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The map label for this gene is dinF [H]

Identifier: 192289296

GI number: 192289296

Start: 920365

End: 921687

Strand: Reverse

Name: dinF [H]

Synonym: Rpal_0868

Alternate gene names: 192289296

Gene position: 921687-920365 (Counterclockwise)

Preceding gene: 192289297

Following gene: 192289295

Centisome position: 16.05

GC content: 67.35

Gene sequence:

>1323_bases
GTGGAATCCGCCCATTCGTCCGTAACCACCCGGCAGGTGTTCGCCATCGCCGGCCCGGCGATGGTCGCGAATCTGACGAC
GCCACTGCTCGGCGTCGTCGCCACTACGGCGATCGGACGGCTCGGCGAGGCGACGCTGCTCGGCGGCGTGTCGATGGCCT
CGGTGCTGTTCGACTGCCTGTTCTGGCTGTTCGGCTTCCTGCGGATGAGCACGCTGGCGTTCACCGCGCAGGCGCTCGGC
GCCGGACAGAGCCGTGAAGTCCCCGCGCACCTGCTGCGCGGACTGATCGTCGCGGCTGGCATCGGCCTGTTGCTGATCGC
GCTGCAAGGTCCGCTCGCCGCGGTGCTGATCGGCGCGATGGGCGGCAGCGAGGCGGTGAGCACCGCCGCCAAGACCTACT
TCTCGATCCGGATCTGGTCGTCGCCGCTGGTGCTGGCGAACTTTGCGGTGCTCGGCTGGCTGGTCGGCCAGGCGCGCGCC
ACACTTGCACTGGCCGTGCAGATCGCCATCAACCTGATCAACATCGCCGCCACCGTGCTGCTGGTGCTGTGGTTCGACTT
CGGCGTCGCCGGCGCCGCGATCGCGGCGGTCATCGCCGAAGGCTCGGGGCTGGTGATCGGGCTCGCGATCGCAGCTTGGC
GCGGCCATGGGCTGTTCAAGGTGTCGCGCGCGATGCTGTTCGATCCGCACCGGTTGCGGCGGATGTTCGCGATCAACCGC
GACATCATGATCCGGACCGCGGCGCTGATCGCCGTATTTCTATTCTTCACCGCGCAGGGCGCGCGCGGCGGCGACGTGGT
GCTCGCCACCAACGCGGTGCTCAACAATTTCCTGATGATCAGCGCGTTCTTCCTCGACGGCCTCGCCAACGCCGCCGAGC
AACTCTGCGGCCGCACCCTCGGGGCTCGCGACCGTGCCGGCTTCGTCAAGGCCACGCGGCTGGTGATCCTGTGGGGCTTC
GGCTTCGCGCTCATCGTCAGCGCGATCTACGCATTCGCCGGGCCGGCGTTGATCGACTTCATCACCTCGAACGAAGAGCT
TCGCCGCACCGCGCGCGATTATCTCTGGCTGGTGACGCTGGCGCCGATGCTCGGCGTGTTCGCGTTCGCCTATGACGGCG
TGTTCATCGGCGCCACCTGGGCTCGCGAGATGCGCAACCTGATGCTGCTGTCGCTGGTGCTGTTCCTGCTGTCGTGGTTC
GCGCTCCGCCCGCTCGGCAACACCGGACTATGGATCGCGCTATTATCTCACTACGTCTGGCGCGGCGGCCTGCAGGCGCT
ACGCTATCCAGCGATGGTGCGGACGTCGTTTTCGGCAAACTGA

Upstream 100 bases:

>100_bases
GCGCTACTTCCTGCTCGGCGCCGTGATCGTGATCCCGATCTGGCTGTTGACGCGGTTGGCCAGCACGCCGCGCGGACGCT
GACGGCAGCCTGCGCCCGCC

Downstream 100 bases:

>100_bases
GTTTTCATCAAATCTCGTTCGCCGAATTAACTCGACATTGATGCCCGTATCACGTGCGGGAAATCGACACTTCGCACATT
CGCCTTCCGCAAATACCATC

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MESAHSSVTTRQVFAIAGPAMVANLTTPLLGVVATTAIGRLGEATLLGGVSMASVLFDCLFWLFGFLRMSTLAFTAQALG
AGQSREVPAHLLRGLIVAAGIGLLLIALQGPLAAVLIGAMGGSEAVSTAAKTYFSIRIWSSPLVLANFAVLGWLVGQARA
TLALAVQIAINLINIAATVLLVLWFDFGVAGAAIAAVIAEGSGLVIGLAIAAWRGHGLFKVSRAMLFDPHRLRRMFAINR
DIMIRTAALIAVFLFFTAQGARGGDVVLATNAVLNNFLMISAFFLDGLANAAEQLCGRTLGARDRAGFVKATRLVILWGF
GFALIVSAIYAFAGPALIDFITSNEELRRTARDYLWLVTLAPMLGVFAFAYDGVFIGATWAREMRNLMLLSLVLFLLSWF
ALRPLGNTGLWIALLSHYVWRGGLQALRYPAMVRTSFSAN

Sequences:

>Translated_440_residues
MESAHSSVTTRQVFAIAGPAMVANLTTPLLGVVATTAIGRLGEATLLGGVSMASVLFDCLFWLFGFLRMSTLAFTAQALG
AGQSREVPAHLLRGLIVAAGIGLLLIALQGPLAAVLIGAMGGSEAVSTAAKTYFSIRIWSSPLVLANFAVLGWLVGQARA
TLALAVQIAINLINIAATVLLVLWFDFGVAGAAIAAVIAEGSGLVIGLAIAAWRGHGLFKVSRAMLFDPHRLRRMFAINR
DIMIRTAALIAVFLFFTAQGARGGDVVLATNAVLNNFLMISAFFLDGLANAAEQLCGRTLGARDRAGFVKATRLVILWGF
GFALIVSAIYAFAGPALIDFITSNEELRRTARDYLWLVTLAPMLGVFAFAYDGVFIGATWAREMRNLMLLSLVLFLLSWF
ALRPLGNTGLWIALLSHYVWRGGLQALRYPAMVRTSFSAN
>Mature_440_residues
MESAHSSVTTRQVFAIAGPAMVANLTTPLLGVVATTAIGRLGEATLLGGVSMASVLFDCLFWLFGFLRMSTLAFTAQALG
AGQSREVPAHLLRGLIVAAGIGLLLIALQGPLAAVLIGAMGGSEAVSTAAKTYFSIRIWSSPLVLANFAVLGWLVGQARA
TLALAVQIAINLINIAATVLLVLWFDFGVAGAAIAAVIAEGSGLVIGLAIAAWRGHGLFKVSRAMLFDPHRLRRMFAINR
DIMIRTAALIAVFLFFTAQGARGGDVVLATNAVLNNFLMISAFFLDGLANAAEQLCGRTLGARDRAGFVKATRLVILWGF
GFALIVSAIYAFAGPALIDFITSNEELRRTARDYLWLVTLAPMLGVFAFAYDGVFIGATWAREMRNLMLLSLVLFLLSWF
ALRPLGNTGLWIALLSHYVWRGGLQALRYPAMVRTSFSAN

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=416, Percent_Identity=38.2211538461538, Blast_Score=189, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 46898; Mature: 46898

Theoretical pI: Translated: 11.19; Mature: 11.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESAHSSVTTRQVFAIAGPAMVANLTTPLLGVVATTAIGRLGEATLLGGVSMASVLFDCL
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FWLFGFLRMSTLAFTAQALGAGQSREVPAHLLRGLIVAAGIGLLLIALQGPLAAVLIGAM
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
GGSEAVSTAAKTYFSIRIWSSPLVLANFAVLGWLVGQARATLALAVQIAINLINIAATVL
CCHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVLWFDFGVAGAAIAAVIAEGSGLVIGLAIAAWRGHGLFKVSRAMLFDPHRLRRMFAINR
HHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCC
DIMIRTAALIAVFLFFTAQGARGGDVVLATNAVLNNFLMISAFFLDGLANAAEQLCGRTL
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GARDRAGFVKATRLVILWGFGFALIVSAIYAFAGPALIDFITSNEELRRTARDYLWLVTL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHH
APMLGVFAFAYDGVFIGATWAREMRNLMLLSLVLFLLSWFALRPLGNTGLWIALLSHYVW
HHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
RGGLQALRYPAMVRTSFSAN
HHHHHHHHCHHHHHCCCCCC
>Mature Secondary Structure
MESAHSSVTTRQVFAIAGPAMVANLTTPLLGVVATTAIGRLGEATLLGGVSMASVLFDCL
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FWLFGFLRMSTLAFTAQALGAGQSREVPAHLLRGLIVAAGIGLLLIALQGPLAAVLIGAM
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
GGSEAVSTAAKTYFSIRIWSSPLVLANFAVLGWLVGQARATLALAVQIAINLINIAATVL
CCHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVLWFDFGVAGAAIAAVIAEGSGLVIGLAIAAWRGHGLFKVSRAMLFDPHRLRRMFAINR
HHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCC
DIMIRTAALIAVFLFFTAQGARGGDVVLATNAVLNNFLMISAFFLDGLANAAEQLCGRTL
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GARDRAGFVKATRLVILWGFGFALIVSAIYAFAGPALIDFITSNEELRRTARDYLWLVTL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHH
APMLGVFAFAYDGVFIGATWAREMRNLMLLSLVLFLLSWFALRPLGNTGLWIALLSHYVW
HHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
RGGLQALRYPAMVRTSFSAN
HHHHHHHHCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]