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The map label for this gene is infC [H]

Identifier: 192288474

GI number: 192288474

Start: 45913

End: 46491

Strand: Reverse

Name: infC [H]

Synonym: Rpal_0041

Alternate gene names: 192288474

Gene position: 46491-45913 (Counterclockwise)

Preceding gene: 192288476

Following gene: 192288473

Centisome position: 0.81

GC content: 57.34

Gene sequence:

>579_bases
TTGTTCGCCGTCAACGTTCACAAGTGTGGAGAAGCACCCATTCGCCGTCCCAACAGAGCGCCGCCCCCCGTAGCCAAGGA
CGGGCCGCGCACCAACGATGAAATCCGCAATTTCGAGATCCAACTGATCGACCAGACCGGTGTGAACCAGGGCAAGGTCG
AGACCATTGTCGCGATCAAAATGGCAATGGATGCAGGCATGGATCTGGTGGAGATTTCGCCGACCTCGTCGCCGCCGGTC
TGTAAGATCATGGACTACGGCAAGTACAAGTATTCGGCGCAGAAGAAGGCCGCCGAGGCGCGCAAAAAACAGAAGATCGT
CGAGATCAAGGAGATCAAACTCCGCCCGATGATCGATGACCACGATTACGAAGTGAAGATGAAGGCGATGCAGCGCTTCT
TCGAGGAAGGCGACAAGGTCAAGATAACCTTGCGCTATCGGGGACGCGAAATGGCTCACCAGGAGATCGGCACCAAGCTG
CTCGAAAAGGTGAAGAACGACGTCGCCGAAATCGCCAAGGTCGAGCAGGATCCCCGCTTCGAAGGCCGTCAGGTCGTGAT
GGTGCTGGCGCCGCGCTGA

Upstream 100 bases:

>100_bases
CATTGACCCTGGTGTCGACGCGCGGGATGGTTTTGCGTCCGGTCGTGCTTCGACCTATATGAAGTGCGGATCCGATCAGC
AGCCGTTCTGACGCGATCCA

Downstream 100 bases:

>100_bases
CGGCGGTCCGGGTTTCGATTTCAGAACGAACAAGGCCCGGCAGCCAATCTGACGGGCCTTTTTCTTTGCGCTTTCTTGGC
CGCTGGGGTCGCCCGTCGTC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MFAVNVHKCGEAPIRRPNRAPPPVAKDGPRTNDEIRNFEIQLIDQTGVNQGKVETIVAIKMAMDAGMDLVEISPTSSPPV
CKIMDYGKYKYSAQKKAAEARKKQKIVEIKEIKLRPMIDDHDYEVKMKAMQRFFEEGDKVKITLRYRGREMAHQEIGTKL
LEKVKNDVAEIAKVEQDPRFEGRQVVMVLAPR

Sequences:

>Translated_192_residues
MFAVNVHKCGEAPIRRPNRAPPPVAKDGPRTNDEIRNFEIQLIDQTGVNQGKVETIVAIKMAMDAGMDLVEISPTSSPPV
CKIMDYGKYKYSAQKKAAEARKKQKIVEIKEIKLRPMIDDHDYEVKMKAMQRFFEEGDKVKITLRYRGREMAHQEIGTKL
LEKVKNDVAEIAKVEQDPRFEGRQVVMVLAPR
>Mature_192_residues
MFAVNVHKCGEAPIRRPNRAPPPVAKDGPRTNDEIRNFEIQLIDQTGVNQGKVETIVAIKMAMDAGMDLVEISPTSSPPV
CKIMDYGKYKYSAQKKAAEARKKQKIVEIKEIKLRPMIDDHDYEVKMKAMQRFFEEGDKVKITLRYRGREMAHQEIGTKL
LEKVKNDVAEIAKVEQDPRFEGRQVVMVLAPR

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=54.2682926829268, Blast_Score=169, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 21923; Mature: 21923

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAVNVHKCGEAPIRRPNRAPPPVAKDGPRTNDEIRNFEIQLIDQTGVNQGKVETIVAIK
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCEEEEEEECCCCCCCCHHHHHHHH
MAMDAGMDLVEISPTSSPPVCKIMDYGKYKYSAQKKAAEARKKQKIVEIKEIKLRPMIDD
HHHHCCCCEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
HDYEVKMKAMQRFFEEGDKVKITLRYRGREMAHQEIGTKLLEKVKNDVAEIAKVEQDPRF
CCCEEHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EGRQVVMVLAPR
CCCEEEEEEECC
>Mature Secondary Structure
MFAVNVHKCGEAPIRRPNRAPPPVAKDGPRTNDEIRNFEIQLIDQTGVNQGKVETIVAIK
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCEEEEEEECCCCCCCCHHHHHHHH
MAMDAGMDLVEISPTSSPPVCKIMDYGKYKYSAQKKAAEARKKQKIVEIKEIKLRPMIDD
HHHHCCCCEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
HDYEVKMKAMQRFFEEGDKVKITLRYRGREMAHQEIGTKLLEKVKNDVAEIAKVEQDPRF
CCCEEHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EGRQVVMVLAPR
CCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]