Click here to switch to the map view.

The map label for this gene is tldD [H]

Identifier: 190571345

GI number: 190571345

Start: 1016103

End: 1017533

Strand: Direct

Name: tldD [H]

Synonym: WPa_0950

Alternate gene names: 190571345

Gene position: 1016103-1017533 (Clockwise)

Preceding gene: 190571342

Following gene: 190571352

Centisome position: 68.54

GC content: 36.55

Gene sequence:

>1431_bases
ATGCCAAATCTAGATCAAATATTTTTTGCTCAGAACAATGTTAATATTAATAATGTATATAAAATAGTCAACAACGCTTT
GAGCAATAGTGATGGTGGTGAGCTATTTTTAGAGTTTTGCCAATCAGAATCCCTGATTTTTGATGATAATATATTAAAAC
ATATGGATTTAAATATCAGAAGAGGATTTGGTCTCAGGTCTTTTTGTGAAGATAGTACGTCTTTTGTTTGCTCTTCTGAG
ATTAGCGAAAAAGAAATTAGTAAAGCTGCTTCTATGGTAAAAAGTTCAGCATCTTTAAGCAAAACAAATTCAGTAAACTT
AAATGAGGAGGCAAAAAGCCTGTATTCAAAGATTAATCCCATAAATGAAATGGATCTGAGCTCAAAAATTAAACTACTCA
ATGAGATTAATGAGTATGTAAGGTCGAAGAATAACTGCGTGAAGCAGGTAAAAATAACTCTAAATGGAGAATGGCAAGTT
GTACAAATAATAAAAGATGATCACAGGTTAAGCGATATCAGGCCTTTGGTACGTTTTAATGTACTAGTCATCGTAGAGAA
AAATGGCCGAGCAGAGAGAGGTTCTGCAGGGCACGGTGGAAGAGACTCTTATAGTAAATTTGTTTCTGAGAAGAAGTGGA
AAAAAGTTGCAAACCAAGCGTTAGAACAAGCGCTAGTAAATCTTGAGGCAATTCCAGCTCCGGCTGGAGAGATGACAGTT
GTTTTAGGTTCAGGTTGGCCAGGAATATTATTGCATGAAGCTGTAGGTCATGGACTTGAAGGTGATTTTAACCGTAAAGG
AATCTCGGCATTTTCAAATTCTATGGGTAAACAAGTGGCAGCCAGTAACATTACTGTAATTGATGATGGAACTCTACCTA
ATTTGCGTGGTTCTATTAGCATAGACGATGAGGGTACTTTACCTGGCTATAATGTGCTTATAGAAGATGGAATTCTAAAA
GGATATATGCAAGATCATATGAACGCTAAACTTATGGGTGTAAATCCAACTGGTAATGGTAGAAGAGAAAGTTACAAAGA
AGTTACTATGCCACGCATGACAAACACCTATATGTTGGCAGGAAAATATGCACCAGAAGAAATAATATCCAGTGTAAAAA
GAGGCCTATATGCAGTAAATTTTGGTGGTGGACAAGTTGATATAACATCAGGAAAATTTGTTTTCTCATCTTCAGAAGCT
TACCTAATAGAAAATGGTAAAATTACACAGCCAGTGAAAGGAGCAACACTAATTGGTGATGGGCCAACAGTGCTAAAAAA
AGTATCAATGATTGGTAATGATCTAAAGTTAGATCCTGGTGTTGGTACGTGCTCAAAAGACGGGCAAAATGTGCCTGTTG
GAGTTGGTCAGCCAACACTCAAGGTCGATGCAATAACTGTTGGTGGAACTGAATATGTAGATAAGGGCTAA

Upstream 100 bases:

>100_bases
CCTGAAGCTAGCGCGTCTACCAATTCCGCCACCCGGGCTTTTTGTGATTTACTATGTTAAAATTAAATAATATACTTAAA
CAATTTTTAGCTCAAAGGTA

Downstream 100 bases:

>100_bases
GCGAACTCAGCTCATGCTGTACAATTGTACAAATATTGTAACCATTATTCAAGTAGCTCATATAGATGCAAAAACTACTT
AACAAATCTCTCTGCCTTCC

Product: tldD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MPNLDQIFFAQNNVNINNVYKIVNNALSNSDGGELFLEFCQSESLIFDDNILKHMDLNIRRGFGLRSFCEDSTSFVCSSE
ISEKEISKAASMVKSSASLSKTNSVNLNEEAKSLYSKINPINEMDLSSKIKLLNEINEYVRSKNNCVKQVKITLNGEWQV
VQIIKDDHRLSDIRPLVRFNVLVIVEKNGRAERGSAGHGGRDSYSKFVSEKKWKKVANQALEQALVNLEAIPAPAGEMTV
VLGSGWPGILLHEAVGHGLEGDFNRKGISAFSNSMGKQVAASNITVIDDGTLPNLRGSISIDDEGTLPGYNVLIEDGILK
GYMQDHMNAKLMGVNPTGNGRRESYKEVTMPRMTNTYMLAGKYAPEEIISSVKRGLYAVNFGGGQVDITSGKFVFSSSEA
YLIENGKITQPVKGATLIGDGPTVLKKVSMIGNDLKLDPGVGTCSKDGQNVPVGVGQPTLKVDAITVGGTEYVDKG

Sequences:

>Translated_476_residues
MPNLDQIFFAQNNVNINNVYKIVNNALSNSDGGELFLEFCQSESLIFDDNILKHMDLNIRRGFGLRSFCEDSTSFVCSSE
ISEKEISKAASMVKSSASLSKTNSVNLNEEAKSLYSKINPINEMDLSSKIKLLNEINEYVRSKNNCVKQVKITLNGEWQV
VQIIKDDHRLSDIRPLVRFNVLVIVEKNGRAERGSAGHGGRDSYSKFVSEKKWKKVANQALEQALVNLEAIPAPAGEMTV
VLGSGWPGILLHEAVGHGLEGDFNRKGISAFSNSMGKQVAASNITVIDDGTLPNLRGSISIDDEGTLPGYNVLIEDGILK
GYMQDHMNAKLMGVNPTGNGRRESYKEVTMPRMTNTYMLAGKYAPEEIISSVKRGLYAVNFGGGQVDITSGKFVFSSSEA
YLIENGKITQPVKGATLIGDGPTVLKKVSMIGNDLKLDPGVGTCSKDGQNVPVGVGQPTLKVDAITVGGTEYVDKG
>Mature_475_residues
PNLDQIFFAQNNVNINNVYKIVNNALSNSDGGELFLEFCQSESLIFDDNILKHMDLNIRRGFGLRSFCEDSTSFVCSSEI
SEKEISKAASMVKSSASLSKTNSVNLNEEAKSLYSKINPINEMDLSSKIKLLNEINEYVRSKNNCVKQVKITLNGEWQVV
QIIKDDHRLSDIRPLVRFNVLVIVEKNGRAERGSAGHGGRDSYSKFVSEKKWKKVANQALEQALVNLEAIPAPAGEMTVV
LGSGWPGILLHEAVGHGLEGDFNRKGISAFSNSMGKQVAASNITVIDDGTLPNLRGSISIDDEGTLPGYNVLIEDGILKG
YMQDHMNAKLMGVNPTGNGRRESYKEVTMPRMTNTYMLAGKYAPEEIISSVKRGLYAVNFGGGQVDITSGKFVFSSSEAY
LIENGKITQPVKGATLIGDGPTVLKKVSMIGNDLKLDPGVGTCSKDGQNVPVGVGQPTLKVDAITVGGTEYVDKG

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=473, Percent_Identity=51.1627906976744, Blast_Score=462, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51684; Mature: 51553

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNLDQIFFAQNNVNINNVYKIVNNALSNSDGGELFLEFCQSESLIFDDNILKHMDLNIR
CCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEECCCHHHHCCCEEE
RGFGLRSFCEDSTSFVCSSEISEKEISKAASMVKSSASLSKTNSVNLNEEAKSLYSKINP
CCCCCHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
INEMDLSSKIKLLNEINEYVRSKNNCVKQVKITLNGEWQVVQIIKDDHRLSDIRPLVRFN
CCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEECCCCHHHHHHHEEEEE
VLVIVEKNGRAERGSAGHGGRDSYSKFVSEKKWKKVANQALEQALVNLEAIPAPAGEMTV
EEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VLGSGWPGILLHEAVGHGLEGDFNRKGISAFSNSMGKQVAASNITVIDDGTLPNLRGSIS
EEECCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEE
IDDEGTLPGYNVLIEDGILKGYMQDHMNAKLMGVNPTGNGRRESYKEVTMPRMTNTYMLA
ECCCCCCCCCEEEEECHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCCCCEEEEE
GKYAPEEIISSVKRGLYAVNFGGGQVDITSGKFVFSSSEAYLIENGKITQPVKGATLIGD
CCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEEECCCCCCCCCCCEEECC
GPTVLKKVSMIGNDLKLDPGVGTCSKDGQNVPVGVGQPTLKVDAITVGGTEYVDKG
CHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCHHCCCC
>Mature Secondary Structure 
PNLDQIFFAQNNVNINNVYKIVNNALSNSDGGELFLEFCQSESLIFDDNILKHMDLNIR
CCCCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEECCCHHHHCCCEEE
RGFGLRSFCEDSTSFVCSSEISEKEISKAASMVKSSASLSKTNSVNLNEEAKSLYSKINP
CCCCCHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
INEMDLSSKIKLLNEINEYVRSKNNCVKQVKITLNGEWQVVQIIKDDHRLSDIRPLVRFN
CCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEECCCCHHHHHHHEEEEE
VLVIVEKNGRAERGSAGHGGRDSYSKFVSEKKWKKVANQALEQALVNLEAIPAPAGEMTV
EEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VLGSGWPGILLHEAVGHGLEGDFNRKGISAFSNSMGKQVAASNITVIDDGTLPNLRGSIS
EEECCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEE
IDDEGTLPGYNVLIEDGILKGYMQDHMNAKLMGVNPTGNGRRESYKEVTMPRMTNTYMLA
ECCCCCCCCCEEEEECHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCCCCEEEEE
GKYAPEEIISSVKRGLYAVNFGGGQVDITSGKFVFSSSEAYLIENGKITQPVKGATLIGD
CCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEEECCCCCCCCCCCEEECC
GPTVLKKVSMIGNDLKLDPGVGTCSKDGQNVPVGVGQPTLKVDAITVGGTEYVDKG
CHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]