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The map label for this gene is 192290853

Identifier: 192290853

GI number: 192290853

Start: 2664627

End: 2665454

Strand: Reverse

Name: 192290853

Synonym: Rpal_2469

Alternate gene names: NA

Gene position: 2665454-2664627 (Counterclockwise)

Preceding gene: 192290854

Following gene: 192290852

Centisome position: 46.4

GC content: 68.96

Gene sequence:

>828_bases
ATGCGCCTGCGCATCACGCACACCACCAACTATCGATACGAGCCGCCCGCCACCGGCGTGATCCAGGTGCTGCGGATGAC
GCCGAGCAGCCACGACGGGCAGTACGTCGCCGAATGGCAGATCGACATCTCCTCCGACACCCGGCTGGACATGCATTACG
ACGCGTTCGGCAACATCACCCATGTGCTGACGGTCGGTGCCACCGAAGATCTCACCATCACCGCGGACGGGCTGATCGAG
ACCTCCGACACCGGCGGCGTGCTGAAAGGCACCGACGAGCGGTTTCCGCCGCAACTGTTTCTGCGCCCGACCGAGCTGAC
CGACCTCGCGCCGCCGATGCAGGCGCTGGCGCGCGATCTGCGCGGCGACGGCAGCGGCGATACGATCGGCTTCCTGCACG
CGCTGATGACGGCGATCAACAAGCACATCACCTTCGACGACGACCCGACCCATTCCGGCACCACGGCGGCCGAAGCCTTC
GCGCTGCGCCGCGGCGTCTGCCAGGACTACGCGCATGTGTTCATCGCCTGCGCCCGGGCCGGTGGCGTGCCGGCCCGGTT
CGTGTCCGGGCACTTCCTGCGGGCCGACGGCGTGGTGCATCAGCCAGCCGGGCACGCCTGGGCCGAAGCCCATGTGCCGG
GGCTCGGCTGGGTCGGGTTCGATCCGGCCAACGGCATCTGCACCACCGACGCCCACGCCCGGGTCGCGATCGGGCTCGAC
TATCTCGGCGCCGCCCCTGTGCGCGGCACCCGCTACGGCGGCGGACTCGAAACGCTGACCGTGTCGGTGAAGGTCGATCA
GGCCGGCCGGCAGTTTCAGTCGCAATAG

Upstream 100 bases:

>100_bases
GCGGACAACAGTCGGCTCGGCGAAATCGTCGCCAAGCAGTATCTTATCTGATCGAGCACAGGCGCGCCCTGCCCGCCGCC
GCAACCGGACTCTGGACGCC

Downstream 100 bases:

>100_bases
CCTGCGCCCTTCGGGGGCTGGCCGCCGGCGCGGATGGATTAGAGCGTTTTCGAGCGAAGTCGAAACCGGTTCGCGTGAAG
AAAACGCGTCAAGACAAACA

Product: transglutaminase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MRLRITHTTNYRYEPPATGVIQVLRMTPSSHDGQYVAEWQIDISSDTRLDMHYDAFGNITHVLTVGATEDLTITADGLIE
TSDTGGVLKGTDERFPPQLFLRPTELTDLAPPMQALARDLRGDGSGDTIGFLHALMTAINKHITFDDDPTHSGTTAAEAF
ALRRGVCQDYAHVFIACARAGGVPARFVSGHFLRADGVVHQPAGHAWAEAHVPGLGWVGFDPANGICTTDAHARVAIGLD
YLGAAPVRGTRYGGGLETLTVSVKVDQAGRQFQSQ

Sequences:

>Translated_275_residues
MRLRITHTTNYRYEPPATGVIQVLRMTPSSHDGQYVAEWQIDISSDTRLDMHYDAFGNITHVLTVGATEDLTITADGLIE
TSDTGGVLKGTDERFPPQLFLRPTELTDLAPPMQALARDLRGDGSGDTIGFLHALMTAINKHITFDDDPTHSGTTAAEAF
ALRRGVCQDYAHVFIACARAGGVPARFVSGHFLRADGVVHQPAGHAWAEAHVPGLGWVGFDPANGICTTDAHARVAIGLD
YLGAAPVRGTRYGGGLETLTVSVKVDQAGRQFQSQ
>Mature_275_residues
MRLRITHTTNYRYEPPATGVIQVLRMTPSSHDGQYVAEWQIDISSDTRLDMHYDAFGNITHVLTVGATEDLTITADGLIE
TSDTGGVLKGTDERFPPQLFLRPTELTDLAPPMQALARDLRGDGSGDTIGFLHALMTAINKHITFDDDPTHSGTTAAEAF
ALRRGVCQDYAHVFIACARAGGVPARFVSGHFLRADGVVHQPAGHAWAEAHVPGLGWVGFDPANGICTTDAHARVAIGLD
YLGAAPVRGTRYGGGLETLTVSVKVDQAGRQFQSQ

Specific function: Unknown

COG id: COG1305

COG function: function code E; Transglutaminase-like enzymes, putative cysteine proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv2569c [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013589
- InterPro:   IPR002931 [H]

Pfam domain/function: PF08379 Bact_transglu_N; PF01841 Transglut_core [H]

EC number: NA

Molecular weight: Translated: 29561; Mature: 29561

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLRITHTTNYRYEPPATGVIQVLRMTPSSHDGQYVAEWQIDISSDTRLDMHYDAFGNIT
CEEEEEECCCCEECCCCHHHEEEEEECCCCCCCCEEEEEEEEECCCCEEEEEECCCCCEE
HVLTVGATEDLTITADGLIETSDTGGVLKGTDERFPPQLFLRPTELTDLAPPMQALARDL
EEEEECCCCCEEEEECCEEEECCCCCEEECCCCCCCHHEEEECCCCCCCCCHHHHHHHHH
RGDGSGDTIGFLHALMTAINKHITFDDDPTHSGTTAAEAFALRRGVCQDYAHVFIACARA
CCCCCCCHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GGVPARFVSGHFLRADGVVHQPAGHAWAEAHVPGLGWVGFDPANGICTTDAHARVAIGLD
CCCCHHHHCCEEEEECCEEECCCCCCCHHCCCCCCCEECCCCCCCEEECCCCEEEEEEEH
YLGAAPVRGTRYGGGLETLTVSVKVDQAGRQFQSQ
HCCCCCCCCCCCCCCEEEEEEEEEECCCCHHHCCC
>Mature Secondary Structure
MRLRITHTTNYRYEPPATGVIQVLRMTPSSHDGQYVAEWQIDISSDTRLDMHYDAFGNIT
CEEEEEECCCCEECCCCHHHEEEEEECCCCCCCCEEEEEEEEECCCCEEEEEECCCCCEE
HVLTVGATEDLTITADGLIETSDTGGVLKGTDERFPPQLFLRPTELTDLAPPMQALARDL
EEEEECCCCCEEEEECCEEEECCCCCEEECCCCCCCHHEEEECCCCCCCCCHHHHHHHHH
RGDGSGDTIGFLHALMTAINKHITFDDDPTHSGTTAAEAFALRRGVCQDYAHVFIACARA
CCCCCCCHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GGVPARFVSGHFLRADGVVHQPAGHAWAEAHVPGLGWVGFDPANGICTTDAHARVAIGLD
CCCCHHHHCCEEEEECCEEECCCCCCCHHCCCCCCCEECCCCCCCEEECCCCEEEEEEEH
YLGAAPVRGTRYGGGLETLTVSVKVDQAGRQFQSQ
HCCCCCCCCCCCCCCEEEEEEEEEECCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]