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The map label for this gene is qorA [H]

Identifier: 192289412

GI number: 192289412

Start: 1051061

End: 1052059

Strand: Reverse

Name: qorA [H]

Synonym: Rpal_0985

Alternate gene names: 192289412

Gene position: 1052059-1051061 (Counterclockwise)

Preceding gene: 192289415

Following gene: 192289411

Centisome position: 18.32

GC content: 65.67

Gene sequence:

>999_bases
ATGGAACCGATCCCTTCGCAAATGACCGTGGTTGGGATCAGCAAGCCCGGCGGTCCCGAGGTCCTGCTGCCCGAGACGCG
GGACGTGCCGAAGCCCGGCCCCGGGGAAATCCTGGTGAAAGTGACGGCCGCCGGCGTCAATCGTCCCGATGTGGCACAGC
GCTCCGGCAGCTATCCGCCGCCGCCCGGTGCCAGCGATCTGCCGGGCCTGGAAATCGCCGGTGAAGTGGTGGCGCTCGGC
GACGGCGCCTCCCGGCACAAGCTCGGCGACAAGGTGATGTCGCTGGTGGCTGGTGGCGGCTACGCGGAATATTGCATCGC
CCAGGACTCGCAGGCGATGAAGGTACCGGCCGCCTATTCGATGATCGAAGCCGGCGCCACGCCCGAGACGCTGATGACGG
TGTGGCACAACTTGTTCGAGCGCGGCGGCCTGCAGCCCGGCGAAACGTTGCTGGTGCACGGCGGTTCGTCCGGTATCGGT
ACGATGGCGATCCAGCTCGCGGTCGCACTCGGATCGAAAGTGATCACCACCGTCGGCTCGCAGGACAAAGCCGACGCCTG
CCTCAAGCTCGGCGCCAGCCGCGCCATCAACTACAAGACCGAGGATTTCGTCGCGGCGGTGAAGGAAGCCACTGGCGGCA
AGGGCGTCGAGGTAATCCTCGACATGGTCGGCGGCGATTACATCGAGCGCAACTACGACGCCGCGGCGATGGACGGCCGC
ATCGTGCAGATCGCGTTCCTTGGCGGTGCCAAGGCCAACGTCAACTTCGTCAAGCTGATGACCAAGCGGCTTCACCACAC
CGGCTCGACGCTGCGGCCGCGCTCCAACGCCGACAAGGCCGCGATGGTCGCGGCGATCGAAGCCAAGGTGCTACCTCTGC
TCGAGCAGGGCCGGATCAAGCCGCTGATCGACGGCACCTTCGCGCTGCGGGACGCCGCCGATGCTCACCGGCGGATGGAA
ACCAGCCAACATATTGGCAAAATTGTGTTGACTGTGTGA

Upstream 100 bases:

>100_bases
CGTTCGTGATCCGCTGCGGTTGCCAGCCGCCCTCCGGCTGTCTAATCACAGCCTACTTCGCCAGATGACACCCACCCGCC
TCGCCAGCCAAGGAAAAATC

Downstream 100 bases:

>100_bases
GTGGGGCTACCCCGGGGGCCGGCGAGAGAGTCTATGTTTTCGCTCGCTTTCATGGCATCTATCCGGGGCTCGTGGCGCGC
GGGGCCGCGCCATTCGGACT

Product: NAD(P)H quinone oxidoreductase, PIG3 family

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MEPIPSQMTVVGISKPGGPEVLLPETRDVPKPGPGEILVKVTAAGVNRPDVAQRSGSYPPPPGASDLPGLEIAGEVVALG
DGASRHKLGDKVMSLVAGGGYAEYCIAQDSQAMKVPAAYSMIEAGATPETLMTVWHNLFERGGLQPGETLLVHGGSSGIG
TMAIQLAVALGSKVITTVGSQDKADACLKLGASRAINYKTEDFVAAVKEATGGKGVEVILDMVGGDYIERNYDAAAMDGR
IVQIAFLGGAKANVNFVKLMTKRLHHTGSTLRPRSNADKAAMVAAIEAKVLPLLEQGRIKPLIDGTFALRDAADAHRRME
TSQHIGKIVLTV

Sequences:

>Translated_332_residues
MEPIPSQMTVVGISKPGGPEVLLPETRDVPKPGPGEILVKVTAAGVNRPDVAQRSGSYPPPPGASDLPGLEIAGEVVALG
DGASRHKLGDKVMSLVAGGGYAEYCIAQDSQAMKVPAAYSMIEAGATPETLMTVWHNLFERGGLQPGETLLVHGGSSGIG
TMAIQLAVALGSKVITTVGSQDKADACLKLGASRAINYKTEDFVAAVKEATGGKGVEVILDMVGGDYIERNYDAAAMDGR
IVQIAFLGGAKANVNFVKLMTKRLHHTGSTLRPRSNADKAAMVAAIEAKVLPLLEQGRIKPLIDGTFALRDAADAHRRME
TSQHIGKIVLTV
>Mature_332_residues
MEPIPSQMTVVGISKPGGPEVLLPETRDVPKPGPGEILVKVTAAGVNRPDVAQRSGSYPPPPGASDLPGLEIAGEVVALG
DGASRHKLGDKVMSLVAGGGYAEYCIAQDSQAMKVPAAYSMIEAGATPETLMTVWHNLFERGGLQPGETLLVHGGSSGIG
TMAIQLAVALGSKVITTVGSQDKADACLKLGASRAINYKTEDFVAAVKEATGGKGVEVILDMVGGDYIERNYDAAAMDGR
IVQIAFLGGAKANVNFVKLMTKRLHHTGSTLRPRSNADKAAMVAAIEAKVLPLLEQGRIKPLIDGTFALRDAADAHRRME
TSQHIGKIVLTV

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=41.5151515151515, Blast_Score=244, Evalue=6e-65,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=41.5151515151515, Blast_Score=244, Evalue=6e-65,
Organism=Homo sapiens, GI194239674, Length=326, Percent_Identity=31.5950920245399, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI13236495, Length=326, Percent_Identity=31.5950920245399, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=29.903536977492, Blast_Score=141, Evalue=7e-34,
Organism=Homo sapiens, GI24308257, Length=344, Percent_Identity=27.906976744186, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI194239676, Length=327, Percent_Identity=30.5810397553517, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI41872631, Length=307, Percent_Identity=29.3159609120521, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI28557745, Length=331, Percent_Identity=33.8368580060423, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI47519420, Length=381, Percent_Identity=26.509186351706, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI197927207, Length=195, Percent_Identity=27.1794871794872, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=36.697247706422, Blast_Score=150, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17507255, Length=318, Percent_Identity=26.1006289308176, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI212642053, Length=314, Percent_Identity=27.0700636942675, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17536829, Length=225, Percent_Identity=28.8888888888889, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=336, Percent_Identity=27.3809523809524, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319621, Length=337, Percent_Identity=27.0029673590504, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6323961, Length=337, Percent_Identity=25.2225519287834, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6324486, Length=337, Percent_Identity=24.3323442136499, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24581345, Length=299, Percent_Identity=30.1003344481605, Blast_Score=117, Evalue=9e-27,
Organism=Drosophila melanogaster, GI221330659, Length=297, Percent_Identity=28.6195286195286, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI19920632, Length=297, Percent_Identity=28.6195286195286, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI45550423, Length=179, Percent_Identity=29.608938547486, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34636; Mature: 34636

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPIPSQMTVVGISKPGGPEVLLPETRDVPKPGPGEILVKVTAAGVNRPDVAQRSGSYPP
CCCCCCCEEEEEECCCCCCCEECCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHCCCCCC
PPGASDLPGLEIAGEVVALGDGASRHKLGDKVMSLVAGGGYAEYCIAQDSQAMKVPAAYS
CCCCCCCCCCEECCEEEEECCCCHHHHHHHHHHHHHHCCCHHEEEEECCCCCEECCHHHH
MIEAGATPETLMTVWHNLFERGGLQPGETLLVHGGSSGIGTMAIQLAVALGSKVITTVGS
HHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCHHEEECCC
QDKADACLKLGASRAINYKTEDFVAAVKEATGGKGVEVILDMVGGDYIERNYDAAAMDGR
CCHHHHHHHHCCHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHCCCCCCCCCCE
IVQIAFLGGAKANVNFVKLMTKRLHHTGSTLRPRSNADKAAMVAAIEAKVLPLLEQGRIK
EEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
PLIDGTFALRDAADAHRRMETSQHIGKIVLTV
EECCCHHHHHHHHHHHHHHHHHHHHCEEEEEC
>Mature Secondary Structure
MEPIPSQMTVVGISKPGGPEVLLPETRDVPKPGPGEILVKVTAAGVNRPDVAQRSGSYPP
CCCCCCCEEEEEECCCCCCCEECCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHCCCCCC
PPGASDLPGLEIAGEVVALGDGASRHKLGDKVMSLVAGGGYAEYCIAQDSQAMKVPAAYS
CCCCCCCCCCEECCEEEEECCCCHHHHHHHHHHHHHHCCCHHEEEEECCCCCEECCHHHH
MIEAGATPETLMTVWHNLFERGGLQPGETLLVHGGSSGIGTMAIQLAVALGSKVITTVGS
HHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCHHEEECCC
QDKADACLKLGASRAINYKTEDFVAAVKEATGGKGVEVILDMVGGDYIERNYDAAAMDGR
CCHHHHHHHHCCHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHCCCCCCCCCCE
IVQIAFLGGAKANVNFVKLMTKRLHHTGSTLRPRSNADKAAMVAAIEAKVLPLLEQGRIK
EEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
PLIDGTFALRDAADAHRRMETSQHIGKIVLTV
EECCCHHHHHHHHHHHHHHHHHHHHCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]