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The map label for this gene is cobT [H]

Identifier: 192289211

GI number: 192289211

Start: 818772

End: 819827

Strand: Reverse

Name: cobT [H]

Synonym: Rpal_0783

Alternate gene names: 192289211

Gene position: 819827-818772 (Counterclockwise)

Preceding gene: 192289218

Following gene: 192289210

Centisome position: 14.27

GC content: 69.6

Gene sequence:

>1056_bases
ATGCCGACCGACACTCTCGTCACCTGGCAGCCGCCCTCGATCACACCGGTCGACGCGTCGCTGAAAGCAGCTTTGCGAGC
GCGGGTGGACGGCAAGGCCAAGCCGCTCGGCTCGCTCGGGCGGATCGAGGATCTCGCGATCGAGCTCGCTTTGATGCGGC
ATCCGGAGCCGCCGCGCGCCGACAACGCGGTGCTGATGGTGTTCGCTGGCGATCACGGCCTGACCGAAGAAGGCGTCTCG
CAATATCCGTCGGCCGTGACGGTCGCGATGGTGATGACCTATCTGGCCGGCAAGGCCACCGCCAACGCATTCGCGGCAGC
CAACCATGTCGATGTCCGGGTGATCGACGCCGGCGTCGCCGCCGACCTGCCGAAACATCCCGACCTGATCGACGCCAAGG
TGCGGATGGGAACCGGCAATGCGGCGCGCGAGCCGGCGATGAGCGTCGCCGAGGCCGGTCAGGCGCTGAACCGCGGCGCC
GAACTGGCGCGCGCCGAGATCGCGGCAGGGGCCGAGGTGATCGCGCTGGGCGAGATGGGGATCGGCAACACGGCATCCTC
ATCGCTGCTGCTGCACCGGCTCGGCCCGGCGCCGCTCGACCAGAGCATCGGGATTGGCGCCGGTCAGGACGCCGACGGCA
TGGCCAAGAAGAAGGCGGCGATCGAAAAGGCGGCAATCCGCAGCACCGCAACCGCGCCGCTCGAGGTGCTGGCTGAATTC
GGTGGGCTCGAGATCGCCATGATGGCCGGCGCTGTGCTGGGTGCTGCCTCGCAGCGCCGCCCGGTAATCATCGACGGCTT
TATCGCCACCGCCGCGGCGCTGGTCGCGGTGCGACTGGCGCCGGAAGCGCGCGACTATTGCGTGTTCGCCCACCGCTCGG
CCGAACGCGGCCACGATCTCGCGCTGCAGGCGATGGACGCCGCGCCGCTGCTCGATCTCCGGCTGCGGCTCGGCGAAGGA
ACCGGGGCGATCCTCGCAGTGCCTCTGGTGCGCGCCGCCTCGCGGCTGCTCACCGACGTTGCCGATCTCGCCGACGTACT
GGCAGGTAAGCTGTGA

Upstream 100 bases:

>100_bases
TAGCTGCGACGCGGTTGCGGGTCAACAACGCGAAGGTGGTGTTGACCGGGCTTCCGCGTTTGAGTCAGTTGCGCGCCTTG
CCGAACCAAAGGACCGTCCG

Downstream 100 bases:

>100_bases
GTTCGGCGCTGACCAAAGTGGCGGCGATGACCGACCCGGCCGAGATCGCCGCCGCCAACGCCAATCCGCCAGTATTCGAC
GAAGCGTTTAGGGACAAGTT

Product: nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MPTDTLVTWQPPSITPVDASLKAALRARVDGKAKPLGSLGRIEDLAIELALMRHPEPPRADNAVLMVFAGDHGLTEEGVS
QYPSAVTVAMVMTYLAGKATANAFAAANHVDVRVIDAGVAADLPKHPDLIDAKVRMGTGNAAREPAMSVAEAGQALNRGA
ELARAEIAAGAEVIALGEMGIGNTASSSLLLHRLGPAPLDQSIGIGAGQDADGMAKKKAAIEKAAIRSTATAPLEVLAEF
GGLEIAMMAGAVLGAASQRRPVIIDGFIATAAALVAVRLAPEARDYCVFAHRSAERGHDLALQAMDAAPLLDLRLRLGEG
TGAILAVPLVRAASRLLTDVADLADVLAGKL

Sequences:

>Translated_351_residues
MPTDTLVTWQPPSITPVDASLKAALRARVDGKAKPLGSLGRIEDLAIELALMRHPEPPRADNAVLMVFAGDHGLTEEGVS
QYPSAVTVAMVMTYLAGKATANAFAAANHVDVRVIDAGVAADLPKHPDLIDAKVRMGTGNAAREPAMSVAEAGQALNRGA
ELARAEIAAGAEVIALGEMGIGNTASSSLLLHRLGPAPLDQSIGIGAGQDADGMAKKKAAIEKAAIRSTATAPLEVLAEF
GGLEIAMMAGAVLGAASQRRPVIIDGFIATAAALVAVRLAPEARDYCVFAHRSAERGHDLALQAMDAAPLLDLRLRLGEG
TGAILAVPLVRAASRLLTDVADLADVLAGKL
>Mature_350_residues
PTDTLVTWQPPSITPVDASLKAALRARVDGKAKPLGSLGRIEDLAIELALMRHPEPPRADNAVLMVFAGDHGLTEEGVSQ
YPSAVTVAMVMTYLAGKATANAFAAANHVDVRVIDAGVAADLPKHPDLIDAKVRMGTGNAAREPAMSVAEAGQALNRGAE
LARAEIAAGAEVIALGEMGIGNTASSSLLLHRLGPAPLDQSIGIGAGQDADGMAKKKAAIEKAAIRSTATAPLEVLAEFG
GLEIAMMAGAVLGAASQRRPVIIDGFIATAAALVAVRLAPEARDYCVFAHRSAERGHDLALQAMDAAPLLDLRLRLGEGT
GAILAVPLVRAASRLLTDVADLADVLAGKL

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=339, Percent_Identity=33.9233038348083, Blast_Score=172, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 36030; Mature: 35899

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTDTLVTWQPPSITPVDASLKAALRARVDGKAKPLGSLGRIEDLAIELALMRHPEPPRA
CCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
DNAVLMVFAGDHGLTEEGVSQYPSAVTVAMVMTYLAGKATANAFAAANHVDVRVIDAGVA
CCEEEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCHH
ADLPKHPDLIDAKVRMGTGNAAREPAMSVAEAGQALNRGAELARAEIAAGAEVIALGEMG
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
IGNTASSSLLLHRLGPAPLDQSIGIGAGQDADGMAKKKAAIEKAAIRSTATAPLEVLAEF
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GGLEIAMMAGAVLGAASQRRPVIIDGFIATAAALVAVRLAPEARDYCVFAHRSAERGHDL
CCCEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCC
ALQAMDAAPLLDLRLRLGEGTGAILAVPLVRAASRLLTDVADLADVLAGKL
EEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PTDTLVTWQPPSITPVDASLKAALRARVDGKAKPLGSLGRIEDLAIELALMRHPEPPRA
CCCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
DNAVLMVFAGDHGLTEEGVSQYPSAVTVAMVMTYLAGKATANAFAAANHVDVRVIDAGVA
CCEEEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCHH
ADLPKHPDLIDAKVRMGTGNAAREPAMSVAEAGQALNRGAELARAEIAAGAEVIALGEMG
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
IGNTASSSLLLHRLGPAPLDQSIGIGAGQDADGMAKKKAAIEKAAIRSTATAPLEVLAEF
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GGLEIAMMAGAVLGAASQRRPVIIDGFIATAAALVAVRLAPEARDYCVFAHRSAERGHDL
CCCEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCC
ALQAMDAAPLLDLRLRLGEGTGAILAVPLVRAASRLLTDVADLADVLAGKL
EEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA