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The map label for this gene is 192289451

Identifier: 192289451

GI number: 192289451

Start: 1087613

End: 1088542

Strand: Reverse

Name: 192289451

Synonym: Rpal_1024

Alternate gene names: NA

Gene position: 1088542-1087613 (Counterclockwise)

Preceding gene: 192289452

Following gene: 192289450

Centisome position: 18.95

GC content: 65.81

Gene sequence:

>930_bases
ATGACCACGCTTTTTCTGACCCATTCCGCGTGCCTCGACCATCACACGCCGGAAGGACATCCTGAGCGCGCTGCGCGGCT
CGTCGCCATCAACAAGACGCTCGGTGAAGAACGCTTTGCACCGCTGGCGCGCGCGGAGTCGCCGATCGGCTCGCTCGAGC
ACATCGCGCTGTGCCACACCGATCACCACATCGTCGAGCTGCGCCACATGTCGCCGTCCACCGGCGTCGTCTATGTCGAC
GGCGACACCTCGATGTCGCCCGGCACGTTCGAAGCCGCGCTACGCGGCGTCGGCGGCTCGGTCGCCGCGGTGGACGCGGT
GATGAAAGGCGAGGCCGCCAACGCCTTCGTGGCCACCCGCCCACCGGGGCACCATGCCGAAATCACCAAGCCGATGGGGT
TCTGCTTCTTCGGCAATGCCGCGATCGCCGCGCGCTACGCCCAGCGGCAATACGGCATCGAGCGAGCCGCGGTGGTGGAT
TTCGACGTCCACCACGGCAACGGCACCCAGGACATCTTCTGGGGCGATCGCACCGTGATGTATTGCTCCACTCACCAGAT
GCCGCTGTTCCCGGGTACCGGCTCCCAGGGCGAGCGCGGCGAATATGACAATATCGTCAACGCGCCCCTCGCCTCCGAAG
ACGGGGGCACTGAGTTCCGGTTCGCGTTCGAACAACTGATCCTGCCCCAGCTCAAGCGGTTTTCGCCGGAATTGATCGTG
ATTTCGGCCGGTTTCGACGCCCATTACCGCGATCCCCTGGCCAGCCTGAACCTGCGCGCCGAAGATTTCGGCTGGGTCAC
CGAACGCCTGATGGAGGTCGCGGCCCAGACCGCCGGCGGGCGGATTGTCTCGGTCCTCGAGGGGGGATATGACCTCCAGG
GCCTGAGTGAATCGGTTGCGGCTCACGTCGGCGCCCTGATGGGCGCTTGA

Upstream 100 bases:

>100_bases
CGGCTGGCTAAGCCTTAAGCGGCCCTTTCGCTCGTCGCTGCGAATAACTACATTCATTCGAATAGATCGCAGACACAGAT
CGGCGCCCGGGCACTTCTGA

Downstream 100 bases:

>100_bases
ACCAGCCGCCCCGTCAGGCGACCAAGAACAACAACCAAAACAATGCTGCCGCGCCCCCGCGCGGTGCAGCTGGGAATGCG
AAATGGCCGAAGCCGCAACC

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTTLFLTHSACLDHHTPEGHPERAARLVAINKTLGEERFAPLARAESPIGSLEHIALCHTDHHIVELRHMSPSTGVVYVD
GDTSMSPGTFEAALRGVGGSVAAVDAVMKGEAANAFVATRPPGHHAEITKPMGFCFFGNAAIAARYAQRQYGIERAAVVD
FDVHHGNGTQDIFWGDRTVMYCSTHQMPLFPGTGSQGERGEYDNIVNAPLASEDGGTEFRFAFEQLILPQLKRFSPELIV
ISAGFDAHYRDPLASLNLRAEDFGWVTERLMEVAAQTAGGRIVSVLEGGYDLQGLSESVAAHVGALMGA

Sequences:

>Translated_309_residues
MTTLFLTHSACLDHHTPEGHPERAARLVAINKTLGEERFAPLARAESPIGSLEHIALCHTDHHIVELRHMSPSTGVVYVD
GDTSMSPGTFEAALRGVGGSVAAVDAVMKGEAANAFVATRPPGHHAEITKPMGFCFFGNAAIAARYAQRQYGIERAAVVD
FDVHHGNGTQDIFWGDRTVMYCSTHQMPLFPGTGSQGERGEYDNIVNAPLASEDGGTEFRFAFEQLILPQLKRFSPELIV
ISAGFDAHYRDPLASLNLRAEDFGWVTERLMEVAAQTAGGRIVSVLEGGYDLQGLSESVAAHVGALMGA
>Mature_308_residues
TTLFLTHSACLDHHTPEGHPERAARLVAINKTLGEERFAPLARAESPIGSLEHIALCHTDHHIVELRHMSPSTGVVYVDG
DTSMSPGTFEAALRGVGGSVAAVDAVMKGEAANAFVATRPPGHHAEITKPMGFCFFGNAAIAARYAQRQYGIERAAVVDF
DVHHGNGTQDIFWGDRTVMYCSTHQMPLFPGTGSQGERGEYDNIVNAPLASEDGGTEFRFAFEQLILPQLKRFSPELIVI
SAGFDAHYRDPLASLNLRAEDFGWVTERLMEVAAQTAGGRIVSVLEGGYDLQGLSESVAAHVGALMGA

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI30795204, Length=341, Percent_Identity=35.1906158357771, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI30795202, Length=341, Percent_Identity=35.1906158357771, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI17158039, Length=341, Percent_Identity=35.1906158357771, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI153085395, Length=247, Percent_Identity=40.4858299595142, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI13128864, Length=322, Percent_Identity=35.7142857142857, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI148539870, Length=350, Percent_Identity=34.8571428571429, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI169234807, Length=350, Percent_Identity=34.8571428571429, Blast_Score=158, Evalue=5e-39,
Organism=Homo sapiens, GI62750349, Length=348, Percent_Identity=33.0459770114943, Blast_Score=157, Evalue=8e-39,
Organism=Homo sapiens, GI62750347, Length=348, Percent_Identity=33.0459770114943, Blast_Score=157, Evalue=8e-39,
Organism=Homo sapiens, GI20070354, Length=316, Percent_Identity=35.126582278481, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI226529806, Length=316, Percent_Identity=31.9620253164557, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI8923769, Length=305, Percent_Identity=24.5901639344262, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI13128860, Length=264, Percent_Identity=26.1363636363636, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI293336691, Length=263, Percent_Identity=25.8555133079848, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI13128862, Length=272, Percent_Identity=25, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI262073088, Length=184, Percent_Identity=27.1739130434783, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI262073092, Length=216, Percent_Identity=26.3888888888889, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17540334, Length=307, Percent_Identity=36.8078175895765, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI193206283, Length=307, Percent_Identity=36.8078175895765, Blast_Score=188, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17540332, Length=307, Percent_Identity=36.8078175895765, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI193209491, Length=253, Percent_Identity=38.3399209486166, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI25154020, Length=244, Percent_Identity=33.6065573770492, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI25154022, Length=227, Percent_Identity=33.0396475770925, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17537347, Length=318, Percent_Identity=30.188679245283, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17534739, Length=314, Percent_Identity=26.4331210191083, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17508561, Length=301, Percent_Identity=25.5813953488372, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17561978, Length=222, Percent_Identity=26.5765765765766, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324307, Length=325, Percent_Identity=31.0769230769231, Blast_Score=150, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6325141, Length=319, Percent_Identity=29.153605015674, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323999, Length=303, Percent_Identity=24.0924092409241, Blast_Score=79, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6321244, Length=213, Percent_Identity=27.2300469483568, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6325325, Length=125, Percent_Identity=28.8, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281360899, Length=309, Percent_Identity=36.2459546925566, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24642144, Length=309, Percent_Identity=36.2459546925566, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24642146, Length=309, Percent_Identity=36.2459546925566, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24642142, Length=309, Percent_Identity=36.2459546925566, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI281360801, Length=345, Percent_Identity=33.0434782608696, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24641720, Length=345, Percent_Identity=33.0434782608696, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI281360799, Length=345, Percent_Identity=33.0434782608696, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24657891, Length=273, Percent_Identity=26.007326007326, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644244, Length=305, Percent_Identity=24.5901639344262, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33241; Mature: 33110

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLFLTHSACLDHHTPEGHPERAARLVAINKTLGEERFAPLARAESPIGSLEHIALCHT
CEEEEEEHHHHHCCCCCCCCHHHHEEEEEEHHHHCHHHHCHHHHCCCCCCCCCEEEEEEC
DHHIVELRHMSPSTGVVYVDGDTSMSPGTFEAALRGVGGSVAAVDAVMKGEAANAFVATR
CCEEEEEEECCCCCCEEEECCCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEEC
PPGHHAEITKPMGFCFFGNAAIAARYAQRQYGIERAAVVDFDVHHGNGTQDIFWGDRTVM
CCCCCCEECCCCCEEEECCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCEEEECCCEEE
YCSTHQMPLFPGTGSQGERGEYDNIVNAPLASEDGGTEFRFAFEQLILPQLKRFSPELIV
EEECCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
ISAGFDAHYRDPLASLNLRAEDFGWVTERLMEVAAQTAGGRIVSVLEGGYDLQGLSESVA
EECCCCCHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHH
AHVGALMGA
HHHHHHHCC
>Mature Secondary Structure 
TTLFLTHSACLDHHTPEGHPERAARLVAINKTLGEERFAPLARAESPIGSLEHIALCHT
EEEEEEHHHHHCCCCCCCCHHHHEEEEEEHHHHCHHHHCHHHHCCCCCCCCCEEEEEEC
DHHIVELRHMSPSTGVVYVDGDTSMSPGTFEAALRGVGGSVAAVDAVMKGEAANAFVATR
CCEEEEEEECCCCCCEEEECCCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEEC
PPGHHAEITKPMGFCFFGNAAIAARYAQRQYGIERAAVVDFDVHHGNGTQDIFWGDRTVM
CCCCCCEECCCCCEEEECCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCEEEECCCEEE
YCSTHQMPLFPGTGSQGERGEYDNIVNAPLASEDGGTEFRFAFEQLILPQLKRFSPELIV
EEECCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
ISAGFDAHYRDPLASLNLRAEDFGWVTERLMEVAAQTAGGRIVSVLEGGYDLQGLSESVA
EECCCCCHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHH
AHVGALMGA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]