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The map label for this gene is hss [H]

Identifier: 192289361

GI number: 192289361

Start: 992855

End: 994285

Strand: Reverse

Name: hss [H]

Synonym: Rpal_0933

Alternate gene names: 192289361

Gene position: 994285-992855 (Counterclockwise)

Preceding gene: 192289362

Following gene: 192289353

Centisome position: 17.31

GC content: 63.52

Gene sequence:

>1431_bases
ATGTCGTCTACCTCGAAGATCCATGCCAAGATCACCGGCCCCATCGTGATGATCGGCTTCGGCTCGATCGGTAAGGGCGC
GCTGCCCCTGATCGAGCGTCACTTCGAGTACGACAAGAAGCGGTTCGTCATCATCGATCCGCACGAGGATGGCGAACTCG
CCAAGAAGCACGGCGTCCGCTTCATCAAGCAGGCGGTGACCAAGGACAACTACCGCGAGCTGCTGGTCCCGCTGCTGACC
GAAGGCGGCGGCCAGGGCTTCTGCGTCAACCTGTCGGTCGACACCGGCTCGGTCGACCTGATGACGATGTGCCGCGAGAT
CGGTGCTCTGTATATCGACACCGTCGTCGAGCCTTGGCTCGGCTTCTACTTCGACAAGAACGCCGGCCCGGAGAAGCGCT
CCAACTACGCGCTGCGCGAGACCCTGCTGGCCGCCAAGGCCAAGAACCCGGGCGGCACCACCGCGGTGTCGACCTGTGGT
GCCAATCCCGGCATGGTGTCGTGGTTCGTCAAGCAGGCGCTGCTCGACATCGCCCGCGATACCGGCCTCGAATTCAACGA
ACCGAAGAGCCGCGAAGGCTGGGGCCAGCTCGCGCAGAAGCTCGGCGTCAAGGGCATCCACATTGCCGAGCGTGATACTC
AGCGCGCCAAGACCCCGAAGCCGATGAACGTGTTCGTCAACACCTGGTCGGTGGAAGGCTTCGTGTCCGAAGGCCTGCAG
CCGGCCGAACTCGGCTGGGGCACGCACGAGAAGTGGATCCCCGACAACGGCCGCAAGCACACCGAAGGCTGCCAGGCTGC
GATCTATCTGCTGCAGCCCGGTGCCAACACCCGCGTCCGTACCTGGTGTCCAACTCCGGGTCCGCAGTACGGCTTCTTGG
TAACTCACAACGAGTCGATCTCGATCGCCGATTACTTCACGGTGCGCGACGGCCAGAACGTGGTGTACCGGCCGACCTGC
CACTACGCCTATCACCCGGCCAACGATGCGGTGCTGTCGCTGCACGAAATGTTCGGCGCCGAAGGCAAGATGCAGCCGAA
GTGGCACATCCTCGACGAGAACGAGATCGTCGACGGCATCGACGAACTCGGCGTACTGGTCTACGGCCACGCCAAGAACG
CCTACTGGTACGGCTCGCAGCTCTCGATCGAAGAAACCCGCGAGATCTGCCCGTATCAGAACGCCACCGGCATGCAGGTG
TCGTCGGCGGTGCTGGCCGGCATGGTATGGGCGCTGGAGAATCCGGAAGCCGGCATCGTCGAAGCCGACGAGATGGACTT
CCGCCGCTGCCTCGAAGTGCAGAAGCCGTATCTCGGCCCGGTGAAGGGCTACTACACCGATTGGACCCCGCTCACCGACC
GCCCCGGCCTGTTCCCGGAGGACATCGACACCTCCGATCCGTGGCAGTTCAAGAACGTCCTGGTGCGCTGA

Upstream 100 bases:

>100_bases
GCAGGTGACATCTGAAATTCACCTCGCCGTCACATTCCCGAACTGTCCTGCCCGCACATAGCGGCCTCATCACTGCCACC
CTGTCCGGAGTTCAAACCTG

Downstream 100 bases:

>100_bases
GGCGCCGAACGGCCTTTGAACGGACAGCCTTCGCGTTGTCCGGTTCCTGCCCGAACACCGCGGGATTCCGGGTTCGCGAG
CTGCGCTCGCGCCCCGGAAT

Product: Homospermidine synthase

Products: NA

Alternate protein names: HSS [H]

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MSSTSKIHAKITGPIVMIGFGSIGKGALPLIERHFEYDKKRFVIIDPHEDGELAKKHGVRFIKQAVTKDNYRELLVPLLT
EGGGQGFCVNLSVDTGSVDLMTMCREIGALYIDTVVEPWLGFYFDKNAGPEKRSNYALRETLLAAKAKNPGGTTAVSTCG
ANPGMVSWFVKQALLDIARDTGLEFNEPKSREGWGQLAQKLGVKGIHIAERDTQRAKTPKPMNVFVNTWSVEGFVSEGLQ
PAELGWGTHEKWIPDNGRKHTEGCQAAIYLLQPGANTRVRTWCPTPGPQYGFLVTHNESISIADYFTVRDGQNVVYRPTC
HYAYHPANDAVLSLHEMFGAEGKMQPKWHILDENEIVDGIDELGVLVYGHAKNAYWYGSQLSIEETREICPYQNATGMQV
SSAVLAGMVWALENPEAGIVEADEMDFRRCLEVQKPYLGPVKGYYTDWTPLTDRPGLFPEDIDTSDPWQFKNVLVR

Sequences:

>Translated_476_residues
MSSTSKIHAKITGPIVMIGFGSIGKGALPLIERHFEYDKKRFVIIDPHEDGELAKKHGVRFIKQAVTKDNYRELLVPLLT
EGGGQGFCVNLSVDTGSVDLMTMCREIGALYIDTVVEPWLGFYFDKNAGPEKRSNYALRETLLAAKAKNPGGTTAVSTCG
ANPGMVSWFVKQALLDIARDTGLEFNEPKSREGWGQLAQKLGVKGIHIAERDTQRAKTPKPMNVFVNTWSVEGFVSEGLQ
PAELGWGTHEKWIPDNGRKHTEGCQAAIYLLQPGANTRVRTWCPTPGPQYGFLVTHNESISIADYFTVRDGQNVVYRPTC
HYAYHPANDAVLSLHEMFGAEGKMQPKWHILDENEIVDGIDELGVLVYGHAKNAYWYGSQLSIEETREICPYQNATGMQV
SSAVLAGMVWALENPEAGIVEADEMDFRRCLEVQKPYLGPVKGYYTDWTPLTDRPGLFPEDIDTSDPWQFKNVLVR
>Mature_475_residues
SSTSKIHAKITGPIVMIGFGSIGKGALPLIERHFEYDKKRFVIIDPHEDGELAKKHGVRFIKQAVTKDNYRELLVPLLTE
GGGQGFCVNLSVDTGSVDLMTMCREIGALYIDTVVEPWLGFYFDKNAGPEKRSNYALRETLLAAKAKNPGGTTAVSTCGA
NPGMVSWFVKQALLDIARDTGLEFNEPKSREGWGQLAQKLGVKGIHIAERDTQRAKTPKPMNVFVNTWSVEGFVSEGLQP
AELGWGTHEKWIPDNGRKHTEGCQAAIYLLQPGANTRVRTWCPTPGPQYGFLVTHNESISIADYFTVRDGQNVVYRPTCH
YAYHPANDAVLSLHEMFGAEGKMQPKWHILDENEIVDGIDELGVLVYGHAKNAYWYGSQLSIEETREICPYQNATGMQVS
SAVLAGMVWALENPEAGIVEADEMDFRRCLEVQKPYLGPVKGYYTDWTPLTDRPGLFPEDIDTSDPWQFKNVLVR

Specific function: Involved in the NAD(+)-dependent synthesis of the polyamine homospermidine from putrescine [H]

COG id: COG5310

COG function: function code Q; Homospermidine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023181
- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: =2.5.1.44 [H]

Molecular weight: Translated: 53017; Mature: 52886

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTSKIHAKITGPIVMIGFGSIGKGALPLIERHFEYDKKRFVIIDPHEDGELAKKHGVR
CCCCCEEEEEEECCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
FIKQAVTKDNYRELLVPLLTEGGGQGFCVNLSVDTGSVDLMTMCREIGALYIDTVVEPWL
HHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
GFYFDKNAGPEKRSNYALRETLLAAKAKNPGGTTAVSTCGANPGMVSWFVKQALLDIARD
HEEECCCCCCCHHCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
TGLEFNEPKSREGWGQLAQKLGVKGIHIAERDTQRAKTPKPMNVFVNTWSVEGFVSEGLQ
CCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCHHHCCCCCCCEEEEEEEEECHHHHCCCC
PAELGWGTHEKWIPDNGRKHTEGCQAAIYLLQPGANTRVRTWCPTPGPQYGFLVTHNESI
HHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCEEEEEEECCCE
SIADYFTVRDGQNVVYRPTCHYAYHPANDAVLSLHEMFGAEGKMQPKWHILDENEIVDGI
EEEEEEEEECCCCEEECCCCCEEECCCCHHHHHHHHHHCCCCCCCCCEEECCCCHHHHCH
DELGVLVYGHAKNAYWYGSQLSIEETREICPYQNATGMQVSSAVLAGMVWALENPEAGIV
HHCCEEEEECCCCCEEECCEECHHHHHHHCCCCCCCCCHHHHHHHHHHHEEECCCCCCCE
EADEMDFRRCLEVQKPYLGPVKGYYTDWTPLTDRPGLFPEDIDTSDPWQFKNVLVR
ECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
SSTSKIHAKITGPIVMIGFGSIGKGALPLIERHFEYDKKRFVIIDPHEDGELAKKHGVR
CCCCEEEEEEECCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
FIKQAVTKDNYRELLVPLLTEGGGQGFCVNLSVDTGSVDLMTMCREIGALYIDTVVEPWL
HHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
GFYFDKNAGPEKRSNYALRETLLAAKAKNPGGTTAVSTCGANPGMVSWFVKQALLDIARD
HEEECCCCCCCHHCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
TGLEFNEPKSREGWGQLAQKLGVKGIHIAERDTQRAKTPKPMNVFVNTWSVEGFVSEGLQ
CCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCHHHCCCCCCCEEEEEEEEECHHHHCCCC
PAELGWGTHEKWIPDNGRKHTEGCQAAIYLLQPGANTRVRTWCPTPGPQYGFLVTHNESI
HHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCEEEEEEECCCE
SIADYFTVRDGQNVVYRPTCHYAYHPANDAVLSLHEMFGAEGKMQPKWHILDENEIVDGI
EEEEEEEEECCCCEEECCCCCEEECCCCHHHHHHHHHHCCCCCCCCCEEECCCCHHHHCH
DELGVLVYGHAKNAYWYGSQLSIEETREICPYQNATGMQVSSAVLAGMVWALENPEAGIV
HHCCEEEEECCCCCEEECCEECHHHHHHHCCCCCCCCCHHHHHHHHHHHEEECCCCCCCE
EADEMDFRRCLEVQKPYLGPVKGYYTDWTPLTDRPGLFPEDIDTSDPWQFKNVLVR
ECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8841401 [H]