Click here to switch to the map view.

The map label for this gene is groES

Identifier: 192289742

GI number: 192289742

Start: 1405002

End: 1405298

Strand: Reverse

Name: groES

Synonym: Rpal_1332

Alternate gene names: 192289742

Gene position: 1405298-1405002 (Counterclockwise)

Preceding gene: 192289745

Following gene: 192289741

Centisome position: 24.47

GC content: 61.28

Gene sequence:

>297_bases
ATGGCTAAAATCAATTTTCGTCCTCTCCATGACCGTGTCGTGGTGAAGCGTATCGACGCCGAAACCAAGACCAAGGGCGG
CATCATCATCCCGGACTCCGCCAAGGAGAAGCCGCAGGAAGGTCAGGTGATCGCCGTCGGCCCGGGCGGCCGCGACGAGA
CCGGCAAGCTGACCCCGATCGACGTCAAGGTCGGCGATCGCGTGCTGTTCGGCAAGTGGTCGGGCACCGAGATCAAGCTG
GACGGCGAAGAACTCCTGATCATGAAGGAGTCGGACATCATGGGCGTGGTCGGCTGA

Upstream 100 bases:

>100_bases
TCTTGCAGTACGACTGCCAACACGCGGACGCGAACACGAGCCGCGATCACGAACCGGCACTCGAACGCCAAAGCCCCTCC
AGCAACGCACAGGATAGCCC

Downstream 100 bases:

>100_bases
GCCGCATCGCGACAGTATCGAGATATCAGGAGCGAATGAATGGCTGCTAAAGACGTCAAGTTTGCCGGCGATGCCCGCGA
CCGCATGCTGCGCGGCGTGG

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein 1; Protein Cpn10 1

Number of amino acids: Translated: 98; Mature: 97

Protein sequence:

>98_residues
MAKINFRPLHDRVVVKRIDAETKTKGGIIIPDSAKEKPQEGQVIAVGPGGRDETGKLTPIDVKVGDRVLFGKWSGTEIKL
DGEELLIMKESDIMGVVG

Sequences:

>Translated_98_residues
MAKINFRPLHDRVVVKRIDAETKTKGGIIIPDSAKEKPQEGQVIAVGPGGRDETGKLTPIDVKVGDRVLFGKWSGTEIKL
DGEELLIMKESDIMGVVG
>Mature_97_residues
AKINFRPLHDRVVVKRIDAETKTKGGIIIPDSAKEKPQEGQVIAVGPGGRDETGKLTPIDVKVGDRVLFGKWSGTEIKLD
GEELLIMKESDIMGVVG

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Homo sapiens, GI4504523, Length=91, Percent_Identity=42.8571428571429, Blast_Score=74, Evalue=2e-14,
Organism=Homo sapiens, GI169210012, Length=91, Percent_Identity=39.5604395604396, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790585, Length=95, Percent_Identity=52.6315789473684, Blast_Score=96, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17555568, Length=92, Percent_Identity=46.7391304347826, Blast_Score=93, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324594, Length=89, Percent_Identity=40.4494382022472, Blast_Score=72, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356029, Length=91, Percent_Identity=49.4505494505495, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21358317, Length=90, Percent_Identity=40, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH101_RHOPA (P60366)

Other databases:

- EMBL:   BX572596
- RefSeq:   NP_946492.1
- ProteinModelPortal:   P60366
- SMR:   P60366
- GeneID:   2691610
- GenomeReviews:   BX571963_GR
- KEGG:   rpa:RPA1141
- NMPDR:   fig|258594.1.peg.1136
- HOGENOM:   HBG703377
- OMA:   VEYMVLE
- ProtClustDB:   PRK00364
- BioCyc:   RPAL258594:RPA1141-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10625; Mature: 10493

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKINFRPLHDRVVVKRIDAETKTKGGIIIPDSAKEKPQEGQVIAVGPGGRDETGKLTPI
CCCCCCEECCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEE
DVKVGDRVLFGKWSGTEIKLDGEELLIMKESDIMGVVG
EEEECCEEEEECCCCCEEEECCCEEEEEECCCEEEECC
>Mature Secondary Structure 
AKINFRPLHDRVVVKRIDAETKTKGGIIIPDSAKEKPQEGQVIAVGPGGRDETGKLTPI
CCCCCEECCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEE
DVKVGDRVLFGKWSGTEIKLDGEELLIMKESDIMGVVG
EEEECCEEEEECCCCCEEEECCCEEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA