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The map label for this gene is flhA [H]

Identifier: 192290224

GI number: 192290224

Start: 1962330

End: 1964462

Strand: Reverse

Name: flhA [H]

Synonym: Rpal_1828

Alternate gene names: 192290224

Gene position: 1964462-1962330 (Counterclockwise)

Preceding gene: 192290226

Following gene: 192290223

Centisome position: 34.2

GC content: 66.39

Gene sequence:

>2133_bases
ATGACGGACACCACGGTCGGCCAGAGCACTGGGTCCGGCATTCCCAGCCTCAACGAAATGATCGCCATACTGCGGCGCGG
CGACCTCGCGCTCGCGATCGGCGTGCTGACTATCCTGGTCGTGCTGATCCTGCCGCTGCCGGCGATCATTCTCGACCTGT
TCCTGGCGATCTCGATCACGCTGTCGATCCTGATCCTGATGACGTCGCTGTTCATCCAGGCGCCGCTGGAATTCTCGTCG
TTCCCGACCGTGCTCCTGATCTCGACGATGTTGCGGCTGTCGCTGAACATGGCGTCGACCCGGCTGATCCTGTCGCACGG
CCATGAAGGCACCGCGGCCGCCGGTCACGTCATCGAGGCGTTCGGCGGCTTCGTGATGGGCGGCAATTTCGTCATCGGGA
TCATCGTGTTCACGATCCTGATCATCGTCAACTTCGTGGTCATCACCAAGGGTTCGGGCCGCATCGCCGAAGTCGCGGCG
CGTTTCCAATTGGACTCGATGCCCGGCAAGCAGATGGCGATCGACGCCGACCTGTCGGCCGGCCTGATCGACGAAGCCAC
CGCCAAAGCGCGGCGCAAGGAGCTCGAAGACGAAAGCGGCTTCTTCGGCGCCATGGACGGTGCGTCGAAGTTCGTCCGCG
GCGACGCCATCGCCGGCCTCTTGATCGTGTTTATCAACGTGATCGGCGGCATCATCATCGGCGTCGCGCAGCAGGGCCTG
TCTTTCTCGGAAGCCGGGCACACCTATACGCTGCTCACCGTCGGCGACGGCCTGGTCACTCAGATCCCGGCGCTGATCGT
GTCGACCGCGGCGGGCCTGCTGGTCTCGAAGGCCGGCATCTCCGGCTCGGCCGACAAGGCGATGATGGGCCAGCTCTCCG
GCTACCCGCAGGCGCTCGGCATGGCGGCCGCGGTGATGCTGGTGCTGGCGGTGCTGCCGGGCATTCCGACCCTGCCGTTC
CTGGCGCTCGGCAGCGGCTCGGCCTACCTGGCCTTGAAGGCGCGCAACCGCAAACGGGAGGTCACTGCCGAGGCGGCGCA
GGCCGCAGCCGCGCCGGAAGCAGCCGCTGCCGCTGCGGCGGCCGCTTCCGCGGCGGAGGAGCCGATCGCCGCAGCGCTGA
AGATCGATGATCTGAAGATCGAGCTCGGCTACGCGCTCTTGCCGCTGGTCAACGGCCCCGACGGCCAGGACCGCCTGACC
GAGCAGATCAAGGCGCTGCGCCGGTCGCTGGCGATCGAGATGGGCTTCGTGATGCCGGCTGTGCGCATCCTCGACAACGT
CCAGCTCGAGGCCAACACCTACGTCATCAAGATCAAGGAAGTCGACGCCGGCACCGGCCGGATCTGGCCGAACCAGTTCA
TGGTCATGGACCCGGCCGGCGAACAGGTGACGGTGCCCGGCATTCACACCACCGAGCCGACCTTCGGCCTGCCCGCGACC
TGGGTCGACGCCAACTTCAAGGAAGAGGCGTCGCTGAAGGGCTACACCGTGGTCGACGCCGCCACCGTGCTGTCGACGCA
TCTGACCGAGCTGCTCAAGGCCAACATGTCCGACCTGTTGTCCTATGGCGAAACCCAGAAGCTGCTCAAAGACCTGCCGA
AGGAACAGGGCGAGCTGGTCAAGGATATCGTCCCGGGTCAGATCACCGTCTCGGGCATCCAGCGCGTGCTCCAGCTGCTG
CTCGCCGAGCGCGTCTCGATCCGCGACCTGTCGACCATCCTCGAAGGCATCGCCGAAGCGCTGGCGTTCTCGCGCAATCC
GTCGACGATCGTCGAGCACGTCCGCGCCCGGCTGGCGCGCCAGATCTGCGCGCAGAACACCTCCTACAACGGCTACCTGC
CGCTGATCGCGCTGTCGGCGAAGTGGGAGCAGGCGTTCGCCGAATCGATCATCGGCCAGGGCGAAGACCGCACCCTGGCG
ATGGCGCCGTCGAAGCTGTCGGAATTCATGACCGCGGTGCGCGACAAGTTCGAGCAGGCCGCGCGCGAAGGCGAGGCCCC
GGTGCTGGTGACATCCGCCTCGATCCGGCCGTTCGTCCGCTCGCTGGTCGAGCGCTTCCGCGCCCAGACCACCGTGATGT
CGCAGGCCGAGATCCATCCGCGGGCGCGGCTGAAAACGGTCGGCAGCGTCTGA

Upstream 100 bases:

>100_bases
GGACGCCAGTGCGCTGCCTCACGTTGGACCCAGCGCCCCTCCGGTCGCGGCGAAGACGTCTGGCCGGCGCAAGCGACGCG
CACAGGGGACGGCGGCTGAA

Downstream 100 bases:

>100_bases
GCCCGGGAGTTCCCGCAGCGCCTGCTTCGTTTCGGCTGCGCGACTTTTGCGCAACAGACAAGCCCTACCACCCAGAATGG
CGTTGGGGCGGTGATAAGCG

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 710; Mature: 709

Protein sequence:

>710_residues
MTDTTVGQSTGSGIPSLNEMIAILRRGDLALAIGVLTILVVLILPLPAIILDLFLAISITLSILILMTSLFIQAPLEFSS
FPTVLLISTMLRLSLNMASTRLILSHGHEGTAAAGHVIEAFGGFVMGGNFVIGIIVFTILIIVNFVVITKGSGRIAEVAA
RFQLDSMPGKQMAIDADLSAGLIDEATAKARRKELEDESGFFGAMDGASKFVRGDAIAGLLIVFINVIGGIIIGVAQQGL
SFSEAGHTYTLLTVGDGLVTQIPALIVSTAAGLLVSKAGISGSADKAMMGQLSGYPQALGMAAAVMLVLAVLPGIPTLPF
LALGSGSAYLALKARNRKREVTAEAAQAAAAPEAAAAAAAAASAAEEPIAAALKIDDLKIELGYALLPLVNGPDGQDRLT
EQIKALRRSLAIEMGFVMPAVRILDNVQLEANTYVIKIKEVDAGTGRIWPNQFMVMDPAGEQVTVPGIHTTEPTFGLPAT
WVDANFKEEASLKGYTVVDAATVLSTHLTELLKANMSDLLSYGETQKLLKDLPKEQGELVKDIVPGQITVSGIQRVLQLL
LAERVSIRDLSTILEGIAEALAFSRNPSTIVEHVRARLARQICAQNTSYNGYLPLIALSAKWEQAFAESIIGQGEDRTLA
MAPSKLSEFMTAVRDKFEQAAREGEAPVLVTSASIRPFVRSLVERFRAQTTVMSQAEIHPRARLKTVGSV

Sequences:

>Translated_710_residues
MTDTTVGQSTGSGIPSLNEMIAILRRGDLALAIGVLTILVVLILPLPAIILDLFLAISITLSILILMTSLFIQAPLEFSS
FPTVLLISTMLRLSLNMASTRLILSHGHEGTAAAGHVIEAFGGFVMGGNFVIGIIVFTILIIVNFVVITKGSGRIAEVAA
RFQLDSMPGKQMAIDADLSAGLIDEATAKARRKELEDESGFFGAMDGASKFVRGDAIAGLLIVFINVIGGIIIGVAQQGL
SFSEAGHTYTLLTVGDGLVTQIPALIVSTAAGLLVSKAGISGSADKAMMGQLSGYPQALGMAAAVMLVLAVLPGIPTLPF
LALGSGSAYLALKARNRKREVTAEAAQAAAAPEAAAAAAAAASAAEEPIAAALKIDDLKIELGYALLPLVNGPDGQDRLT
EQIKALRRSLAIEMGFVMPAVRILDNVQLEANTYVIKIKEVDAGTGRIWPNQFMVMDPAGEQVTVPGIHTTEPTFGLPAT
WVDANFKEEASLKGYTVVDAATVLSTHLTELLKANMSDLLSYGETQKLLKDLPKEQGELVKDIVPGQITVSGIQRVLQLL
LAERVSIRDLSTILEGIAEALAFSRNPSTIVEHVRARLARQICAQNTSYNGYLPLIALSAKWEQAFAESIIGQGEDRTLA
MAPSKLSEFMTAVRDKFEQAAREGEAPVLVTSASIRPFVRSLVERFRAQTTVMSQAEIHPRARLKTVGSV
>Mature_709_residues
TDTTVGQSTGSGIPSLNEMIAILRRGDLALAIGVLTILVVLILPLPAIILDLFLAISITLSILILMTSLFIQAPLEFSSF
PTVLLISTMLRLSLNMASTRLILSHGHEGTAAAGHVIEAFGGFVMGGNFVIGIIVFTILIIVNFVVITKGSGRIAEVAAR
FQLDSMPGKQMAIDADLSAGLIDEATAKARRKELEDESGFFGAMDGASKFVRGDAIAGLLIVFINVIGGIIIGVAQQGLS
FSEAGHTYTLLTVGDGLVTQIPALIVSTAAGLLVSKAGISGSADKAMMGQLSGYPQALGMAAAVMLVLAVLPGIPTLPFL
ALGSGSAYLALKARNRKREVTAEAAQAAAAPEAAAAAAAAASAAEEPIAAALKIDDLKIELGYALLPLVNGPDGQDRLTE
QIKALRRSLAIEMGFVMPAVRILDNVQLEANTYVIKIKEVDAGTGRIWPNQFMVMDPAGEQVTVPGIHTTEPTFGLPATW
VDANFKEEASLKGYTVVDAATVLSTHLTELLKANMSDLLSYGETQKLLKDLPKEQGELVKDIVPGQITVSGIQRVLQLLL
AERVSIRDLSTILEGIAEALAFSRNPSTIVEHVRARLARQICAQNTSYNGYLPLIALSAKWEQAFAESIIGQGEDRTLAM
APSKLSEFMTAVRDKFEQAAREGEAPVLVTSASIRPFVRSLVERFRAQTTVMSQAEIHPRARLKTVGSV

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=683, Percent_Identity=42.606149341142, Blast_Score=523, Evalue=1e-149,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75138; Mature: 75006

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTTVGQSTGSGIPSLNEMIAILRRGDLALAIGVLTILVVLILPLPAIILDLFLAISIT
CCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSILILMTSLFIQAPLEFSSFPTVLLISTMLRLSLNMASTRLILSHGHEGTAAAGHVIEA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHH
FGGFVMGGNFVIGIIVFTILIIVNFVVITKGSGRIAEVAARFQLDSMPGKQMAIDADLSA
HCCEEECCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCCCCEEEECCCCC
GLIDEATAKARRKELEDESGFFGAMDGASKFVRGDAIAGLLIVFINVIGGIIIGVAQQGL
CHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SFSEAGHTYTLLTVGDGLVTQIPALIVSTAAGLLVSKAGISGSADKAMMGQLSGYPQALG
CHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHH
MAAAVMLVLAVLPGIPTLPFLALGSGSAYLALKARNRKREVTAEAAQAAAAPEAAAAAAA
HHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHH
AASAAEEPIAAALKIDDLKIELGYALLPLVNGPDGQDRLTEQIKALRRSLAIEMGFVMPA
HHHHHCCCHHHHEEEECEEEEECCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VRILDNVQLEANTYVIKIKEVDAGTGRIWPNQFMVMDPAGEQVTVPGIHTTEPTFGLPAT
HHHHHCCEEECCEEEEEEEEECCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCC
WVDANFKEEASLKGYTVVDAATVLSTHLTELLKANMSDLLSYGETQKLLKDLPKEQGELV
EECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHCCHHHHHHH
KDIVPGQITVSGIQRVLQLLLAERVSIRDLSTILEGIAEALAFSRNPSTIVEHVRARLAR
HHHCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QICAQNTSYNGYLPLIALSAKWEQAFAESIIGQGEDRTLAMAPSKLSEFMTAVRDKFEQA
HHHHCCCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHH
AREGEAPVLVTSASIRPFVRSLVERFRAQTTVMSQAEIHPRARLKTVGSV
HHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCC
>Mature Secondary Structure 
TDTTVGQSTGSGIPSLNEMIAILRRGDLALAIGVLTILVVLILPLPAIILDLFLAISIT
CCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSILILMTSLFIQAPLEFSSFPTVLLISTMLRLSLNMASTRLILSHGHEGTAAAGHVIEA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHH
FGGFVMGGNFVIGIIVFTILIIVNFVVITKGSGRIAEVAARFQLDSMPGKQMAIDADLSA
HCCEEECCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCCCCEEEECCCCC
GLIDEATAKARRKELEDESGFFGAMDGASKFVRGDAIAGLLIVFINVIGGIIIGVAQQGL
CHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SFSEAGHTYTLLTVGDGLVTQIPALIVSTAAGLLVSKAGISGSADKAMMGQLSGYPQALG
CHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHH
MAAAVMLVLAVLPGIPTLPFLALGSGSAYLALKARNRKREVTAEAAQAAAAPEAAAAAAA
HHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHH
AASAAEEPIAAALKIDDLKIELGYALLPLVNGPDGQDRLTEQIKALRRSLAIEMGFVMPA
HHHHHCCCHHHHEEEECEEEEECCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VRILDNVQLEANTYVIKIKEVDAGTGRIWPNQFMVMDPAGEQVTVPGIHTTEPTFGLPAT
HHHHHCCEEECCEEEEEEEEECCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCC
WVDANFKEEASLKGYTVVDAATVLSTHLTELLKANMSDLLSYGETQKLLKDLPKEQGELV
EECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHCCHHHHHHH
KDIVPGQITVSGIQRVLQLLLAERVSIRDLSTILEGIAEALAFSRNPSTIVEHVRARLAR
HHHCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QICAQNTSYNGYLPLIALSAKWEQAFAESIIGQGEDRTLAMAPSKLSEFMTAVRDKFEQA
HHHHCCCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHH
AREGEAPVLVTSASIRPFVRSLVERFRAQTTVMSQAEIHPRARLKTVGSV
HHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1938923; 1732219; 11259647 [H]