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The map label for this gene is galU [C]

Identifier: 192288512

GI number: 192288512

Start: 86632

End: 87354

Strand: Reverse

Name: galU [C]

Synonym: Rpal_0079

Alternate gene names: 192288512

Gene position: 87354-86632 (Counterclockwise)

Preceding gene: 192288513

Following gene: 192288511

Centisome position: 1.52

GC content: 67.08

Gene sequence:

>723_bases
ATGACCGTTCGTCCCCACAAAGCCATGGTGCTGGCCGCCGGCCTCGGCCTGCGGATGCGCCCGCTCACCGATCATATGCC
GAAGCCGCTGGTGCGCGTCGCCGGCCGTCCGTTGCTCGACCACGTGCTCGACAGGTTGGCCGAAGTCGACGTCACCGAAG
CCGTCGTCAACGTCCACTATCTGCCGGACCAGATCATCGATCACGTCGCCGGGCGGACCAGCCCGCGGGTGATCATTTCG
GACGAGCGCGATCAGGTGCTCGACACCGGCGGCGCGGTGGTGAAGGCGCTGCCGCTGCTCGGCGATGCGCCGTTCTATCA
TCTCAACGCTGACACGATGTGGATCGACGGCGTGCGGCCGAATCTGGCGCGCCTCGCCGAAGCGTTCGATCCCGCCCGGA
TGGACATCCTGCTGCTGATGGCGCCGACCGCGAACAGCATCGGCTATGCGGGCAAGGGCGACTTTGCGATGAGCCCCGAC
GGCAGCCTGCACAAGCGCAAGGAGACCGAGGTGGTGCCGTTCGTCTATGCGGGCGCCGCCATCATGTCGCCGGCGATTTT
CAAGAACGCGCCGCAGGGCGAGTTCTCGCTGACCAAGATGTTCGATCGCGCCGGCCAGCAGCATCGCCTGCACGGGTTGC
GGCTCGACGGCTTGTGGATGCATGTCGGCACGCCCGACGCGGTGCCTGCAGCCGAACGGGCCTATCTCGCCAGCGTCGCC
TGA

Upstream 100 bases:

>100_bases
GTCATGATCGCCGACTACCCAGTGACCGCCTCCGATAGACCGTTCGGAGCCGCGTGATACAATCGATTCGCGCCGCCCGG
CGCGTTCCGAGTCGGAGAAC

Downstream 100 bases:

>100_bases
GAGGGCGGCCCGCGCCGGCCACCTCCTTTCGCCGGATTTGCCGTGCCATGATGGCGAGGGCGAATCAGGACATCGATGCA
CCTTTTCAGCGTTCCATCTT

Product: nucleotidyl transferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTVRPHKAMVLAAGLGLRMRPLTDHMPKPLVRVAGRPLLDHVLDRLAEVDVTEAVVNVHYLPDQIIDHVAGRTSPRVIIS
DERDQVLDTGGAVVKALPLLGDAPFYHLNADTMWIDGVRPNLARLAEAFDPARMDILLLMAPTANSIGYAGKGDFAMSPD
GSLHKRKETEVVPFVYAGAAIMSPAIFKNAPQGEFSLTKMFDRAGQQHRLHGLRLDGLWMHVGTPDAVPAAERAYLASVA

Sequences:

>Translated_240_residues
MTVRPHKAMVLAAGLGLRMRPLTDHMPKPLVRVAGRPLLDHVLDRLAEVDVTEAVVNVHYLPDQIIDHVAGRTSPRVIIS
DERDQVLDTGGAVVKALPLLGDAPFYHLNADTMWIDGVRPNLARLAEAFDPARMDILLLMAPTANSIGYAGKGDFAMSPD
GSLHKRKETEVVPFVYAGAAIMSPAIFKNAPQGEFSLTKMFDRAGQQHRLHGLRLDGLWMHVGTPDAVPAAERAYLASVA
>Mature_239_residues
TVRPHKAMVLAAGLGLRMRPLTDHMPKPLVRVAGRPLLDHVLDRLAEVDVTEAVVNVHYLPDQIIDHVAGRTSPRVIISD
ERDQVLDTGGAVVKALPLLGDAPFYHLNADTMWIDGVRPNLARLAEAFDPARMDILLLMAPTANSIGYAGKGDFAMSPDG
SLHKRKETEVVPFVYAGAAIMSPAIFKNAPQGEFSLTKMFDRAGQQHRLHGLRLDGLWMHVGTPDAVPAAERAYLASVA

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcN

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Caenorhabditis elegans, GI133931050, Length=228, Percent_Identity=28.5087719298246, Blast_Score=77, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6320148, Length=252, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 26104; Mature: 25972

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRPHKAMVLAAGLGLRMRPLTDHMPKPLVRVAGRPLLDHVLDRLAEVDVTEAVVNVHY
CCCCCCHHEEEEECCCCEECCHHHCCCCHHHHHCCCHHHHHHHHHHHHCCHHHHHHHEEE
LPDQIIDHVAGRTSPRVIISDERDQVLDTGGAVVKALPLLGDAPFYHLNADTMWIDGVRP
CCHHHHHHHHCCCCCEEEEECCCHHHHHCCCHHHHHHHHCCCCCEEEECCCEEEECCCCC
NLARLAEAFDPARMDILLLMAPTANSIGYAGKGDFAMSPDGSLHKRKETEVVPFVYAGAA
HHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHH
IMSPAIFKNAPQGEFSLTKMFDRAGQQHRLHGLRLDGLWMHVGTPDAVPAAERAYLASVA
HHCHHHHCCCCCCCHHHHHHHHHCCCHHHHCEEEECCEEEECCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
TVRPHKAMVLAAGLGLRMRPLTDHMPKPLVRVAGRPLLDHVLDRLAEVDVTEAVVNVHY
CCCCCHHEEEEECCCCEECCHHHCCCCHHHHHCCCHHHHHHHHHHHHCCHHHHHHHEEE
LPDQIIDHVAGRTSPRVIISDERDQVLDTGGAVVKALPLLGDAPFYHLNADTMWIDGVRP
CCHHHHHHHHCCCCCEEEEECCCHHHHHCCCHHHHHHHHCCCCCEEEECCCEEEECCCCC
NLARLAEAFDPARMDILLLMAPTANSIGYAGKGDFAMSPDGSLHKRKETEVVPFVYAGAA
HHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHH
IMSPAIFKNAPQGEFSLTKMFDRAGQQHRLHGLRLDGLWMHVGTPDAVPAAERAYLASVA
HHCHHHHCCCCCCCHHHHHHHHHCCCHHHHCEEEECCEEEECCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA