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The map label for this gene is lrhA [H]

Identifier: 192289305

GI number: 192289305

Start: 932884

End: 933747

Strand: Reverse

Name: lrhA [H]

Synonym: Rpal_0877

Alternate gene names: 192289305

Gene position: 933747-932884 (Counterclockwise)

Preceding gene: 192289308

Following gene: 192289301

Centisome position: 16.26

GC content: 67.82

Gene sequence:

>864_bases
ATGCTTGATCTCGAACTGCTGCGCAGTTTCGTCTCGGTGGTGGAGGCCGGCGGCTTCACCCTCGCCGGCCAGCGCGTGCA
CCGGACGCAGTCGACGGTCAGTCAGCAGATCAAGCGGCTCGAAGACGATCTCGGCCAGCAGCTACTTGACCGCAGCGGCA
AGGACGTGCTGCCGACCGAGGCGGGCGAGCGGCTACTGTCCTACGCAAGGCGCCTGCTCGCACTCGCCGAAGAGGCGCGC
GACGTGGTGGGGCGGCCGAGCACCGAGGGCGCGGTGCGACTTGGGATTCCAGAAGACTTCGCGCTGTACCGACTGCCGCG
GCTGCTCGGCAATTTCTCGCGCGCCCGTCCCGGCCTGCGACTCGACGTCCGCGCCGATCAAAGCCTGAATTTGAAACGCG
ACCTTGAACGCGGCGATCTCGATCTGGTGCTGCTCAAGCGCGAAGCCGGCGGCACCGGCGCAGTCGCGGCGTGGCCGGAG
CGCGTGTACTGGGTGAACAGCAAGAGCCACCCTTGCAATCCCAAGGCCGGCTCGGTGCCGCTGATCTTCTTTCCCGGCGG
CTGCCTGTATCGACGCCGCGCGATCCACGCGATCGAAGCCGCGGGACGACGCTGGCACATGGCCTATACCAGCTCGAGCC
TGGCCGGAATTCAGGCCGCGGTCGCGGCCGGACTCGGCCTATCGATCCTGTCCGAGATTTCAATTCAGGCCGACCACCGC
AAGCTCACCGCGCGGGACGGCTTCCCGCCGATCGACCGCACCGAGCTCGCGCTGATCGCCGCCCCGCAAGCCAGCCCGGC
AACCCTGCGGCTTGCCGACAGACTCGCCGAGTTTTGCGAGGAGGTCCACACCAAGGCGGCGTGA

Upstream 100 bases:

>100_bases
ATCGAAAGCGTCTCCTGATGCCTAGGACTTAGGGGCCCGCGTTGTCATTGGGAAATTAAATGATAAAATCATCTCCAGTG
GATTTTCGAATGAGGCTGCG

Downstream 100 bases:

>100_bases
GGATTCTTCTCGTCGTCATTCCGGGGCGCGAGCGCAGCTCGCGAACCCGGAATCCCGAGATTCTAGCGCACCAGAGATTC
CGGGTTCGCTCACTGCGTGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MLDLELLRSFVSVVEAGGFTLAGQRVHRTQSTVSQQIKRLEDDLGQQLLDRSGKDVLPTEAGERLLSYARRLLALAEEAR
DVVGRPSTEGAVRLGIPEDFALYRLPRLLGNFSRARPGLRLDVRADQSLNLKRDLERGDLDLVLLKREAGGTGAVAAWPE
RVYWVNSKSHPCNPKAGSVPLIFFPGGCLYRRRAIHAIEAAGRRWHMAYTSSSLAGIQAAVAAGLGLSILSEISIQADHR
KLTARDGFPPIDRTELALIAAPQASPATLRLADRLAEFCEEVHTKAA

Sequences:

>Translated_287_residues
MLDLELLRSFVSVVEAGGFTLAGQRVHRTQSTVSQQIKRLEDDLGQQLLDRSGKDVLPTEAGERLLSYARRLLALAEEAR
DVVGRPSTEGAVRLGIPEDFALYRLPRLLGNFSRARPGLRLDVRADQSLNLKRDLERGDLDLVLLKREAGGTGAVAAWPE
RVYWVNSKSHPCNPKAGSVPLIFFPGGCLYRRRAIHAIEAAGRRWHMAYTSSSLAGIQAAVAAGLGLSILSEISIQADHR
KLTARDGFPPIDRTELALIAAPQASPATLRLADRLAEFCEEVHTKAA
>Mature_287_residues
MLDLELLRSFVSVVEAGGFTLAGQRVHRTQSTVSQQIKRLEDDLGQQLLDRSGKDVLPTEAGERLLSYARRLLALAEEAR
DVVGRPSTEGAVRLGIPEDFALYRLPRLLGNFSRARPGLRLDVRADQSLNLKRDLERGDLDLVLLKREAGGTGAVAAWPE
RVYWVNSKSHPCNPKAGSVPLIFFPGGCLYRRRAIHAIEAAGRRWHMAYTSSSLAGIQAAVAAGLGLSILSEISIQADHR
KLTARDGFPPIDRTELALIAAPQASPATLRLADRLAEFCEEVHTKAA

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=283, Percent_Identity=32.1554770318021, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1787806, Length=234, Percent_Identity=27.7777777777778, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790399, Length=257, Percent_Identity=28.7937743190661, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790208, Length=253, Percent_Identity=27.6679841897233, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788297, Length=242, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI157672245, Length=264, Percent_Identity=25.3787878787879, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI48994962, Length=146, Percent_Identity=32.1917808219178, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI87082132, Length=249, Percent_Identity=26.5060240963855, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787879, Length=248, Percent_Identity=29.4354838709677, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787530, Length=254, Percent_Identity=22.8346456692913, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786713, Length=77, Percent_Identity=44.1558441558442, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI145693105, Length=125, Percent_Identity=30.4, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790262, Length=255, Percent_Identity=25.0980392156863, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787589, Length=128, Percent_Identity=35.15625, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789173, Length=142, Percent_Identity=31.6901408450704, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31373; Mature: 31373

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLELLRSFVSVVEAGGFTLAGQRVHRTQSTVSQQIKRLEDDLGQQLLDRSGKDVLPTE
CCCHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
AGERLLSYARRLLALAEEARDVVGRPSTEGAVRLGIPEDFALYRLPRLLGNFSRARPGLR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCCHHHCCCCCE
LDVRADQSLNLKRDLERGDLDLVLLKREAGGTGAVAAWPERVYWVNSKSHPCNPKAGSVP
EEECCCCCCCHHHHCCCCCEEEEEEEECCCCCCCEEECCCEEEEECCCCCCCCCCCCCEE
LIFFPGGCLYRRRAIHAIEAAGRRWHMAYTSSSLAGIQAAVAAGLGLSILSEISIQADHR
EEEECCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KLTARDGFPPIDRTELALIAAPQASPATLRLADRLAEFCEEVHTKAA
EEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDLELLRSFVSVVEAGGFTLAGQRVHRTQSTVSQQIKRLEDDLGQQLLDRSGKDVLPTE
CCCHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
AGERLLSYARRLLALAEEARDVVGRPSTEGAVRLGIPEDFALYRLPRLLGNFSRARPGLR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCCHHHCCCCCE
LDVRADQSLNLKRDLERGDLDLVLLKREAGGTGAVAAWPERVYWVNSKSHPCNPKAGSVP
EEECCCCCCCHHHHCCCCCEEEEEEEECCCCCCCEEECCCEEEEECCCCCCCCCCCCCEE
LIFFPGGCLYRRRAIHAIEAAGRRWHMAYTSSSLAGIQAAVAAGLGLSILSEISIQADHR
EEEECCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KLTARDGFPPIDRTELALIAAPQASPATLRLADRLAEFCEEVHTKAA
EEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]