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The map label for this gene is appC [H]

Identifier: 190894572

GI number: 190894572

Start: 234474

End: 235325

Strand: Reverse

Name: appC [H]

Synonym: RHECIAT_PC0000234

Alternate gene names: 190894572

Gene position: 235325-234474 (Counterclockwise)

Preceding gene: 190894573

Following gene: 190894571

Centisome position: 21.56

GC content: 63.38

Gene sequence:

>852_bases
ATGAGCGTCGAGGCGATCGTGCCTGCATCGCCCGGCTGGCGCCGGTTTTTCCGCCGGCAGCTGATGCTTGCCGTCGGTGC
CGGCCTGCTGCTGTTTTTCGTCCTGCTGGCAGTCGGCGCGCCCATCATCGCGCCCTATGACCCGATCATGCAGAATGCCG
AAGTGCGGCTGCAGGCGCCGTCATTGCTTCACCCGTTCGGCACCGACAATTTCGGCCGCGATATCCTGTCCCGCGTCATC
TGGGGCGCGCGCATCGACCTGCAGATGGCGCTGATCGGCGTCATCTTCCCCTTTCTGATCGGCACGACAGTCGGCACGGT
CGCCGGCTTCTTCGGCGGTATCGTCGATGCACTGTTCATGCGCTTAGTCGATATGATCCTCGCCTTCCCCTTTCTCGTGC
TGATGCTGTCGATCATCGCGATCCTTGGTCCCGGCCTCGGCAGCTTCTACATATCGATGGCGCTGGTCGGCTGGGTGTCC
TATGCGCGGCTGATCCGGGCGCAGATGCTGGTGCTGAAAAGCAGCGACTACGCCGTTGCCGCCGTCAGCCTCGGCTTCAG
CCGCCCACGCATCATGTTCCGCCACCTGCTGCCGAACGCGATCGCCGGGTCGATCGTCTTTTCAATGTCGGACGCGACGC
TGGTGCTGCTCAGCGGCGCCGCCGTCAGCTATCTCGGTCTCGGCGTACAGCCGCCGATCGCCGAATGGGGCGTGATGGTT
GCGGAAGGGCAGAGTTTCATCACCACCGCCTGGTGGATCACCCTGTTTCCCGGTCTCTCCATCGTCTGCCTCGCCTTTGG
TTTCAGCATGCTGGGCGATGCTCTCGGCGAATTGCTGGGGGTGCACGAATGA

Upstream 100 bases:

>100_bases
TGGTGGTTCAGGGCGTCGCCATGGTCTTTGCCTGCGCCACGGTGTTCATCAATTTCCTCGCCGACATCGTCACCGTCGCC
GTCGATCCGAGGGTGAAGTT

Downstream 100 bases:

>100_bases
GCGGCTCGCTGCTCTCCGTCCGCGATCTGACTGTCAGGGCGCATGCCGAACCCGGTCCACGCACGCTGCTCGACGCGGTG
TCGCTCGATCTCGGCAAGGG

Product: putative dipeptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MSVEAIVPASPGWRRFFRRQLMLAVGAGLLLFFVLLAVGAPIIAPYDPIMQNAEVRLQAPSLLHPFGTDNFGRDILSRVI
WGARIDLQMALIGVIFPFLIGTTVGTVAGFFGGIVDALFMRLVDMILAFPFLVLMLSIIAILGPGLGSFYISMALVGWVS
YARLIRAQMLVLKSSDYAVAAVSLGFSRPRIMFRHLLPNAIAGSIVFSMSDATLVLLSGAAVSYLGLGVQPPIAEWGVMV
AEGQSFITTAWWITLFPGLSIVCLAFGFSMLGDALGELLGVHE

Sequences:

>Translated_283_residues
MSVEAIVPASPGWRRFFRRQLMLAVGAGLLLFFVLLAVGAPIIAPYDPIMQNAEVRLQAPSLLHPFGTDNFGRDILSRVI
WGARIDLQMALIGVIFPFLIGTTVGTVAGFFGGIVDALFMRLVDMILAFPFLVLMLSIIAILGPGLGSFYISMALVGWVS
YARLIRAQMLVLKSSDYAVAAVSLGFSRPRIMFRHLLPNAIAGSIVFSMSDATLVLLSGAAVSYLGLGVQPPIAEWGVMV
AEGQSFITTAWWITLFPGLSIVCLAFGFSMLGDALGELLGVHE
>Mature_282_residues
SVEAIVPASPGWRRFFRRQLMLAVGAGLLLFFVLLAVGAPIIAPYDPIMQNAEVRLQAPSLLHPFGTDNFGRDILSRVIW
GARIDLQMALIGVIFPFLIGTTVGTVAGFFGGIVDALFMRLVDMILAFPFLVLMLSIIAILGPGLGSFYISMALVGWVSY
ARLIRAQMLVLKSSDYAVAAVSLGFSRPRIMFRHLLPNAIAGSIVFSMSDATLVLLSGAAVSYLGLGVQPPIAEWGVMVA
EGQSFITTAWWITLFPGLSIVCLAFGFSMLGDALGELLGVHE

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=274, Percent_Identity=37.2262773722628, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1787760, Length=251, Percent_Identity=37.0517928286853, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1789964, Length=285, Percent_Identity=36.8421052631579, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789889, Length=238, Percent_Identity=34.453781512605, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1787498, Length=272, Percent_Identity=30.1470588235294, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787549, Length=267, Percent_Identity=28.8389513108614, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788505, Length=192, Percent_Identity=27.6041666666667, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30425; Mature: 30294

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEAIVPASPGWRRFFRRQLMLAVGAGLLLFFVLLAVGAPIIAPYDPIMQNAEVRLQAP
CCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEECC
SLLHPFGTDNFGRDILSRVIWGARIDLQMALIGVIFPFLIGTTVGTVAGFFGGIVDALFM
CHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLVDMILAFPFLVLMLSIIAILGPGLGSFYISMALVGWVSYARLIRAQMLVLKSSDYAVA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
AVSLGFSRPRIMFRHLLPNAIAGSIVFSMSDATLVLLSGAAVSYLGLGVQPPIAEWGVMV
EHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCEEEEECCHHHHHHCCCCCCCHHHHCEEH
AEGQSFITTAWWITLFPGLSIVCLAFGFSMLGDALGELLGVHE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVEAIVPASPGWRRFFRRQLMLAVGAGLLLFFVLLAVGAPIIAPYDPIMQNAEVRLQAP
CCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEECC
SLLHPFGTDNFGRDILSRVIWGARIDLQMALIGVIFPFLIGTTVGTVAGFFGGIVDALFM
CHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLVDMILAFPFLVLMLSIIAILGPGLGSFYISMALVGWVSYARLIRAQMLVLKSSDYAVA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
AVSLGFSRPRIMFRHLLPNAIAGSIVFSMSDATLVLLSGAAVSYLGLGVQPPIAEWGVMV
EHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCEEEEECCHHHHHHCCCCCCCHHHHCEEH
AEGQSFITTAWWITLFPGLSIVCLAFGFSMLGDALGELLGVHE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]