMRLHSYGFASRLIHGGDIGI
AEAYLNREWDTPDLTQFLYLFCVNHEMIQAMLADNPLMRLVQMVRHWFNRNTKRQARKNIYAHYDIGNEFYSAWLDPSMT
YSSALFEDHTHDLTAAQINKYQRLAEAIDLKPGQSVLEIGCGWGGFAEYAAKTFDVRLVGLTISREQRDFAQQRMFEAGL
ADKVEIKLQDYRDERGRYDRIASIEMIEAVGEEFWPKYFSQLRDRLMPGGLVGIQAITIQDRFFQTYRREVDFIQRYVFP
GGMLPSPGVLKSLGETFGVPVVRERVFGEDYAKTLATWRDNFRAAWPKLRSQGFDDRFRRLWEYYLSYCEAGFLSGNIDV
RQVVFAKAG

Sequences:

>Translated_409_residues
MSELVALTPDNVDDRVADLPRVVRMALAFGARLQRGTLDVTLPDGRRFRLGGAEPGPAAEMRLHSYGFASRLIHGGDIGI
AEAYLNREWDTPDLTQFLYLFCVNHEMIQAMLADNPLMRLVQMVRHWFNRNTKRQARKNIYAHYDIGNEFYSAWLDPSMT
YSSALFEDHTHDLTAAQINKYQRLAEAIDLKPGQSVLEIGCGWGGFAEYAAKTFDVRLVGLTISREQRDFAQQRMFEAGL
ADKVEIKLQDYRDERGRYDRIASIEMIEAVGEEFWPKYFSQLRDRLMPGGLVGIQAITIQDRFFQTYRREVDFIQRYVFP
GGMLPSPGVLKSLGETFGVPVVRERVFGEDYAKTLATWRDNFRAAWPKLRSQGFDDRFRRLWEYYLSYCEAGFLSGNIDV
RQVVFAKAG
>Mature_408_residues
SELVALTPDNVDDRVADLPRVVRMALAFGARLQRGTLDVTLPDGRRFRLGGAEPGPAAEMRLHSYGFASRLIHGGDIGIA
EAYLNREWDTPDLTQFLYLFCVNHEMIQAMLADNPLMRLVQMVRHWFNRNTKRQARKNIYAHYDIGNEFYSAWLDPSMTY
SSALFEDHTHDLTAAQINKYQRLAEAIDLKPGQSVLEIGCGWGGFAEYAAKTFDVRLVGLTISREQRDFAQQRMFEAGLA
DKVEIKLQDYRDERGRYDRIASIEMIEAVGEEFWPKYFSQLRDRLMPGGLVGIQAITIQDRFFQTYRREVDFIQRYVFPG
GMLPSPGVLKSLGETFGVPVVRERVFGEDYAKTLATWRDNFRAAWPKLRSQGFDDRFRRLWEYYLSYCEAGFLSGNIDVR
QVVFAKAG

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=385, Percent_Identity=34.5454545454545, Blast_Score=206, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI133904226, Length=428, Percent_Identity=34.5794392523364, Blast_Score=241, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 47015; Mature: 46884

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELVALTPDNVDDRVADLPRVVRMALAFGARLQRGTLDVTLPDGRRFRLGGAEPGPAAE
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCCCHHH
MRLHSYGFASRLIHGGDIGIAEAYLNREWDTPDLTQFLYLFCVNHEMIQAMLADNPLMRL
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
VQMVRHWFNRNTKRQARKNIYAHYDIGNEFYSAWLDPSMTYSSALFEDHTHDLTAAQINK
HHHHHHHHCCCHHHHHHHCCEEEEECCHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHH
YQRLAEAIDLKPGQSVLEIGCGWGGFAEYAAKTFDVRLVGLTISREQRDFAQQRMFEAGL
HHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHEEEEEEEEECHHHHHHHHHHHHHCCC
ADKVEIKLQDYRDERGRYDRIASIEMIEAVGEEFWPKYFSQLRDRLMPGGLVGIQAITIQ
CCEEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHH
DRFFQTYRREVDFIQRYVFPGGMLPSPGVLKSLGETFGVPVVRERVFGEDYAKTLATWRD
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHH
NFRAAWPKLRSQGFDDRFRRLWEYYLSYCEAGFLSGNIDVRQVVFAKAG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEECCC
>Mature Secondary Structure 
SELVALTPDNVDDRVADLPRVVRMALAFGARLQRGTLDVTLPDGRRFRLGGAEPGPAAE
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCCCHHH
MRLHSYGFASRLIHGGDIGIAEAYLNREWDTPDLTQFLYLFCVNHEMIQAMLADNPLMRL
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
VQMVRHWFNRNTKRQARKNIYAHYDIGNEFYSAWLDPSMTYSSALFEDHTHDLTAAQINK
HHHHHHHHCCCHHHHHHHCCEEEEECCHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHH
YQRLAEAIDLKPGQSVLEIGCGWGGFAEYAAKTFDVRLVGLTISREQRDFAQQRMFEAGL
HHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHEEEEEEEEECHHHHHHHHHHHHHCCC
ADKVEIKLQDYRDERGRYDRIASIEMIEAVGEEFWPKYFSQLRDRLMPGGLVGIQAITIQ
CCEEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHH
DRFFQTYRREVDFIQRYVFPGGMLPSPGVLKSLGETFGVPVVRERVFGEDYAKTLATWRD
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHH
NFRAAWPKLRSQGFDDRFRRLWEYYLSYCEAGFLSGNIDVRQVVFAKAG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]