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The map label for this gene is htxC [H]

Identifier: 192289194

GI number: 192289194

Start: 805375

End: 806241

Strand: Reverse

Name: htxC [H]

Synonym: Rpal_0765

Alternate gene names: 192289194

Gene position: 806241-805375 (Counterclockwise)

Preceding gene: 192289195

Following gene: 192289193

Centisome position: 14.04

GC content: 62.98

Gene sequence:

>867_bases
ATGAGCATCGCCCGCCGCACCTTGAGCTTCGGCGACGAAGCCGGTATCGCTGCCCGCTTTCCCGAACAATTCCGTCCCAA
CTGGATCAAACGCGCCAAGCTGATCGGCGGCCTGATCTTGGCTGCAGCCATCTTCGTATTTGGCCTGATCCGTCTCGAGA
TCCCGTTCGACAGGTTATTCAGCGGCATTGGTCGTCTGATCGAATTTCTCGGCCTGATGCTGCCGCCCGACCCGGGATCA
TGGCAGCTCGCGCAAGTCTATCTTCACGCGATGGGCGAAACGCTGGCGATCGCATTTCTCGGCACACTCGGCGGCGCAGT
GCTGGCGTTTCCCGTGTCGTTCTTGGCTGCCCGCAATGTGCTGCGCATCCGTCCGCTGCAACTCTTGACGCGGCGCCTGC
TCGACGCGGTGCGCGGTATCGACACCCTGATCTGGGCGCTGATCTGGGTCGGCGTCGTCGGCCTCGGTCCGTTCGCCGGC
ATTCTCGCGGTGATGTGCTCGGACTTCGGCAATTTCGGTAAGCTGTTCTCAGAGGCCTTCGAGGCCGCCGACGAAAAGCC
GAGCGAAGGCGTCAAGGCGACCGGCGGCTCGCACGTCCACGGCGTCCGCTTCGGCATGTTGCCACAAGTGGTGCCGATCC
TCGCCAGCCAGGTCCTGTACTTCTTCGAATCCAATACCCGCTCCGCCACCATCATCGGCATCGTCGGTGCCGGCGGCATC
GGCCTGCAGCTCGCCGAGCAGATCCGGGTGCTGGAATGGCAGAAGGTGTCGTTCCTGATCCTGATGATCCTGGTCACCGT
GGCGGCGATCGACTGGATCTCCAGCAAACTGCGCTTCGCGATCATCGGGCGGAAGGCGGTGGGGTAA

Upstream 100 bases:

>100_bases
GCGACGTCAGTGCCATCCTGTTGCTGATCATCGTCACCGTGATGATGATCGACTATTTTACCGAAGGCGTGCGCCGCCGC
CTGATTGGCCAGGAGCGACG

Downstream 100 bases:

>100_bases
CCGCTGGGGCGCGTGCGGATCGATCGCCCGCCCGTTTCTTATGTCGCCCTTATCAGAACGCAGGCGCCGCCCTCTCGATC
CTTTATGCGGATCGGCCGAT

Product: phosphonate ABC transporter inner membrane subunit

Products: 3-phospho-serine [Cytoplasm]; phosphite [Cytoplasm]; ADP; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSIARRTLSFGDEAGIAARFPEQFRPNWIKRAKLIGGLILAAAIFVFGLIRLEIPFDRLFSGIGRLIEFLGLMLPPDPGS
WQLAQVYLHAMGETLAIAFLGTLGGAVLAFPVSFLAARNVLRIRPLQLLTRRLLDAVRGIDTLIWALIWVGVVGLGPFAG
ILAVMCSDFGNFGKLFSEAFEAADEKPSEGVKATGGSHVHGVRFGMLPQVVPILASQVLYFFESNTRSATIIGIVGAGGI
GLQLAEQIRVLEWQKVSFLILMILVTVAAIDWISSKLRFAIIGRKAVG

Sequences:

>Translated_288_residues
MSIARRTLSFGDEAGIAARFPEQFRPNWIKRAKLIGGLILAAAIFVFGLIRLEIPFDRLFSGIGRLIEFLGLMLPPDPGS
WQLAQVYLHAMGETLAIAFLGTLGGAVLAFPVSFLAARNVLRIRPLQLLTRRLLDAVRGIDTLIWALIWVGVVGLGPFAG
ILAVMCSDFGNFGKLFSEAFEAADEKPSEGVKATGGSHVHGVRFGMLPQVVPILASQVLYFFESNTRSATIIGIVGAGGI
GLQLAEQIRVLEWQKVSFLILMILVTVAAIDWISSKLRFAIIGRKAVG
>Mature_287_residues
SIARRTLSFGDEAGIAARFPEQFRPNWIKRAKLIGGLILAAAIFVFGLIRLEIPFDRLFSGIGRLIEFLGLMLPPDPGSW
QLAQVYLHAMGETLAIAFLGTLGGAVLAFPVSFLAARNVLRIRPLQLLTRRLLDAVRGIDTLIWALIWVGVVGLGPFAGI
LAVMCSDFGNFGKLFSEAFEAADEKPSEGVKATGGSHVHGVRFGMLPQVVPILASQVLYFFESNTRSATIIGIVGAGGIG
LQLAEQIRVLEWQKVSFLILMILVTVAAIDWISSKLRFAIIGRKAVG

Specific function: Probably forms part of a binding-protein-dependent hypophosphite transporter [H]

COG id: COG3639

COG function: function code P; ABC-type phosphate/phosphonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR005769 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31172; Mature: 31040

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIARRTLSFGDEAGIAARFPEQFRPNWIKRAKLIGGLILAAAIFVFGLIRLEIPFDRLF
CCCHHHHHCCCCCCCCHHCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SGIGRLIEFLGLMLPPDPGSWQLAQVYLHAMGETLAIAFLGTLGGAVLAFPVSFLAARNV
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRIRPLQLLTRRLLDAVRGIDTLIWALIWVGVVGLGPFAGILAVMCSDFGNFGKLFSEAF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHH
EAADEKPSEGVKATGGSHVHGVRFGMLPQVVPILASQVLYFFESNTRSATIIGIVGAGGI
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCH
GLQLAEQIRVLEWQKVSFLILMILVTVAAIDWISSKLRFAIIGRKAVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCC
>Mature Secondary Structure 
SIARRTLSFGDEAGIAARFPEQFRPNWIKRAKLIGGLILAAAIFVFGLIRLEIPFDRLF
CCHHHHHCCCCCCCCHHCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SGIGRLIEFLGLMLPPDPGSWQLAQVYLHAMGETLAIAFLGTLGGAVLAFPVSFLAARNV
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRIRPLQLLTRRLLDAVRGIDTLIWALIWVGVVGLGPFAGILAVMCSDFGNFGKLFSEAF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHH
EAADEKPSEGVKATGGSHVHGVRFGMLPQVVPILASQVLYFFESNTRSATIIGIVGAGGI
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCH
GLQLAEQIRVLEWQKVSFLILMILVTVAAIDWISSKLRFAIIGRKAVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]