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The map label for this gene is 192290749

Identifier: 192290749

GI number: 192290749

Start: 2549818

End: 2551719

Strand: Reverse

Name: 192290749

Synonym: Rpal_2364

Alternate gene names: NA

Gene position: 2551719-2549818 (Counterclockwise)

Preceding gene: 192290750

Following gene: 192290748

Centisome position: 44.42

GC content: 64.09

Gene sequence:

>1902_bases
ATGGATCATTACCTGCGATGGCGGAAGCGGCAGAAGCTGCTCGCCGACTTCGGTGAGTTCGCGCTGAGCAACGACAATCT
GGCCGACATTCTGACGGAAGCCTGTCGCCTCGTCGGCAACGCGCTGGGCACACATCGCGCAAATGTTCTCGAGATCGAAC
CGAGCAACCGAAGCCTGTTCGTGCGCGCGGGAGTCGGCTTGGATGATGGCATCGTCGGCAAGCTCCGGCTGCCGATGCGC
GACATCGCCTCCGAGCGTTTCTCGCCCGATGGCAGCCCCCTCGACATCATTCGCGACGTCCACACCGAGCCCCAATACGA
CCTTGCCGCCTTCATGGAAGCCGCCGGTGTGGTCGCACTCGTCAACGTCCCGATCCTACTGCCGGGCAGAACGCTGTATG
GTTTGCTCCAGGTCGAAAGTTCCGAGCCGCGCGAGTTTTCACAGGACGACGTCGAATTCCTGCGCACCTATTCCACCATC
CTCGGACCGGTGATCGACCGTCTCAACAAAGTACGCGCGCTCCGGGACGCCGAAGAGCGGTTTCGACTGATCGTCGAAGC
CGCGCGCGACTACGCAATCTTCACCACCGATGCCAACGATCGGATCGTCGATTGGCTGCCGGGTGCCGAAGCGGTGTTCG
GATGGACGGCCGCAGAGGCCAAGGGCCGATCGGCCAACATGCTGTTCACGGCCGAGGATCGAGCCTCCGGCGCGGACGTC
AAAGAAATCGAGACAGCGCGCCGCGACGGCTCGGCTCCCAACATCCGCTGGCACGCCCACAAAGGCGGATCGCGGGTCTT
CATCGAAGGCAGTGTCACCAGCGTGCGCGGCAGCGACGGGCAGACTCACGGCTTCCTCAAGATCGGTCAGGATGTCACCG
AGCGGCGCCGAAACGAAGAGCGCATCCGCCAGAGTGAAGCCCGCCAGCGCGCGCTGATCGAAGGCATTCCGCAATTGGTC
TGGCAGGCATCCTCGGATGGAGGCTGGATCTGGTCGAGCCCGCAATGGAGCGACTTCACCGGCCTCGCCCCGATGCGCAG
CCTCGCTTTCGGCTGGCAGGACGCGGTGCATCCCGACGACCGGCGCACAGCATCGACGGCTTGGTCGCGCGCCAATGAGA
CCGGCTCGTTCGAAAGCGAATACCGCATCCGCCACGGTCTCACCGAGACCTATCGCTGGTTCGCGATCCGGGCCGCGCCG
GTGCGTGACAGCGACGGCGAGATCCTGACATGGCTCGGCACCTCCACCGACATCGACGATCTGCGCCGCATGCAGCAGCG
CCAGGAAGTGATGGTGACCGAACTGCAGCATCGCACCCGCAACCTAATTGCCGTAGTGCAATCGATCGCCGAGCAGACGA
TGGCGAGCTGCGGCACGATGGAAGAGTTCCGCCCCCAATTCAACGACCGGCTGACCGCCCTCGCCCGGGTTCAGGGACTG
CTGTCACGTTCAGCGCAAGAACCAATTACCATTGCCACGCTAGTGCGGGCCGCCCTCGATGCCTTGGGCACGGTCGACCG
GAACCGGGTCACGATCAGCGGGCCGAACGTGCCGTTGCGCAATTCCAGCGTTCAGACGCTGGCGCTGGCGCTCCACGAGC
TTGCTACCAATGCCCGCAAATGCGGCGCTCTGTCGATTCTCGTCGGCCGTCTCGAAGTCGCCTGGGAGGTTCGCAAGGCA
CCGGACGGGCGCCATCTCGAACTCGCCTGGATCGAACATGGCCGCAGCTCGGAACAACCCAATACCCCAGGCGCACAGAA
CGGCGGCTACGGACGCACGCTGATCGAACGCGCGCTGCCTTATGCGCTGAGCGCGACCACTACATTCGAGTTGAGGGACG
TCGGCGTACGGTGCACGATCAGGCTTCCCCTCGATACGACCGAAGCGGAGCAGGCGTCATGA

Upstream 100 bases:

>100_bases
CGCGCGCCGCTGAGCGCGGAGTATCGGCAAGCGATGAATCGGCAATAGGAACGTTGTCTCTCCTCCCAGGTTGAACGCGG
TGATTCTCCGGAGTCCCGCA

Downstream 100 bases:

>100_bases
TCAGTCAGTCCACCGCGTTGGCCGGCCTCCGGATTCTTCTGGTCGAGGACGAGTACTTCATCGCCGACGACATGATGCGC
AAGTTCGAGGAGAGCGGTGC

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 633; Mature: 633

Protein sequence:

>633_residues
MDHYLRWRKRQKLLADFGEFALSNDNLADILTEACRLVGNALGTHRANVLEIEPSNRSLFVRAGVGLDDGIVGKLRLPMR
DIASERFSPDGSPLDIIRDVHTEPQYDLAAFMEAAGVVALVNVPILLPGRTLYGLLQVESSEPREFSQDDVEFLRTYSTI
LGPVIDRLNKVRALRDAEERFRLIVEAARDYAIFTTDANDRIVDWLPGAEAVFGWTAAEAKGRSANMLFTAEDRASGADV
KEIETARRDGSAPNIRWHAHKGGSRVFIEGSVTSVRGSDGQTHGFLKIGQDVTERRRNEERIRQSEARQRALIEGIPQLV
WQASSDGGWIWSSPQWSDFTGLAPMRSLAFGWQDAVHPDDRRTASTAWSRANETGSFESEYRIRHGLTETYRWFAIRAAP
VRDSDGEILTWLGTSTDIDDLRRMQQRQEVMVTELQHRTRNLIAVVQSIAEQTMASCGTMEEFRPQFNDRLTALARVQGL
LSRSAQEPITIATLVRAALDALGTVDRNRVTISGPNVPLRNSSVQTLALALHELATNARKCGALSILVGRLEVAWEVRKA
PDGRHLELAWIEHGRSSEQPNTPGAQNGGYGRTLIERALPYALSATTTFELRDVGVRCTIRLPLDTTEAEQAS

Sequences:

>Translated_633_residues
MDHYLRWRKRQKLLADFGEFALSNDNLADILTEACRLVGNALGTHRANVLEIEPSNRSLFVRAGVGLDDGIVGKLRLPMR
DIASERFSPDGSPLDIIRDVHTEPQYDLAAFMEAAGVVALVNVPILLPGRTLYGLLQVESSEPREFSQDDVEFLRTYSTI
LGPVIDRLNKVRALRDAEERFRLIVEAARDYAIFTTDANDRIVDWLPGAEAVFGWTAAEAKGRSANMLFTAEDRASGADV
KEIETARRDGSAPNIRWHAHKGGSRVFIEGSVTSVRGSDGQTHGFLKIGQDVTERRRNEERIRQSEARQRALIEGIPQLV
WQASSDGGWIWSSPQWSDFTGLAPMRSLAFGWQDAVHPDDRRTASTAWSRANETGSFESEYRIRHGLTETYRWFAIRAAP
VRDSDGEILTWLGTSTDIDDLRRMQQRQEVMVTELQHRTRNLIAVVQSIAEQTMASCGTMEEFRPQFNDRLTALARVQGL
LSRSAQEPITIATLVRAALDALGTVDRNRVTISGPNVPLRNSSVQTLALALHELATNARKCGALSILVGRLEVAWEVRKA
PDGRHLELAWIEHGRSSEQPNTPGAQNGGYGRTLIERALPYALSATTTFELRDVGVRCTIRLPLDTTEAEQAS
>Mature_633_residues
MDHYLRWRKRQKLLADFGEFALSNDNLADILTEACRLVGNALGTHRANVLEIEPSNRSLFVRAGVGLDDGIVGKLRLPMR
DIASERFSPDGSPLDIIRDVHTEPQYDLAAFMEAAGVVALVNVPILLPGRTLYGLLQVESSEPREFSQDDVEFLRTYSTI
LGPVIDRLNKVRALRDAEERFRLIVEAARDYAIFTTDANDRIVDWLPGAEAVFGWTAAEAKGRSANMLFTAEDRASGADV
KEIETARRDGSAPNIRWHAHKGGSRVFIEGSVTSVRGSDGQTHGFLKIGQDVTERRRNEERIRQSEARQRALIEGIPQLV
WQASSDGGWIWSSPQWSDFTGLAPMRSLAFGWQDAVHPDDRRTASTAWSRANETGSFESEYRIRHGLTETYRWFAIRAAP
VRDSDGEILTWLGTSTDIDDLRRMQQRQEVMVTELQHRTRNLIAVVQSIAEQTMASCGTMEEFRPQFNDRLTALARVQGL
LSRSAQEPITIATLVRAALDALGTVDRNRVTISGPNVPLRNSSVQTLALALHELATNARKCGALSILVGRLEVAWEVRKA
PDGRHLELAWIEHGRSSEQPNTPGAQNGGYGRTLIERALPYALSATTTFELRDVGVRCTIRLPLDTTEAEQAS

Specific function: Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light. Once ejected from an infected animal host, sunlight acts as an environmental signal that increases the virulence of the bacterium, preparing it for infection o

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR011102 [H]

Pfam domain/function: PF07536 HWE_HK; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70485; Mature: 70485

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50112 PAS ; PS50113 PAC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHYLRWRKRQKLLADFGEFALSNDNLADILTEACRLVGNALGTHRANVLEIEPSNRSLF
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEE
VRAGVGLDDGIVGKLRLPMRDIASERFSPDGSPLDIIRDVHTEPQYDLAAFMEAAGVVAL
EEECCCCCCCCEEEEECCHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCEEEE
VNVPILLPGRTLYGLLQVESSEPREFSQDDVEFLRTYSTILGPVIDRLNKVRALRDAEER
EECCEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRLIVEAARDYAIFTTDANDRIVDWLPGAEAVFGWTAAEAKGRSANMLFTAEDRASGADV
HHHHHHHHCCEEEEEECCCCCEEEECCCCCHHEEEEHHCCCCCCCCEEEEECCCCCCCCH
KEIETARRDGSAPNIRWHAHKGGSRVFIEGSVTSVRGSDGQTHGFLKIGQDVTERRRNEE
HHHHHHHHCCCCCCEEEEEECCCCEEEEECCEEEECCCCCCCCCCEEECHHHHHHHHHHH
RIRQSEARQRALIEGIPQLVWQASSDGGWIWSSPQWSDFTGLAPMRSLAFGWQDAVHPDD
HHHHHHHHHHHHHHHHHHHHEECCCCCCEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCC
RRTASTAWSRANETGSFESEYRIRHGLTETYRWFAIRAAPVRDSDGEILTWLGTSTDIDD
CHHHHHHHHHCCCCCCCCHHHHHHHCHHHHEEEEEEEECCCCCCCCCEEEEECCCCCHHH
LRRMQQRQEVMVTELQHRTRNLIAVVQSIAEQTMASCGTMEEFRPQFNDRLTALARVQGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LSRSAQEPITIATLVRAALDALGTVDRNRVTISGPNVPLRNSSVQTLALALHELATNARK
HHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
CGALSILVGRLEVAWEVRKAPDGRHLELAWIEHGRSSEQPNTPGAQNGGYGRTLIERALP
CCHHHHHHHHHHHEEEHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCC
YALSATTTFELRDVGVRCTIRLPLDTTEAEQAS
CEEECCEEEEEEECCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MDHYLRWRKRQKLLADFGEFALSNDNLADILTEACRLVGNALGTHRANVLEIEPSNRSLF
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEE
VRAGVGLDDGIVGKLRLPMRDIASERFSPDGSPLDIIRDVHTEPQYDLAAFMEAAGVVAL
EEECCCCCCCCEEEEECCHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCEEEE
VNVPILLPGRTLYGLLQVESSEPREFSQDDVEFLRTYSTILGPVIDRLNKVRALRDAEER
EECCEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRLIVEAARDYAIFTTDANDRIVDWLPGAEAVFGWTAAEAKGRSANMLFTAEDRASGADV
HHHHHHHHCCEEEEEECCCCCEEEECCCCCHHEEEEHHCCCCCCCCEEEEECCCCCCCCH
KEIETARRDGSAPNIRWHAHKGGSRVFIEGSVTSVRGSDGQTHGFLKIGQDVTERRRNEE
HHHHHHHHCCCCCCEEEEEECCCCEEEEECCEEEECCCCCCCCCCEEECHHHHHHHHHHH
RIRQSEARQRALIEGIPQLVWQASSDGGWIWSSPQWSDFTGLAPMRSLAFGWQDAVHPDD
HHHHHHHHHHHHHHHHHHHHEECCCCCCEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCC
RRTASTAWSRANETGSFESEYRIRHGLTETYRWFAIRAAPVRDSDGEILTWLGTSTDIDD
CHHHHHHHHHCCCCCCCCHHHHHHHCHHHHEEEEEEEECCCCCCCCCEEEEECCCCCHHH
LRRMQQRQEVMVTELQHRTRNLIAVVQSIAEQTMASCGTMEEFRPQFNDRLTALARVQGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LSRSAQEPITIATLVRAALDALGTVDRNRVTISGPNVPLRNSSVQTLALALHELATNARK
HHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
CGALSILVGRLEVAWEVRKAPDGRHLELAWIEHGRSSEQPNTPGAQNGGYGRTLIERALP
CCHHHHHHHHHHHEEEHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCC
YALSATTTFELRDVGVRCTIRLPLDTTEAEQAS
CEEECCEEEEEEECCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA