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The map label for this gene is putA [H]

Identifier: 192290166

GI number: 192290166

Start: 1899728

End: 1902736

Strand: Reverse

Name: putA [H]

Synonym: Rpal_1768

Alternate gene names: 192290166

Gene position: 1902736-1899728 (Counterclockwise)

Preceding gene: 192290168

Following gene: 192290165

Centisome position: 33.13

GC content: 67.73

Gene sequence:

>3009_bases
ATGCCGTCAGACCCGCCGCTTGCCGAATTCACCGCGGCTTACGCGCCGGACGATGCTGCGCTGGCTGCGGAGCTGCTGAC
GACCGCCACGCTGACGCCCGACCGTGAAGCCCAGATCGACGCCATCGCGACCGACCTGATCACCGCGATCCGCGGTTCCG
AACACGGCCTGAGGGGCGTCGAAGCCATGCTGCGCGAATTCGCGCTGTCGACCAAAGAAGGCCTGGCCCTGATGGTGCTG
GCCGAGGCGCTGCTGCGGGTACCGGATGCTGCGACTGCGGACGCCTTCATCGAGGACAAGCTCGGCCAGGGCGACTTCGC
GCATCACCGTATCAAGTCCGATGCCGTGCTGGTGAACGCCTCTGCCTGGGCCCTCGGACTATCGGCACGCCTCGTCCATG
CCGGCGAGACGCCGCAAGGCACGCTTGCGGCCTTAACGCGGCGGATCGGCGCGCCCGCGGTGCGCGCCGCGACACGTCAG
GCGATGCGGCTGATCGGCAATCACTTCGTGCTCGGCGAAACGATCGACGCGGCGCTCGCCCGCGCACAGCCGTATGCGCG
TGAGGGCTCTCGCTATTCTTACGACATGCTCGGCGAAGGCGCCCGCACTGCCGCGGATGCCGAACGTTATTACCAATCCT
ACGCCGATGCGATCATCGCGATCGGCCGCCGCGCCGGCAACGCGGCGCTGCCGGCGAGGCCTGGCATCTCGGTGAAGCTG
TCGGCGCTGCATCCACGGTTCGAGGCGATCAGCCGCGACCGCGTGATGCGGGAACTGACGCCGCGGCTGCTCAAACTGGC
GCAGCTCGCCAAGAGCCACGACCTCGCCTTCACGGTCGATGCCGAAGAAGCCGACCGGCTCGAGCTGTCGCTCGAGGTGT
TCGCCGCCTGCTTTGCCGATCCATCGCTCAAAGGCTGGGACGGTTACGGTCTCGCGGTGCAGGCGTATCAGAAGCGTGCC
GCCACGGTGATCGACCACGTCGCCGAGCTCGCCCGCGCGTTCGACCGCCGCATGATGCTGCGGCTGGTGAAGGGCGCCTA
TTGGGACACCGAGATCAAGCGCACTCAGGAGCGCGGGCTTGCCGACTATCCGGTGTTCACCAGGAAGCCGATGACCGATC
TCAACTACCTGCACTGCGCCCGCAAGCTGCTGGCGCTGCGCCCGCACCTGTTCCCGCAATTCGCCAGTCACAATGCGCTG
ACGGTCGCCACCATCCTGGCCGAGGCTGGTGATTGCGACGGCTACGAATTCCAGCGGCTGCACGGCATGGGCGAGGCACT
GTATGCCCGGCTGCTCGCCGACCACCCGCAGGCGATGTGCCGGATCTACGCGCCGGTCGGCGGGCATAGCGACCTGCTGG
CATATCTGGTGCGGCGCCTCTTGGAGAACGGCGCCAATTCATCGTTCGTGGCCCAAGCCGGCGACGACAGCGTGCCGATC
GCCGAACTACTGACGCGACCTGCAACACTGATCGGCCATCCCGAGAACGCGCGCAACTCGGCCATCCCATTGCCGCGTGA
TCTGTACCAGCCGCAGCGGATCAATTCGCGTGGCATCGAATTCGGCGACCGCAGCGCGCTCGCGGCACTGCTCGGCGACA
TCGAAAGCGCACGCCGGCCGCTGCCGACGGTCGCGTCCACCACGCCGGAACAAGCCGCTGCCACGGTCACTGCCGCACGC
AAAGGCTTCGAGTCCTGGAGCCGGACGTCCGCCGATCATCGCGCCGCGATCCTGCAGCGCGCCGGCGATCTGCTGGAGCA
ACGCCGTGGCGAGCTGATCGCGCTCCTGCAGGACGAAGGCGGCAAGACGCTCGATGATGGCGTGGCGGAAGTGCGCGAAG
CAGTCGACTACTGCCGCTACTACGCCAGCGAGGGTCGCCGGCTGTTCGGCGGGCCGCTGGTCCTCCCTGGCCCGACCGGC
GAGCGCAACACGCTGACCTTGCGTGGCCGCGGCGTGTTCGTCGCGATCAGCCCCTGGAACTTTCCGTTGGCGATCTTCCT
CGGCCAGATCACGGCGGCGCTGATGGCCGGCAACGCGGTGGTCGCAAAGCCGGCCGAGCAGACGCCGGTGATTGCCGAGG
TCGCGGTGCGCCTGTTGCACGCAGCCGGCGTGCCGCCGGCTGCGCTGCATCTGGTGCAAGGCGACGGCCGCATCGGCGCG
GCACTGATCGAGCAGCGCGACATCGCCGGCGTCGTATTCACGGGATCGACCGAGGTCGCGCGTGCGATCAACCGGACACT
GGCCGCCAAGGACGGTCCGATCGTGCCGCTGATCGCCGAGACCGGCGGCATCAACGCGATGATCGTCGATGCCACCGCGC
TGCCCGAGCAGGTCGCCGACGACGTCATTGCCTCTGCATTCCGCTCCGCTGGTCAGCGCTGTTCGGCGCTGCGGCTCCTG
TGCGTGCAGGACGACGTTGCCGACCGAGTGATCGCGATGATCGCCGGCGCGGCGCGCGAGCTAACAATAGGCGATCCGCG
CGATCCGGCGACGCATGTCGGACCGGTGATCGACGCCGAGGCGAAGACCAGGCTCGAAACGCATATCGCCGCGATGAAGC
GCGAGGCGCAGCTTCACTTCGCCGGCACCGCGCCCGCGAGCGGCAACTTTGTGGCGCCGCACATCTTTGAACTCAGCCGC
GCCTCAGAGCTCACCGAGGAAGTGTTCGGCCCCATCCTGCACGTGGTGCGCTACAAGGCGGCGCAGTTCGACGATCTCCT
CAATGACATCGCCACGACCGGCTATGCGCTCACGCTCGGCGTGCAGTCGCGGATCGACGACACGATCGCGCGTGTGATCG
CGCGGCTTCCCACCGGCAATGTCTATGTGAATCGCAACATCATCGGCGCCGTGGTCGGCGTCCAGCCGTTCGGTGGCTCC
GGCCTGTCGGGCACCGGCCCCAAAGCCGGCGGCCCGCATTATCTGCCGCGGTTCGCACTGGAACAGACGGTGTCGATCAA
CACTGCCGCCGCCGGCGGCAATGCCGCTCTGCTGACAGGCAGCGAATAA

Upstream 100 bases:

>100_bases
GGCCCCGGCCGTGCCAATATGGCAGCCTGGATGGCATCGCATTTGCTGGCTGCACTGATGCGTGCCGTCCACAGCTATCT
GGCCTCGGGAGCCGACCGCC

Downstream 100 bases:

>100_bases
CGACCAACATTTTCAAAGCCTGCGCGTCGCCGGAAGACGTCCATGCAGGTTCCAATATTGCATCGTGCTGATAACCCGGT
TCATATGCGGAAGAAACCGG

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1002; Mature: 1001

Protein sequence:

>1002_residues
MPSDPPLAEFTAAYAPDDAALAAELLTTATLTPDREAQIDAIATDLITAIRGSEHGLRGVEAMLREFALSTKEGLALMVL
AEALLRVPDAATADAFIEDKLGQGDFAHHRIKSDAVLVNASAWALGLSARLVHAGETPQGTLAALTRRIGAPAVRAATRQ
AMRLIGNHFVLGETIDAALARAQPYAREGSRYSYDMLGEGARTAADAERYYQSYADAIIAIGRRAGNAALPARPGISVKL
SALHPRFEAISRDRVMRELTPRLLKLAQLAKSHDLAFTVDAEEADRLELSLEVFAACFADPSLKGWDGYGLAVQAYQKRA
ATVIDHVAELARAFDRRMMLRLVKGAYWDTEIKRTQERGLADYPVFTRKPMTDLNYLHCARKLLALRPHLFPQFASHNAL
TVATILAEAGDCDGYEFQRLHGMGEALYARLLADHPQAMCRIYAPVGGHSDLLAYLVRRLLENGANSSFVAQAGDDSVPI
AELLTRPATLIGHPENARNSAIPLPRDLYQPQRINSRGIEFGDRSALAALLGDIESARRPLPTVASTTPEQAAATVTAAR
KGFESWSRTSADHRAAILQRAGDLLEQRRGELIALLQDEGGKTLDDGVAEVREAVDYCRYYASEGRRLFGGPLVLPGPTG
ERNTLTLRGRGVFVAISPWNFPLAIFLGQITAALMAGNAVVAKPAEQTPVIAEVAVRLLHAAGVPPAALHLVQGDGRIGA
ALIEQRDIAGVVFTGSTEVARAINRTLAAKDGPIVPLIAETGGINAMIVDATALPEQVADDVIASAFRSAGQRCSALRLL
CVQDDVADRVIAMIAGAARELTIGDPRDPATHVGPVIDAEAKTRLETHIAAMKREAQLHFAGTAPASGNFVAPHIFELSR
ASELTEEVFGPILHVVRYKAAQFDDLLNDIATTGYALTLGVQSRIDDTIARVIARLPTGNVYVNRNIIGAVVGVQPFGGS
GLSGTGPKAGGPHYLPRFALEQTVSINTAAAGGNAALLTGSE

Sequences:

>Translated_1002_residues
MPSDPPLAEFTAAYAPDDAALAAELLTTATLTPDREAQIDAIATDLITAIRGSEHGLRGVEAMLREFALSTKEGLALMVL
AEALLRVPDAATADAFIEDKLGQGDFAHHRIKSDAVLVNASAWALGLSARLVHAGETPQGTLAALTRRIGAPAVRAATRQ
AMRLIGNHFVLGETIDAALARAQPYAREGSRYSYDMLGEGARTAADAERYYQSYADAIIAIGRRAGNAALPARPGISVKL
SALHPRFEAISRDRVMRELTPRLLKLAQLAKSHDLAFTVDAEEADRLELSLEVFAACFADPSLKGWDGYGLAVQAYQKRA
ATVIDHVAELARAFDRRMMLRLVKGAYWDTEIKRTQERGLADYPVFTRKPMTDLNYLHCARKLLALRPHLFPQFASHNAL
TVATILAEAGDCDGYEFQRLHGMGEALYARLLADHPQAMCRIYAPVGGHSDLLAYLVRRLLENGANSSFVAQAGDDSVPI
AELLTRPATLIGHPENARNSAIPLPRDLYQPQRINSRGIEFGDRSALAALLGDIESARRPLPTVASTTPEQAAATVTAAR
KGFESWSRTSADHRAAILQRAGDLLEQRRGELIALLQDEGGKTLDDGVAEVREAVDYCRYYASEGRRLFGGPLVLPGPTG
ERNTLTLRGRGVFVAISPWNFPLAIFLGQITAALMAGNAVVAKPAEQTPVIAEVAVRLLHAAGVPPAALHLVQGDGRIGA
ALIEQRDIAGVVFTGSTEVARAINRTLAAKDGPIVPLIAETGGINAMIVDATALPEQVADDVIASAFRSAGQRCSALRLL
CVQDDVADRVIAMIAGAARELTIGDPRDPATHVGPVIDAEAKTRLETHIAAMKREAQLHFAGTAPASGNFVAPHIFELSR
ASELTEEVFGPILHVVRYKAAQFDDLLNDIATTGYALTLGVQSRIDDTIARVIARLPTGNVYVNRNIIGAVVGVQPFGGS
GLSGTGPKAGGPHYLPRFALEQTVSINTAAAGGNAALLTGSE
>Mature_1001_residues
PSDPPLAEFTAAYAPDDAALAAELLTTATLTPDREAQIDAIATDLITAIRGSEHGLRGVEAMLREFALSTKEGLALMVLA
EALLRVPDAATADAFIEDKLGQGDFAHHRIKSDAVLVNASAWALGLSARLVHAGETPQGTLAALTRRIGAPAVRAATRQA
MRLIGNHFVLGETIDAALARAQPYAREGSRYSYDMLGEGARTAADAERYYQSYADAIIAIGRRAGNAALPARPGISVKLS
ALHPRFEAISRDRVMRELTPRLLKLAQLAKSHDLAFTVDAEEADRLELSLEVFAACFADPSLKGWDGYGLAVQAYQKRAA
TVIDHVAELARAFDRRMMLRLVKGAYWDTEIKRTQERGLADYPVFTRKPMTDLNYLHCARKLLALRPHLFPQFASHNALT
VATILAEAGDCDGYEFQRLHGMGEALYARLLADHPQAMCRIYAPVGGHSDLLAYLVRRLLENGANSSFVAQAGDDSVPIA
ELLTRPATLIGHPENARNSAIPLPRDLYQPQRINSRGIEFGDRSALAALLGDIESARRPLPTVASTTPEQAAATVTAARK
GFESWSRTSADHRAAILQRAGDLLEQRRGELIALLQDEGGKTLDDGVAEVREAVDYCRYYASEGRRLFGGPLVLPGPTGE
RNTLTLRGRGVFVAISPWNFPLAIFLGQITAALMAGNAVVAKPAEQTPVIAEVAVRLLHAAGVPPAALHLVQGDGRIGAA
LIEQRDIAGVVFTGSTEVARAINRTLAAKDGPIVPLIAETGGINAMIVDATALPEQVADDVIASAFRSAGQRCSALRLLC
VQDDVADRVIAMIAGAARELTIGDPRDPATHVGPVIDAEAKTRLETHIAAMKREAQLHFAGTAPASGNFVAPHIFELSRA
SELTEEVFGPILHVVRYKAAQFDDLLNDIATTGYALTLGVQSRIDDTIARVIARLPTGNVYVNRNIIGAVVGVQPFGGSG
LSGTGPKAGGPHYLPRFALEQTVSINTAAAGGNAALLTGSE

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=443, Percent_Identity=31.1512415349887, Blast_Score=176, Evalue=9e-44,
Organism=Homo sapiens, GI153266822, Length=448, Percent_Identity=30.8035714285714, Blast_Score=175, Evalue=2e-43,
Organism=Homo sapiens, GI25777736, Length=444, Percent_Identity=31.981981981982, Blast_Score=174, Evalue=5e-43,
Organism=Homo sapiens, GI25777734, Length=444, Percent_Identity=31.981981981982, Blast_Score=174, Evalue=5e-43,
Organism=Homo sapiens, GI238859541, Length=444, Percent_Identity=31.981981981982, Blast_Score=173, Evalue=6e-43,
Organism=Homo sapiens, GI25777732, Length=463, Percent_Identity=29.8056155507559, Blast_Score=171, Evalue=4e-42,
Organism=Homo sapiens, GI25777730, Length=458, Percent_Identity=30.1310043668122, Blast_Score=161, Evalue=3e-39,
Organism=Homo sapiens, GI25777724, Length=427, Percent_Identity=30.2107728337237, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI12007648, Length=453, Percent_Identity=28.6975717439294, Blast_Score=156, Evalue=8e-38,
Organism=Homo sapiens, GI25777728, Length=409, Percent_Identity=29.8288508557457, Blast_Score=151, Evalue=4e-36,
Organism=Homo sapiens, GI115387104, Length=443, Percent_Identity=27.0880361173815, Blast_Score=150, Evalue=5e-36,
Organism=Homo sapiens, GI21614513, Length=482, Percent_Identity=28.0082987551867, Blast_Score=150, Evalue=6e-36,
Organism=Homo sapiens, GI4507229, Length=429, Percent_Identity=29.1375291375291, Blast_Score=150, Evalue=6e-36,
Organism=Homo sapiens, GI238814322, Length=441, Percent_Identity=29.0249433106576, Blast_Score=148, Evalue=3e-35,
Organism=Homo sapiens, GI188035924, Length=463, Percent_Identity=27.4298056155508, Blast_Score=142, Evalue=2e-33,
Organism=Homo sapiens, GI25777721, Length=442, Percent_Identity=28.7330316742081, Blast_Score=141, Evalue=3e-33,
Organism=Homo sapiens, GI310128093, Length=446, Percent_Identity=27.8026905829596, Blast_Score=141, Evalue=4e-33,
Organism=Homo sapiens, GI310128103, Length=446, Percent_Identity=27.8026905829596, Blast_Score=140, Evalue=7e-33,
Organism=Homo sapiens, GI25777726, Length=426, Percent_Identity=27.4647887323944, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI11095441, Length=363, Percent_Identity=26.7217630853994, Blast_Score=121, Evalue=3e-27,
Organism=Homo sapiens, GI310128091, Length=385, Percent_Identity=28.3116883116883, Blast_Score=120, Evalue=9e-27,
Organism=Homo sapiens, GI25952152, Length=442, Percent_Identity=28.0542986425339, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI4502043, Length=417, Percent_Identity=26.1390887290168, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI238814371, Length=417, Percent_Identity=26.1390887290168, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI71773324, Length=318, Percent_Identity=27.3584905660377, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI73695881, Length=322, Percent_Identity=26.0869565217391, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI73695879, Length=322, Percent_Identity=26.0869565217391, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI310128087, Length=250, Percent_Identity=30.4, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI206597441, Length=425, Percent_Identity=24.9411764705882, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI206597439, Length=425, Percent_Identity=24.9411764705882, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI22907049, Length=425, Percent_Identity=24.9411764705882, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI4557303, Length=327, Percent_Identity=24.4648318042813, Blast_Score=94, Evalue=7e-19,
Organism=Homo sapiens, GI73466520, Length=327, Percent_Identity=24.4648318042813, Blast_Score=94, Evalue=8e-19,
Organism=Homo sapiens, GI310128101, Length=208, Percent_Identity=29.3269230769231, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI310128099, Length=217, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=5e-17,
Organism=Homo sapiens, GI310128089, Length=322, Percent_Identity=26.0869565217391, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI310128095, Length=310, Percent_Identity=25.8064516129032, Blast_Score=80, Evalue=8e-15,
Organism=Homo sapiens, GI301500698, Length=277, Percent_Identity=25.2707581227437, Blast_Score=77, Evalue=7e-14,
Organism=Homo sapiens, GI310128097, Length=247, Percent_Identity=27.5303643724696, Blast_Score=71, Evalue=6e-12,
Organism=Escherichia coli, GI1787250, Length=1043, Percent_Identity=47.1716203259827, Blast_Score=844, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=448, Percent_Identity=33.7053571428571, Blast_Score=189, Evalue=1e-48,
Organism=Escherichia coli, GI1788042, Length=427, Percent_Identity=32.5526932084309, Blast_Score=174, Evalue=3e-44,
Organism=Escherichia coli, GI1787558, Length=462, Percent_Identity=31.6017316017316, Blast_Score=165, Evalue=1e-41,
Organism=Escherichia coli, GI87081896, Length=443, Percent_Identity=31.3769751693002, Blast_Score=162, Evalue=1e-40,
Organism=Escherichia coli, GI1787684, Length=433, Percent_Identity=29.5612009237875, Blast_Score=152, Evalue=8e-38,
Organism=Escherichia coli, GI87081926, Length=433, Percent_Identity=27.2517321016166, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI1786504, Length=445, Percent_Identity=28.314606741573, Blast_Score=130, Evalue=4e-31,
Organism=Escherichia coli, GI87082295, Length=451, Percent_Identity=29.9334811529933, Blast_Score=128, Evalue=2e-30,
Organism=Escherichia coli, GI1787715, Length=441, Percent_Identity=29.2517006802721, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1787653, Length=377, Percent_Identity=23.6074270557029, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17534447, Length=466, Percent_Identity=31.5450643776824, Blast_Score=180, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI25143874, Length=463, Percent_Identity=28.5097192224622, Blast_Score=172, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI25143876, Length=463, Percent_Identity=28.5097192224622, Blast_Score=172, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI115534176, Length=493, Percent_Identity=30.8316430020284, Blast_Score=172, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI115532534, Length=357, Percent_Identity=33.6134453781513, Blast_Score=167, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17534119, Length=437, Percent_Identity=30.2059496567506, Blast_Score=164, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17551164, Length=509, Percent_Identity=27.5049115913556, Blast_Score=159, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI133930964, Length=509, Percent_Identity=28.6836935166994, Blast_Score=157, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17562198, Length=457, Percent_Identity=30.6345733041575, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI25144435, Length=466, Percent_Identity=30.4721030042918, Blast_Score=152, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI32564736, Length=431, Percent_Identity=30.8584686774942, Blast_Score=145, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71995606, Length=423, Percent_Identity=29.5508274231678, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71986308, Length=410, Percent_Identity=27.8048780487805, Blast_Score=131, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI32564151, Length=412, Percent_Identity=28.8834951456311, Blast_Score=130, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71995613, Length=380, Percent_Identity=28.4210526315789, Blast_Score=125, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI25146391, Length=336, Percent_Identity=25, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32566756, Length=336, Percent_Identity=25, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI25146394, Length=336, Percent_Identity=25, Blast_Score=94, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71990744, Length=298, Percent_Identity=28.8590604026846, Blast_Score=94, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17564084, Length=422, Percent_Identity=23.4597156398104, Blast_Score=91, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6323822, Length=451, Percent_Identity=30.1552106430155, Blast_Score=167, Evalue=8e-42,
Organism=Saccharomyces cerevisiae, GI6323821, Length=450, Percent_Identity=30, Blast_Score=162, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6320917, Length=446, Percent_Identity=29.1479820627803, Blast_Score=159, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6324950, Length=423, Percent_Identity=28.3687943262411, Blast_Score=157, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6319478, Length=451, Percent_Identity=27.9379157427938, Blast_Score=153, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6321826, Length=441, Percent_Identity=28.3446712018141, Blast_Score=150, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6325196, Length=495, Percent_Identity=26.4646464646465, Blast_Score=144, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6321828, Length=478, Percent_Identity=26.1506276150628, Blast_Score=95, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6323757, Length=338, Percent_Identity=24.8520710059172, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281362580, Length=445, Percent_Identity=31.2359550561798, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI62472918, Length=445, Percent_Identity=31.2359550561798, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI62472926, Length=445, Percent_Identity=31.2359550561798, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI62472936, Length=445, Percent_Identity=31.2359550561798, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI21356737, Length=445, Percent_Identity=31.2359550561798, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24668425, Length=435, Percent_Identity=30.1149425287356, Blast_Score=173, Evalue=6e-43,
Organism=Drosophila melanogaster, GI24668417, Length=435, Percent_Identity=30.1149425287356, Blast_Score=173, Evalue=6e-43,
Organism=Drosophila melanogaster, GI24668413, Length=435, Percent_Identity=30.1149425287356, Blast_Score=173, Evalue=6e-43,
Organism=Drosophila melanogaster, GI20129399, Length=453, Percent_Identity=29.5805739514349, Blast_Score=163, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24650465, Length=424, Percent_Identity=28.3018867924528, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24585660, Length=476, Percent_Identity=26.890756302521, Blast_Score=144, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24666674, Length=465, Percent_Identity=26.0215053763441, Blast_Score=138, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28571798, Length=437, Percent_Identity=28.604118993135, Blast_Score=133, Evalue=5e-31,
Organism=Drosophila melanogaster, GI28571796, Length=437, Percent_Identity=28.604118993135, Blast_Score=133, Evalue=5e-31,
Organism=Drosophila melanogaster, GI28571794, Length=437, Percent_Identity=28.604118993135, Blast_Score=133, Evalue=5e-31,
Organism=Drosophila melanogaster, GI28571806, Length=439, Percent_Identity=28.4738041002278, Blast_Score=133, Evalue=6e-31,
Organism=Drosophila melanogaster, GI28574525, Length=460, Percent_Identity=26.9565217391304, Blast_Score=133, Evalue=6e-31,
Organism=Drosophila melanogaster, GI28571802, Length=437, Percent_Identity=28.604118993135, Blast_Score=133, Evalue=6e-31,
Organism=Drosophila melanogaster, GI28571800, Length=437, Percent_Identity=28.604118993135, Blast_Score=133, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24638876, Length=421, Percent_Identity=28.2660332541568, Blast_Score=119, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24638878, Length=421, Percent_Identity=28.2660332541568, Blast_Score=118, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281360299, Length=326, Percent_Identity=26.9938650306748, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281360297, Length=326, Percent_Identity=26.9938650306748, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281360295, Length=326, Percent_Identity=26.9938650306748, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24586250, Length=326, Percent_Identity=26.9938650306748, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45552499, Length=326, Percent_Identity=26.6871165644172, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281360303, Length=322, Percent_Identity=26.7080745341615, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281360301, Length=322, Percent_Identity=27.0186335403727, Blast_Score=99, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 106960; Mature: 106829

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSDPPLAEFTAAYAPDDAALAAELLTTATLTPDREAQIDAIATDLITAIRGSEHGLRGV
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHH
EAMLREFALSTKEGLALMVLAEALLRVPDAATADAFIEDKLGQGDFAHHRIKSDAVLVNA
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHCCCCEEEEEC
SAWALGLSARLVHAGETPQGTLAALTRRIGAPAVRAATRQAMRLIGNHFVLGETIDAALA
CHHHHHHHHEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEECHHHHHHHH
RAQPYAREGSRYSYDMLGEGARTAADAERYYQSYADAIIAIGRRAGNAALPARPGISVKL
HCCCHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
SALHPRFEAISRDRVMRELTPRLLKLAQLAKSHDLAFTVDAEEADRLELSLEVFAACFAD
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCC
PSLKGWDGYGLAVQAYQKRAATVIDHVAELARAFDRRMMLRLVKGAYWDTEIKRTQERGL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
ADYPVFTRKPMTDLNYLHCARKLLALRPHLFPQFASHNALTVATILAEAGDCDGYEFQRL
CCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHH
HGMGEALYARLLADHPQAMCRIYAPVGGHSDLLAYLVRRLLENGANSSFVAQAGDDSVPI
HCCHHHHHHHHHHHCCHHHHEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCH
AELLTRPATLIGHPENARNSAIPLPRDLYQPQRINSRGIEFGDRSALAALLGDIESARRP
HHHHCCCHHEECCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
LPTVASTTPEQAAATVTAARKGFESWSRTSADHRAAILQRAGDLLEQRRGELIALLQDEG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GKTLDDGVAEVREAVDYCRYYASEGRRLFGGPLVLPGPTGERNTLTLRGRGVFVAISPWN
CCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEECCCCCCCCEEEEECCEEEEEECCCC
FPLAIFLGQITAALMAGNAVVAKPAEQTPVIAEVAVRLLHAAGVPPAALHLVQGDGRIGA
CHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCHHHEEEEECCCCCHH
ALIEQRDIAGVVFTGSTEVARAINRTLAAKDGPIVPLIAETGGINAMIVDATALPEQVAD
HHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECHHCHHHHHH
DVIASAFRSAGQRCSALRLLCVQDDVADRVIAMIAGAARELTIGDPRDPATHVGPVIDAE
HHHHHHHHHHHHHHHHHEEEHCCHHHHHHHHHHHHCCCCEEECCCCCCCCHHCCCCCCCH
AKTRLETHIAAMKREAQLHFAGTAPASGNFVAPHIFELSRASELTEEVFGPILHVVRYKA
HHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQFDDLLNDIATTGYALTLGVQSRIDDTIARVIARLPTGNVYVNRNIIGAVVGVQPFGGS
HHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHCCCCCEEECCCEEEEEEECCCCCCC
GLSGTGPKAGGPHYLPRFALEQTVSINTAAAGGNAALLTGSE
CCCCCCCCCCCCCCCHHHHHHHHHEEEEECCCCCEEEEECCC
>Mature Secondary Structure 
PSDPPLAEFTAAYAPDDAALAAELLTTATLTPDREAQIDAIATDLITAIRGSEHGLRGV
CCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHH
EAMLREFALSTKEGLALMVLAEALLRVPDAATADAFIEDKLGQGDFAHHRIKSDAVLVNA
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHCCCCEEEEEC
SAWALGLSARLVHAGETPQGTLAALTRRIGAPAVRAATRQAMRLIGNHFVLGETIDAALA
CHHHHHHHHEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEECHHHHHHHH
RAQPYAREGSRYSYDMLGEGARTAADAERYYQSYADAIIAIGRRAGNAALPARPGISVKL
HCCCHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
SALHPRFEAISRDRVMRELTPRLLKLAQLAKSHDLAFTVDAEEADRLELSLEVFAACFAD
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCC
PSLKGWDGYGLAVQAYQKRAATVIDHVAELARAFDRRMMLRLVKGAYWDTEIKRTQERGL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
ADYPVFTRKPMTDLNYLHCARKLLALRPHLFPQFASHNALTVATILAEAGDCDGYEFQRL
CCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHH
HGMGEALYARLLADHPQAMCRIYAPVGGHSDLLAYLVRRLLENGANSSFVAQAGDDSVPI
HCCHHHHHHHHHHHCCHHHHEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCH
AELLTRPATLIGHPENARNSAIPLPRDLYQPQRINSRGIEFGDRSALAALLGDIESARRP
HHHHCCCHHEECCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
LPTVASTTPEQAAATVTAARKGFESWSRTSADHRAAILQRAGDLLEQRRGELIALLQDEG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GKTLDDGVAEVREAVDYCRYYASEGRRLFGGPLVLPGPTGERNTLTLRGRGVFVAISPWN
CCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEECCCCCCCCEEEEECCEEEEEECCCC
FPLAIFLGQITAALMAGNAVVAKPAEQTPVIAEVAVRLLHAAGVPPAALHLVQGDGRIGA
CHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCHHHEEEEECCCCCHH
ALIEQRDIAGVVFTGSTEVARAINRTLAAKDGPIVPLIAETGGINAMIVDATALPEQVAD
HHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECHHCHHHHHH
DVIASAFRSAGQRCSALRLLCVQDDVADRVIAMIAGAARELTIGDPRDPATHVGPVIDAE
HHHHHHHHHHHHHHHHHEEEHCCHHHHHHHHHHHHCCCCEEECCCCCCCCHHCCCCCCCH
AKTRLETHIAAMKREAQLHFAGTAPASGNFVAPHIFELSRASELTEEVFGPILHVVRYKA
HHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQFDDLLNDIATTGYALTLGVQSRIDDTIARVIARLPTGNVYVNRNIIGAVVGVQPFGGS
HHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHCCCCCEEECCCEEEEEEECCCCCCC
GLSGTGPKAGGPHYLPRFALEQTVSINTAAAGGNAALLTGSE
CCCCCCCCCCCCCCCHHHHHHHHHEEEEECCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]