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The map label for this gene is xylB [H]

Identifier: 190895247

GI number: 190895247

Start: 1008221

End: 1009327

Strand: Reverse

Name: xylB [H]

Synonym: RHECIAT_PC0000920

Alternate gene names: 190895247

Gene position: 1009327-1008221 (Counterclockwise)

Preceding gene: 190895248

Following gene: 190895246

Centisome position: 92.47

GC content: 65.22

Gene sequence:

>1107_bases
ATGAAGATTCACGCCGCGGTGGCGCGTGCGCCGCATATGCCGCTTTCACTAGAAAGCCTCGATTTGGAGGAGCCGCGCGA
GGGCGAGATCCTGGTCCGCGTCGTGGCAACGGGAGTTTGCCATACCGACATCGTCATGCGCGATCAGCACCTGCCGGTGC
CGCAGCCGGTCGTGCTCGGCCATGAAGGCGCCGGCATCGTCGAACGCGTCGGGCCCGGCGTCAGCAAGGTGGCGCCCGGC
GATCACGTGGTCATGACCTTCAATTCCTGCGGTCATTGCCCGAGCTGCAACGATCACGAGGAGACCTACTGCCACGAATT
CTTTCCGCGCAATTTCTTCGGTTCGCGGGCGGATGGTTCGAGCGGGCTTTCCTATCGGGGGGAGCGGGTGCACGGCAATA
TTTTCGGGCAGTCCTCCTTTGCAAGCCATGCGCTCTGCCATGAGCGCAACATCGTCAAAGTACCTGATGACGCCGATCTG
GCGCTGCTCGGTCCGCTCGCCTGCGGCATCCAGACCGGCGCCGGCGCGGTCATGAATGCATTGAAGGTCGAGCCGGGAAA
AGTGCTTGCGGTGTTCGGCCTGGGCTCGGTTGGCCTTGCCGCCGTCATGGCGGCGCGGGTCGTCGGCGCTTCCAGGATCA
TCGCGGTCGACGTCAATGTGGCGCGGCTGGCACTTGCGGCTGAGCTCGGCGCGACCGATATTGTCGACGGCAAGACCGGC
GATGCGGTCGCCGCGATCATGGCGCTGACCGGCGCCGGCGTCGATTATGCGATCGATGCCTCCGGCGTGCCCGCCGTCAT
CGACCAATGCGTGCGGGTGCTCGCGCCGCGCGGCACCTGCGGCATCGTCGGGGCTTCGCCGCACGGCGCGACGCTGACGC
TCGACCTCACCCATATTCTCTCCGGCGGACGCCGGGTGCGCGGCATCGTCGAGGGCGACTCCAATCCCGATGTGCTGATC
CCGCTTTTGATCGACCTTCACAGACAGGGCCGCTTTCCCTTCGACAGGCTGGTCACCTTCTATGATTTCGCCGACATCAA
CCAGGCGGTGGAGGATGCGCAAAGGGGCATAGTGCTGAAACCGGTCGTGCGTCAGCCGGCCGCCTGA

Upstream 100 bases:

>100_bases
CAAGACCTATCAGCCGGGACTCGGCGCTTACAAGCGCGGCCGTTGAGGTCAGGCCTGGCATGGCCGGGCCGTGACGGATT
GCTATCGGGAGGAGGAAGCA

Downstream 100 bases:

>100_bases
GACAGTTCAAGGGAGGAAAGAATGAACATCGTCAGCCCAATCACCGTCGATACCAGCCCCGACGCCATGAAGGCGCTGCT
TGCCCAGCAAAGGGCGTCTT

Product: putative aryl-alcohol dehydrogenase

Products: NA

Alternate protein names: Benzyl alcohol dehydrogenase; BADH [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKIHAAVARAPHMPLSLESLDLEEPREGEILVRVVATGVCHTDIVMRDQHLPVPQPVVLGHEGAGIVERVGPGVSKVAPG
DHVVMTFNSCGHCPSCNDHEETYCHEFFPRNFFGSRADGSSGLSYRGERVHGNIFGQSSFASHALCHERNIVKVPDDADL
ALLGPLACGIQTGAGAVMNALKVEPGKVLAVFGLGSVGLAAVMAARVVGASRIIAVDVNVARLALAAELGATDIVDGKTG
DAVAAIMALTGAGVDYAIDASGVPAVIDQCVRVLAPRGTCGIVGASPHGATLTLDLTHILSGGRRVRGIVEGDSNPDVLI
PLLIDLHRQGRFPFDRLVTFYDFADINQAVEDAQRGIVLKPVVRQPAA

Sequences:

>Translated_368_residues
MKIHAAVARAPHMPLSLESLDLEEPREGEILVRVVATGVCHTDIVMRDQHLPVPQPVVLGHEGAGIVERVGPGVSKVAPG
DHVVMTFNSCGHCPSCNDHEETYCHEFFPRNFFGSRADGSSGLSYRGERVHGNIFGQSSFASHALCHERNIVKVPDDADL
ALLGPLACGIQTGAGAVMNALKVEPGKVLAVFGLGSVGLAAVMAARVVGASRIIAVDVNVARLALAAELGATDIVDGKTG
DAVAAIMALTGAGVDYAIDASGVPAVIDQCVRVLAPRGTCGIVGASPHGATLTLDLTHILSGGRRVRGIVEGDSNPDVLI
PLLIDLHRQGRFPFDRLVTFYDFADINQAVEDAQRGIVLKPVVRQPAA
>Mature_368_residues
MKIHAAVARAPHMPLSLESLDLEEPREGEILVRVVATGVCHTDIVMRDQHLPVPQPVVLGHEGAGIVERVGPGVSKVAPG
DHVVMTFNSCGHCPSCNDHEETYCHEFFPRNFFGSRADGSSGLSYRGERVHGNIFGQSSFASHALCHERNIVKVPDDADL
ALLGPLACGIQTGAGAVMNALKVEPGKVLAVFGLGSVGLAAVMAARVVGASRIIAVDVNVARLALAAELGATDIVDGKTG
DAVAAIMALTGAGVDYAIDASGVPAVIDQCVRVLAPRGTCGIVGASPHGATLTLDLTHILSGGRRVRGIVEGDSNPDVLI
PLLIDLHRQGRFPFDRLVTFYDFADINQAVEDAQRGIVLKPVVRQPAA

Specific function: Oxidizes primary alcohols with an aromatic or cyclohex- 1-ene ring. It is highly specific for benzyl alcohol [H]

COG id: COG1062

COG function: function code C; Zn-dependent alcohol dehydrogenases, class III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156523966, Length=374, Percent_Identity=33.9572192513369, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI34577061, Length=368, Percent_Identity=34.5108695652174, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI4501939, Length=367, Percent_Identity=34.6049046321526, Blast_Score=201, Evalue=7e-52,
Organism=Homo sapiens, GI71565152, Length=373, Percent_Identity=33.2439678284182, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI4501929, Length=368, Percent_Identity=32.6086956521739, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI4501933, Length=368, Percent_Identity=32.6086956521739, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI71565154, Length=373, Percent_Identity=33.5120643431635, Blast_Score=188, Evalue=9e-48,
Organism=Homo sapiens, GI262073058, Length=370, Percent_Identity=31.3513513513514, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI71743840, Length=370, Percent_Identity=31.3513513513514, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI156627571, Length=373, Percent_Identity=23.8605898123324, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1786552, Length=371, Percent_Identity=33.6927223719677, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1788073, Length=365, Percent_Identity=29.3150684931507, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI87081918, Length=249, Percent_Identity=32.9317269076305, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788407, Length=272, Percent_Identity=26.4705882352941, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082125, Length=276, Percent_Identity=28.2608695652174, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786518, Length=304, Percent_Identity=28.6184210526316, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790045, Length=289, Percent_Identity=26.643598615917, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790718, Length=333, Percent_Identity=25.2252252252252, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788075, Length=291, Percent_Identity=28.1786941580756, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787863, Length=343, Percent_Identity=24.198250728863, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI25146526, Length=377, Percent_Identity=33.42175066313, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI71997431, Length=379, Percent_Identity=33.245382585752, Blast_Score=181, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17565904, Length=340, Percent_Identity=32.9411764705882, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17562876, Length=367, Percent_Identity=27.2479564032698, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17562584, Length=348, Percent_Identity=25.8620689655172, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562582, Length=308, Percent_Identity=26.9480519480519, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71988145, Length=346, Percent_Identity=23.6994219653179, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562878, Length=271, Percent_Identity=27.6752767527675, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320033, Length=374, Percent_Identity=31.0160427807487, Blast_Score=172, Evalue=9e-44,
Organism=Saccharomyces cerevisiae, GI6324486, Length=291, Percent_Identity=29.2096219931272, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319621, Length=283, Percent_Identity=28.6219081272085, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323729, Length=296, Percent_Identity=29.0540540540541, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6323961, Length=288, Percent_Identity=29.1666666666667, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319258, Length=277, Percent_Identity=26.3537906137184, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6319257, Length=275, Percent_Identity=26.1818181818182, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17737895, Length=369, Percent_Identity=30.6233062330623, Blast_Score=172, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.90 [H]

Molecular weight: Translated: 38515; Mature: 38515

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHAAVARAPHMPLSLESLDLEEPREGEILVRVVATGVCHTDIVMRDQHLPVPQPVVLG
CCCCHHHHCCCCCCCEECCCCCCCCCCCCEEEEEECCCCCHHHEEEECCCCCCCCCEEEC
HEGAGIVERVGPGVSKVAPGDHVVMTFNSCGHCPSCNDHEETYCHEFFPRNFFGSRADGS
CCCCCHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
SGLSYRGERVHGNIFGQSSFASHALCHERNIVKVPDDADLALLGPLACGIQTGAGAVMNA
CCCCCCCCEEEEEEECCCCHHHHHHHHCCCEEECCCCCCEEEECHHHHCCCCCCHHHHHH
LKVEPGKVLAVFGLGSVGLAAVMAARVVGASRIIAVDVNVARLALAAELGATDIVDGKTG
HCCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEECCCCCC
DAVAAIMALTGAGVDYAIDASGVPAVIDQCVRVLAPRGTCGIVGASPHGATLTLDLTHIL
HHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEHHHHH
SGGRRVRGIVEGDSNPDVLIPLLIDLHRQGRFPFDRLVTFYDFADINQAVEDAQRGIVLK
CCCCEEEEEEECCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEE
PVVRQPAA
HHHCCCCC
>Mature Secondary Structure
MKIHAAVARAPHMPLSLESLDLEEPREGEILVRVVATGVCHTDIVMRDQHLPVPQPVVLG
CCCCHHHHCCCCCCCEECCCCCCCCCCCCEEEEEECCCCCHHHEEEECCCCCCCCCEEEC
HEGAGIVERVGPGVSKVAPGDHVVMTFNSCGHCPSCNDHEETYCHEFFPRNFFGSRADGS
CCCCCHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
SGLSYRGERVHGNIFGQSSFASHALCHERNIVKVPDDADLALLGPLACGIQTGAGAVMNA
CCCCCCCCEEEEEEECCCCHHHHHHHHCCCEEECCCCCCEEEECHHHHCCCCCCHHHHHH
LKVEPGKVLAVFGLGSVGLAAVMAARVVGASRIIAVDVNVARLALAAELGATDIVDGKTG
HCCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEECCCCCC
DAVAAIMALTGAGVDYAIDASGVPAVIDQCVRVLAPRGTCGIVGASPHGATLTLDLTHIL
HHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEHHHHH
SGGRRVRGIVEGDSNPDVLIPLLIDLHRQGRFPFDRLVTFYDFADINQAVEDAQRGIVLK
CCCCEEEEEEECCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEE
PVVRQPAA
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8496150; 1989592 [H]