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The map label for this gene is appC [H]

Identifier: 190894655

GI number: 190894655

Start: 341210

End: 342169

Strand: Reverse

Name: appC [H]

Synonym: RHECIAT_PC0000318

Alternate gene names: 190894655

Gene position: 342169-341210 (Counterclockwise)

Preceding gene: 190894656

Following gene: 190894654

Centisome position: 31.35

GC content: 63.75

Gene sequence:

>960_bases
ATGTCCGCAATCCCTCTTTCCACCCCCGAAACCATCGAGGAGCCGCCGGTCAGCCTGTGGCGCGACGCCTGGCATCGGCT
GCGGCGCAACAAGCTCGCCGTCTTCGGCCTCGTCGTCGTCCTGATCCTCGCCTTCACCGCGATCTTCGGGCCTTACCTCA
CGCCCTATGATTATCTCAGTCAGGACCTCAACGCCCGCAACGCGCTGCCGTCGATGAGCCACCTCTTCGGAACCGACGAC
CTCGGCCGCGATGTCTTCAGCCGCGTCGTGTTCGGCACGCGCACCGCCTTCCTCGTTGCCGTCATCGTCACCTTCTTCGC
CGTGCTGATCGGCCTCACACTCGGCGCCGTCGCCGGTTTCTTCGGCAATCCTTTCGACCGGGCCATCATGTGGCTGACCG
ACGTCACGATGTCGGTGCCAAACCTGCTGCTCGTCGTCGTCATCAATGCCTCGCTGAAATCGCCGATCACCCGATGGATG
GAAGCGCGCTACCTCGAGACCCTCAATCCCTTCTACCGCCAGACGATCTGGGTGGATTTCATCCTCGTTTTCGGGTCGAT
GGCGCTGATCTCCTGGCCGCCCTATGCCCGTCTGGTGCGCGCCCAGGTTCTGTCGATCCGCAGCCGGCCTTATATCACCG
CTGCCCAGGCGCTCGGGCTTTCGAACTGGGTCATCATCAAGCGCTATGTCGTTCCGAATGCACTTGGCCCGCTCATCGTC
TCGGTCAGCGCCGGTCTCGGCACTGCGATGGTGCTGGAAAGCGCCTTCAGCTTCCTCGGGGTCGGGGTCAACCCGCCGAC
GCCGAGCTGGGGCAACATGATCTCGGACGGCCTTCGCGTCTGGCAGCATTATCCGCATCTTCTCGCCGCTCCGGCGGCCG
TGCTCGGCCTTGCATCGGTTGCCTTCAGCTTCCTCGGCGACGGCCTCAACGACGCGCTCAATCCGCGGGGCAGCAAATGA

Upstream 100 bases:

>100_bases
TGATCGGATCGTTCCTGGTGATGGTGTCGAACCTCCTGGTGGACGTGCTCTATCCGCTGCTCGATCCGCGCGCCAACGAT
TCAAGAAGGAGCCGCTGACC

Downstream 100 bases:

>100_bases
TGGACACGCAAAACAGAGAACGCCTGCTCGACGTCAGGGGCCTCACCGTCGAGATCGACGGCCGCAACGGCCCGGCCGTC
GTCGTCGACGGCATCGATCT

Product: putative oligopeptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSAIPLSTPETIEEPPVSLWRDAWHRLRRNKLAVFGLVVVLILAFTAIFGPYLTPYDYLSQDLNARNALPSMSHLFGTDD
LGRDVFSRVVFGTRTAFLVAVIVTFFAVLIGLTLGAVAGFFGNPFDRAIMWLTDVTMSVPNLLLVVVINASLKSPITRWM
EARYLETLNPFYRQTIWVDFILVFGSMALISWPPYARLVRAQVLSIRSRPYITAAQALGLSNWVIIKRYVVPNALGPLIV
SVSAGLGTAMVLESAFSFLGVGVNPPTPSWGNMISDGLRVWQHYPHLLAAPAAVLGLASVAFSFLGDGLNDALNPRGSK

Sequences:

>Translated_319_residues
MSAIPLSTPETIEEPPVSLWRDAWHRLRRNKLAVFGLVVVLILAFTAIFGPYLTPYDYLSQDLNARNALPSMSHLFGTDD
LGRDVFSRVVFGTRTAFLVAVIVTFFAVLIGLTLGAVAGFFGNPFDRAIMWLTDVTMSVPNLLLVVVINASLKSPITRWM
EARYLETLNPFYRQTIWVDFILVFGSMALISWPPYARLVRAQVLSIRSRPYITAAQALGLSNWVIIKRYVVPNALGPLIV
SVSAGLGTAMVLESAFSFLGVGVNPPTPSWGNMISDGLRVWQHYPHLLAAPAAVLGLASVAFSFLGDGLNDALNPRGSK
>Mature_318_residues
SAIPLSTPETIEEPPVSLWRDAWHRLRRNKLAVFGLVVVLILAFTAIFGPYLTPYDYLSQDLNARNALPSMSHLFGTDDL
GRDVFSRVVFGTRTAFLVAVIVTFFAVLIGLTLGAVAGFFGNPFDRAIMWLTDVTMSVPNLLLVVVINASLKSPITRWME
ARYLETLNPFYRQTIWVDFILVFGSMALISWPPYARLVRAQVLSIRSRPYITAAQALGLSNWVIIKRYVVPNALGPLIVS
VSAGLGTAMVLESAFSFLGVGVNPPTPSWGNMISDGLRVWQHYPHLLAAPAAVLGLASVAFSFLGDGLNDALNPRGSK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=317, Percent_Identity=32.807570977918, Blast_Score=187, Evalue=7e-49,
Organism=Escherichia coli, GI1787760, Length=290, Percent_Identity=32.4137931034483, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1787498, Length=309, Percent_Identity=34.6278317152104, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1789964, Length=314, Percent_Identity=36.3057324840764, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1789889, Length=262, Percent_Identity=29.7709923664122, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787549, Length=316, Percent_Identity=27.8481012658228, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788505, Length=246, Percent_Identity=28.8617886178862, Blast_Score=91, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34966; Mature: 34835

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIPLSTPETIEEPPVSLWRDAWHRLRRNKLAVFGLVVVLILAFTAIFGPYLTPYDYLS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
QDLNARNALPSMSHLFGTDDLGRDVFSRVVFGTRTAFLVAVIVTFFAVLIGLTLGAVAGF
HHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGNPFDRAIMWLTDVTMSVPNLLLVVVINASLKSPITRWMEARYLETLNPFYRQTIWVDF
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILVFGSMALISWPPYARLVRAQVLSIRSRPYITAAQALGLSNWVIIKRYVVPNALGPLIV
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHCCCCHHHHHH
SVSAGLGTAMVLESAFSFLGVGVNPPTPSWGNMISDGLRVWQHYPHLLAAPAAVLGLASV
HHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFSFLGDGLNDALNPRGSK
HHHHHCCCHHHHCCCCCCC
>Mature Secondary Structure 
SAIPLSTPETIEEPPVSLWRDAWHRLRRNKLAVFGLVVVLILAFTAIFGPYLTPYDYLS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH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HHHHHCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]