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The map label for this gene is atpB2 [H]

Identifier: 192289478

GI number: 192289478

Start: 1122719

End: 1123417

Strand: Reverse

Name: atpB2 [H]

Synonym: Rpal_1053

Alternate gene names: 192289478

Gene position: 1123417-1122719 (Counterclockwise)

Preceding gene: 192289479

Following gene: 192289477

Centisome position: 19.56

GC content: 62.23

Gene sequence:

>699_bases
GTGACTTCACCGCTCAGCAGCATCGCGCTGTTCAATTTGGGGCCGATACCGATCAGCGCTGGCGTGGTGGTCACCTGGGC
GATCATGGTGGCGCTGGTTCTGGGGAGCATTCTGGTCACGCGCCGCCCCTGGCTCGTGCCGTCGGCAGCCCAGGCGGCCT
TCGAGCTGATCGTCGATACCGTGGACGGCCAGATCCGCGATACCATGCAGATCGAACCCGCTCCTTATCGCGCCTTCATC
GGCACCCTGTTCGTCTTCATTTTCGTAGCCAACTGGTCCTCGCTGGTGCCCGGCGTCGCCCCCCCGACGGCTCAGCTCGA
GACCGATGCCGCGCTCGCTGTTCTGGTGTTCTTGGCGGTGATCTGGTTCGGCATACGCGTCGGCGGCGTGCGGGGCTATC
TGTCGACCTTCGCCTCGCCCAACCCGATCATGATCCCGCTCAATTTCATCGAAAGTCTGACCCGGACCTTCTCGCTGCTG
GTGCGGCTGTTCGGCAATGTGATGAGCGGCGTATTCGTGATCGGGATCGTATTGTCGCTCGCGGGCCTTCTCGTGCCGAT
CCCGCTGATGGCGCTCGATCTACTGACCGGTGCGGTGCAAGCCTACATTTTCTCGGTTCTGGCGATGGTGTTCATTGCCG
GTGCGGTGAACGAAGGACGACCGGACAGCAACAACTCCAGCCAAAGGATGCCCTCATGA

Upstream 100 bases:

>100_bases
CATTGGCGAGCCTGCAGGGTGCGCTGCCGCTGCTTGTGCTGGCACTTGGCGTCCTGGCCGCCCGGGCCGCCATCCTGCGT
CGCGTTCGAGAGGTCACTCC

Downstream 100 bases:

>100_bases
ACTGGTTAGCTTTCATCAGCATCGTATCGGCCGCTCTGGCGGTCTCGTTTGGAGCGATCGGCCCTGCCCTTGCCGAGGGG
CGCGCGGTCGCGGCCGCAAT

Product: F0F1 ATP synthase subunit A

Products: ATP; H+; H2O [C]

Alternate protein names: ATP synthase F0 sector subunit a 2; F-ATPase subunit 6 2 [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MTSPLSSIALFNLGPIPISAGVVVTWAIMVALVLGSILVTRRPWLVPSAAQAAFELIVDTVDGQIRDTMQIEPAPYRAFI
GTLFVFIFVANWSSLVPGVAPPTAQLETDAALAVLVFLAVIWFGIRVGGVRGYLSTFASPNPIMIPLNFIESLTRTFSLL
VRLFGNVMSGVFVIGIVLSLAGLLVPIPLMALDLLTGAVQAYIFSVLAMVFIAGAVNEGRPDSNNSSQRMPS

Sequences:

>Translated_232_residues
MTSPLSSIALFNLGPIPISAGVVVTWAIMVALVLGSILVTRRPWLVPSAAQAAFELIVDTVDGQIRDTMQIEPAPYRAFI
GTLFVFIFVANWSSLVPGVAPPTAQLETDAALAVLVFLAVIWFGIRVGGVRGYLSTFASPNPIMIPLNFIESLTRTFSLL
VRLFGNVMSGVFVIGIVLSLAGLLVPIPLMALDLLTGAVQAYIFSVLAMVFIAGAVNEGRPDSNNSSQRMPS
>Mature_231_residues
TSPLSSIALFNLGPIPISAGVVVTWAIMVALVLGSILVTRRPWLVPSAAQAAFELIVDTVDGQIRDTMQIEPAPYRAFIG
TLFVFIFVANWSSLVPGVAPPTAQLETDAALAVLVFLAVIWFGIRVGGVRGYLSTFASPNPIMIPLNFIESLTRTFSLLV
RLFGNVMSGVFVIGIVLSLAGLLVPIPLMALDLLTGAVQAYIFSVLAMVFIAGAVNEGRPDSNNSSQRMPS

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=200, Percent_Identity=25.5, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14 [C]

Molecular weight: Translated: 24676; Mature: 24544

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPLSSIALFNLGPIPISAGVVVTWAIMVALVLGSILVTRRPWLVPSAAQAAFELIVDT
CCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
VDGQIRDTMQIEPAPYRAFIGTLFVFIFVANWSSLVPGVAPPTAQLETDAALAVLVFLAV
HCCHHHHCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
IWFGIRVGGVRGYLSTFASPNPIMIPLNFIESLTRTFSLLVRLFGNVMSGVFVIGIVLSL
HHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLLVPIPLMALDLLTGAVQAYIFSVLAMVFIAGAVNEGRPDSNNSSQRMPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSPLSSIALFNLGPIPISAGVVVTWAIMVALVLGSILVTRRPWLVPSAAQAAFELIVDT
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
VDGQIRDTMQIEPAPYRAFIGTLFVFIFVANWSSLVPGVAPPTAQLETDAALAVLVFLAV
HCCHHHHCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
IWFGIRVGGVRGYLSTFASPNPIMIPLNFIESLTRTFSLLVRLFGNVMSGVFVIGIVLSL
HHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLLVPIPLMALDLLTGAVQAYIFSVLAMVFIAGAVNEGRPDSNNSSQRMPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ADP; H+; Phosphate [C]

Specific reaction: ADP + (4) H+ + Phosphate <==> ATP + (3) H+ + H2O [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA