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The map label for this gene is ycgM [C]

Identifier: 192290543

GI number: 192290543

Start: 2330489

End: 2331274

Strand: Reverse

Name: ycgM [C]

Synonym: Rpal_2152

Alternate gene names: 192290543

Gene position: 2331274-2330489 (Counterclockwise)

Preceding gene: 192290544

Following gene: 192290542

Centisome position: 40.59

GC content: 63.74

Gene sequence:

>786_bases
ATGACCAAATGGGTTCGTTTTCGCGCAGGTGGCGCGGTCGGGTTCGGGACCATCGCGCATTCCGATATCACCGTGCATGA
CGGCGACATGTTCGGCGCAAGCAAGCCGACCGGGCAGACGCTGCAGCTCGGTGATGTCGAGCTGCTCAGCCCGTGCACGC
CGGGCAAGATCATCGGGCTGTGGAACAACTTTCGCGCGCTCGCCGCCAAGCTCAATCAGTCGATCCCGCCGGAGCCATTG
TACTTCCTGAAAGCCACCACCAGCGTCACGTCGCACGGCGCCGTGGTGAGCCGTCCCGCCTCCTACGACGGCAAGGTAGT
TTACGAAGGCGAACTCGGCATCGTCATCGGCAGGCGTTGCAGCAACGTCTCGGAAGCCGAGGCCGCATCGCATATCTTCG
GCTACACCTGCGTCAACGACATCACCGCCGCCGATATCCTCAATCGCGATCCGAGCTTCCCGCAATGGGCGCGGGCCAAG
AGCTTCGACGGCTTCGGCCCATTCGGCCCGGCGATCGCCACCGGGCTCGATCCGCAGGCGCTGTCGATCCGCACCATTCT
GAACGGCGCCGAGCGACAGAACTACCCGGTTGCCGACATGATCTTCGCGCCACATCAGCTCGTCAGCCTGCTGTCGCACG
ACATGACGCTGGAGCCCGGCGATTTGATCTGCTGCGGCACCTCGGTCGGCGTCGGCGTGATGAAGGAGCCGGTCAACGCC
GTCACCATCGCGATCGAAGGCATCGGCGAACTGCACAACGAATTCCGCCAGACGGCGAAAGCCTGA

Upstream 100 bases:

>100_bases
GGAATCCCGAGGTTGTTAGCACGCCTAGTCCATTGAGATTCCGGGTTCGCGCATTTCATGCGCGCCCCGGAATGACTCCC
GAGTTGAGGAACACTACGCC

Downstream 100 bases:

>100_bases
CGATCCTTCCACGTGCCGTCATTCCGGGGCGCGCGCAGCGCGAACCCGGAATCCCGAAGTTGTTTTCATCTCGCAGAGAT
TCCGGGTTCGCTCGCTGACG

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTKWVRFRAGGAVGFGTIAHSDITVHDGDMFGASKPTGQTLQLGDVELLSPCTPGKIIGLWNNFRALAAKLNQSIPPEPL
YFLKATTSVTSHGAVVSRPASYDGKVVYEGELGIVIGRRCSNVSEAEAASHIFGYTCVNDITAADILNRDPSFPQWARAK
SFDGFGPFGPAIATGLDPQALSIRTILNGAERQNYPVADMIFAPHQLVSLLSHDMTLEPGDLICCGTSVGVGVMKEPVNA
VTIAIEGIGELHNEFRQTAKA

Sequences:

>Translated_261_residues
MTKWVRFRAGGAVGFGTIAHSDITVHDGDMFGASKPTGQTLQLGDVELLSPCTPGKIIGLWNNFRALAAKLNQSIPPEPL
YFLKATTSVTSHGAVVSRPASYDGKVVYEGELGIVIGRRCSNVSEAEAASHIFGYTCVNDITAADILNRDPSFPQWARAK
SFDGFGPFGPAIATGLDPQALSIRTILNGAERQNYPVADMIFAPHQLVSLLSHDMTLEPGDLICCGTSVGVGVMKEPVNA
VTIAIEGIGELHNEFRQTAKA
>Mature_260_residues
TKWVRFRAGGAVGFGTIAHSDITVHDGDMFGASKPTGQTLQLGDVELLSPCTPGKIIGLWNNFRALAAKLNQSIPPEPLY
FLKATTSVTSHGAVVSRPASYDGKVVYEGELGIVIGRRCSNVSEAEAASHIFGYTCVNDITAADILNRDPSFPQWARAKS
FDGFGPFGPAIATGLDPQALSIRTILNGAERQNYPVADMIFAPHQLVSLLSHDMTLEPGDLICCGTSVGVGVMKEPVNAV
TIAIEGIGELHNEFRQTAKA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI40786394, Length=225, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI156231349, Length=226, Percent_Identity=32.7433628318584, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI13654274, Length=211, Percent_Identity=31.2796208530806, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI215422413, Length=211, Percent_Identity=31.2796208530806, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI66348062, Length=211, Percent_Identity=31.2796208530806, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1787428, Length=196, Percent_Identity=29.0816326530612, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17557057, Length=179, Percent_Identity=31.2849162011173, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324161, Length=216, Percent_Identity=28.2407407407407, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28572127, Length=222, Percent_Identity=35.5855855855856, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24663695, Length=221, Percent_Identity=35.7466063348416, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28571789, Length=185, Percent_Identity=39.4594594594595, Blast_Score=107, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 27770; Mature: 27639

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKWVRFRAGGAVGFGTIAHSDITVHDGDMFGASKPTGQTLQLGDVELLSPCTPGKIIGL
CCCEEEEECCCCEEECEEECCCEEEECCCCCCCCCCCCCEEEECCEEEECCCCCCEEEEE
WNNFRALAAKLNQSIPPEPLYFLKATTSVTSHGAVVSRPASYDGKVVYEGELGIVIGRRC
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEECCCCCCCEEEEECCEEEEECCCC
SNVSEAEAASHIFGYTCVNDITAADILNRDPSFPQWARAKSFDGFGPFGPAIATGLDPQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCHHHHCCCCCHH
LSIRTILNGAERQNYPVADMIFAPHQLVSLLSHDMTLEPGDLICCGTSVGVGVMKEPVNA
HHHHHHHCCHHCCCCCHHHHHHCHHHHHHHHHCCCEECCCCEEEECCCCCCCHHHCCCCE
VTIAIEGIGELHNEFRQTAKA
EEEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKWVRFRAGGAVGFGTIAHSDITVHDGDMFGASKPTGQTLQLGDVELLSPCTPGKIIGL
CCEEEEECCCCEEECEEECCCEEEECCCCCCCCCCCCCEEEECCEEEECCCCCCEEEEE
WNNFRALAAKLNQSIPPEPLYFLKATTSVTSHGAVVSRPASYDGKVVYEGELGIVIGRRC
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEECCCCCCCEEEEECCEEEEECCCC
SNVSEAEAASHIFGYTCVNDITAADILNRDPSFPQWARAKSFDGFGPFGPAIATGLDPQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCHHHHCCCCCHH
LSIRTILNGAERQNYPVADMIFAPHQLVSLLSHDMTLEPGDLICCGTSVGVGVMKEPVNA
HHHHHHHCCHHCCCCCHHHHHHCHHHHHHHHHCCCEECCCCEEEECCCCCCCHHHCCCCE
VTIAIEGIGELHNEFRQTAKA
EEEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]