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The map label for this gene is tlyC [H]

Identifier: 190571244

GI number: 190571244

Start: 920992

End: 921810

Strand: Direct

Name: tlyC [H]

Synonym: WPa_0844

Alternate gene names: 190571244

Gene position: 920992-921810 (Clockwise)

Preceding gene: 190571239

Following gene: 190571245

Centisome position: 62.13

GC content: 30.16

Gene sequence:

>819_bases
TTGAATAAGAAAAGAACTTTAGTAGAAAAAATAGCATACAAAATTTTTTTCTTTCTCTTCAACAAAACTTCTGTGTTAAA
AAAATGTGCGACTGAGGCATTAATGGGTGATCTGTCAGGTCTTGACATACTTAATAGTCTATTAAAATTCCGTGATTGTA
GTATCATGGATATAATGACTCCACGTAAGGAGATATGTGCAATAGACATTGAATCGAGCAAGGATGAGGTAATAAAGAAG
GTGAAAAACACTTACCATGCTAAGATACCAACTTATAAGAATAACTTTGACAACGTAATAGGCTTTTTTTACGTAAAAGA
TATCATTTTCAATAAGAATAAAGATTTTAATCTGAGAAATATTATACAAAATGTAATATTTGTCCCAGCCTCAATGAAAG
CAACAAATCTTTTTGTTAGAATGAAATCTTCCAAGTCATATTTAGCTATTGTACTGGATGAATATGGCGGAACTGATGGT
TTAATTTCGATAAATGATCTTATAGAAGAATTGATACCAAATATTGATAACGAGAATGAGGTAAATTCAGAACACACCAT
TACTGAATTATCTCAAAATAAGTTTGAAATATCGGCAAGGGCCCTTATAAAGGATATAGAGGAAAATCTAAAAATAGAGT
TGTGTGACTCTGAAGAGCATTATGCCACACTTAGTGGTTTGGTTCTTTCAATTGCTGGTAAGGTACCTTCTGTAGATGAA
GTTATAAGATATAAAAATGGTATAAAATTTATCATCAAGGATGCAAATGAACGATACATTAACAAAATAATACTAGACTT
AAGTGATTACAAAAATTAA

Upstream 100 bases:

>100_bases
ACAAATTAATTTGACATTATTCACATGCTTATTAAACATTTAATAACAGTTTTCTTGATAGACCTTATCTAAAGATATTT
TCACCATTAAAGGGAATAAA

Downstream 100 bases:

>100_bases
ATTCAATATTTTTTAGTGAAAGGTACTTTATCTTGGAAGTAGGAGACATAGTAGCCAGGTATGCAATTTAAACAATTTCT
TAATATACAAAAGTTTGTAG

Product: CBS domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MNKKRTLVEKIAYKIFFFLFNKTSVLKKCATEALMGDLSGLDILNSLLKFRDCSIMDIMTPRKEICAIDIESSKDEVIKK
VKNTYHAKIPTYKNNFDNVIGFFYVKDIIFNKNKDFNLRNIIQNVIFVPASMKATNLFVRMKSSKSYLAIVLDEYGGTDG
LISINDLIEELIPNIDNENEVNSEHTITELSQNKFEISARALIKDIEENLKIELCDSEEHYATLSGLVLSIAGKVPSVDE
VIRYKNGIKFIIKDANERYINKIILDLSDYKN

Sequences:

>Translated_272_residues
MNKKRTLVEKIAYKIFFFLFNKTSVLKKCATEALMGDLSGLDILNSLLKFRDCSIMDIMTPRKEICAIDIESSKDEVIKK
VKNTYHAKIPTYKNNFDNVIGFFYVKDIIFNKNKDFNLRNIIQNVIFVPASMKATNLFVRMKSSKSYLAIVLDEYGGTDG
LISINDLIEELIPNIDNENEVNSEHTITELSQNKFEISARALIKDIEENLKIELCDSEEHYATLSGLVLSIAGKVPSVDE
VIRYKNGIKFIIKDANERYINKIILDLSDYKN
>Mature_272_residues
MNKKRTLVEKIAYKIFFFLFNKTSVLKKCATEALMGDLSGLDILNSLLKFRDCSIMDIMTPRKEICAIDIESSKDEVIKK
VKNTYHAKIPTYKNNFDNVIGFFYVKDIIFNKNKDFNLRNIIQNVIFVPASMKATNLFVRMKSSKSYLAIVLDEYGGTDG
LISINDLIEELIPNIDNENEVNSEHTITELSQNKFEISARALIKDIEENLKIELCDSEEHYATLSGLVLSIAGKVPSVDE
VIRYKNGIKFIIKDANERYINKIILDLSDYKN

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=182, Percent_Identity=25.8241758241758, Blast_Score=90, Evalue=2e-18,
Organism=Escherichia coli, GI1786879, Length=231, Percent_Identity=25.5411255411255, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693175, Length=207, Percent_Identity=22.7053140096618, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788119, Length=205, Percent_Identity=23.9024390243902, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082033, Length=205, Percent_Identity=20.4878048780488, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790664, Length=246, Percent_Identity=21.1382113821138, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 31146; Mature: 31146

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKRTLVEKIAYKIFFFLFNKTSVLKKCATEALMGDLSGLDILNSLLKFRDCSIMDIMT
CCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEECCC
PRKEICAIDIESSKDEVIKKVKNTYHAKIPTYKNNFDNVIGFFYVKDIIFNKNKDFNLRN
CCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
IIQNVIFVPASMKATNLFVRMKSSKSYLAIVLDEYGGTDGLISINDLIEELIPNIDNENE
HHHHHHCCCCCCCEEEEEEEEECCCCEEEEEEECCCCCCCEEEHHHHHHHHHCCCCCCCC
VNSEHTITELSQNKFEISARALIKDIEENLKIELCDSEEHYATLSGLVLSIAGKVPSVDE
CCCCHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCCCHHH
VIRYKNGIKFIIKDANERYINKIILDLSDYKN
HHHHHCCCEEEEECCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKKRTLVEKIAYKIFFFLFNKTSVLKKCATEALMGDLSGLDILNSLLKFRDCSIMDIMT
CCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEECCC
PRKEICAIDIESSKDEVIKKVKNTYHAKIPTYKNNFDNVIGFFYVKDIIFNKNKDFNLRN
CCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
IIQNVIFVPASMKATNLFVRMKSSKSYLAIVLDEYGGTDGLISINDLIEELIPNIDNENE
HHHHHHCCCCCCCEEEEEEEEECCCCEEEEEEECCCCCCCEEEHHHHHHHHHCCCCCCCC
VNSEHTITELSQNKFEISARALIKDIEENLKIELCDSEEHYATLSGLVLSIAGKVPSVDE
CCCCHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCCCHHH
VIRYKNGIKFIIKDANERYINKIILDLSDYKN
HHHHHCCCEEEEECCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA