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The map label for this gene is kch [H]

Identifier: 190894692

GI number: 190894692

Start: 381171

End: 382226

Strand: Reverse

Name: kch [H]

Synonym: RHECIAT_PC0000355

Alternate gene names: 190894692

Gene position: 382226-381171 (Counterclockwise)

Preceding gene: 190894696

Following gene: 190894691

Centisome position: 35.02

GC content: 59.28

Gene sequence:

>1056_bases
TTGCCATTTATCGCTTCATTTCTGCGGCGTATATATCTTTCGCTGGGCGAGTTGGCCTGGTCAGCGCTTTTTCTTATCCT
CGTTCTTCATCTGGTCTTGTCTTACCTGCTCTTTATGCTGGCAGGCGAGGGCGATCTCGTCGGCAGGCCGGTCGACTTCG
TTTATTATTATATGGTCACCGCAACGACTGTCGGCTATGGCGATCTTTCTCCAAAGTCGGCGCCCGGCCGGCTCATCACC
GTGCTGATCGTTCTTCCCGGTGGCATTGCCATCTTTACTGCAGTTCTTGGCAAGTTGTTGACAGCTATCGGTACGATTTG
GAGGAATCGCATGCGCGGATTGGGTGATTACAGCGAACGCGCCGGCCATATTATCGTTGTAGGCTGGCAAGAGGGGCAGA
CACACCAGACACTGCGGCTGCTGCATTCCGAACGCCATGCCAACGAGCCGATGAGCGTTCTGGTCGCCAAGGACCTGCCG
GAAAATCCTGCCACCGACTACGCCGACTATATCAGAAGCGATCGGCTTGCCGATGCCGACGCCTTGACTCGGGCCGGCAT
AGCCCAGGCGCGCGCGATCATTGCGCGCGGCGCCAATGACGACGAAACGCTGGCCGCAGTCCTGATTGCCGAGGATCACG
CGCCCAATGCCCATATCGTTGCTTATTTCGACGATGACCGCACGGCGCAGATGGTCAAACAGCTGCGGCCGCGCGTCGAG
GCGGTGGGATCGCTCGCCGAGGAGCTCCTGTCGCGTTCAGCGCGTGATCCCGGCTCCTCGGAAATCGCCGCACGGCTGCT
GTCGGCCGCCTCCACCGACACGGCCTTTTCCCTGCCGGTGCCGCCTTTGCAAACGCCACTGCTCTATGGCGAGGTATTTT
TAAGGCTCAAGCGCCGGTACAACGTGACACTGGTGGGCATGCTGAGCGAGGGCATGACCGATCTGAATTGCCGAGACGAG
ACGCCGATGCGCGGCGGCGAGACTCTTTACTACATCAGCGGAATGCGGCTAGATCCCGCCGCCATCGCCTGGGCTAGAAT
GGGAGACGAAACATGA

Upstream 100 bases:

>100_bases
TTAGAGCGTCAAAAATATCTGGGTAGTCGGTTTACAACTTAAAGGTCTGGCGCGCGAAATAAATTTCGATAGGGTGCACG
TTAGCAACCGGGGGAATCGC

Downstream 100 bases:

>100_bases
TCGGCTGGTTCGGTGGAAACAAGGACGAAAAGCCCCTGCCAAAAGAACTCGGTCCCTTGAGCGTGGCCATCGGTGGGGCG
TTCGAGATCGATTTCCTCTC

Product: putative cation transporter (potassium channel) protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MPFIASFLRRIYLSLGELAWSALFLILVLHLVLSYLLFMLAGEGDLVGRPVDFVYYYMVTATTVGYGDLSPKSAPGRLIT
VLIVLPGGIAIFTAVLGKLLTAIGTIWRNRMRGLGDYSERAGHIIVVGWQEGQTHQTLRLLHSERHANEPMSVLVAKDLP
ENPATDYADYIRSDRLADADALTRAGIAQARAIIARGANDDETLAAVLIAEDHAPNAHIVAYFDDDRTAQMVKQLRPRVE
AVGSLAEELLSRSARDPGSSEIAARLLSAASTDTAFSLPVPPLQTPLLYGEVFLRLKRRYNVTLVGMLSEGMTDLNCRDE
TPMRGGETLYYISGMRLDPAAIAWARMGDET

Sequences:

>Translated_351_residues
MPFIASFLRRIYLSLGELAWSALFLILVLHLVLSYLLFMLAGEGDLVGRPVDFVYYYMVTATTVGYGDLSPKSAPGRLIT
VLIVLPGGIAIFTAVLGKLLTAIGTIWRNRMRGLGDYSERAGHIIVVGWQEGQTHQTLRLLHSERHANEPMSVLVAKDLP
ENPATDYADYIRSDRLADADALTRAGIAQARAIIARGANDDETLAAVLIAEDHAPNAHIVAYFDDDRTAQMVKQLRPRVE
AVGSLAEELLSRSARDPGSSEIAARLLSAASTDTAFSLPVPPLQTPLLYGEVFLRLKRRYNVTLVGMLSEGMTDLNCRDE
TPMRGGETLYYISGMRLDPAAIAWARMGDET
>Mature_350_residues
PFIASFLRRIYLSLGELAWSALFLILVLHLVLSYLLFMLAGEGDLVGRPVDFVYYYMVTATTVGYGDLSPKSAPGRLITV
LIVLPGGIAIFTAVLGKLLTAIGTIWRNRMRGLGDYSERAGHIIVVGWQEGQTHQTLRLLHSERHANEPMSVLVAKDLPE
NPATDYADYIRSDRLADADALTRAGIAQARAIIARGANDDETLAAVLIAEDHAPNAHIVAYFDDDRTAQMVKQLRPRVEA
VGSLAEELLSRSARDPGSSEIAARLLSAASTDTAFSLPVPPLQTPLLYGEVFLRLKRRYNVTLVGMLSEGMTDLNCRDET
PMRGGETLYYISGMRLDPAAIAWARMGDET

Specific function: May play a role in the defense against osmotic shock [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787503, Length=196, Percent_Identity=30.1020408163265, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF07885 Ion_trans_2; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 38461; Mature: 38330

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFIASFLRRIYLSLGELAWSALFLILVLHLVLSYLLFMLAGEGDLVGRPVDFVYYYMVT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
ATTVGYGDLSPKSAPGRLITVLIVLPGGIAIFTAVLGKLLTAIGTIWRNRMRGLGDYSER
HHHCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHC
AGHIIVVGWQEGQTHQTLRLLHSERHANEPMSVLVAKDLPENPATDYADYIRSDRLADAD
CCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCHH
ALTRAGIAQARAIIARGANDDETLAAVLIAEDHAPNAHIVAYFDDDRTAQMVKQLRPRVE
HHHHHHHHHHHHHHHCCCCCCHHEEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHH
AVGSLAEELLSRSARDPGSSEIAARLLSAASTDTAFSLPVPPLQTPLLYGEVFLRLKRRY
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHC
NVTLVGMLSEGMTDLNCRDETPMRGGETLYYISGMRLDPAAIAWARMGDET
CEEEEEEHHCCCCCCCCCCCCCCCCCCEEEEEECCEECHHHHHHHHCCCCC
>Mature Secondary Structure 
PFIASFLRRIYLSLGELAWSALFLILVLHLVLSYLLFMLAGEGDLVGRPVDFVYYYMVT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
ATTVGYGDLSPKSAPGRLITVLIVLPGGIAIFTAVLGKLLTAIGTIWRNRMRGLGDYSER
HHHCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHC
AGHIIVVGWQEGQTHQTLRLLHSERHANEPMSVLVAKDLPENPATDYADYIRSDRLADAD
CCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCHH
ALTRAGIAQARAIIARGANDDETLAAVLIAEDHAPNAHIVAYFDDDRTAQMVKQLRPRVE
HHHHHHHHHHHHHHHCCCCCCHHEEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHH
AVGSLAEELLSRSARDPGSSEIAARLLSAASTDTAFSLPVPPLQTPLLYGEVFLRLKRRY
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHC
NVTLVGMLSEGMTDLNCRDETPMRGGETLYYISGMRLDPAAIAWARMGDET
CEEEEEEHHCCCCCCCCCCCCCCCCCCEEEEEECCEECHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8170937; 9097039; 9278503 [H]