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The map label for this gene is cph1 [H]

Identifier: 192291091

GI number: 192291091

Start: 2943621

End: 2945153

Strand: Reverse

Name: cph1 [H]

Synonym: Rpal_2712

Alternate gene names: 192291091

Gene position: 2945153-2943621 (Counterclockwise)

Preceding gene: 192291092

Following gene: 192291090

Centisome position: 51.27

GC content: 64.58

Gene sequence:

>1533_bases
GTGACTCCTGAATCCGCGCGCAAGCGATCGCTTGCCCAGGTCACACTGCTGTCGCTGTCGTTCGCCGTGCTGGTCGCGAT
CAGCCTGGCGTCGGTGTACTGGCTGCAGAAGGCGCGCGAGGACAACGCCTGGGTTGCCCATACCCTCGAAGTCCAGAACC
AAATCGCGCTGGCACAGCTGCAATTGCGCCGTGCCGAAAGCGCCGAACGCGGCTACGTCCTGACCCAGCAGGACGATTTG
ATCGCCCAGTTCGAGGAGGCGGCGTCCGATGTCGTGCCGCGGCTGAAGAAGCTACGGGATTTCGTCGCCGACAATACCGC
GCAGGTCCCGTTCATCGACCAGGCGATAGCCTCCGCCAACTCACGCATCGAACGGTTTCGCCAGGTGATCGCGCTGGCGC
AGCAGGGCCGGATCGAGGACGCCCGGCAATTGCTGCGCGACACCGACGGCCGCCGTGCCATGGACACCCTCACCACGTCG
CTGACGGCAATGCGCCAGGAGGAAAACCGGCTGTTTTCCGAGCGCACCACCGAGGCCGACCGCAGCCAGGCGCTGGCCAC
CATCATCACCACCACCGGTTCGGGATTGGTTCTGGTGCTAGCCGGCCTGTCGATCTTCCTGGTGCGACGCTCGGCGCGGG
CGCGCGACGAAGCCGAAAATCAGCTGCGCGAGAACAATCTGAACCTGGAATCCGCCGTGCAGGAGCGGACCGCCGACCTG
CGCGAGGCCAACGAGGAGATCCAGCGCTTCGCCTACATCGTCAGCCACGATCTGCGCTCGCCGCTGGTCAACATCATGGG
CTTCACCAGCGAGCTGGAAGAGCTGCGCAGCGACATCTTCCGCCGGATCGGGACGCTGAGCCGCGAAGTCACGGGCAAGC
AGAGCGCCGCCAATGCCGACGGCGATGGCGAGGCGGAACTCGAGCCCGCCGACCGCCAGCTCTCCGAGGATTTCACCGAG
GCGCTCGGCTTCATCAAATCCTCGATCGGCAAGATGGACCGCCTGATCAGCGCCATCCTGAATCTGACCCGCGAAGGCCG
GCGCCAATTTCAGCCGGTGCGGATCGAGACCCGCGAGTTGATCGAGAACATCGTCTCCACCGTCGCGCACCAGGCCGCCG
AAGCCAACGCCCAGATCCGCATCGAGCCCTTGCCGGAGATCGTCAGCGACCGCCTCGCGCTTGAACAGATCTTCTCAAAT
CTCATCGATAACGCCCTGAAATATCTCAAGGATGGCGTACCGGGCGACATCGTGATCCGCGGCCGCCAGAAGCTCGGCTT
CGTGATCTTCGAGATCGCCGACAACGGCCGGGGGATCGATCCCAAGGACCACCAGAGAATCTTTGATCTTTTCCGCCGCG
CCGGTACACAGGATCGGCCCGGCCAAGGGATCGGCCTCGCCCATGTGCGAGCGCTGGTCCGACGCCTGGGCGGCACCATG
TCGGTGTCATCCGCGCTCGGCGAAGGCTCGACCTTCACCATCACCCTGCCGGCCAAGTGGACGGCAAACAAGAACCAGGA
ACAGCGCGCATGA

Upstream 100 bases:

>100_bases
GGAACCTTTCCGTTTCACCGACGTTAGAAGGCGTTCTGAGTTCTGCCTTGCGACGCCTGGGGGATGGCTTGCTTGATTTC
GTTCGTGCTGGAGGCGCGCG

Downstream 100 bases:

>100_bases
GTAACCCTGTCACCATCATCATGATCGAGGACGACGAGGGTCATGCCCGTCTGATCGAGCGGAACATCCGCCGTTCGGGC
GTCAACAACGAGATCATCCC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MTPESARKRSLAQVTLLSLSFAVLVAISLASVYWLQKAREDNAWVAHTLEVQNQIALAQLQLRRAESAERGYVLTQQDDL
IAQFEEAASDVVPRLKKLRDFVADNTAQVPFIDQAIASANSRIERFRQVIALAQQGRIEDARQLLRDTDGRRAMDTLTTS
LTAMRQEENRLFSERTTEADRSQALATIITTTGSGLVLVLAGLSIFLVRRSARARDEAENQLRENNLNLESAVQERTADL
REANEEIQRFAYIVSHDLRSPLVNIMGFTSELEELRSDIFRRIGTLSREVTGKQSAANADGDGEAELEPADRQLSEDFTE
ALGFIKSSIGKMDRLISAILNLTREGRRQFQPVRIETRELIENIVSTVAHQAAEANAQIRIEPLPEIVSDRLALEQIFSN
LIDNALKYLKDGVPGDIVIRGRQKLGFVIFEIADNGRGIDPKDHQRIFDLFRRAGTQDRPGQGIGLAHVRALVRRLGGTM
SVSSALGEGSTFTITLPAKWTANKNQEQRA

Sequences:

>Translated_510_residues
MTPESARKRSLAQVTLLSLSFAVLVAISLASVYWLQKAREDNAWVAHTLEVQNQIALAQLQLRRAESAERGYVLTQQDDL
IAQFEEAASDVVPRLKKLRDFVADNTAQVPFIDQAIASANSRIERFRQVIALAQQGRIEDARQLLRDTDGRRAMDTLTTS
LTAMRQEENRLFSERTTEADRSQALATIITTTGSGLVLVLAGLSIFLVRRSARARDEAENQLRENNLNLESAVQERTADL
REANEEIQRFAYIVSHDLRSPLVNIMGFTSELEELRSDIFRRIGTLSREVTGKQSAANADGDGEAELEPADRQLSEDFTE
ALGFIKSSIGKMDRLISAILNLTREGRRQFQPVRIETRELIENIVSTVAHQAAEANAQIRIEPLPEIVSDRLALEQIFSN
LIDNALKYLKDGVPGDIVIRGRQKLGFVIFEIADNGRGIDPKDHQRIFDLFRRAGTQDRPGQGIGLAHVRALVRRLGGTM
SVSSALGEGSTFTITLPAKWTANKNQEQRA
>Mature_509_residues
TPESARKRSLAQVTLLSLSFAVLVAISLASVYWLQKAREDNAWVAHTLEVQNQIALAQLQLRRAESAERGYVLTQQDDLI
AQFEEAASDVVPRLKKLRDFVADNTAQVPFIDQAIASANSRIERFRQVIALAQQGRIEDARQLLRDTDGRRAMDTLTTSL
TAMRQEENRLFSERTTEADRSQALATIITTTGSGLVLVLAGLSIFLVRRSARARDEAENQLRENNLNLESAVQERTADLR
EANEEIQRFAYIVSHDLRSPLVNIMGFTSELEELRSDIFRRIGTLSREVTGKQSAANADGDGEAELEPADRQLSEDFTEA
LGFIKSSIGKMDRLISAILNLTREGRRQFQPVRIETRELIENIVSTVAHQAAEANAQIRIEPLPEIVSDRLALEQIFSNL
IDNALKYLKDGVPGDIVIRGRQKLGFVIFEIADNGRGIDPKDHQRIFDLFRRAGTQDRPGQGIGLAHVRALVRRLGGTMS
VSSALGEGSTFTITLPAKWTANKNQEQRA

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=272, Percent_Identity=27.5735294117647, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790436, Length=318, Percent_Identity=26.4150943396226, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI145693157, Length=390, Percent_Identity=25.1282051282051, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788713, Length=261, Percent_Identity=26.0536398467433, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789149, Length=294, Percent_Identity=26.530612244898, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=28.6290322580645, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56865; Mature: 56734

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPESARKRSLAQVTLLSLSFAVLVAISLASVYWLQKAREDNAWVAHTLEVQNQIALAQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHH
QLRRAESAERGYVLTQQDDLIAQFEEAASDVVPRLKKLRDFVADNTAQVPFIDQAIASAN
HHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
SRIERFRQVIALAQQGRIEDARQLLRDTDGRRAMDTLTTSLTAMRQEENRLFSERTTEAD
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RSQALATIITTTGSGLVLVLAGLSIFLVRRSARARDEAENQLRENNLNLESAVQERTADL
HHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
REANEEIQRFAYIVSHDLRSPLVNIMGFTSELEELRSDIFRRIGTLSREVTGKQSAANAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GDGEAELEPADRQLSEDFTEALGFIKSSIGKMDRLISAILNLTREGRRQFQPVRIETREL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
IENIVSTVAHQAAEANAQIRIEPLPEIVSDRLALEQIFSNLIDNALKYLKDGVPGDIVIR
HHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
GRQKLGFVIFEIADNGRGIDPKDHQRIFDLFRRAGTQDRPGQGIGLAHVRALVRRLGGTM
CCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCH
SVSSALGEGSTFTITLPAKWTANKNQEQRA
HHHHHCCCCCEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
TPESARKRSLAQVTLLSLSFAVLVAISLASVYWLQKAREDNAWVAHTLEVQNQIALAQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHH
QLRRAESAERGYVLTQQDDLIAQFEEAASDVVPRLKKLRDFVADNTAQVPFIDQAIASAN
HHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
SRIERFRQVIALAQQGRIEDARQLLRDTDGRRAMDTLTTSLTAMRQEENRLFSERTTEAD
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RSQALATIITTTGSGLVLVLAGLSIFLVRRSARARDEAENQLRENNLNLESAVQERTADL
HHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
REANEEIQRFAYIVSHDLRSPLVNIMGFTSELEELRSDIFRRIGTLSREVTGKQSAANAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GDGEAELEPADRQLSEDFTEALGFIKSSIGKMDRLISAILNLTREGRRQFQPVRIETREL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
IENIVSTVAHQAAEANAQIRIEPLPEIVSDRLALEQIFSNLIDNALKYLKDGVPGDIVIR
HHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
GRQKLGFVIFEIADNGRGIDPKDHQRIFDLFRRAGTQDRPGQGIGLAHVRALVRRLGGTM
CCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCH
SVSSALGEGSTFTITLPAKWTANKNQEQRA
HHHHHCCCCCEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]