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The map label for this gene is cheW [H]

Identifier: 192288576

GI number: 192288576

Start: 160253

End: 160741

Strand: Reverse

Name: cheW [H]

Synonym: Rpal_0143

Alternate gene names: 192288576

Gene position: 160741-160253 (Counterclockwise)

Preceding gene: 192288577

Following gene: 192288575

Centisome position: 2.8

GC content: 65.64

Gene sequence:

>489_bases
ATGGCCGAAACCGCGCAATATCTGACGCTCGGACTCGCCGGAGAAACGTTCGGAATGGCGATCCGCAACGTTCGCGAAAT
CCTCGATATGCGGCCGATCTCCCGGCTGCCGCACGCGCCGGAGTTCATGCTCGGCATGATCGACGTGCGCGGCACCGGTT
ATCCGATCCTCGATCTTCGGCTGAAGCTCGATCTGCCGGCTGTGCCGCCGACCGAGGCGACCCGCATCATCATTCTCGAC
GTGCCCGTCGCCGGCCGCGTCGTCGGCGTCGGCTTCGTCGCCGACTGTGTCTACGAAGTCACCGACATCGAGGAGAGCTC
GCTGGAGCAGGTCCCCGACGTCGGCGGCAAGTGGAAGTCGGACTACATCGCCGGCATCGGTCGCAAGGGCGATCGCTTCG
TCATCATCTTCGATCTGGCGCGCCTCATGGCCGGCACCGACGTGTCGGCCGGCGCCGCCGAGACCCCATCGAACGACCTG
GCGGCTTGA

Upstream 100 bases:

>100_bases
ATTCGTCGTCGTGCCGAACATGGAACGGATCCTGAATTGAGCGTCCTCGGTCAGACATCCGGCAGTGAATGCCGCCAACC
AGTGTTGAAGTGAGGAAGAC

Downstream 100 bases:

>100_bases
GCCGCCCGGTCGCGATCTGTTGTTGCGTGAGTTTGACCCAAACCTTCGACCCTAAGGAATCTCGAAATGAGACTAACTGT
TAAAGCAAAGCTGGCCGGCG

Product: CheW protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MAETAQYLTLGLAGETFGMAIRNVREILDMRPISRLPHAPEFMLGMIDVRGTGYPILDLRLKLDLPAVPPTEATRIIILD
VPVAGRVVGVGFVADCVYEVTDIEESSLEQVPDVGGKWKSDYIAGIGRKGDRFVIIFDLARLMAGTDVSAGAAETPSNDL
AA

Sequences:

>Translated_162_residues
MAETAQYLTLGLAGETFGMAIRNVREILDMRPISRLPHAPEFMLGMIDVRGTGYPILDLRLKLDLPAVPPTEATRIIILD
VPVAGRVVGVGFVADCVYEVTDIEESSLEQVPDVGGKWKSDYIAGIGRKGDRFVIIFDLARLMAGTDVSAGAAETPSNDL
AA
>Mature_161_residues
AETAQYLTLGLAGETFGMAIRNVREILDMRPISRLPHAPEFMLGMIDVRGTGYPILDLRLKLDLPAVPPTEATRIIILDV
PVAGRVVGVGFVADCVYEVTDIEESSLEQVPDVGGKWKSDYIAGIGRKGDRFVIIFDLARLMAGTDVSAGAAETPSNDLA
A

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=144, Percent_Identity=28.4722222222222, Blast_Score=74, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 17416; Mature: 17285

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETAQYLTLGLAGETFGMAIRNVREILDMRPISRLPHAPEFMLGMIDVRGTGYPILDLR
CCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHCCCCCHHEEEEEEECCCCCEEEEEE
LKLDLPAVPPTEATRIIILDVPVAGRVVGVGFVADCVYEVTDIEESSLEQVPDVGGKWKS
EEECCCCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCC
DYIAGIGRKGDRFVIIFDLARLMAGTDVSAGAAETPSNDLAA
CHHCCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AETAQYLTLGLAGETFGMAIRNVREILDMRPISRLPHAPEFMLGMIDVRGTGYPILDLR
CCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHCCCCCHHEEEEEEECCCCCEEEEEE
LKLDLPAVPPTEATRIIILDVPVAGRVVGVGFVADCVYEVTDIEESSLEQVPDVGGKWKS
EEECCCCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCC
DYIAGIGRKGDRFVIIFDLARLMAGTDVSAGAAETPSNDLAA
CHHCCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]