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The map label for this gene is pipc1 [H]

Identifier: 190894574

GI number: 190894574

Start: 236312

End: 237202

Strand: Reverse

Name: pipc1 [H]

Synonym: RHECIAT_PC0000236

Alternate gene names: 190894574

Gene position: 237202-236312 (Counterclockwise)

Preceding gene: 190894577

Following gene: 190894573

Centisome position: 21.73

GC content: 60.83

Gene sequence:

>891_bases
ATGTGGCGTGAAATACAGCCGGACGAGCGATTCGAGATCGATGTCGATGGCTATCGCGTCGTTGCCTACAGTTTCGGGAC
CGGCAGCGAGACGATTTTCTGCCTGAACGGCGGGCCGGGTCTGCCCTGCGATTATCTGCGCGAGGCGCATTCCTGTCTCG
TCGAAAAAGGTTATCGTGTTATCGCTTTCGACCAGCTCGGCACCGGCGCTTCCGACCGGCCGGACGATCCCTCGCTCTGG
ACGATCGGCCGTTATGTCGAAGAGACGGAAACGGTGCGCAAGGCGCTGGCGCTCGGCAAAGTCCACATGCTCGGCCATTC
CTGGGGCGGGTGGCTGGCGATCGAATATGCGCTGACTTACGCTCAGAACCTCAAGACCCTGATTCTCGAGGATACCGTCG
CCGACATGCCGCATCTGATCTCGGAACTGGAGCGGCTGCGCGCGGCACTCGGTCCCGAAACCGTCTCGATGATGCAGAAG
CACGAGGCGCAAGGCACCTATAATCATCCCGAATATCTCGCCGCCGTCACCATCCTCAACTACCGCCATGTCTGCCGTCT
TCAGGAATGGCCGGCGCCGGTCCGCCGCTCGCTCGACGACTGGAATATGGCGCCCTATGAGACGATGCAGGGGCCGAACG
AGTTTCTCTATATCGGCAACCTCAAGGACTGGAACCGCATTGCCGATCTGCCGCGGCTGACGCTGCCGGTGCTGATCACC
GCGGGAGAGCATGACGAGCTGACACCGGCCTGCGCGCTGAGGATGAAGCTGGCGCTGCCGAATGCCGAGCTCAGGGTGTT
TGCCAATGCCAGCCATATGCCCTTCTATGAAAACCCGCAGGATTTTTATCCGGCGCTTCTCGATTTTCTGGCCCGGCACG
AGGCAGGCTGA

Upstream 100 bases:

>100_bases
TACCCTATCACTTCTTATAGCTGGCACGGAACGCGATTTCCGGTAAAAAATTAACCACGCCCAAATATTGAGCAAGTGAA
ACCTTCTGCCGGAGCGGTCA

Downstream 100 bases:

>100_bases
TGCAAGAGGGAGCGGACCGGAGCCGACGAAGTCAAAGGGGCGATCGCCATCATGCATCGCTATAAATTCGTTCTGACGCG
ACCGTTGCAGTTCCTGCCCG

Product: proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP; Tricorn protease-interacting factor F1 [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MWREIQPDERFEIDVDGYRVVAYSFGTGSETIFCLNGGPGLPCDYLREAHSCLVEKGYRVIAFDQLGTGASDRPDDPSLW
TIGRYVEETETVRKALALGKVHMLGHSWGGWLAIEYALTYAQNLKTLILEDTVADMPHLISELERLRAALGPETVSMMQK
HEAQGTYNHPEYLAAVTILNYRHVCRLQEWPAPVRRSLDDWNMAPYETMQGPNEFLYIGNLKDWNRIADLPRLTLPVLIT
AGEHDELTPACALRMKLALPNAELRVFANASHMPFYENPQDFYPALLDFLARHEAG

Sequences:

>Translated_296_residues
MWREIQPDERFEIDVDGYRVVAYSFGTGSETIFCLNGGPGLPCDYLREAHSCLVEKGYRVIAFDQLGTGASDRPDDPSLW
TIGRYVEETETVRKALALGKVHMLGHSWGGWLAIEYALTYAQNLKTLILEDTVADMPHLISELERLRAALGPETVSMMQK
HEAQGTYNHPEYLAAVTILNYRHVCRLQEWPAPVRRSLDDWNMAPYETMQGPNEFLYIGNLKDWNRIADLPRLTLPVLIT
AGEHDELTPACALRMKLALPNAELRVFANASHMPFYENPQDFYPALLDFLARHEAG
>Mature_296_residues
MWREIQPDERFEIDVDGYRVVAYSFGTGSETIFCLNGGPGLPCDYLREAHSCLVEKGYRVIAFDQLGTGASDRPDDPSLW
TIGRYVEETETVRKALALGKVHMLGHSWGGWLAIEYALTYAQNLKTLILEDTVADMPHLISELERLRAALGPETVSMMQK
HEAQGTYNHPEYLAAVTILNYRHVCRLQEWPAPVRRSLDDWNMAPYETMQGPNEFLYIGNLKDWNRIADLPRLTLPVLIT
AGEHDELTPACALRMKLALPNAELRVFANASHMPFYENPQDFYPALLDFLARHEAG

Specific function: Cleaves H-Pro-AMC as well as a wide spectrum of amino acid substrates and several peptide substrates without a proline at the N-terminus. In conjunction with the three factors F1, F2 and F3, Tricorn degrades oligopeptides in a sequential manner, yielding

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005945
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 33583; Mature: 33583

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWREIQPDERFEIDVDGYRVVAYSFGTGSETIFCLNGGPGLPCDYLREAHSCLVEKGYRV
CCCCCCCCCCEEEECCCEEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEE
IAFDQLGTGASDRPDDPSLWTIGRYVEETETVRKALALGKVHMLGHSWGGWLAIEYALTY
EEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEHHHHHHH
AQNLKTLILEDTVADMPHLISELERLRAALGPETVSMMQKHEAQGTYNHPEYLAAVTILN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
YRHVCRLQEWPAPVRRSLDDWNMAPYETMQGPNEFLYIGNLKDWNRIADLPRLTLPVLIT
HHHHHHHHCCCHHHHCCCCCCCCCCHHHHCCCCCEEEECCCCCHHHHHCCCCCEEEEEEE
AGEHDELTPACALRMKLALPNAELRVFANASHMPFYENPQDFYPALLDFLARHEAG
CCCCCCCCHHHHHEEHEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MWREIQPDERFEIDVDGYRVVAYSFGTGSETIFCLNGGPGLPCDYLREAHSCLVEKGYRV
CCCCCCCCCCEEEECCCEEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEE
IAFDQLGTGASDRPDDPSLWTIGRYVEETETVRKALALGKVHMLGHSWGGWLAIEYALTY
EEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEHHHHHHH
AQNLKTLILEDTVADMPHLISELERLRAALGPETVSMMQKHEAQGTYNHPEYLAAVTILN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
YRHVCRLQEWPAPVRRSLDDWNMAPYETMQGPNEFLYIGNLKDWNRIADLPRLTLPVLIT
HHHHHHHHCCCHHHHCCCCCCCCCCHHHHCCCCCEEEECCCCCHHHHHCCCCCEEEEEEE
AGEHDELTPACALRMKLALPNAELRVFANASHMPFYENPQDFYPALLDFLARHEAG
CCCCCCCCHHHHHEEHEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726 [H]